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1021868-83-6,MFCD08544552
Catalog No.:AA01DZA5

1021868-83-6 | ARL67156TrisodiumSalt

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1mg
99%
1 week  
$336.00   $235.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DZA5
Chemical Name:
ARL67156TrisodiumSalt
CAS Number:
1021868-83-6
Molecular Formula:
C15H21Br2N5Na3O12P3
Molecular Weight:
785.0521
MDL Number:
MFCD08544552
SMILES:
CCN(c1ncnc2c1ncn2[C@@H]1O[C@@H]([C@H]([C@@H]1O)O)COP(=O)(OP(=O)(C(P(=O)(O[Na])O)(Br)Br)O[Na])O[Na])CC
Properties
Computed Properties
 
Complexity:
981  
Covalently-Bonded Unit Count:
4  
Defined Atom Stereocenter Count:
4  
Heavy Atom Count:
40  
Hydrogen Bond Acceptor Count:
16  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
11  

Literature

Title: Lévesque SA, et al. Specificity of the ecto-ATPase inhibitor ARL 67156 on human and mouse ectonucleotidases. Br J Pharmacol. 2007 Sep;152(1):141-50.

Title: Nancy Côté, et al. Inhibition of Ectonucleotidase With ARL67156 Prevents the Development of Calcific Aortic Valve Disease in Warfarin-Treated Rats. Eur J Pharmacol. 2012 Aug 15;689(1-3):139-46.

Title: Flávio P Veras, et al. Fructose 1,6-bisphosphate, a high-energy intermediate of glycolysis, attenuates experimental arthritis by activating anti-inflammatory adenosinergic pathway. Sci Rep. 2015 Oct 19;5:15171.

Title: C Kennedy, et al. ATP as a co-transmitter with noradrenaline in sympathetic nerves--function and fate. Ciba Found Symp. 1996;198:223-35; discussion 235-8.

Title: Ya-Dong Gao, et al. Th2 cytokine-primed airway smooth muscle cells induce mast cell chemotaxis via secretion of ATP. J Asthma. 2014 Dec;51(10):997-1003.

Title: Casilde Sesti, et al. EctoNucleotidase in cardiac sympathetic nerve endings modulates ATP-mediated feedback of norepinephrine release. J Pharmacol Exp Ther. 2002 Feb;300(2):605-11.

Title: Julieta Schachter, et al. Inhibition of ecto-ATPase activities impairs HIV-1 infection of macrophages. Immunobiology. 2015 May;220(5):589-96.

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Tags:1021868-83-6 Molecular Formula|1021868-83-6 MDL|1021868-83-6 SMILES|1021868-83-6 ARL67156TrisodiumSalt