InCl3-catalyzed one-pot synthesis of multi-substituted pyrano[2,3-c]pyrazole-4-carboxylic acid esters under ultrasound irradiation

Jie Liang1 · Mengnisa Seydimemet1 · Zulpiya Ghalip1 · Keyume Ablajan1
Received: 27 February 2018 / Accepted: 2 August 2018 / Published online: 17 August 2018
© Springer Nature Switzerland AG 2018

Introduction
A series of 6-amino-5-cyano-4-phenylpyrano[2,3-c] pyrazole-4-carboxylic acid esters was synthesized via the four-component one-pot reaction of ethyl acetoacetate, hydrazine, methyl phenylglyoxylate, and malononitrile in the presence of InCl3 in 50% EtOH medium under ultrasound irradiation at 40 °C for 20 min. The ever-growing need for new chemicals is being met by organic chemists’ efforts to synthesize novel structures bearing various rings such as pyrans, pyrazoles, and pyrimidines [1]. The pyranopyrazole ring, a productive source of biologically active molecules [2], is attracting increasing interest from chemists. Heterocyclic compounds containing pyranones and pyrazolines have been widely investigated for their potentially useful bioactivity [3, 4]. The synthesis of pyrano[2,3-c]pyrazoles has received much attention owing to their antimicrobial [5], anti-inflammatory [6], anti-tumor, and antifungal [7] activities. They have also been useful in combating schizophrenia, Alzheimer’s, and mycolonous diseases [8]. Additionally, pyranopyrazole derivatives have been reported to show vast utility in biodegradable agrochemicals, pigments, cosmetics, and photoactive materials.[9]. Much recent research has focused on the synthesis of multi-substituted dihydro-pyrano[2,3-c]pyrazoles with various functional groups [10].

Multicomponent reactions (MCRs) are widely employed to make bioactive scaffolds [11] and complex heterocycles [12]. They involve three or more reactants that form three or more chemical bonds incorporated into a single molecule via one-pot domino or tandem reactions. Many studies have proved that MCRs show atom economy, short reaction times, and high efficiency. They are thus widely applied in synthetic chemistry, medicine, and agrochemistry [13].

However, establishing a convenient and efficient approach for the synthesis of pyrano[2,3-c]pyrazoles remains challenging. Various methods have been reported for the synthesis of substituted pyrano[2,3-c]pyrazoles involving different metal catalysts such as nano-TiO2/H14[NaP5W30O110] [14], P4VPyCuI [15], and ZrO2 NPs [16]. In addition, multi-substituted pyrano[2,3-c]pyrazole derivatives have been obtained in good yields under catalysis by triethylamine [17] and metalfree or solvent-free conditions [18, 19]. Although most of the above-mentioned methods offer some advantages, they also suffer from disadvantages such as long reaction times, operational complexity, and the use of rare or expensive catalysts. InCl3 is an effective Lewis acid catalyst [20, 21] and has a high affinity toward acetylenic
bonds [22], intermolecular [23] and intramolecular [24] reactions of arenes with allyl acetates, and allyl bromides.

Ultrasound irradiation is increasingly being used in synthetic chemistry because it allows quicker and more selective reactions with excellent yields in comparison with conventional methods [25]: Ultrasonic-accelerated reactions complete more quickly and under more moderate conditions [26]. Therefore, we designed a facile and efficient method for the synthesis of pyrano[2,3-c]pyrazole derivatives via MCRs in 50% EtOH catalyzed by InCl3 under ultrasound irradiation (Scheme 1). The products contained various functional groups that have various useful applications.

Results and discussion
To establish optimal reaction conditions, the four-component one-pot reaction was explored using ethyl acetoacetate 1a, hydrazine hydrate 2, methyl phenylglyoxylate 3a, and malononitrile 4 in 50% EtOH catalyzed by InCl3 under ultrasound irradiation as a model reaction. This reaction did not occur in the absence of InCl3 (Table 1, entry 1). Different concentrations of catalyst (5, 10, 20, and 30 mol%) were then screened for this reaction, and the product 5a was obtained in excellent yields (85–95%, Table 1, entries 2–5). The optimal concentration of 20 mol% InCl3 obtained the highest yield with a relatively small amount of catalyst (entry 4). Various other catalysts (Et3N, piperidine, TEBA, Na2CO3, and KOH) were then tested with the model reaction (Table 1, entries 6–10), showing that organic alkali produced higher yields than inorganic bases. Overall, catalyst screening indicated that the best yield (95%) was obtained using InCl3 (20 mol%) (Table 1, entry 4).

Six different solvents were then screened to find the best for the synthesis of compound 5a using InCl3 (20 mol%) catalyst under ultrasound irradiation at 40 °C for 20 min. The results (Table 2, entries 1–6) show that 50% EtOH was more effective than 99% EtOH, H2O, THF, CH2Cl2, and MeOH (Table 2, entry 2, 95% yield). Furthermore, the model reaction with InCl3 (20 mol%) under ultrasound irradiation at 40 °C was performed for 5, 10, and 30 min (entries 7–9). Changing the reaction time did not improve the yield originally obtained after 20 min (Table 2, entry 2). The reaction temperature was next varied (from 20 to 60 °C, Table 2, entries 10–12) under ultrasound irradiation, showing that the yield was improved as the temperature increased to 40 °C, above which it reached a plateau.

Therefore, the most suitable reaction temperature is 40 °C. Finally, the scope of this process was tested by synthesizing multi-substituted pyrano[2,3-c]pyrazole-4-carboxylic acid ester derivatives in the presence of InCl3 (20 mol%) in 50% EtOH under ultrasound irradiation at 40 °C for 20 min.

The results summarized in Table 3 show that compounds 5a–5t were successfully obtained under the optimized reaction conditions. Whether electron-rich or electron-deficient hydrazine derivatives were used, they were well tolerated in this protocol to produce the corresponding compounds in excellent yields (80%–95%). Ultrasonic irradiation played an important role in shortening the reaction time and enhancing the yields. The structures of all synthesized compounds 5a–5t were corroborated by NMR, IR, and ESI–MS spectroscopy. Detailed spectral data and spectra of all compounds are listed in supporting information. Scheme 2 depicts the most plausible reaction mechanism for the formation of product 5. One molecule of malononitrile is first condensed with the methyl benzoylacetate, catalyzed
by InCl3, to afford intermediate C. It is reasonable to assume that A results from the initial reaction of hydrazine 2 with β-ketoester 1. Pyrazolone A loses a proton under InCl3 to give B. Subsequent nucleophilic attack by the active methylene of B on C gives intermediate D, which further produces the desired product 5 followed by tautomerization.

Conclusion
In summary, a series of 6-amino-5-cyano-4-phenylpyrano[2,3-c] pyrazole-4-carboxylic acid esters was synthesized via the four-component one-pot reaction of ethyl acetoacetate, hydrazine, methyl phenylglyoxylate, and malononitrile in the presence of InCl3 (20 mol%) in 50% EtOH medium under ultrasound irradiation at 40 °C for 20 min. Promising characteristics of the presented methodology are efficiency, simplicity, high yield, short reaction time, ease of product isolation, and agreement with green chemistry protocols, making it a useful and attractive process for the synthesis of pyrano[2,3-c] pyrazole derivatives.

Experimental
Reagents and apparatus
Melting points were determined on a Buchi B-540 digital melting point apparatus using an open-ended capillary tube and are uncorrected. A Bruker (Advance) 400 MHz NMR instrument recorded 1H and 13C NMR spectra at 400 MHz and 100 MHz using TMS as an internal standard and DMSOd6 as solvent. Chemical shifts are given in parts per million, and the coupling constants are given in hertz. Infrared (IR) spectra were recorded with a Bruker Equinox55 instrument using KBr pellets. Band positions are reported in reciprocal centimeter (cm−1); HRMS was conducted with a Micromass Q-TOF Global Tandem

Mass Spectrometer, and MS spectra were detected with an MSD1–MS instrument (LC–MS, ESI source). Sonication was performed in a Branson CQX ultrasonic cleaner (frequency 25 kHz; nominal power 250 W). The chemicals used in this study were of analytical purity and were purchased from TCI, Alfa, Acros, etc. General procedure for the four-component one-pot synthesis of 6-amino-5-cyano-3-methyl-4-phenyl-2,4-dihydro-pyrano [2,3-c]pyrazole-4-carboxylic acid methyl ester 5a–5t To a 25-mL Erlenmeyer flask charged with a mixture of ethyl acetoacetate (2.0 mmol) and hydrazine hydrate (2.0 mmol) was added dropwise a solution of methyl benzoylformate (2.0 mmol), malononitrile (2.0 mmol), and InCl3 (20 mol%) in 50% EtOH (5 mL). The reaction flask was then irradiated in the water bath of an ultrasonic cleaner (frequency 25 kHz;nominal power 250 W) at 40 °C for 20 min). The reaction was monitored by TLC. After completion of the reaction, the mixture was allowed to cool to room temperature, and an
equal volume of water was added. White or colorless crystals were obtained through filtration via sequential washing with water and ethylacetate. A pure product was obtained by crystallization in 95% EtOH.

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Penciclovir-d4 Catalog No.:AA0006HI CAS No.:1020719-72-5 MDL No.:MFCD07369334 MF:C10H11D4N5O3 MW:257.2824	Risperidone-d4 Catalog No.:AA0006HH CAS No.:1020719-76-9 MDL No.:MFCD07369642 MF:C23H23D4FN4O2 MW:414.5091
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3-Fluoro-4-(2-methoxyphenoxy)benzoic acid Catalog No.:AA00H9OD CAS No.:1021245-91-9 MDL No.:MFCD12452316 MF:C14H11FO4 MW:262.2331	Ancitabine hydrochloride Catalog No.:AA00H9OA CAS No.:10212-25-6 MDL No.:MFCD00012636 MF:C9H12ClN3O4 MW:261.6623
3,7-Dichloro-1-(4-methoxybenzyl)quinoxalin-2(1H)-one Catalog No.:AA00IUGH CAS No.:1021179-88-3 MDL No.:MFCD28127026 MF:C16H12Cl2N2O2 MW:335.1847	5,5-dimethyl-3-[(1H-1,2,3,4-tetrazol-5-yl)amino]cyclohex-2-en-1-one Catalog No.:AA00IX5X CAS No.:1021273-24-4 MDL No.:MFCD00129606 MF:C9H13N5O MW:207.2324
3-{[2-(propan-2-yl)-1H-imidazol-1-yl]methyl}aniline Catalog No.:AA00J17X CAS No.:1021062-16-7 MDL No.:MFCD11149306 MF:C13H17N3 MW:215.2942	3-(thiophen-3-yl)-1,2-oxazol-5-amine Catalog No.:AA00J8BP CAS No.:1020955-36-5 MDL No.:MFCD11156304 MF:C7H6N2OS MW:166.2003
5-(Chloromethyl)-3-(1-phenylethyl)-1,2,4-oxadiazole Catalog No.:AA00S3U5 CAS No.:1021436-49-6 MDL No.:MFCD18425662 MF:C11H11ClN2O MW:222.6708	[(2,4-Difluorophenyl)methyl](propan-2-yl)amine Catalog No.:AA019LOM CAS No.:1021091-66-6 MDL No.:MFCD11138909 MF:C10H13F2N MW:185.2137
[2-(4-fluorophenyl)ethyl](2-methylpropyl)amine Catalog No.:AA019LQW CAS No.:1020951-24-9 MDL No.:MFCD11141716 MF:C12H18FN MW:195.2764	4-{[(4-fluoro-2-methylphenyl)amino]methyl}benzonitrile Catalog No.:AA019LTC CAS No.:1021080-21-6 MDL No.:MFCD11146552 MF:C15H13FN2 MW:240.2755
N-[(oxolan-2-yl)methyl]thiolan-3-amine Catalog No.:AA019M9X CAS No.:1021130-21-1 MDL No.:MFCD10686760 MF:C9H17NOS MW:187.3024	2-[(2-methoxyethyl)amino]-N,N-dimethylacetamide Catalog No.:AA019MWX CAS No.:1021114-96-4 MDL No.:MFCD11099615 MF:C7H16N2O2 MW:160.2141
METHYL 2-[(2,2,2-TRIFLUOROETHYL)AMINO]ACETATE Catalog No.:AA019NF4 CAS No.:1021235-22-2 MDL No.:MFCD11154790 MF:C5H8F3NO2 MW:171.1177	3-(6-Bromo-4-oxo-3,4-dihydroquinazolin-3-yl)propanoic acid Catalog No.:AA019PE7 CAS No.:102118-19-4 MDL No.:MFCD09040369 MF:C11H9BrN2O3 MW:297.1048
3-fluoro-4-(1H-1,2,4-triazol-1-yl)benzoic acid Catalog No.:AA019QWM CAS No.:1020934-33-1 MDL No.:MFCD11156563 MF:C9H6FN3O2 MW:207.1612	5-(thiophen-2-ylsulfanyl)pyridin-2-amine Catalog No.:AA019RGC CAS No.:1021143-18-9 MDL No.:MFCD11156142 MF:C9H8N2S2 MW:208.3032
4-(3-Oxopiperazin-1-yl)benzaldehyde Catalog No.:AA019RQZ CAS No.:1021240-40-3 MDL No.:MFCD11156400 MF:C11H12N2O2 MW:204.2252	(2-chlorophenyl)(2,5-dimethylphenyl)methanamine Catalog No.:AA019RY8 CAS No.:1021015-16-6 MDL No.:MFCD11149047 MF:C15H16ClN MW:245.7472
3-(2,4-Difluorophenyl)-1,2-oxazol-5-amine Catalog No.:AA019SK0 CAS No.:1021245-84-0 MDL No.:MFCD11156311 MF:C9H6F2N2O MW:196.1535	(2-chlorophenyl)(4-methoxy-2-methylphenyl)methanamine Catalog No.:AA019SPE CAS No.:1021017-56-0 MDL No.:MFCD11149166 MF:C15H16ClNO MW:261.7466
2-(2-bromo-4-methylphenoxy)pyridine-3-carbonitrile Catalog No.:AA019SYC CAS No.:1021143-01-0 MDL No.:MFCD11156083 MF:C13H9BrN2O MW:289.1274	{2-[(oxolan-2-yl)methoxy]phenyl}methanol Catalog No.:AA019TCU CAS No.:1021031-79-7 MDL No.:MFCD11149628 MF:C12H16O3 MW:208.2536
3-amino-2-[(3,5-dimethoxyphenyl)methyl]propan-1-ol Catalog No.:AA019TLO CAS No.:1020943-78-5 MDL No.:MFCD11147528 MF:C12H19NO3 MW:225.2842	2-(2-ethoxyphenoxy)benzoic acid Catalog No.:AA019TTC CAS No.:1021245-76-0 MDL No.:MFCD12553798 MF:C15H14O4 MW:258.2693
methyl 2-{[(5-chlorothiophen-2-yl)methyl]amino}acetate Catalog No.:AA019TTG CAS No.:1021000-80-5 MDL No.:MFCD11150560 MF:C8H10ClNO2S MW:219.6885	4-[(2-cyanophenyl)sulfanyl]benzoic acid Catalog No.:AA019TUC CAS No.:1021236-88-3 MDL No.:MFCD11528954 MF:C14H9NO2S MW:255.2918
2,3-dihydro-1-benzofuran-3,6-diol Catalog No.:AA019U0Y CAS No.:1020947-92-5 MDL No.:MFCD11149382 MF:C8H8O3 MW:152.1473	2-(6,7-Dihydrothieno[3,2-c]pyridin-5(4h)-yl)-2-(4-isopropylphenyl)ethanamine Catalog No.:AA019U99 CAS No.:1021233-79-3 MDL No.:MFCD11106777 MF:C18H24N2S MW:300.4616
2-chloro-6-(4-methylpiperazin-1-yl)benzaldehyde Catalog No.:AA019UU0 CAS No.:1021017-88-8 MDL No.:MFCD11156350 MF:C12H15ClN2O MW:238.7133	2-(2,6-dimethylmorpholin-4-yl)benzaldehyde Catalog No.:AA019UU2 CAS No.:1020957-43-0 MDL No.:MFCD11156355 MF:C13H17NO2 MW:219.2796
2-(3-bromophenoxy)benzoic acid Catalog No.:AA019VFK CAS No.:1021245-85-1 MDL No.:MFCD11156621 MF:C13H9BrO3 MW:293.1128	N,1-dimethyl-N-[2-(methylamino)ethyl]piperidin-4-amine Catalog No.:AA019VHK CAS No.:1020945-27-0 MDL No.:MFCD11155220 MF:C10H23N3 MW:185.3097
2-[(6-methoxypyridin-3-yl)amino]ethan-1-ol Catalog No.:AA019VS9 CAS No.:1020955-98-9 MDL No.:MFCD11149972 MF:C8H12N2O2 MW:168.1931	(prop-2-yn-1-yl)(2,2,2-trifluoroethyl)amine Catalog No.:AA019VVG CAS No.:1020931-14-9 MDL No.:MFCD11149687 MF:C5H6F3N MW:137.1030
2,4-Difluoro-n-(furan-2-ylmethyl)aniline Catalog No.:AA019VWB CAS No.:1021109-39-6 MDL No.:MFCD11145814 MF:C11H9F2NO MW:209.1921	(2-methoxyethyl)(1-methoxypropan-2-yl)amine Catalog No.:AA019W7Y CAS No.:1021042-07-8 MDL No.:MFCD11151272 MF:C7H17NO2 MW:147.2154
N-methyl-2-(propylamino)acetamide Catalog No.:AA019WA1 CAS No.:1021141-15-0 MDL No.:MFCD11154481 MF:C6H14N2O MW:130.1882	4-(4-bromophenoxy)-3-fluorobenzoic acid Catalog No.:AA019WJG CAS No.:1020999-94-3 MDL No.:MFCD11529204 MF:C13H8BrFO3 MW:311.1032
7-(pyrrolidin-1-yl)heptan-1-amine Catalog No.:AA019WMR CAS No.:1020937-83-0 MDL No.:MFCD11154919 MF:C11H24N2 MW:184.3217	2-[4-amino-3-(trifluoromethyl)phenoxy]ethan-1-ol Catalog No.:AA019WNK CAS No.:1021024-20-3 MDL No.:MFCD11136601 MF:C9H10F3NO2 MW:221.1764
3-Chloro-6-ethoxypyridine-2-carboxylic acid Catalog No.:AA019X3R CAS No.:1020945-92-9 MDL No.:MFCD11147588 MF:C8H8ClNO3 MW:201.6070	5-(4-fluoro-3-methylphenyl)-1H-1,2,3,4-tetrazole Catalog No.:AA019X7Z CAS No.:1020969-35-0 MDL No.:MFCD11155438 MF:C8H7FN4 MW:178.1664
1-(prop-2-en-1-yl)-1H-indole-3-carboxylic acid Catalog No.:AA019XAG CAS No.:1021244-66-5 MDL No.:MFCD11155405 MF:C12H11NO2 MW:201.2212	2,3-Dimethyl-n-(2,2,2-trifluoroethyl)aniline Catalog No.:AA019XG6 CAS No.:1021088-29-8 MDL No.:MFCD11154239 MF:C10H12F3N MW:203.2042
3-chloro-6-(2-methoxyethoxy)pyridine-2-carboxylic acid Catalog No.:AA019XGD CAS No.:1020947-39-0 MDL No.:MFCD11147622 MF:C9H10ClNO4 MW:231.6330	Ethyl 2-[(2,2,2-trifluoroethyl)amino]acetate Catalog No.:AA019XID CAS No.:1021002-60-7 MDL No.:MFCD11154791 MF:C6H10F3NO2 MW:185.1443
3-chloro-6-(propan-2-yloxy)pyridine-2-carboxylic acid Catalog No.:AA019XQ2 CAS No.:1021044-11-0 MDL No.:MFCD11147628 MF:C9H10ClNO3 MW:215.6336	1-amino-3-[(4-methoxyphenyl)methoxy]propan-2-ol Catalog No.:AA019XWO CAS No.:1020995-56-5 MDL No.:MFCD11147557 MF:C11H17NO3 MW:211.2576
2-[(3-methoxyphenyl)amino]-N-methylacetamide Catalog No.:AA019Y0F CAS No.:1020940-87-7 MDL No.:MFCD11154225 MF:C10H14N2O2 MW:194.2304	[2-(2-Methoxyethoxy)phenyl]methanol Catalog No.:AA019YNQ CAS No.:1020929-44-5 MDL No.:MFCD11149625 MF:C10H14O3 MW:182.2164
3-methyl-1-(morpholin-4-yl)butan-2-amine Catalog No.:AA019YZO CAS No.:1021235-04-0 MDL No.:MFCD11154922 MF:C9H20N2O MW:172.2679	1-(2,4-difluorophenyl)-2,2-dimethylpropan-1-amine Catalog No.:AA019ZKR CAS No.:1021067-85-5 MDL No.:MFCD11148445 MF:C11H15F2N MW:199.2403
1-(2,4-DIFLUOROPHENYL)-2-METHYLPROPAN-1-AMINE Catalog No.:AA019ZKS CAS No.:1021001-13-7 MDL No.:MFCD11148450 MF:C10H13F2N MW:185.2137	[(3,4-dihydro-2H-1,4-benzoxazin-2-yl)methyl]dimethylamine Catalog No.:AA019ZXB CAS No.:1021016-53-4 MDL No.:MFCD11155331 MF:C11H16N2O MW:192.2575
N-(2,2,2-trifluoroethyl)-4-(trifluoromethyl)aniline Catalog No.:AA019ZZI CAS No.:1021128-03-9 MDL No.:MFCD11152022 MF:C9H7F6N MW:243.1490	2-(Cyclopentylamino)-1-(pyrrolidin-1-yl)ethan-1-one Catalog No.:AA01A1JU CAS No.:1021131-91-8 MDL No.:MFCD11150331 MF:C11H20N2O MW:196.2893
(3-chlorophenyl)(4-ethoxyphenyl)methanamine Catalog No.:AA01A268 CAS No.:1020997-79-8 MDL No.:MFCD11148148 MF:C15H16ClNO MW:261.7466	2-[(2,4-Difluorophenyl)amino]ethan-1-ol Catalog No.:AA01A2BB CAS No.:1020993-12-7 MDL No.:MFCD11153579 MF:C8H9F2NO MW:173.1600
5-bromo-1-(2-methoxyethyl)-2,3-dihydro-1H-indole-2,3-dione Catalog No.:AA01A2QF CAS No.:1020974-19-9 MDL No.:MFCD11147953 MF:C11H10BrNO3 MW:284.1060	4-[(4-methoxyphenyl)methoxy]butanenitrile Catalog No.:AA01A2VV CAS No.:1021042-96-5 MDL No.:MFCD11147567 MF:C12H15NO2 MW:205.2530
1-(3,4-DIFLUOROPHENYL)-2-METHYLPROPAN-1-AMINE Catalog No.:AA01A37Q CAS No.:1021031-68-4 MDL No.:MFCD11148305 MF:C10H13F2N MW:185.2137	4-Chloro-6-methoxy-2,5-dimethylpyrimidine Catalog No.:AA01A3DT CAS No.:102074-10-2 MDL No.:MFCD18873554 MF:C7H9ClN2O MW:172.6122
2-Chloro-6-(dimethylamino)benzaldehyde Catalog No.:AA01A3ED CAS No.:1021240-67-4 MDL No.:MFCD11156407 MF:C9H10ClNO MW:183.6348	1-(4-Methoxyphenyl)-5-methyl-1H-pyrazole-3-carboxylic acid Catalog No.:AA01A487 CAS No.:1020724-35-9 MDL No.:MFCD08443790 MF:C12H12N2O3 MW:232.2353
[3-methoxy-4-(3-phenylpropoxy)phenyl]methanol Catalog No.:AA01A4JQ CAS No.:1021030-78-3 MDL No.:MFCD13566860 MF:C17H20O3 MW:272.3389	1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazole-3-carboxylic acid Catalog No.:AA01A4TL CAS No.:1020724-32-6 MDL No.:MFCD08443789 MF:C11H8Cl2N2O2 MW:271.0994
(2,3-dihydro-1-benzofuran-5-yl)(4-methoxyphenyl)methanamine Catalog No.:AA01A517 CAS No.:1020982-14-2 MDL No.:MFCD12738336 MF:C16H17NO2 MW:255.3117	N-(4-bromo-2,6-dimethylphenyl)-4-chlorobutanamide Catalog No.:AA01A5F1 CAS No.:1021021-78-2 MDL No.:MFCD13810323 MF:C12H15BrClNO MW:304.6106
3,3,3-Trifluoro-1-[3-(trifluoromethyl)phenyl]propan-1-amine Catalog No.:AA01A6W1 CAS No.:1020972-39-7 MDL No.:MFCD11148416 MF:C10H9F6N MW:257.1756	3-fluoro-4-(2-fluorophenoxy)benzaldehyde Catalog No.:AA01A7GF CAS No.:1021233-15-7 MDL No.:MFCD11156482 MF:C13H8F2O2 MW:234.1982
2-[(3-ethynylphenyl)amino]-1-(morpholin-4-yl)ethan-1-one Catalog No.:AA01A7IN CAS No.:1021083-28-2 MDL No.:MFCD11149855 MF:C14H16N2O2 MW:244.2890	2-[(3-ethynylphenyl)amino]-N-methylacetamide Catalog No.:AA01A7PP CAS No.:1020974-72-4 MDL No.:MFCD11149845 MF:C11H12N2O MW:188.2258
4-[Butyl(ethyl)amino]benzoic acid Catalog No.:AA01A7WX CAS No.:1020932-89-1 MDL No.:MFCD11156538 MF:C13H19NO2 MW:221.2955	2-[(4-methoxyphenyl)methoxy]acetonitrile Catalog No.:AA01A7Z9 CAS No.:1020944-81-3 MDL No.:MFCD11147566 MF:C10H11NO2 MW:177.1998
N-(1-Cyclopropylethyl)-4-methoxyaniline Catalog No.:AA01A8AU CAS No.:1020962-38-2 MDL No.:MFCD11147338 MF:C12H17NO MW:191.2695	4-methanesulfonyl-N-(propan-2-yl)aniline Catalog No.:AA01A8LQ CAS No.:1021125-82-5 MDL No.:MFCD11143921 MF:C10H15NO2S MW:213.2966
N-methyl-2-[(2-methylphenyl)amino]acetamide Catalog No.:AA01A8MJ CAS No.:1021236-82-7 MDL No.:MFCD11154387 MF:C10H14N2O MW:178.2310	2-(5-chloro-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)-N-(prop-2-yn-1-yl)acetamide Catalog No.:AA01A8ML CAS No.:1020956-98-2 MDL No.:MFCD12448422 MF:C13H9ClN2O3 MW:276.6752
3-(2,3-dihydro-1H-inden-5-yl)-1,2-oxazol-5-amine Catalog No.:AA01A8N7 CAS No.:1020955-13-8 MDL No.:MFCD11156295 MF:C12H12N2O MW:200.2365	3-(3,5-Difluorophenyl)isoxazol-5-amine Catalog No.:AA01A8MO CAS No.:1020996-82-0 MDL No.:MFCD11156290 MF:C9H6F2N2O MW:196.1535
2-{[(1-ethylpyrrolidin-2-yl)methyl]amino}-N,N-dimethylacetamide Catalog No.:AA01A8P4 CAS No.:1021241-92-8 MDL No.:MFCD13195969 MF:C11H23N3O MW:213.3198	[2-(dimethylamino)ethyl][(1-ethylpyrrolidin-2-yl)methyl]amine Catalog No.:AA01A8R1 CAS No.:1021241-95-1 MDL No.:MFCD11153901 MF:C11H25N3 MW:199.3363
3-(2,6-Difluorophenyl)-1,2-oxazol-5-amine Catalog No.:AA01A8QW CAS No.:1021245-66-8 MDL No.:MFCD11156289 MF:C9H6F2N2O MW:196.1535	3-(4-(Difluoromethoxy)phenyl)isoxazol-5-amine Catalog No.:AA01A8XL CAS No.:1020955-05-8 MDL No.:MFCD11156291 MF:C10H8F2N2O2 MW:226.1795
2-METHYL-1-[3-(TRIFLUOROMETHYL)PHENYL]PROPAN-1-AMINE Catalog No.:AA01A9GD CAS No.:1021032-89-2 MDL No.:MFCD11148421 MF:C11H14F3N MW:217.2308	3-Methyl-1-[3-(trifluoromethyl)phenyl]butan-1-amine Catalog No.:AA01A9GQ CAS No.:1020972-76-2 MDL No.:MFCD11148423 MF:C12H16F3N MW:231.2573
2,5-dimethyl-N-(propan-2-yl)aniline Catalog No.:AA01A9HW CAS No.:1021133-01-6 MDL No.:MFCD11147290 MF:C11H17N MW:163.2594	1-(6-amino-2,3-dihydro-1H-indol-1-yl)-2-(3-methoxyphenyl)ethan-1-one Catalog No.:AA01A9OJ CAS No.:1021135-13-6 MDL No.:MFCD13565433 MF:C17H18N2O2 MW:282.3370
2-(5-amino-2,3-dihydro-1H-indol-1-yl)-N,N-dimethylacetamide Catalog No.:AA01A9UH CAS No.:1021025-04-6 MDL No.:MFCD11137612 MF:C12H17N3O MW:219.2829	2-[(3-fluorophenyl)amino]-N-methylacetamide Catalog No.:AA01A9VC CAS No.:1021087-17-1 MDL No.:MFCD11152934 MF:C9H11FN2O MW:182.1948
4-(Dimethylamino)-3-fluorobenzaldehyde Catalog No.:AA01AA14 CAS No.:1021240-69-6 MDL No.:MFCD11156408 MF:C9H10FNO MW:167.1802	3-ethynyl-N-(propan-2-yl)aniline Catalog No.:AA01AACZ CAS No.:1021135-59-0 MDL No.:MFCD11138242 MF:C11H13N MW:159.2276
N-Ethyl-3-ethynylaniline Catalog No.:AA01AAGG CAS No.:1021135-66-9 MDL No.:MFCD11138254 MF:C10H11N MW:145.2010	3-(4-butoxyphenyl)-1,2-oxazol-5-amine Catalog No.:AA01AALY CAS No.:1021245-75-9 MDL No.:MFCD11156298 MF:C13H16N2O2 MW:232.2783
3-[4-(propan-2-yl)phenyl]-1,2-oxazol-5-amine Catalog No.:AA01AAVX CAS No.:1020996-98-8 MDL No.:MFCD11156296 MF:C12H14N2O MW:202.2524	(2,5-Difluorophenyl)(pyridin-4-yl)methanamine Catalog No.:AA01AB0Z CAS No.:1020994-38-0 MDL No.:MFCD11149244 MF:C12H10F2N2 MW:220.218
4-(2-bromo-4-methylphenoxy)-3-chloroaniline Catalog No.:AA01ABAO CAS No.:1021236-09-8 MDL No.:MFCD11156069 MF:C13H11BrClNO MW:312.5895	(2-amino-3-methylbutyl)(benzyl)methylamine Catalog No.:AA01ACGC CAS No.:1020941-53-0 MDL No.:MFCD11155092 MF:C13H22N2 MW:206.3272
3-(3-fluoro-4-methylphenyl)-1,2-oxazol-5-amine Catalog No.:AA01AD3V CAS No.:1020955-76-3 MDL No.:MFCD11156308 MF:C10H9FN2O MW:192.1897	1-[2-chloro-4-(4-fluorophenoxy)phenyl]ethan-1-one Catalog No.:AA01AF3D CAS No.:1021187-74-5 MDL No.:MFCD20557802 MF:C14H10ClFO2 MW:264.6794
[(2-chloro-4-fluorophenyl)methyl](2-methoxyethyl)amine Catalog No.:AA01AGFE CAS No.:1020960-15-9 MDL No.:MFCD11150172 MF:C10H13ClFNO MW:217.6677	methyl 2-(3-chloro-N-methylpropanamido)acetate Catalog No.:AA01AGMV CAS No.:1020992-22-6 MDL No.:MFCD11147823 MF:C7H12ClNO3 MW:193.6281
3-(2-Iodophenyl)isoxazol-5-amine Catalog No.:AA01AGRT CAS No.:1020955-28-5 MDL No.:MFCD11156300 MF:C9H7IN2O MW:286.0692	[2-(CYCLOPROPYLMETHOXY)PYRIDIN-4-YL]METHANAMINE Catalog No.:AA01AH02 CAS No.:1021024-16-7 MDL No.:MFCD11136582 MF:C10H14N2O MW:178.2310
4-[4-(cyanomethyl)phenoxy]benzoic acid Catalog No.:AA01AGZZ CAS No.:1021144-57-9 MDL No.:MFCD12452313 MF:C15H11NO3 MW:253.2527	1-(MORPHOLIN-4-YL)-3-PHENYLPROPAN-2-AMINE Catalog No.:AA01AH9T CAS No.:1021146-87-1 MDL No.:MFCD30749430 MF:C13H20N2O MW:220.3107
[3-(2,2,2-Trifluoroethoxy)phenyl]methanol Catalog No.:AA01AHC1 CAS No.:1021063-95-5 MDL No.:MFCD11149514 MF:C9H9F3O2 MW:206.1618	Methyl 2-([2-(dimethylamino)ethyl]amino)acetate Catalog No.:AA01AHF1 CAS No.:1020932-71-1 MDL No.:MFCD11154725 MF:C7H16N2O2 MW:160.2141
2-[methyl(propan-2-yl)amino]benzoic acid Catalog No.:AA01AHIJ CAS No.:1021244-13-2 MDL No.:MFCD11156542 MF:C11H15NO2 MW:193.2423	N-(4-Chlorophenyl)-2-(propylamino)acetamide Catalog No.:AA01AHM1 CAS No.:1021230-54-5 MDL No.:MFCD11154493 MF:C11H15ClN2O MW:226.7026
2-[(dimethylamino)methyl]-4-methylaniline Catalog No.:AA01AI26 CAS No.:1021144-66-0 MDL No.:MFCD11156628 MF:C10H16N2 MW:164.2474	2-(piperidin-3-yloxy)ethan-1-ol Catalog No.:AA01AIL8 CAS No.:1020971-19-0 MDL No.:MFCD11147873 MF:C7H15NO2 MW:145.1995
4-(2,2,2-Trifluoroethoxy)benzenemethanol Catalog No.:AA01AJCR CAS No.:1020949-12-5 MDL No.:MFCD11149443 MF:C9H9F3O2 MW:206.1618	dimethyl[2-(piperidin-3-yloxy)ethyl]amine Catalog No.:AA01AJCW CAS No.:1020943-38-7 MDL No.:MFCD11147511 MF:C9H20N2O MW:172.2679
Methyl 2-([2-(2,4-dichlorophenyl)ethyl]amino)acetate Catalog No.:AA01AJKW CAS No.:1021120-19-3 MDL No.:MFCD11152574 MF:C11H13Cl2NO2 MW:262.1324	methyl 2-[(cyanomethyl)amino]acetate Catalog No.:AA01AJRO CAS No.:1021072-87-6 MDL No.:MFCD11150527 MF:C5H8N2O2 MW:128.1292
2-(5-fluoro-2-methylphenyl)-1H-1,3-benzodiazole Catalog No.:AA01AJTU CAS No.:1021397-45-4 MDL No.:MFCD17619241 MF:C14H11FN2 MW:226.2489	(2-chlorophenyl)(4-ethylphenyl)methanamine Catalog No.:AA01AK4H CAS No.:1021126-49-7 MDL No.:MFCD11148355 MF:C15H16ClN MW:245.7472
3-bromo-N-cyclohexylaniline Catalog No.:AA01AK7N CAS No.:1020930-79-3 MDL No.:MFCD11145020 MF:C12H16BrN MW:254.1661	6-bromo-3-hydroxy-2,3-dihydro-1H-indol-2-one Catalog No.:AA01AKVF CAS No.:1021021-75-9 MDL No.:MFCD11149373 MF:C8H6BrNO2 MW:228.0427
3,4-dimethoxy-N-(2-methoxyethyl)aniline Catalog No.:AA01AKXV CAS No.:1021000-38-3 MDL No.:MFCD11151969 MF:C11H17NO3 MW:211.2576	rac-[(1R,3S)-3-aminocyclopentyl]methanol Catalog No.:AA01ANEB CAS No.:102099-18-3 MDL No.:MFCD29034274 MF:C6H13NO MW:115.1735
methyl 2-amino-6-propyl-4H,5H,6H,7H-thieno[2,3-c]pyridine-3-carboxylate Catalog No.:AA01AQ23 CAS No.:1021014-97-0 MDL No.:MFCD03034028 MF:C12H18N2O2S MW:254.3485	6-bromo-5,7-dimethyl-1,8-naphthyridin-2-ol Catalog No.:AA01ARBE CAS No.:1021089-01-9 MDL No.:MFCD09863854 MF:C10H9BrN2O MW:253.0953
3-Bromo-7-chloro-2,4-dimethyl-1,8-naphthyridine Catalog No.:AA01ARBF CAS No.:1021117-08-7 MDL No.:MFCD09863855 MF:C10H8BrClN2 MW:271.5409	2-{3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3,8-triazaspiro[4.5]decan-8-yl}acetic acid Catalog No.:AA01ARD6 CAS No.:1021117-39-4 MDL No.:MFCD09965538 MF:C16H18FN3O4 MW:335.3302
2-(aminomethyl)-N-methyl-N-(propan-2-yl)aniline Catalog No.:AA01AUWI CAS No.:1020969-82-7 MDL No.:MFCD11155587 MF:C11H18N2 MW:178.2740	N-phenylthiolan-3-amine Catalog No.:AA01AXJ1 CAS No.:1021107-88-9 MDL No.:MFCD11138665 MF:C10H13NS MW:179.2819
(1-Cyclopropylethyl)(1-phenylethyl)amine Catalog No.:AA01AXIY CAS No.:1021076-37-8 MDL No.:MFCD11138530 MF:C13H19N MW:189.2967	ethyl 4-[(2-hydroxyethyl)amino]piperidine-1-carboxylate Catalog No.:AA01AY3F CAS No.:1021246-92-3 MDL No.:MFCD11154428 MF:C10H20N2O3 MW:216.2774
1-methyl-N-(2-methylphenyl)piperidin-4-amine Catalog No.:AA01AY2A CAS No.:1020964-10-6 MDL No.:MFCD11147368 MF:C13H20N2 MW:204.3113	2-[(cyclopropylmethyl)amino]-N,N-dimethylacetamide Catalog No.:AA01AY2X CAS No.:1021038-48-1 MDL No.:MFCD11150453 MF:C8H16N2O MW:156.2254
2,4-Dimethyl-N-(2-methylpropyl)aniline Catalog No.:AA01AXIR CAS No.:1021107-02-7 MDL No.:MFCD11138373 MF:C12H19N MW:177.2860	Ethyl 1-methyl-1H-1,2,4-triazole-3-carboxylate Catalog No.:AA01B4X6 CAS No.:102139-12-8 MDL No.:MFCD18344485 MF:C6H9N3O2 MW:155.1546
2-{[2-(dimethylamino)ethyl]amino}-N,N-dimethylacetamide Catalog No.:AA01B5GG CAS No.:1020931-43-4 MDL No.:MFCD11154676 MF:C8H19N3O MW:173.256	2-bromospiro[3.3]heptane Catalog No.:AA01B5PM CAS No.:102115-82-2 MDL No.:MFCD20633948 MF:C7H11Br MW:175.0662
6-Amino-1-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione Catalog No.:AA01B6BN CAS No.:1021143-59-8 MDL No.:MFCD11156264 MF:C6H6F3N3O2 MW:209.1259	1-[(Pyridin-4-yl)methyl]-1H-indole-2-carboxylic acid Catalog No.:AA01B6HA CAS No.:1020968-56-2 MDL No.:MFCD12626762 MF:C15H12N2O2 MW:252.268
N-(2-methoxy-5-methylphenyl)-2-methyl-6-phenylpyrimidin-4-amine Catalog No.:AA01B83P CAS No.:1021281-75-3 MDL No.:MFCD09982346 MF:C19H19N3O MW:305.3737	[3-(2-methylpropoxy)phenyl]methanol Catalog No.:AA01B940 CAS No.:1021064-15-2 MDL No.:MFCD11149531 MF:C11H16O2 MW:180.2435
[(2-Chloro-4-fluorophenyl)methyl](cyclopropylmethyl)amine Catalog No.:AA01BA9P CAS No.:1020979-51-4 MDL No.:MFCD11150464 MF:C11H13ClFN MW:213.6790	imidazo[1,2-a]pyridin-2-yl trifluoromethanesulfonate Catalog No.:AA01BARR CAS No.:1021019-74-8 MDL No.:MFCD25954306 MF:C8H5F3N2O3S MW:266.1971
N-(3-methylphenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine Catalog No.:AA01BB3V CAS No.:1021262-22-5 MDL No.:MFCD11993831 MF:C21H21N3O2 MW:347.4103	1-(3-Cyanopropyl)-1H-indole-3-carboxylic acid Catalog No.:AA01BE2I CAS No.:1020984-72-8 MDL No.:MFCD11155410 MF:C13H12N2O2 MW:228.2466
2-amino-5-bromo-3-fluorobenzene-1-thiol Catalog No.:AA01BEFF CAS No.:1020745-85-0 MDL No.:MFCD17168579 MF:C6H5BrFNS MW:222.0780	3-{[(naphthalen-1-yl)amino]methyl}phenol Catalog No.:AA01BEKR CAS No.:1021091-90-6 MDL No.:MFCD12623404 MF:C17H15NO MW:249.3071
6-amino-2,3-dihydro-1H-indole-1-carboxamide Catalog No.:AA01BFIS CAS No.:1021135-29-4 MDL No.:MFCD11137593 MF:C9H11N3O MW:177.2031	4-[(pyridin-4-yl)methyl]piperidin-4-ol dihydrochloride Catalog No.:AA01BGDS CAS No.:1021205-22-0 MDL No.:MFCD28010457 MF:C11H18Cl2N2O MW:265.1794
4-(Pyridin-3-ylmethyl)piperidin-4-ol dihydrochloride Catalog No.:AA01BGIA CAS No.:1021205-21-9 MDL No.:MFCD28125175 MF:C11H18Cl2N2O MW:265.1794	2-{[4-(trifluoromethyl)phenyl]amino}ethan-1-ol Catalog No.:AA01BIJ2 CAS No.:1021003-12-2 MDL No.:MFCD11152038 MF:C9H10F3NO MW:205.1770
2-(Bromomethyl)spiro[3.3]heptane Catalog No.:AA01BKRO CAS No.:102115-83-3 MDL No.:MFCD20633953 MF:C8H13Br MW:189.0928	5-methyl-1-[4-(propan-2-yl)phenyl]-1H-pyrazole-3-carboxylic acid Catalog No.:AA01BV6K CAS No.:1020724-11-1 MDL No.:MFCD08443779 MF:C14H16N2O2 MW:244.2890
2-[(4-fluoro-2-methylphenyl)amino]acetonitrile Catalog No.:AA01BVIT CAS No.:1021233-24-8 MDL No.:MFCD11153945 MF:C9H9FN2 MW:164.1796	2-fluoro-N-[2-(morpholin-4-yl)ethyl]aniline Catalog No.:AA01BXFR CAS No.:1021133-89-0 MDL No.:MFCD11153388 MF:C12H17FN2O MW:224.2746
N-(2-methoxyethyl)-4-(methylsulfanyl)aniline Catalog No.:AA01BXS9 CAS No.:1020995-38-3 MDL No.:MFCD11151609 MF:C10H15NOS MW:197.2972	2,5-dichloro-N-(2-methoxyethyl)aniline Catalog No.:AA01C01A CAS No.:1021004-84-1 MDL No.:MFCD11150716 MF:C9H11Cl2NO MW:220.0957
3,5-dichloro-N-(2-methoxyethyl)aniline Catalog No.:AA01C05P CAS No.:1020955-00-3 MDL No.:MFCD11152127 MF:C9H11Cl2NO MW:220.0957	4-(2,6-dimethylmorpholin-4-yl)benzoic acid Catalog No.:AA01C07U CAS No.:1021243-39-9 MDL No.:MFCD11156519 MF:C13H17NO3 MW:235.2790
Methyl 4-bromo-2-iodo-6-methylbenzoate Catalog No.:AA01C2LM CAS No.:1021344-69-3 MDL No.:MFCD09260951 MF:C9H8BrIO2 MW:354.9671	2-[(3,4-difluorophenyl)amino]ethan-1-ol Catalog No.:AA01C3YM CAS No.:1021136-84-4 MDL No.:MFCD11152762 MF:C8H9F2NO MW:173.16
3-[(tert-butoxy)carbonyl]cyclohexane-1-carboxylic acid Catalog No.:AA01C4LS CAS No.:1020965-27-8 MDL No.:MFCD22416341 MF:C12H20O4 MW:228.2848	Pentanoic acid, 2-amino-4,4-dimethyl-, methyl ester Catalog No.:AA01C4ML CAS No.:1021417-79-7 MDL No.:MFCD09919972 MF:C8H17NO2 MW:159.2261
Methyl 2-amino-4,4-dimethylpentanoate hydrochloride Catalog No.:AA01C4MK CAS No.:1021392-21-1 MDL No.:MFCD28895661 MF:C8H18ClNO2 MW:195.6870	5-amino-1-(2-hydroxyethyl)-1,2-dihydropyridin-2-one Catalog No.:AA01C52Z CAS No.:1021047-93-7 MDL No.:MFCD11147852 MF:C7H10N2O2 MW:154.1665
2,6-Dimethylaniline-d9 Catalog No.:AA01CBVN CAS No.:1021325-45-0 MDL No.: MF:C8H2D9N MW:130.2351	2,4,5,6-Tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-1H-benz[de]isoquinolin-1-one Catalog No.:AA01CBWQ CAS No.:1021456-82-5 MDL No.: MF:C19H22N2O2 MW:310.3902
Sulfamerazine-d4 Catalog No.:AA01CCH2 CAS No.:1020719-84-9 MDL No.:MFCD03425631 MF:C11H8D4N4O2S MW:268.3282	Sulfathiazole-d4 Catalog No.:AA01CCHE CAS No.:1020719-89-4 MDL No.:MFCD03425633 MF:C9H5D4N3O2S2 MW:259.3413
Triclosan-methyl-d3 Catalog No.:AA01CCL6 CAS No.:1020720-00-6 MDL No.:MFCD04039701 MF:C13H6Cl3D3O2 MW:306.5868	4-(1-Methyl-1H-tetrazol-5-yl)piperidine hydrochloride Catalog No.:AA01DMHB CAS No.:1020748-26-8 MDL No.:MFCD26407003 MF:C7H14ClN5 MW:203.6726
({imidazo[1,2-a]pyridin-2-yl}methyl)(2,2,2-trifluoroethyl)amine Catalog No.:AA01DT9M CAS No.:1020933-75-8 MDL No.:MFCD11154779 MF:C10H10F3N3 MW:229.2017	2-[4-(1-aminoethyl)-2-methoxyphenoxy]ethan-1-ol Catalog No.:AA01DU91 CAS No.:1020992-57-7 MDL No.:MFCD11147849 MF:C11H17NO3 MW:211.2576
2-[(4-methylcyclohexyl)oxy]benzaldehyde Catalog No.:AA01DX4C CAS No.:1020960-74-0 MDL No.:MFCD11156467 MF:C14H18O2 MW:218.2915	2,5-Dimethylpiperidin-4-one Hydrochloride Catalog No.:AA01DX4B CAS No.:102074-04-4 MDL No.:MFCD31616164 MF:C7H14ClNO MW:163.6452
(3-chlorophenyl)[3-(trifluoromethyl)phenyl]methanamine Catalog No.:AA01DX4D CAS No.:1021127-59-2 MDL No.:MFCD13272825 MF:C14H11ClF3N MW:285.692	2-(Nonylthio)propanamide Catalog No.:AA01DZA2 CAS No.:1021343-21-4 MDL No.: MF:C6H10O2 MW:114.1424
2,6-Dimethylphenol-d9 (Major) Catalog No.:AA01DZA1 CAS No.:1021325-40-5 MDL No.: MF:C8HD9O MW:131.2199	4-Amino-3,5-dibromo-b-[(1,1-dimethylethyl)amino]benzeneethanol Hydrochloride Catalog No.:AA01DZA0 CAS No.:1021154-79-9 MDL No.: MF:C12H19Br2ClN2O MW:402.5531
(2-Methoxyethyl)(prop-2-yn-1-yl)amine Catalog No.:AA01E5ZH CAS No.:1020931-60-5 MDL No.:MFCD11149713 MF:C6H11NO MW:113.1576	2-(3-fluorophenoxy)benzaldehyde Catalog No.:AA01E5ZG CAS No.:1020931-53-6 MDL No.:MFCD11156495 MF:C13H9FO2 MW:216.2078
1-[(dimethylcarbamoyl)methyl]-1H-indole-2-carboxylic acid Catalog No.:AA01E8KU CAS No.:1021142-22-2 MDL No.:MFCD11528945 MF:C13H14N2O3 MW:246.2619	2-(2-bromo-4-chlorophenoxy)benzaldehyde Catalog No.:AA01E8LQ CAS No.:1021242-85-2 MDL No.:MFCD11156497 MF:C13H8BrClO2 MW:311.5584
4-[[2-[(4-Bromophenyl)thio]acetyl]amino]-1-(2-phenylethyl)-1H-pyrazole-3-carboxylic acid Catalog No.:AA01EH5A CAS No.:1021497-97-1 MDL No.:MFCD30738005 MF:C20H18BrN3O3S MW:460.3442	3-fluoro-N-({imidazo[1,2-a]pyridin-2-yl}methyl)-4-methylaniline Catalog No.:AA01EHSE CAS No.:1020955-83-2 MDL No.:MFCD12626556 MF:C15H14FN3 MW:255.2902
4-{[(1,3-dioxaindan-5-yl)amino]methyl}benzamide Catalog No.:AA01EHT7 CAS No.:1020956-33-5 MDL No.:MFCD12553669 MF:C15H14N2O3 MW:270.2833	methyl 2-(2-chloroacetamido)-3-methylpentanoate Catalog No.:AA01ELQP CAS No.:102115-69-5 MDL No.:MFCD00548262 MF:C9H16ClNO3 MW:221.6812
2-(Pyridin-3-yl)quinuclidine dihydrochloride Catalog No.:AA01ENOJ CAS No.:1021418-53-0 MDL No.: MF:C12H17ClN2 MW:224.7298	1-Bromo-3-[(2-methoxyethyl)thio]-benzene Catalog No.:AA01EQIZ CAS No.:1021169-59-4 MDL No.:MFCD26142715 MF:C9H11BrOS MW:247.152
2-(3-Bromobenzenesulfonyl)ethan-1-ol Catalog No.:AA01FD7U CAS No.:1021169-75-4 MDL No.:MFCD25954312 MF:C8H9BrO3S MW:265.1243	1-Methyl-1-(4-trifluoromethylphenyl)ethylamine Catalog No.:AA00H9NY CAS No.:1020920-65-3 MDL No.:MFCD09258816 MF:C10H12F3N MW:203.2042
1,2,3,6-Tetrahydrophthalimide-3,3,4,5,6,6-d6 Catalog No.:AA0006HF CAS No.:1020719-96-3 MDL No.:MFCD03425637 MF:C8H3D6NO2 MW:157.1995	4-Bromoquinoline-8-carbonitrile Catalog No.:AA0006HW CAS No.:1020743-28-5 MDL No.:MFCD08063212 MF:C10H5BrN2 MW:233.0641
5-(Dicyclohexylphosphino)-1',3',5'-triphenyl-[1,4']-bi-1H-pyrazole Catalog No.:AA0006KN CAS No.:1021176-69-1 MDL No.:MFCD11616511 MF:C36H39N4P MW:558.6954	Diethyl 2-((2-cyanovinyl)amino)malonate Catalog No.:AA0006KO CAS No.:1021175-71-2 MDL No.:MFCD19441867 MF:C10H14N2O4 MW:226.2292
Trifluoro-methanesulfonic acid 2-methoxy-4-formyl-6-nitro-phenyl ester Catalog No.:AA0006O3 CAS No.:1021493-52-6 MDL No.:MFCD19441864 MF:C9H6F3NO7S MW:329.2066	2-chloro-6-[(3-methoxyphenyl)methoxy]benzaldehyde Catalog No.:AA019VVV CAS No.:1021241-46-2 MDL No.:MFCD12165967 MF:C15H13ClO3 MW:276.7149