Title: Identification of N-(4-((1R,3S,5S)-3-Amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies.
Journal: Journal of medicinal chemistry 20151112
Title: Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors.
Journal: ACS medicinal chemistry letters 20131212
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma.
Journal: Blood 20121025
Title: Potential use of selective and nonselective Pim kinase inhibitors for cancer therapy.
Journal: Journal of medicinal chemistry 20121011
Title: Targeting PIM kinase activity significantly augments the efficacy of cytarabine.
Journal: British journal of haematology 20120101
Title: The Pim kinases: new targets for drug development.
Journal: Current drug targets 20111201
Title: PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells.
Journal: Oncotarget 20111201
Title: Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma.
Journal: British journal of cancer 20111108
Title: Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia.
Journal: Blood 20110721
Title: Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells.
Journal: Blood 20091105
Title: Pharmacologic inhibition of Pim kinases alters prostate cancer cell growth and resensitizes chemoresistant cells to taxanes.
Journal: Molecular cancer therapeutics 20091001
1135283-37-2 | Methyl 2-(6-chloro-8-iodoimidazo[1,2-a]pyridin-2-yl)acetate | AA0008U7 | MFCD11840999
1138324-48-7 | (2S,4R)-1-(tert-Butoxycarbonyl)-4-fluoro-2-hydroxymethylpyrrolidine | AA0009R7 | MFCD22573266
114102-89-5 | (2S,3R,4S,5R,6R)-2-(2-Nitrophenoxy)-6-((trityloxy)methyl)tetrahydro-2H-pyran-3,4,5-triol | AA000AI3 | MFCD03701222