Home Fluorides 372-18-9
372-18-9,MFCD00000327
Catalog No.:AA00I79K

372-18-9 | 1,3-Difluorobenzene

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Technical Information
Catalog Number:
AA00I79K
Chemical Name:
1,3-Difluorobenzene
CAS Number:
372-18-9
Molecular Formula:
C6H4F2
Molecular Weight:
114.0928
MDL Number:
MFCD00000327
SMILES:
Fc1cccc(c1)F
NSC Number:
10285
Properties
Properties
 
BP:
82.6°C  
Form:
Liquid  
MP:
-59 °C  
Refractive Index:
n20/D 1.438(lit.)  
Solubility:
1.1g/l  
Storage:
Room Temperature;Keep in dry area;  

Computed Properties
 
Complexity:
64.9  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
2.4  

Literature

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Journal: Acta crystallographica. Section E, Structure reports online 20120701

Title: 1-{(1Z)-1-[3-(2,4-Dichloro-phen-oxy)prop-oxy]-1-(2,4-difluoro-phen-yl)prop-1-en-2-yl}-1H-1,2,4-triazole.

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Title: Probing the interaction of archaeal DNA polymerases with deaminated bases using X-ray crystallography and non-hydrogen bonding isosteric base analogues.

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Title: Intramolecular halogen stabilization of silylium ions directs gearing dynamics.

Journal: Journal of the American Chemical Society 20100616

Title: Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole.

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Title: Synthesis and biological evaluation of salicylic acid and N-acetyl-2-carboxybenzenesulfonamide regioisomers possessing a N-difluoromethyl-1,2-dihydropyrid-2-one pharmacophore: dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.

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Title: Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases.

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Tags:372-18-9 Molecular Formula|372-18-9 MDL|372-18-9 SMILES|372-18-9 1,3-Difluorobenzene |Fluorinated_Building_Blocks