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Home Other Building Blocks 1354707-41-7
1354707-41-7,MFCD31657404
Catalog No.:AA01EOBF

1354707-41-7 | Mitochonic acid 5

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥98%
in stock  
$112.00   $78.00
- +
10mg
≥98%
in stock  
$200.00   $140.00
- +
25mg
≥98%
in stock  
$390.00   $273.00
- +
50mg
≥98%
in stock  
$666.00   $466.00
- +
500mg
99% (HPLC)
in stock  
$4,996.00   $3,498.00
- +
1000mg
99% (HPLC)
in stock  
$7,957.00   $5,570.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EOBF
Chemical Name:
Mitochonic acid 5
CAS Number:
1354707-41-7
Molecular Formula:
C18H13F2NO3
Molecular Weight:
329.2975
MDL Number:
MFCD31657404
SMILES:
OC(=O)C(c1c[nH]c2c1cccc2)CC(=O)c1ccc(cc1F)F
Properties
Computed Properties
 
Complexity:
487  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.1  

Downstream Synthesis Route
CASUnavailable 
  1354707-64-4    1354707-41-7 

[1]CurrentPatentAssignee:TOHOKUUNIVERSITY-US2015/353489,2015,A1Locationinpatent:Paragraph0125;0126

[2]CurrentPatentAssignee:TOHOKUUNIVERSITY;KAKEEDUCATIONALINSTITUTION-US2019/224165,2019,A1Locationinpatent:Paragraph0093;0094;0104-0105

[3]CurrentPatentAssignee:TOHOKUUNIVERSITY;KAKEEDUCATIONALINSTITUTION-US2022/106270,2022,A1Locationinpatent:Paragraph0084-0085;0096-0097

[4]CurrentPatentAssignee:TOHOKUUNIVERSITY;KAKEEDUCATIONALINSTITUTION-US2022/106270,2022,A1Locationinpatent:Paragraph0084-0085;0096-0097

[5]CurrentPatentAssignee:TOHOKUUNIVERSITY;KAKEEDUCATIONALINSTITUTION-US2022/106270,2022,A1

[1]CurrentPatentAssignee:TOHOKUUNIVERSITY-US2015/353489,2015,A1

[2]CurrentPatentAssignee:TOHOKUUNIVERSITY;KAKEEDUCATIONALINSTITUTION-US2019/224165,2019,A1CurrentPatentAssignee:TOHOKUUNIVERSITY;KAKEEDUCATIONALINSTITUTION-US2022/106270,2022,A1

[3]CurrentPatentAssignee:TOHOKUUNIVERSITY;KAKEEDUCATIONALINSTITUTION-US2022/106270,2022,A1

Literature

Title: Suzuki T, et al. Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage. J Am Soc Nephrol. 2016 Jul;27(7):1925-32.

Title: Lei Q, et al. Mitochonic acid 5 activates the MAPK-ERK-yap signaling pathways to protect mouse microglial BV-2 cells against TNFα-induced apoptosis via increased Bnip3-related mitophagy. Cell Mol Biol Lett. 2018 Apr 5;23:14.

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SDS
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