Name: Name:S-23
Brand: AABLOCKS
SKU: AA0094XQ
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0094XQ

Chemical Name: S-23

CAS Number: 1010396-29-8

Molecular Formula: C18H13ClF4N2O3

Molecular Weight: 416.7540

MDL Number: MFCD24849232

SMILES: N#Cc1ccc(cc1C(F)(F)F)NC(=O)[C@](COc1ccc(c(c1)F)Cl)(O)C

Properties

Complexity: 611

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 28

Hydrogen Bond Acceptor Count: 8

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 5

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 3.7

Downstream Synthesis Route

654-70-6

1010396-29-8

[1]Patent:US2016/106702,2016,A1

Literature fold

Title: Characterization of in vitro generated metabolites of the selective androgen receptor modulators S-22 and S-23 and in vivo comparison to post-administration canine urine specimens.

Journal: Drug testing and analysis20100101

Title: Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit.

Journal: Journal of medicinal chemistry20090625

Title: Preclinical characterization of a (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide: a selective androgen receptor modulator for hormonal male contraception.

Journal: Endocrinology20090101

Title: Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators.

Journal: Bioorganic & medicinal chemistry letters20081015

Title: Jones A, et al. Preclinical characterization of a (S)-N-(4-cyano-3-trifluoromethyl-phenyl)-3-(3-fluoro, 4-chlorophenoxy)-2-hydroxy-2-methyl-propanamide: a selective androgen receptor modulator for hormonal male contraception. Endocrinology. 2009;150(1):385-395.

Title: Thevis M, et al. Characterization of in vitro generated metabolites of the selective androgen receptor modulators S-22 and S-23 and in vivo comparison to post-administration canine urine specimens. Drug Test Anal. 2010;2(11-12):589-598.

1010396-29-8 | S-23