Home Fluorides 105565-55-7
105565-55-7,MFCD04039786
Catalog No.:AA008Y1E

105565-55-7 | ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE

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5mg
≥98%(HPLC)
in stock  
$213.00   $149.00
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10mg
≥98%(HPLC)
in stock  
$304.00   $213.00
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25mg
≥98%(HPLC)
in stock  
$579.00   $405.00
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50mg
≥98%(HPLC)
in stock  
$941.00   $659.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008Y1E
Chemical Name:
ALPHA-(4-FLUOROPHENYL)-4-(5-FLUORO-2-PYRIMIDINYL)-1-PIPERAZINEBUTANOL HYDROCHLORIDE
CAS Number:
105565-55-7
Molecular Formula:
C18H23ClF2N4O
Molecular Weight:
384.8512
MDL Number:
MFCD04039786
SMILES:
Fc1ccc(cc1)C(CCCN1CCN(CC1)c1ncc(cn1)F)O.Cl
Properties
Computed Properties
 
Complexity:
379  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Straub tail reaction in mice treated with σ(1) receptor antagonist in combination with methamphetamine.

Journal: Brain research 20121030

Title: The sigma-1 antagonist BMY-14802 inhibits L-DOPA-induced abnormal involuntary movements by a WAY-100635-sensitive mechanism.

Journal: Psychopharmacology 20090701

Title: Sigma1 receptor antagonists determine the behavioral pattern of the methamphetamine-induced stereotypy in mice.

Journal: Psychopharmacology 20090501

Title: Sigma ligands, but not N-methyl-D-aspartate antagonists, reduce levodopa-induced dyskinesias.

Journal: Neuroreport 20080108

Title: Neurosteroid dehydroepiandrosterone sulfate enhances spontaneous glutamate release in rat prelimbic cortex through activation of dopamine D1 and sigma-1 receptor.

Journal: Neuropharmacology 20070301

Title: Intrathecal treatment with sigma1 receptor antagonists reduces formalin-induced phosphorylation of NMDA receptor subunit 1 and the second phase of formalin test in mice.

Journal: British journal of pharmacology 20060601

Title: Antidiarrhoeal properties of a novel sigma ligand (JO 2871) on toxigenic diarrhoea in mice: mechanisms of action.

Journal: Gut 20021001

Title: BMY-14802 reversed the sigma receptor agonist-induced neck dystonia in rats.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 19960101

Title: The sigma receptor ligand (+/-)-BMY 14802 prevents methamphetamine-induced dopaminergic neurotoxicity via interactions at dopamine receptors.

Journal: The Journal of pharmacology and experimental therapeutics 19940401

Title: The involvement of sigma and phencyclidine receptors in the action of antipsychotic drugs.

Journal: Pharmacology & toxicology 19920801

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