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1022152-70-0,MFCD18782708
Catalog No.:AA008TJT

1022152-70-0 | MK-5046

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5mg
≥99%
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$445.00   $312.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008TJT
Chemical Name:
MK-5046
CAS Number:
1022152-70-0
Molecular Formula:
C20H18F6N4O
Molecular Weight:
444.3735
MDL Number:
MFCD18782708
SMILES:
FC([C@@](c1ccc(cc1)n1cccn1)(Cc1[nH]cc(n1)CC1(CC1)C(F)(F)F)O)(F)F
Properties
Computed Properties
 
Complexity:
632  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
4.1  

Literature

Title: Guan XM, et al. Antiobesity effect of MK-5046, a novel bombesin receptor subtype-3 agonist. J Pharmacol Exp Ther. 2011 Feb;336(2):356-364.

Title: Sebhat IK, et al. Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity. ACS Med Chem Lett. 2010 Oct 18;2(1):43-47.

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SDS
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