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104264-80-4
Catalog No.:AA01QAXE

104264-80-4 | 3H-2,7-[3]Octeno-1H-azocino[1′,2′:1,5]pyrrolo[2,3-i]isoquinolin-7(7aH)-ol, 4,4a,9,10,11,12,14a,15-octahydro-5-(9H-pyrido[3,4-b]indol-1-yl)-, hydrochloride (1:1), (2S,4aR,7S,7aR,14aR,15aR)-

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Purity
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Price(USD)
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1mg
99%
1 week  
$447.00   $313.00
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5mg
99%
1 week  
$1,320.00   $924.00
- +
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Technical Information
Catalog Number:
AA01QAXE
Chemical Name:
3H-2,7-[3]Octeno-1H-azocino[1′,2′:1,5]pyrrolo[2,3-i]isoquinolin-7(7aH)-ol, 4,4a,9,10,11,12,14a,15-octahydro-5-(9H-pyrido[3,4-b]indol-1-yl)-, hydrochloride (1:1), (2S,4aR,7S,7aR,14aR,15aR)-
CAS Number:
104264-80-4
Molecular Formula:
C36H45ClN4O
Molecular Weight:
585.2217
SMILES:
O[C@@]12CC/C=C\CCCCN3C[C@]4([C@H]2N2CCCCC=C[C@H]2C4)[C@H](C(=C1)c1nccc2c1[nH]c1c2cccc1)CC3.Cl
Properties

Literature

Title: Hamann M, et al. Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease. J Nat Prod. 2007;70(9):1397-1405.

Title: Kallifatidis G, et al. The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells [published correction appears in Mar Drugs. 2014;12(4):2305-7 Mar Drugs. 2013;11(9):3500-3516. Published 2013 Sep 17.

Title: Winkler JD, et al. Antimalarial activity of a new family of analogues of manzamine A. Org Lett. 2006;8(12):2591-2594.

Title: Palem JR, et al. Manzamine A as a novel inhibitor of herpes simplex virus type-1 replication in cultured corneal cells. Planta Med. 2011;77(1):46-51.

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Tags:104264-80-4 Molecular Formula|104264-80-4 MDL|104264-80-4 SMILES|104264-80-4 3H-2,7-[3]Octeno-1H-azocino[1′,2′:1,5]pyrrolo[2,3-i]isoquinolin-7(7aH)-ol, 4,4a,9,10,11,12,14a,15-octahydro-5-(9H-pyrido[3,4-b]indol-1-yl)-, hydrochloride (1:1), (2S,4aR,7S,7aR,14aR,15aR)-