+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Amines 1032568-63-0
1032568-63-0,MFCD18633201
Catalog No.:AA0039IF

1032568-63-0 | 2-Amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-5-pyrimidinecarboxamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
in stock  
$25.00   $18.00
- +
100mg
98%
in stock  
$159.00   $111.00
- +
250mg
98%
in stock  
$255.00   $178.00
- +
1g
98%
in stock  
$697.00   $488.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0039IF
Chemical Name:
2-Amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-5-pyrimidinecarboxamide
CAS Number:
1032568-63-0
Molecular Formula:
C23H28N8O4
Molecular Weight:
480.5196
MDL Number:
MFCD18633201
SMILES:
COc1c(OCCCN2CCOCC2)ccc2c1nc(NC(=O)c1cnc(nc1)N)n1c2=NCC1
Properties
Computed Properties
 
Complexity:
974  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
XLogP3:
0.3  

Literature

Title: First-in-human phase I study of copanlisib (BAY 80-6946), an intravenous pan-class I phosphatidylinositol 3-kinase inhibitor, in patients with advanced solid tumors and non-Hodgkin's lymphomas.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20161001

Title: Preliminary results of a phase II study of single agent Bay 80-6946, a Novel PI3K inhibitor, in patients with relapsed/refractory, indolent or aggressive lymphoma.

Journal: Clinical advances in hematology & oncology : H&O 20140201

Title: BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models.

Journal: Molecular cancer therapeutics 20131101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1032568-63-0
1402152-13-9

1402152-13-9

 1375469-38-7

1375469-38-7

 1032570-74-3

1032570-74-3

 1402152-13-9

1402152-13-9
Building Blocks
More >
Tags:1032568-63-0 Molecular Formula|1032568-63-0 MDL|1032568-63-0 SMILES|1032568-63-0 2-Amino-N-[2,3-dihydro-7-methoxy-8-[3-(4-morpholinyl)propoxy]imidazo[1,2-c]quinazolin-5-yl]-5-pyrimidinecarboxamide