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105-55-5,MFCD00004925
Catalog No.:AA003DGU

105-55-5 | 1,3-Diethylthiourea

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25g
97%
in stock  
$9.00   $7.00
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500g
95%
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$108.00   $76.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003DGU
Chemical Name:
1,3-Diethylthiourea
CAS Number:
105-55-5
Molecular Formula:
C5H12N2S
Molecular Weight:
132.2272
MDL Number:
MFCD00004925
SMILES:
CCNC(=S)NCC
NSC Number:
3507
Properties
Properties
 
BP:
169.2°C at 760 mmHg  
Form:
Solid  
MP:
75-77°C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
64.8  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
0.6  

Downstream Synthesis Route

[1]Perveen,Shahnaz;AbdulHai,SyedM.;Khan,RashidA.;Khan,KhalidMohammed;Afza,Nighat;Sarfaraz,TahiraB.[SyntheticCommunications,2005,vol.35,#12,p.1663-1674]

[2]Blanco,JoseL.Jimenez;Barria,ClaudioSaitz;Benito,JuanM.;Mellet,CarmenOrtiz;Fuentes,Jose;Santoyo-Gonzales,Francisco;Fernandez,JoseM.Garcia[Synthesis,1999,#11,p.1907-1914]

[3]Ponzio[GazzettaChimicaItaliana,1896,vol.26I,p.326]Anschuetz[JustusLiebigsAnnalenderChemie,1909,vol.371,p.202,225][Chemiker-Zeitung,ChemischeApparatur,1910,vol.34,p.89]

[1]Jangale,AshaD.;Kumavat,PriyankaP.;Wagh,YogeshB.;Tayade,YogeshA.;Mahulikar,PramodP.;Dalal,DipakS.[SyntheticCommunications,2015,vol.45,#2,p.236-244]

[2]Jangale,AshaD.;Kumavat,PriyankaP.;Wagh,YogeshB.;Tayade,YogeshA.;Mahulikar,PramodP.;Dalal,DipakS.[SyntheticCommunications,2015,vol.45,#3,p.376-385]

[3]CurrentPatentAssignee:BRIDGESTONECORPORATION-US2849420,1953,A

[1]Dohertyetal.[JournaloftheAmericanChemicalSociety,1957,vol.79,p.5667,5670]

[1]NestorJr.;Tahilramani;Ho;Goodpasture;Vickery;Ferrandon[JournalofMedicinalChemistry,1992,vol.35,#21,p.3942-3948]

[2]Lacey[JournaloftheChemicalSociety,1954,p.854,859]Finneganetal.[JournalofOrganicChemistry,1953,vol.18,p.779,784]

[3]Percival;Herbst[JournalofOrganicChemistry,1957,vol.22,p.925,931]

[1]Kollenz,Gert;Penn,Gerhard;Ott,Walter;Peters,Karl;Peters,Eva-Maria;etal.[ChemischeBerichte,1984,vol.117,#4,p.1310-1329]

[2]Zingaroetal.[JournalofOrganicChemistry,1953,vol.18,p.292,294]

[3]Indukumari,P.V.;Joshua,C.P.[IndianJournalofChemistry-SectionBOrganicandMedicinalChemistry,1980,vol.19,#8,p.667-671]

[4]CurrentPatentAssignee:PFIZERINC-US2479498,1946,A

Literature

Title: Targeted testing with diethylthiourea often reveals clinically relevant allergic contact dermatitis caused by neoprene rubber.

Journal: Contact dermatitis 20120801

Title: Occupational allergic contact dermatitis caused by diethylthiourea in a neoprene handle of a cleaning trolley.

Journal: Contact dermatitis 20110601

Title: Quantitative assessment of diethylthiourea exposure in two cases of occupational allergic contact dermatitis.

Journal: Contact dermatitis 20110201

Title: Assessment of ion imprinted polymers based on Pd(II) chelate complexes for preconcentration and FAAS determination of palladium.

Journal: Talanta 20101215

Title: Sensitization to thiourea derivatives among Finnish patients with suspected contact dermatitis.

Journal: Contact dermatitis 20100701

Title: Structural and spectroscopic studies of some adducts of silver(I) halides with thiourea and N-ethyl substituted thioureas.

Journal: Dalton transactions (Cambridge, England : 2003) 20100514

Title: Soccer shin guard reactions: allergic and irritant reactions.

Journal: Dermatitis : contact, atopic, occupational, drug 20100101

Title: [Allergic contact dermatitis to diethylthiourea in a neoprene wader].

Journal: Actas dermo-sifiliograficas 20090501

Title: 1 : 1 complexes of silver(I) thiocyanate with (substituted) thiourea ligands.

Journal: Dalton transactions (Cambridge, England : 2003) 20090414

Title: Positive patch-test reactions to mixed dialkyl thioureas: cross-sectional data from the North American Contact Dermatitis Group, 1994 to 2004.

Journal: Dermatitis : contact, atopic, occupational, drug 20080101

Title: Allergic contact dermatitis as a result of diethylthiourea.

Journal: Contact dermatitis 20070901

Title: DNA fragmentation and DNA repair synthesis induced in rat and human thyroid cells by chemicals carcinogenic to the rat thyroid.

Journal: Mutation research 20061030

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: HPLC analysis of alkyl thioureas in an orthopaedic brace and patch testing with pure ethylbutylthiourea.

Journal: Contact dermatitis 20040101

Title: Carcinogenic effect of combined administration of 2,4-diaminoanisole sulfate, 4,4'-thiodianiline and N,N'-diethylthiourea in male Wistar rats.

Journal: Neoplasma 20020101

Title: Some thyrotropic agents.

Journal: IARC monographs on the evaluation of carcinogenic risks to humans 20010101

Title: Synergistic enhancement of thyroid tumor induction by 2,4-diaminoanisole sulfate, N,N'-diethylthiourea and 4,4'-thiodianiline in male F344 rats.

Journal: Carcinogenesis 19910801

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