Home Other Building Blocks 104-29-0
104-29-0,MFCD00021990
Catalog No.:AA007I2V

104-29-0 | Chlorphenesin

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25g
98%(GC)
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$24.00   $17.00
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100g
98%
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$35.00   $25.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA007I2V
Chemical Name:
Chlorphenesin
CAS Number:
104-29-0
Molecular Formula:
C9H11ClO3
Molecular Weight:
202.6348
MDL Number:
MFCD00021990
SMILES:
OCC(COc1ccc(cc1)Cl)O
NSC Number:
6401
Properties
Computed Properties
 
Complexity:
135  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
XLogP3:
1.2  

Downstream Synthesis Route

[1]Patent:CH247177,1945,

[1]Synthesis,1989,p.64-65

[2]Synlett,2007,p.619-622

[3]JournaloftheChemicalSociety,1954,p.3669,3672

[4]Tetrahedron,1992,vol.48,p.2373-2384

[5]AgriculturalandBiologicalChemistry,1989,vol.53,p.215-222

[1]JournalofOrganicChemistry,1977,vol.42,p.2260-2264

[1]ChimicaTherapeutica,1969,vol.4,p.200-206

[1]ChimicaTherapeutica,1969,vol.4,p.200-206

Literature

Title: Multicenter study of preservative sensitivity in patients with suspected cosmetic contact dermatitis in Korea.

Journal: The Journal of dermatology 20120801

Title: Relative bioavailability of generic and branded 250-mg and 500-mg oral chlorphenesin carbamate tablets in healthy Korean volunteers: a single-dose, randomized-sequence, open-label, two-period crossover trial.

Journal: Clinical therapeutics 20091101

Title: [Detection of the preservative chlorphenesin in cosmetics by high-performance liquid chromatography].

Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20090101

Title: The synthesis of amphipathic prodrugs of 1,2-diol drugs with saccharide conjugates by high regioselective enzymatic protocol.

Journal: Bioorganic & medicinal chemistry 20070215

Title: Beta-galactosidase catalyzed selective galactosylation of aromatic compounds.

Journal: Biotechnology progress 20060101

Title: Two cases of facial dermatitis due to chlorphenesin in cosmetics.

Journal: Contact dermatitis 20050101

Title: Optimization of chlorphenesin emulgel formulation.

Journal: The AAPS journal 20040901

Title: Medical treatment of the major neuralgias.

Journal: Seminars in neurology 19881201

Title: Effect of a muscle relaxant, chlorphenesin carbamate, on the spinal neurons of rats.

Journal: Japanese journal of pharmacology 19840901

Title: Inhibition of histamine and SRS-A from monkey lung tissue by chlorophenesin.

Journal: Journal of immunology (Baltimore, Md. : 1950) 19710801

Title: H Y Whang, et al. Chlorphenesin: an antigen-associated immunosuppressant. Infect Immun. 1970 Jul;2(1):60-4.

Title: Jingyi Wang, et al. Toxicity of the cosmetic preservatives parabens, phenoxyethanol and chlorphenesin on human meibomian gland epithelial cells. Exp Eye Res. 2020 Jul;196:108057.

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