1015073-42-3,MFCD28386293
Catalog No.:AA01EOQ4

1015073-42-3 | PSI-7409

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
>98.00%
3 weeks  
$717.00   $502.00
- +
5mg
>98.00%
3 weeks  
$1,577.00   $1,104.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01EOQ4
Chemical Name:
PSI-7409
CAS Number:
1015073-42-3
Molecular Formula:
C10H16FN2O14P3
Molecular Weight:
500.1587
MDL Number:
MFCD28386293
SMILES:
O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@]1(C)F)n1ccc(=O)[nH]c1=O
Properties
Computed Properties
 
Complexity:
891  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
15  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0  
Rotatable Bond Count:
8  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-4.9  

Literature

Title: PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.

Journal: Antimicrobial agents and chemotherapy 20100801

Title: Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species.

Journal: The Journal of biological chemistry 20071012

Title: Lam AM, et al. PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication. Antimicrob Agents Chemother. 2010 Aug;54(8):3187-96.

Title: Murakami E, et al. Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977.

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SDS
Tags:1015073-42-3 Molecular Formula|1015073-42-3 MDL|1015073-42-3 SMILES|1015073-42-3 PSI-7409
Catalog No.: AA01EOQ4
1015073-42-3,MFCD28386293
1015073-42-3 | PSI-7409
Pack Size: 1mg
Purity: >98.00%
3 weeks
$717.00 $502.00
Pack Size: 5mg
Purity: >98.00%
3 weeks
$1,577.00 $1,104.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01EOQ4
Chemical Name: PSI-7409
CAS Number: 1015073-42-3
Molecular Formula: C10H16FN2O14P3
Molecular Weight: 500.1587
MDL Number: MFCD28386293
SMILES: O[C@@H]1[C@@H](COP(=O)(OP(=O)(OP(=O)(O)O)O)O)O[C@H]([C@]1(C)F)n1ccc(=O)[nH]c1=O
Properties
Complexity: 891  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 4  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 30  
Hydrogen Bond Acceptor Count: 15  
Hydrogen Bond Donor Count: 6  
Isotope Atom Count: 0  
Rotatable Bond Count: 8  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -4.9  
Literature fold

Title: PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication.

Journal: Antimicrobial agents and chemotherapy20100801

Title: Characterization of the metabolic activation of hepatitis C virus nucleoside inhibitor beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine (PSI-6130) and identification of a novel active 5'-triphosphate species.

Journal: The Journal of biological chemistry20071012

Title: Lam AM, et al. PSI-7851, a pronucleotide of beta-D-2'-deoxy-2'-fluoro-2'-C-methyluridine monophosphate, is a potent and pan-genotype inhibitor of hepatitis C virus replication. Antimicrob Agents Chemother. 2010 Aug;54(8):3187-96.

Title: Murakami E, et al. Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977.

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