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1051387-90-6,MFCD31620831
Catalog No.:AA01DU77

1051387-90-6 | Spi112

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25mg
≥98%
in stock  
$186.00   $130.00
- +
50mg
≥98%
in stock  
$348.00   $243.00
- +
100mg
≥98%
in stock  
$620.00   $434.00
- +
250mg
≥98%
in stock  
$1,093.00   $765.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01DU77
Chemical Name:
Spi112
CAS Number:
1051387-90-6
Molecular Formula:
C22H17FN4O5S
Molecular Weight:
468.4576
MDL Number:
MFCD31620831
SMILES:
Fc1ccc(cc1)CNS(=O)(=O)c1ccc2c(c1)/C(=N/Nc1cccc(c1)C(=O)O)/C(=O)N2
Properties

Downstream Synthesis Route
C15H11FN2O4S 
  38235-71-1    1051387-90-6 

[1]Locationinpatent:experimentalpartLawrence,HarshaniR.;Pireddu,Roberta;Chen,Liwei;Luo,Yunting;Sung,Shen-Shu;Szymanski,AnnMarie;Yip,M.L.Richard;Guida,WayneC.;Sebti,SaïdM.;Wu,Jie;Lawrence,NicholasJ.[JournalofMedicinalChemistry,2008,vol.51,#16,p.4948-4956]

Literature

Title: Chen L, et al. Inhibition of cellular Shp2 activity by a methyl ester analog of SPI-112. Biochem Pharmacol. 2010 Sep 15;80(6):801-10.

Title: Lawrence HR, et al. Inhibitors of Src homology-2 domain containing protein tyrosine phosphatase-2 (Shp2) based on oxindole scaffolds. J Med Chem. 2008 Aug 28;51(16):4948-56.

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SDS
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Tags:1051387-90-6 Molecular Formula|1051387-90-6 MDL|1051387-90-6 SMILES|1051387-90-6 Spi112
Catalog No.: AA01DU77
1051387-90-6,MFCD31620831
1051387-90-6 | Spi112
Pack Size： 25mg
Purity： ≥98%
in stock
$186.00 $130.00
Pack Size： 50mg
Purity： ≥98%
in stock
$348.00 $243.00
Pack Size： 100mg
Purity： ≥98%
in stock
$620.00 $434.00
Pack Size： 250mg
Purity： ≥98%
in stock
$1,093.00 $765.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA01DU77
Chemical Name: Spi112
CAS Number: 1051387-90-6
Molecular Formula: C22H17FN4O5S
Molecular Weight: 468.4576
MDL Number: MFCD31620831
SMILES: Fc1ccc(cc1)CNS(=O)(=O)c1ccc2c(c1)/C(=N/Nc1cccc(c1)C(=O)O)/C(=O)N2
Properties
Downstream Synthesis Route
C15H11FN2O4S 
  38235-71-1    1051387-90-6 

[1]Locationinpatent:experimentalpartLawrence,HarshaniR.;Pireddu,Roberta;Chen,Liwei;Luo,Yunting;Sung,Shen-Shu;Szymanski,AnnMarie;Yip,M.L.Richard;Guida,WayneC.;Sebti,SaïdM.;Wu,Jie;Lawrence,NicholasJ.[JournalofMedicinalChemistry,2008,vol.51,#16,p.4948-4956]

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536714-22-4
955695-94-0
955695-94-0
1225548-28-6
1225548-28-6
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