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103-81-1,MFCD18449377
Catalog No.:AA00327C

103-81-1 | 2-Phenylacetamide

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5g
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25g
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100g
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500g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00327C
Chemical Name:
2-Phenylacetamide
CAS Number:
103-81-1
Molecular Formula:
C8H9NO
Molecular Weight:
135.1632
MDL Number:
MFCD18449377
SMILES:
NC(=O)Cc1ccccc1
NSC Number:
1877
Properties
Properties
 
BP:
312.2 °C at 760 mmHg  
Form:
Solid  
MP:
156 °C  
Refractive Index:
1.5589 (estimate)  
Solubility:
Soluble in methanol.  
Storage:
2-8℃;Keep in dry area;  

Computed Properties
 
Complexity:
116  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
0.5  

Literature

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Journal: PloS one 20120101

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Journal: Journal of pharmaceutical and biomedical analysis 20101102

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Title: Structural characterization of the Hepatitis C Virus NS3 protease from genotype 3a: the basis of the genotype 1b vs. 3a inhibitor potency shift.

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Journal: Acta crystallographica. Section E, Structure reports online 20100101

Title: Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB.

Journal: Bioorganic & medicinal chemistry 20090715

Title: Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20090615

Title: N-(3,4-Diethoxy-phen-yl)acetamide.

Journal: Acta crystallographica. Section E, Structure reports online 20090601

Title: Utility of MetaSite in improving metabolic stability of the neutral indomethacin amide derivative and selective cyclooxygenase-2 inhibitor 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-N-phenethyl-acetamide.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090501

Title: Phenylethylamide and phenylmethylamide derivatives as new tyrosinase inhibitors.

Journal: Biological & pharmaceutical bulletin 20090201

Title: Regulation of phenylacetic acid degradation genes of Burkholderia cenocepacia K56-2.

Journal: BMC microbiology 20090101

Title: Novel inhibitors of the v-raf murine sarcoma viral oncogene homologue B1 (BRAF) based on a 2,6-disubstituted pyrazine scaffold.

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Title: Linear and cyclic peptides from the entomopathogenic bacterium Xenorhabdus nematophilus.

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Journal: SAR and QSAR in environmental research 20080101

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Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101

Title: 2,2-Dichloro-N-(2,3-dimethyl-phen-yl)acetamide.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

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Journal: Biotechnology letters 20071201

Title: Diastereospecific photocyclization of a isopropylbenzophenone derivative in crystals and the morphological changes.

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Journal: Bioorganic & medicinal chemistry 20070301

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Journal: European journal of medicinal chemistry 20060301

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Title: Inhibition of cyclooxygenase with indomethacin phenethylamide reduces atherosclerosis in apoE-null mice.

Journal: Biochemical pharmacology 20050801

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Journal: Bioorganic & medicinal chemistry letters 20040906

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Journal: Bioorganic & medicinal chemistry letters 20040705

Title: Mandelamide hydrolase from Pseudomonas putida: characterization of a new member of the amidase signature family.

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Title: Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.

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Title: Metabolism of 2-phenylethylamine to phenylacetic acid, via the intermediate phenylacetaldehyde, by freshly prepared and cryopreserved guinea pig liver slices.

Journal: In vivo (Athens, Greece) 20040101

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Title: A chemostat culture as a tool for the improvement of a recombinant E. coli strain over-producing penicillin G acylase.

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Title: An enzyme-labile safety catch linker for synthesis on a soluble polymeric support.

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Title: Substitutions of Thr-103-Ile and Trp-138-Gly in amidase from Pseudomonas aeruginosa are responsible for altered kinetic properties and enzyme instability.

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