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Home Other Building Blocks 103129-82-4
103129-82-4,MFCD09832686
Catalog No.:AA00324Y

103129-82-4 | (S)-Amlodipine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
97%
in stock  
$13.00   $9.00
- +
5g
97%
in stock  
$45.00   $32.00
- +
25g
97%
in stock  
$195.00   $137.00
- +
100g
97%
in stock  
$577.00   $404.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00324Y
Chemical Name:
(S)-Amlodipine
CAS Number:
103129-82-4
Molecular Formula:
C20H25ClN2O5
Molecular Weight:
408.8759
MDL Number:
MFCD09832686
SMILES:
NCCOCC1=C(C(=O)OCC)[C@H](C(=C(N1)C)C(=O)OC)c1ccccc1Cl
Properties
Properties
 
BP:
527.161°C at 760 mmHg  
Form:
Solid  
MP:
102-104°C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
647  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
10  
XLogP3:
3  

Downstream Synthesis Route

[1]Goldmann;Stoltefuss;Born[JournalofMedicinalChemistry,1992,vol.35,#18,p.3341-3344]

[1]Arrowsmith;Campbell;Cross;Stubbs;Burges;Gardiner;Blackburn[JournalofMedicinalChemistry,1986,vol.29,#9,p.1696-1702]

[2]Goldmann;Stoltefuss;Born[JournalofMedicinalChemistry,1992,vol.35,#18,p.3341-3344]

[1]Goldmann;Stoltefuss;Born[JournalofMedicinalChemistry,1992,vol.35,#18,p.3341-3344]

S-(-)-amlodipine-hemi-D-tartratemono-dimethylsulfoxidesolvate 
  103129-82-4 

[1]CurrentPatentAssignee:HANMIPHARMCOLTD-WO2008/10659,2008,A1Locationinpatent:Page/Pagecolumn7

3144-16-9    103129-82-4   
(S)-amlodipine(1S)-(+)-10-camsylatehydrate 

[1]CurrentPatentAssignee:HANMIPHARMCOLTD-WO2008/10659,2008,A1Locationinpatent:Page/Pagecolumn7-8

Literature

Title: Synergic effects of levamlodipine and bisoprolol on blood pressure reduction and organ protection in spontaneously hypertensive rats.

Journal: CNS neuroscience & therapeutics 20120601

Title: Affinity and specificity of levamlodipine-human serum albumin interactions: insights into its carrier function.

Journal: Biophysical journal 20090520

Title: Jain R, et al. Polyaniline-graphene oxide nanocomposite sensor for quantification of calcium channel blocker levamlodipine. Mater Sci Eng C Mater Biol Appl. 2016 Aug 1;65:205-14.

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SDS
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