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Home Other Building Blocks 1314873-02-3
1314873-02-3,MFCD30532675
Catalog No.:AA01EOFT

1314873-02-3 | BPO-27 racemate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$135.00   $95.00
- +
5mg
95%
1 week  
$284.00   $199.00
- +
10mg
95%
1 week  
$397.00   $278.00
- +
25mg
95%
1 week  
$620.00   $434.00
- +
50mg
95%
1 week  
$878.00   $615.00
- +
100mg
95%
1 week  
$1,191.00   $834.00
- +
200mg
95%
1 week  
$1,578.00   $1,104.00
- +
500mg
95%
1 week  
$2,320.00   $1,624.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EOFT
Chemical Name:
BPO-27 racemate
CAS Number:
1314873-02-3
Molecular Formula:
C26H18BrN3O6
Molecular Weight:
548.3416
MDL Number:
MFCD30532675
SMILES:
Brc1ccc(o1)C1Oc2ccc(cc2n2c1c1c(c2c2ccccc2)c(=O)n(c(=O)n1C)C)C(=O)O
Properties
Computed Properties
 
Complexity:
914  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.8  

Literature

Title: Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease.

Journal: Journal of medicinal chemistry 20110811

Title: Snyder DS, et al. Absolute Configuration And Biological Properties of Enantiomers of CFTR Inhibitor BPO-27. ACS Med Chem Lett. 2013 May 9;4(5):456-459.

Title: Kim Y, et al. Benzopyrimido-pyrrolo-oxazine-dione (R)-BPO-27 Inhibits CFTR Chloride Channel Gating by Competition with ATP. Mol Pharmacol. 2015 Oct;88(4):689-96.

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SDS
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Tags:1314873-02-3 Molecular Formula|1314873-02-3 MDL|1314873-02-3 SMILES|1314873-02-3 BPO-27 racemate