Home Pyridines 10338-69-9
10338-69-9,MFCD00023118
Catalog No.:AA0085OA

10338-69-9 | 1,2,3,6-Tetrahydro-4-phenyl-pyridine

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100mg
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$138.00   $96.00
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250mg
98%
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$260.00   $182.00
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1g
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$505.00   $353.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0085OA
Chemical Name:
1,2,3,6-Tetrahydro-4-phenyl-pyridine
CAS Number:
10338-69-9
Molecular Formula:
C11H13N
Molecular Weight:
159.2276
MDL Number:
MFCD00023118
SMILES:
N1CCC(=CC1)c1ccccc1
NSC Number:
54451
Properties
Computed Properties
 
Complexity:
166  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
2  

Literature

Title: The role of thioredoxin-1 in suppression of endoplasmic reticulum stress in Parkinson disease.

Journal: Free radical biology & medicine 20140201

Title: Moderate chemical modifications of WAY-100635 improve the selectivity for 5-HT1A versus D4 receptors.

Journal: Bioorganic & medicinal chemistry letters 20120715

Title: L-Dihydroxyphenylalanine modulates the steady-state expression of mouse striatal tyrosine hydroxylase, aromatic L-amino acid decarboxylase, dopamine and its metabolites in an MPTP mouse model of Parkinson's disease.

Journal: Life sciences 20111024

Title: Polygalae radix inhibits toxin-induced neuronal death in the Parkinson's disease models.

Journal: Journal of ethnopharmacology 20110324

Title: 6-Hydroxydopamine-induced PC12 cell death is mediated by MEF2D down-regulation.

Journal: Neurochemical research 20110201

Title: Protective effects of Chunghyuldan against ROS-mediated neuronal cell death in models of Parkinson's disease.

Journal: Basic & clinical pharmacology & toxicology 20101201

Title: Neuroprotective effects of an herbal medicine, Yi-Gan San on MPP+/MPTP-induced cytotoxicity in vitro and in vivo.

Journal: Journal of ethnopharmacology 20100915

Title: Molecular modeling study of 4-phenylpiperazine and 4-phenyl-1,2,3,6-tetrahydropyridine derivatives: a new step towards the design of high-affinity 5-HT1A ligands.

Journal: Bioorganic & medicinal chemistry letters 20100201

Title: Cortical serotonin and norepinephrine denervation in parkinsonism: preferential loss of the beaded serotonin innervation.

Journal: The European journal of neuroscience 20090701

Title: Zocor Forte (simvastatin) has a neuroprotective effect against LPS striatal dopaminergic terminals injury, whereas against MPP+ does not.

Journal: European journal of pharmacology 20090501

Title: Pyrethroid and organophosphate insecticide exposure in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease: an immunohistochemical analysis of tyrosine hydroxylase and glial fibrillary acidic protein in dorsolateral striatum.

Journal: Toxicology and industrial health 20090201

Title: Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

Journal: PloS one 20090101

Title: 4-Phenyl-1,2,3,6-tetrahydropyridine, an excellent fragment to improve the potency of PARP-1 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20051001

Title: Rat liver microsomal enzyme catalyzed oxidation of 4-phenyl-trans-1-(2-phenylcyclopropyl)-1,2,3,6-tetrahydropyridine.

Journal: Bioorganic & medicinal chemistry 20010701

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