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10574-69-3,MFCD00086924
Catalog No.:AA003IW8

10574-69-3 | 3-Benzylrhodanine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$19.00   $14.00
- +
5g
95%
in stock  
$54.00   $38.00
- +
25g
>98.0%(GC)
in stock  
$109.00   $76.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003IW8
Chemical Name:
3-Benzylrhodanine
CAS Number:
10574-69-3
Molecular Formula:
C10H9NOS2
Molecular Weight:
223.3146
MDL Number:
MFCD00086924
SMILES:
O=C1CSC(=S)N1Cc1ccccc1
NSC Number:
142477
Properties
Properties
 
BP:
353°C at 760 mmHg  
Form:
Solid  
MP:
89°C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
249  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
2  
XLogP3:
2.3  

Downstream Synthesis Route

[1]CurrentPatentAssignee:CTIBIOPHARMACORP.-US2004/2526,2004,A1

[2]Holmberg[JournalfurpraktischeChemie(Leipzig1954),1910,vol.<2>81,p.456]

[3]Locationinpatent:experimentalpartRadi,Marco;Botta,Lorenzo;Casaluce,Gianni;Bernardini,Martina;Botta,Maurizio[JournalofCombinatorialChemistry,2010,vol.12,#1,p.200-205]

[4]Locationinpatent:experimentalpartRinaldi,Marta;Tintori,Cristina;Franchi,Luigi;Vignaroli,Giulia;Innitzer,Anna;Massa,Silvio;Este,JoseA.;Gonzalo,Encarna;Christ,Frauke;Debyser,Zeger;Botta,Maurizio[ChemMedChem,2011,vol.6,#2,p.343-352]

[1]CurrentPatentAssignee:GOSSAMERBIOINC-WO2018/126072,2018,A1Locationinpatent:Paragraph0285;0286

[2]Sing,WanTheng;Lee,ChengLeng;Yeo,SuLing;Lim,SiewPheng;Sim,MuiMui[BioorganicandMedicinalChemistryLetters,2001,vol.11,#2,p.91-94]

10574-69-3    55514-14-2   
5-(3-methyl-2(3H)-benzothiazolylidene)-2-thioxo-3-benzyl-4-thiazolidinone 

[1]CurrentPatentAssignee:JAPANSCIENCEANDTECHNOLOGYAGENCY-EP1623981,2006,A1Locationinpatent:Page/Pagecolumn10

[2]Takasu,Kiyosei;Inoue,Hiroshi;Kim,Hye-Sook;Suzuki,Makoto;Shishido,Tadao;Wataya,Yusuke;Ihara,Masataka[JournalofMedicinalChemistry,2002,vol.45,#5,p.995-998]

[3]Li,Xiaokai;Srinivasan,SharanR.;Connarn,Jamie;Ahmad,Atta;Young,ZapporahT.;Kabza,AdamM.;Zuiderweg,Erik.R.P.;Sun,Duxin;Gestwicki,JasonE.[ACSMedicinalChemistryLetters,2013,vol.4,#11,p.1042-1047]

10574-69-3    104-88-1   
(Z)-3-benzyl-5-(4-chlorobenzylidene)-2-thioxothiazolidin-4-one 

[1]Powers,JayP.;Piper,DerekE.;Li,Yang;Mayorga,Veronica;Anzola,John;Chen,JamesM.;Jaen,JuanC.;Lee,Gary;Liu,Jinqian;Peterson,M.Greg;Tonn,GeorgeR.;Ye,Qiuping;Walker,NigelP.C.;Wang,Zhulun[JournalofMedicinalChemistry,2006,vol.49,#3,p.1034-1046]

[2]Mandal,SubhankarP.;Mithuna;Garg,Aakriti;Sahetya,SanjanaS.;Nagendra;Sripad;Manjunath,MendonManisha;Sitaram;Soni,Mukesh;Baig,R.Nasir;Kumar,S.Vasanth;Kumar,B.R.Prashantha[RSCAdvances,2016,vol.6,#63,p.58641-58653]

[1]CurrentPatentAssignee:RIGELPHARMACEUTICALSINC-WO2004/43955,2004,A1Locationinpatent:Page47

Literature

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors.

Journal: Journal of medicinal chemistry 20051117

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