Title: An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20170401
Title: Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders.
Journal: Toxicology and applied pharmacology 20160401
Title: Integrated preclinical and clinical development of S-trans, trans-Farnesylthiosalicylic Acid (FTS, Salirasib) in pancreatic cancer.
Journal: Investigational new drugs 20121201
Title: Farnesol inhibits in vitro growth of the Cryptococcus neoformans species complex with no significant changes in virulence-related exoenzymes.
Journal: Veterinary microbiology 20121012
Title: Celecoxib enhances the anti-inflammatory effects of farnesylthiosalicylic acid on T cells independent of prostaglandin E(2) production.
Journal: Inflammation 20121001
Title: Farnesol and cyclic AMP signaling effects on the hypha-to-yeast transition in Candida albicans.
Journal: Eukaryotic cell 20121001
Title: A convergent stereocontrolled total synthesis of (-)-terpestacin.
Journal: Organic & biomolecular chemistry 20120728
Title: HIV-1 infection of human macrophages directly induces viperin which inhibits viral production.
Journal: Blood 20120726
Title: Proteome analysis of the farnesol-induced stress response in Aspergillus nidulans--The role of a putative dehydrin.
Journal: Journal of proteomics 20120716
Title: Quorum sensing activity in Ophiostoma ulmi: effects of fusel oils and branched chain amino acids on yeast-mycelial dimorphism.
Journal: Journal of applied microbiology 20120701
Title: Atorvastatin attenuates TNF-α-induced increase of glucose oxidation through PGC-1α upregulation in cardiomyocytes.
Journal: Journal of cardiovascular pharmacology 20120601
Title: Miconazole, a pharmacological barrier to skin fungal infections.
Journal: Expert opinion on pharmacotherapy 20120601
Title: Computer-based identification of a novel LIMK1/2 inhibitor that synergizes with salirasib to destabilize the actin cytoskeleton.
Journal: Oncotarget 20120601
Title: Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells.
Journal: Biochemical and biophysical research communications 20120504
Title: Pravastatin inhibits farnesol production in Candida albicans and improves survival in a mouse model of systemic candidiasis.
Journal: Medical mycology 20120501
Title: Analgesic potential of intrathecal farnesyl thiosalicylic acid and GW 5074 in vincristine-induced neuropathic pain in rats.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120501
Title: Waikialoid A suppresses hyphal morphogenesis and inhibits biofilm development in pathogenic Candida albicans.
Journal: Journal of natural products 20120427
Title: Farnesylthiosalicylic acid (salirasib) inhibits Rheb in TSC2-null ELT3 cells: a potential treatment for lymphangioleiomyomatosis.
Journal: International journal of cancer 20120315
Title: Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis).
Journal: Journal of experimental botany 20120301
Title: Terpene alcohols inhibit de novo sphingolipid biosynthesis.
Journal: Planta medica 20120301
Title: Farnesyltransferase inhibitors: molecular evidence of therapeutic efficacy in acute lymphoblastic leukemia through cyclin D1 inhibition.
Journal: Anticancer research 20120301
Title: FTS and 2-DG induce pancreatic cancer cell death and tumor shrinkage in mice.
Journal: Cell death & disease 20120301
Title: Prevention of induced colitis in mice by the ras antagonist farnesylthiosalicylic acid.
Journal: Digestive diseases and sciences 20120201
Title: Benzo(a)pyrene-induced pulmonary inflammation, edema, surfactant dysfunction, and injuries in rats: alleviation by farnesol.
Journal: Experimental lung research 20120201
Title: Ras inhibition by FTS attenuates brain tumor growth in mice by direct antitumor activity and enhanced reactivity of cytotoxic lymphocytes.
Journal: Oncotarget 20120201
Title: Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation.
Journal: Neuroscience 20120127
Title: Candida and invasive candidiasis: back to basics.
Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20120101
Title: Confocal laser scanning microscopy analysis of S. epidermidis biofilms exposed to farnesol, vancomycin and rifampicin.
Journal: BMC research notes 20120101
Title: Retigeric acid B attenuates the virulence of Candida albicans via inhibiting adenylyl cyclase activity targeted by enhanced farnesol production.
Journal: PloS one 20120101
Title: Functional characterization of the small heat shock protein Hsp12p from Candida albicans.
Journal: PloS one 20120101
Title: Farnesol decreases biofilms of Staphylococcus epidermidis and exhibits synergy with nafcillin and vancomycin.
Journal: Pediatric research 20111201
Title: Candida albicans developmental regulation: adenylyl cyclase as a coincidence detector of parallel signals.
Journal: Current opinion in microbiology 20111201
Title: Alcohol-based quorum sensing plays a role in adhesion and sliding motility of the yeast Debaryomyces hansenii.
Journal: FEMS yeast research 20111201
Title: [Analysis on the compositions of volatile oil of Alpinia henryi with GC-MS method].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20111201
Title: Hepatic FXR: key regulator of whole-body energy metabolism.
Journal: Trends in endocrinology and metabolism: TEM 20111101
Title: Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways.
Journal: American journal of physiology. Endocrinology and metabolism 20111101
Title: Zap1 control of cell-cell signaling in Candida albicans biofilms.
Journal: Eukaryotic cell 20111101
Title: Roles of Ras1 membrane localization during Candida albicans hyphal growth and farnesol response.
Journal: Eukaryotic cell 20111101
Title: Characterization of a hyperactive Cyr1 mutant reveals new regulatory mechanisms for cellular cAMP levels in Candida albicans.
Journal: Molecular microbiology 20111101
Title: Inhibitory effect of farnesylthiosalicylic acid on mediators release by mast cells: preferential inhibition of prostaglandin D(2) and tumor necrosis factor-α release.
Journal: Inflammation 20111001
Title: Inhibition of contact sensitivity by farnesylthiosalicylic acid-amide, a potential Rap1 inhibitor.
Journal: The Journal of investigative dermatology 20111001
Title: Effect of farnesol on structure and composition of Staphylococcus epidermidis biofilm matrix.
Journal: Current microbiology 20111001
Title: Farnesol-induced cell death in the filamentous fungus Aspergillus nidulans.
Journal: Biochemical Society transactions 20111001
Title: Quorum sensing in fungi: Q&A.
Journal: PLoS pathogens 20111001
Title: Biosynthesis of unnatural bacteriochlorophyll c derivatives esterified with α,ω-diols in the green sulfur photosynthetic bacterium Chlorobaculum tepidum.
Journal: Biochemistry 20110913
Title: Antimicrobial traits of tea- and cranberry-derived polyphenols against Streptococcus mutans.
Journal: Caries research 20110901
Title: Enzymatic synthesis of farnesyl laurate in organic solvent: initial water activity, kinetics mechanism, optimization of continuous operation using packed bed reactor and mass transfer studies.
Journal: Bioprocess and biosystems engineering 20110801
Title: Phenotypic reversion of invasive neurofibromin-deficient schwannoma by FTS: Ras inhibition reduces BMP4/Erk/Smad signaling.
Journal: Molecular cancer therapeutics 20110801
Title: Modulation of morphogenesis in Candida albicans by various small molecules.
Journal: Eukaryotic cell 20110801
Title: The quorum-sensing molecules farnesol/homoserine lactone and dodecanol operate via distinct modes of action in Candida albicans.
Journal: Eukaryotic cell 20110801
Title: Roles for farnesol and ABA in Arabidopsis flower development.
Journal: Plant signaling & behavior 20110801
Title: Effect of farnesol on mevalonate pathway of Staphylococcus aureus.
Journal: The Journal of antibiotics 20110801
Title: A phase II trial of Salirasib in patients with lung adenocarcinomas with KRAS mutations.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110801
Title: Farnesol attenuates 1,2-dimethylhydrazine induced oxidative stress, inflammation and apoptotic responses in the colon of Wistar rats.
Journal: Chemico-biological interactions 20110715
Title: Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains.
Journal: Mutation research 20110714
Title: The geranyl-modified tryptophan residue is crucial for ComXRO-E-2 pheromone biological activity.
Journal: Bioorganic & medicinal chemistry letters 20110701
Title: ZL11n is a novel nitric oxide-releasing derivative of farnesylthiosalicylic acid that induces apoptosis in human hepatoma HepG2 cells via MAPK/mitochondrial pathways.
Journal: Biochemical and biophysical research communications 20110617
Title: Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis.
Journal: The Plant journal : for cell and molecular biology 20110601
Title: Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol.
Journal: Chemico-biological interactions 20110530
Title: Evidence for differential biosynthesis of juvenile hormone (and related) sesquiterpenoids in Drosophila melanogaster.
Journal: General and comparative endocrinology 20110515
Title: Novel nitric oxide-releasing derivatives of farnesylthiosalicylic acid: synthesis and evaluation of antihepatocellular carcinoma activity.
Journal: Journal of medicinal chemistry 20110512
Title: Influences of trans-trans farnesol, a membrane-targeting sesquiterpenoid, on Streptococcus mutans physiology and survival within mixed-species oral biofilms.
Journal: International journal of oral science 20110401
Title: Drimenol: A versatile synthon for compounds with trans-drimane skeleton.
Journal: Natural product communications 20110401
Title: Farnesol as antibiotics adjuvant in Staphylococcus epidermidis control in vitro.
Journal: The American journal of the medical sciences 20110301
Title: Electrohydrodynamic deposition of nanotitanium doped hydroxyapatite coating for medical and dental applications.
Journal: Journal of materials science. Materials in medicine 20110301
Title: Chemoprevention of hepatocellular carcinoma. Proof of concept in animal models.
Journal: Acta gastro-enterologica Belgica 20110301
Title: Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis.
Journal: FEBS letters 20110204
Title: Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: a new drug combination for cancer therapy.
Journal: International journal of cancer 20110201
Title: In vitro and in vivo activity of three sesquiterpenes against L(3) larvae of Anisakis type I.
Journal: Experimental parasitology 20110201
Title: Correlation between bilirubin glucuronidation and estradiol-3-gluronidation in the presence of model UDP-glucuronosyltransferase 1A1 substrates/inhibitors.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110201
Title: The Aspergillus nidulans nucA(EndoG) homologue is not involved in cell death.
Journal: Eukaryotic cell 20110201
Title: Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines.
Journal: Acta oncologica (Stockholm, Sweden) 20110101
Title: Composite fiber structures with antiproliferative agents exhibit advantageous drug delivery and cell growth inhibition in vitro.
Journal: Journal of pharmaceutical sciences 20110101
Title: Linking quorum sensing regulation and biofilm formation by Candida albicans.
Journal: Methods in molecular biology (Clifton, N.J.) 20110101
Title: The influence of additives on the nanoscopic dynamics of the phospholipid dimyristoylphosphatidylcholine.
Journal: Biochimica et biophysica acta 20110101
Title: Alkynyl-farnesol reporters for detection of protein S-prenylation in cells.
Journal: Molecular bioSystems 20110101
Title: The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species.
Journal: BMC biochemistry 20110101
Title: Development of a novel PPARγ ligand screening system using pinpoint fluorescence-probed protein.
Journal: Bioscience, biotechnology, and biochemistry 20110101
Title: The Ras antagonist, farnesylthiosalicylic acid (FTS), decreases fibrosis and improves muscle strength in dy/dy mouse model of muscular dystrophy.
Journal: PloS one 20110101
Title: Ras inhibition induces insulin sensitivity and glucose uptake.
Journal: PloS one 20110101
Title: Bisbibenzyls, a new type of antifungal agent, inhibit morphogenesis switch and biofilm formation through upregulation of DPP3 in Candida albicans.
Journal: PloS one 20110101
Title: Farnesol-induced apoptosis in Candida albicans is mediated by Cdr1-p extrusion and depletion of intracellular glutathione.
Journal: PloS one 20110101
Title: The combined treatment of Copaxone and Salirasib attenuates experimental autoimmune encephalomyelitis (EAE) in mice.
Journal: Journal of neuroimmunology 20101215
Title: Immunotoxicity activity of the major essential oil of Filipendula glaberrima against Aedes aegypti L.
Journal: Immunopharmacology and immunotoxicology 20101201
Title: The roles played by Aspergillus nidulans apoptosis-inducing factor (AIF)-like mitochondrial oxidoreductase (AifA) and NADH-ubiquinone oxidoreductases (NdeA-B and NdiA) in farnesol resistance.
Journal: Fungal genetics and biology : FG & B 20101201
Title: Allergic contact dermatitis caused by farnesol: clinical relevance.
Journal: Cutaneous and ocular toxicology 20101201
Title: Involvement of the Aspergillus nidulans protein kinase C with farnesol tolerance is related to the unfolded protein response.
Journal: Molecular microbiology 20101201
Title: Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane.
Journal: Biophysical journal 20101117
Title: Separation of attogram terpenes by the capillary zone electrophoresis with fluorometric detection.
Journal: Journal of chromatography. A 20101112
Title: Lipidation by the host prenyltransferase machinery facilitates membrane localization of Legionella pneumophila effector proteins.
Journal: The Journal of biological chemistry 20101105
Title: Ultra high performance liquid chromatography tandem mass spectrometry analysis of quorum-sensing molecules of Candida albicans.
Journal: Journal of pharmaceutical and biomedical analysis 20101102
Title: In vitro pro- and anti-inflammatory responses to viable Candida albicans yeasts by a murine macrophage cell line.
Journal: Medical mycology 20101101
Title: Identification of a novel abscisic acid-regulated farnesol dehydrogenase from Arabidopsis.
Journal: Plant physiology 20101101
Title: Farnesol, a potential efflux pump inhibitor in Mycobacterium smegmatis.
Journal: Molecules (Basel, Switzerland) 20101029
Title: Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway.
Journal: Biotechnology and bioengineering 20101015
Title: Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line.
Journal: FEMS immunology and medical microbiology 20101001
Title: Candida albicans-produced farnesol stimulates Pseudomonas quinolone signal production in LasR-defective Pseudomonas aeruginosa strains.
Journal: Microbiology (Reading, England) 20101001
Title: The quorum-sensing molecule E,E-farnesol--its variable secretion and its impact on the growth and metabolism of Candida species.
Journal: Yeast (Chichester, England) 20100901
Title: Proto-oncogenic H-Ras, K-Ras, and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase.
Journal: Cell research 20100801
Title: 2,3-Dihydrohomofarnesal: female sex attractant pheromone component of Callosobruchus rhodesianus (Pic).
Journal: Journal of chemical ecology 20100801
Title: Galectin-3 promotes chronic activation of K-Ras and differentiation block in malignant thyroid carcinomas.
Journal: Molecular cancer therapeutics 20100801
Title: Farnesol misplaces tip-localized Rho proteins and inhibits cell wall integrity signalling in Aspergillus fumigatus.
Journal: Molecular microbiology 20100601
Title: Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation.
Journal: American journal of physiology. Cell physiology 20100601
Title: Salirasib in the treatment of pancreatic cancer.
Journal: Future oncology (London, England) 20100601
Title: Ras inhibits endoplasmic reticulum stress in human cancer cells with amplified Myc.
Journal: International journal of cancer 20100515
Title: Synthesis and evaluation of nitric oxide-releasing derivatives of farnesylthiosalicylic acid as anti-tumor agents.
Journal: Bioorganic & medicinal chemistry 20100515
Title: Farnesol induces hydrogen peroxide resistance in Candida albicans yeast by inhibiting the Ras-cyclic AMP signaling pathway.
Journal: Eukaryotic cell 20100401
Title: Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10.
Journal: Bioorganic & medicinal chemistry 20100401
Title: Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile.
Journal: Chemico-biological interactions 20100330
Title: Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells.
Journal: Biochemical pharmacology 20100301
Title: Scanning chimeragenesis: the approach used to change the substrate selectivity of fatty acid monooxygenase CYP102A1 to that of terpene omega-hydroxylase CYP4C7.
Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100201
Title: Molecular mechanisms involved in farnesol-induced apoptosis.
Journal: Cancer letters 20100128
Title: Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signaling.
Journal: Oncogene 20100121
Title: The Ras antagonist farnesylthiosalicylic acid ameliorates experimental myocarditis in the rat.
Journal: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20100101
Title: Farnesol-modified biodegradable polyurethanes for cartilage tissue engineering.
Journal: Journal of biomedical materials research. Part A 20100101
Title: Phase 1 first-in-human clinical study of S-trans,trans-farnesylthiosalicylic acid (salirasib) in patients with solid tumors.
Journal: Cancer chemotherapy and pharmacology 20100101
Title: In vivo and in vitro skin absorption of lipophilic compounds, dibutyl phthalate, farnesol and geraniol in the hairless guinea pig.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
Title: Farnesol induces apoptosis and oxidative stress in the fungal pathogen Penicillium expansum.
Journal: Mycologia 20100101
Title: Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition.
Journal: Molecular cancer 20100101
Title: Cellular interactions of farnesol, a quorum-sensing molecule produced by Candida albicans.
Journal: Future microbiology 20091201
Title: Acid-catalyzed cyclization of terpenes under homogeneous and heterogeneous conditions as probed through stereoisotopic studies: a concerted process with competing preorganized chair and boat transition states.
Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20091109
Title: The effects of farnesol on Staphylococcus aureus biofilms and osteoblasts. An in vitro study.
Journal: The Journal of bone and joint surgery. American volume 20091101
Title: Effects of cholesterol and nuclear hormone receptor agonists on the production of transforming growth factor-beta in macrophages.
Journal: Bulletin of experimental biology and medicine 20090901
Title: Ras inhibition increases the frequency and function of regulatory T cells and attenuates type-1 diabetes in non-obese diabetic mice.
Journal: European journal of pharmacology 20090815
Title: Effect of farnesol on planktonic and biofilm cells of Staphylococcus epidermidis.
Journal: Current microbiology 20090801
Title: Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors.
Journal: Cardiovascular research 20090801
Title: Chemopreventive effect of farnesol on DMBA/TPA-induced skin tumorigenesis: involvement of inflammation, Ras-ERK pathway and apoptosis.
Journal: Life sciences 20090731
Title: The Ras inhibitor farnesylthiosalicyclic acid (FTS) prevents nodule formation and development of preneoplastic foci of altered hepatocytes in rats.
Journal: European journal of cancer (Oxford, England : 1990) 20090701
Title: Alkaline pH enhances farnesol production by Saccharomyces cerevisiae.
Journal: Journal of bioscience and bioengineering 20090701
Title: A two-component female-produced pheromone of the spider Pholcus beijingensis.
Journal: Journal of chemical ecology 20090701
Title: Novel farnesylthiosalicylate (FTS)-eluting composite structures.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628
Title: Farnesol-induced apoptosis in Candida albicans.
Journal: Antimicrobial agents and chemotherapy 20090601
Title: Suppression of anti-Candida activity of macrophages by a quorum-sensing molecule, farnesol, through induction of oxidative stress.
Journal: Microbiology and immunology 20090601
Title: Ras inhibition attenuates myocardial ischemia-reperfusion injury.
Journal: Biochemical pharmacology 20090515
Title: Proteomic analysis of human low-density lipoprotein reveals the presence of prenylcysteine lyase, a hydrogen peroxide-generating enzyme.
Journal: Proteomics 20090301
Title: Biofilm formation by Pneumocystis spp.
Journal: Eukaryotic cell 20090201
Title: Farnesol promotes epithelial cell defense against Candida albicans through Toll-like receptor 2 expression, interleukin-6 and human beta-defensin 2 production.
Journal: Cytokine 20090201
Title: New derivatives of farnesylthiosalicylic acid (salirasib) for cancer treatment: farnesylthiosalicylamide inhibits tumor growth in nude mice models.
Journal: Journal of medicinal chemistry 20090108
Title: Prenyl alcohol production by expression of exogenous isopentenyl diphosphate isomerase and farnesyl diphosphate synthase genes in Escherichia coli.
Journal: Bioscience, biotechnology, and biochemistry 20090101
Title: Antimicrobial effect of farnesol, a Candida albicans quorum sensing molecule, on Paracoccidioides brasiliensis growth and morphogenesis.
Journal: Annals of clinical microbiology and antimicrobials 20090101
Title: Lipid signaling in pathogenic fungi.
Journal: Annual review of microbiology 20090101
Title: Recovery of E,E-farnesol from cultures of yeast erg9 mutants: extraction with polymeric beads and purification by normal-phase chromatography.
Journal: Biotechnology progress 20090101
Title: [Biofilm caused by fungi--structure, quorum sensing, morphogenetic changes, resistance to drugs].
Journal: Wiadomosci parazytologiczne 20090101
Title: Naturally occurring molecules as alternative therapeutic agents against cariogenic biofilms.
Journal: Advances in dental research 20090101
Title: Farnesol inhibits cell proliferation and induces apoptosis after partial hepatectomy in rats.
Journal: Acta cirurgica brasileira 20090101
Title: Influences of naturally occurring agents in combination with fluoride on gene expression and structural organization of Streptococcus mutans in biofilms.
Journal: BMC microbiology 20090101
Title: Effects of two terpene alcohols on the antibacterial activity and the mode of action of farnesol against Staphylococcus aureus.
Journal: Molecules (Basel, Switzerland) 20081209
Title: Benzo(a)pyrene-induced genotoxicity: attenuation by farnesol in a mouse model.
Journal: Journal of enzyme inhibition and medicinal chemistry 20081201
Title: [Quorum sensing in fungal pathogenesis].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20081201
Title: Farnesol ameliorates massive inflammation, oxidative stress and lung injury induced by intratracheal instillation of cigarette smoke extract in rats: an initial step in lung chemoprevention.
Journal: Chemico-biological interactions 20081125
Title: Fragrance material review on farnesol.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081101
Title: Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats.
Journal: Molecular cancer therapeutics 20081101
Title: Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase.
Journal: Molecular microbiology 20081001
Title: Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms.
Journal: Applied microbiology and biotechnology 20080901
Title: Farnesol, a fungal quorum-sensing molecule triggers apoptosis in human oral squamous carcinoma cells.
Journal: Neoplasia (New York, N.Y.) 20080901
Title: Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols.
Journal: Journal of bioscience and bioengineering 20080901
Title: Natural isoprenoids are able to reduce inflammation in a mouse model of mevalonate kinase deficiency.
Journal: Pediatric research 20080801
Title: Herbal isoprenols induce apoptosis in human colon cancer cells through transcriptional activation of PPARgamma.
Journal: Cancer investigation 20080801
Title: Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents.
Journal: Infection control and hospital epidemiology 20080801
Title: Analytical method for determination of allylic isoprenols in rat tissues by liquid chromatography/tandem mass spectrometry following chemical derivatization with 3-nitrophtalic anhydride.
Journal: Journal of pharmaceutical and biomedical analysis 20080715
Title: Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes.
Journal: Lipids 20080701
Title: C-geranylated chalcones from the stems of Angelica keiskei with superoxide-scavenging activity.
Journal: Journal of natural products 20080701
Title: Protective effects of farnesol against oral candidiasis in mice.
Journal: Microbiology and immunology 20080701
Title: Strategies to enhance the biological effects of fluoride on dental biofilms.
Journal: Advances in dental research 20080701
Title: [Chemical constituents from the seed of Chimonanthus praecox extracted by supercritical carbon dioxide].
Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080701
Title: Determination of salirasib (S-trans,trans-farnesylthiosalicylic acid) in human plasma using liquid chromatography-tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080615
Title: NF-kappaB-dependent transcriptional activation in lung carcinoma cells by farnesol involves p65/RelA(Ser276) phosphorylation via the MEK-MSK1 signaling pathway.
Journal: The Journal of biological chemistry 20080613
Title: The effect of mutation of F87 on the properties of CYP102A1-CYP4C7 chimeras: altered regiospecificity and substrate selectivity.
Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080601
Title: Candida albicans Tup1 is involved in farnesol-mediated inhibition of filamentous-growth induction.
Journal: Eukaryotic cell 20080601
Title: N-Ras or K-Ras inhibition increases the number and enhances the function of Foxp3 regulatory T cells.
Journal: European journal of immunology 20080601
Title: Signal-mediated interactions between Pseudomonas aeruginosa and Candida albicans.
Journal: Journal of medical microbiology 20080501
Title: Competition between native liver and graft in auxiliary liver transplantation in a rat model.
Journal: Transplantation proceedings 20080501
Title: Metabolic basis of visual cycle inhibition by retinoid and nonretinoid compounds in the vertebrate retina.
Journal: The Journal of biological chemistry 20080411
Title: Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal.
Journal: The Journal of organic chemistry 20080404
Title: The effect of Ras inhibition on the proliferation, apoptosis and matrix metalloproteases activity in rat hepatic stellate cells.
Journal: Digestive diseases and sciences 20080401
Title: Activation of TRPA1 by farnesyl thiosalicylic acid.
Journal: Molecular pharmacology 20080401
Title: Homofarnesals: female sex attractant pheromone components of the southern cowpea weevil, Callosobruchus chinensis.
Journal: Journal of chemical ecology 20080401
Title: Influence of farnesol on the morphogenesis of Aspergillus niger.
Journal: Journal of basic microbiology 20080401
Title: Two different mechanisms for adhesion of Gram-negative bacterium, Pseudomonas fluorescens LP6a, to an oil-water interface.
Journal: Colloids and surfaces. B, Biointerfaces 20080315
Title: Influence of heterocyclic and oxime-containing farnesol analogs on quorum sensing and pathogenicity in Candida albicans.
Journal: Bioorganic & medicinal chemistry 20080215
Title: Inhibition of Fusarium graminearum growth and development by farnesol.
Journal: FEMS microbiology letters 20080201
Title: Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activation.
Journal: Breast cancer research and treatment 20080101
Title: Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats.
Journal: Clinical science (London, England : 1979) 20080101
Title: Orally administered FTS (salirasib) inhibits human pancreatic tumor growth in nude mice.
Journal: Cancer chemotherapy and pharmacology 20080101
Title: Farnesol and dodecanol effects on the Candida albicans Ras1-cAMP signalling pathway and the regulation of morphogenesis.
Journal: Molecular microbiology 20080101
Title: Inhibitors of chronically active ras: potential for treatment of human malignancies.
Journal: Recent patents on anti-cancer drug discovery 20080101
Title: The Ras inhibitor farnesylthiosalicylic acid (Salirasib) disrupts the spatiotemporal localization of active Ras: a potential treatment for cancer.
Journal: Methods in enzymology 20080101
Title: [Farnesol as a quorum-sensing molecule in Candida albicans].
Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20080101
Title: Screening of terpenes and derivatives for antimycobacterial activity; identification of geranylgeraniol and geranylgeranyl acetate as potent inhibitors of Mycobacterium tuberculosis in vitro.
Journal: Planta medica 20071001
Title: Characterization of (E,E)-farnesol and its fatty acid esters from anal scent glands of nutria (Myocastor coypus) by gas chromatography-mass spectrometry and gas chromatography-infrared spectrometry.
Journal: Journal of chromatography. A 20070921
Title: Hypoxia enhances metastatic efficiency in HT1080 fibrosarcoma cells by increasing cell survival in lungs, not cell adhesion and invasion.
Journal: Cancer research 20070815
Title: Farnesol-induced apoptosis in human lung carcinoma cells is coupled to the endoplasmic reticulum stress response.
Journal: Cancer research 20070815
Title: Sesquiterpene farnesol as a competitive inhibitor of lipase activity of Staphylococcus aureus.
Journal: FEMS microbiology letters 20070801
Title: Farnesol-mediated inhibition of Candida albicans yeast growth and rescue by a diacylglycerol analogue.
Journal: Yeast (Chichester, England) 20070801
Title: Farnesol, a common sesquiterpene, inhibits PQS production in Pseudomonas aeruginosa.
Journal: Molecular microbiology 20070801
Title: Neuroprotective effects of the Ras inhibitor S-trans-trans-farnesylthiosalicylic acid, measured by diffusion-weighted imaging after traumatic brain injury in rats.
Journal: Journal of neurotrauma 20070801
Title: Arabidopsis thaliana plants possess a specific farnesylcysteine lyase that is involved in detoxification and recycling of farnesylcysteine.
Journal: The Plant journal : for cell and molecular biology 20070601
Title: The rice (E)-beta-caryophyllene synthase (OsTPS3) accounts for the major inducible volatile sesquiterpenes.
Journal: Phytochemistry 20070601
Title: Suppression of lung cancer tumor growth in a nude mouse model by the Ras inhibitor salirasib (farnesylthiosalicylic acid).
Journal: Molecular cancer therapeutics 20070601
Title: The tumor suppressor neurofibromin confers sensitivity to apoptosis by Ras-dependent and Ras-independent pathways.
Journal: Cell death and differentiation 20070501
Title: The effect of terpene concentrations on the skin penetration of diclofenac sodium.
Journal: International journal of pharmaceutics 20070420
Title: Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid).
Journal: Cancer research 20070401
Title: Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.
Journal: The Journal of pharmacology and experimental therapeutics 20070301
Title: Circadian rhythms in Neurospora crassa: clock mutant effects in the absence of a frq-based oscillator.
Journal: Genetics 20070301
Title: Sesquiterpene farnesol inhibits recycling of the C55 lipid carrier of the murein monomer precursor contributing to increased susceptibility to beta-lactams in methicillin-resistant Staphylococcus aureus.
Journal: The Journal of antimicrobial chemotherapy 20070301
Title: In vivo and in vitro anaerobic mating in Candida albicans.
Journal: Eukaryotic cell 20070301
Title: A chemogenomic screen in Saccharomyces cerevisiae uncovers a primary role for the mitochondria in farnesol toxicity and its regulation by the Pkc1 pathway.
Journal: The Journal of biological chemistry 20070216
Title: Effect of farnesol on Candida dubliniensis morphogenesis.
Journal: Letters in applied microbiology 20070201
Title: Evaluation of an alcohol-based surgical hand disinfectant containing a synergistic combination of farnesol and benzethonium chloride for immediate and persistent activity against resident hand flora of volunteers and with a novel in vitro pig skin model.
Journal: Infection control and hospital epidemiology 20070201
Title: Zoledronate inhibits endothelial cell adhesion, migration and survival through the suppression of multiple, prenylation-dependent signaling pathways.
Journal: Journal of thrombosis and haemostasis : JTH 20070101
Title: Angiotensin II-induced MAPK phosphorylation mediated by Ras and/or phospholipase C-dependent phosphorylations but not by protein kinase C phosphorylation in cultured rat vascular smooth muscle cells.
Journal: Pharmacology 20070101
Title: 3D-QSAR of fungal quorum-sensing inhibiting analogs of farnesol.
Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20070101
Title: Zoledronate inhibits alphavbeta3 and alphavbeta5 integrin cell surface expression in endothelial cells.
Journal: Endothelium : journal of endothelial cell research 20070101
Title: Mechanisms of acquired resistance to endocrine therapy in hormone-dependent breast cancer cells.
Journal: The Journal of steroid biochemistry and molecular biology 20070101
Title: Transcriptional changes in Candida albicans Genes by both farnesol and high cell density at an early stage of morphogenesis in N-acetyl-D-glucosamine medium.
Journal: Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20070101
Title: Inhibitory activity of 1-farnesylpyridinium on the spatial control over the assembly of cell wall polysaccharides in Schizosaccharomyces pombe.
Journal: Journal of biochemistry 20061201
Title: Effect of farnesol on Candida dubliniensis biofilm formation and fluconazole resistance.
Journal: FEMS yeast research 20061101
Title: The retinoid-X receptor ortholog, ultraspiracle, binds with nanomolar affinity to an endogenous morphogenetic ligand.
Journal: The FEBS journal 20061101
Title: Structure of the human mitochondrial monoamine oxidase B: new chemical implications for neuroprotectant drug design.
Journal: Neurology 20061010
Title: Depletion of substrates for protein prenylation increases apoptosis in human periovulatory granulosa cells.
Journal: Molecular reproduction and development 20061001
Title: Production of tyrosol by Candida albicans biofilms and its role in quorum sensing and biofilm development.
Journal: Eukaryotic cell 20061001
Title: The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060915
Title: Efficacy of an alcohol-based healthcare hand rub containing synergistic combination of farnesol and benzethonium chloride.
Journal: International journal of hygiene and environmental health 20060901
Title: Suppression of survivin expression in glioblastoma cells by the Ras inhibitor farnesylthiosalicylic acid promotes caspase-dependent apoptosis.
Journal: Molecular cancer therapeutics 20060901
Title: Ras inhibition results in growth arrest and death of androgen-dependent and androgen-independent prostate cancer cells.
Journal: Biochemical pharmacology 20060814
Title: E2F1 identified by promoter and biochemical analysis as a central target of glioblastoma cell-cycle arrest in response to Ras inhibition.
Journal: International journal of cancer 20060801
Title: Using non-mammalian hosts to study fungal virulence and host defense.
Journal: Current opinion in microbiology 20060801
Title: In vitro synergistic effect of farnesol and human gingival cells against Candida albicans.
Journal: Yeast (Chichester, England) 20060715
Title: Farnesol and geraniol chemopreventive activities during the initial phases of hepatocarcinogenesis involve similar actions on cell proliferation and DNA damage, but distinct actions on apoptosis, plasma cholesterol and HMGCoA reductase.
Journal: Carcinogenesis 20060601
Title: Microparticles developed by electrohydrodynamic atomization for the local delivery of anticancer drug to treat C6 glioma in vitro.
Journal: Biomaterials 20060601
Title: Anticancer effects of zoledronic acid against human osteosarcoma cells.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20060601
Title: Isolation and characterization of a monoamine oxidase B selective inhibitor from tobacco smoke.
Journal: Bioorganic & medicinal chemistry 20060515
Title: Functional characterization of the putative Aspergillus nidulans poly(ADP-ribose) polymerase homolog PrpA.
Journal: Genetics 20060501
Title: Farnesol prevents Fe-NTA-mediated renal oxidative stress and early tumour promotion markers in rats.
Journal: Human & experimental toxicology 20060501
Title: Farnesol induces thyroid hormone receptor (THR) beta1 but inhibits THR-mediated signaling in MCF-7 human breast cancer cells.
Journal: Biochemical and biophysical research communications 20060428
Title: Monitoring farnesol-induced toxicity in tobacco BY-2 cells with a fluorescent analog.
Journal: Archives of biochemistry and biophysics 20060415
Title: Farnesylthiosalicylic acid induces caspase activation and apoptosis in glioblastoma cells.
Journal: Cell death and differentiation 20060401
Title: Talking to themselves: autoregulation and quorum sensing in fungi.
Journal: Eukaryotic cell 20060401
Title: Farnesol restores wild-type colony morphology to 96% of Candida albicans colony morphology variants recovered following treatment with mutagens.
Journal: Genome 20060401
Title: 3-Farnesyl-2-hydroxybenzoic acid is a new anti-Helicobacter pylori compound from Piper multiplinervium.
Journal: Journal of ethnopharmacology 20060220
Title: Farnesol-induced apoptosis in Aspergillus nidulans reveals a possible mechanism for antagonistic interactions between fungi.
Journal: Molecular microbiology 20060201
Title: A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol.
Journal: Applied biochemistry and biotechnology 20060201
Title: Farnesylthiosalicylic acid: inhibition of proliferation and enhancement of apoptosis of hormone-dependent breast cancer cells.
Journal: Anti-cancer drugs 20060101
Title: Hitting Ras where it counts: Ras antagonism in the basolateral amygdala inhibits long-term fear memory.
Journal: The European journal of neuroscience 20060101
Title: Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma.
Journal: American journal of nephrology 20060101
Title: Ras antagonist inhibits growth and chemosensitizes human epithelial ovarian cancer cells.
Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
Title: Using inhibitors of prenylation to block localization and transforming activity.
Journal: Methods in enzymology 20060101
Title: Use of the Porcine Intestinal Epithelium (PIE)-Assay to analyze early stages of colonization by the human fungal pathogen Candida albicans.
Journal: Journal of basic microbiology 20060101
Title: Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha).
Journal: The Biochemical journal 20051215
Title: Farnesylthiosalicylic acid blocks mammalian target of rapamycin signaling in breast cancer cells.
Journal: International journal of cancer 20051210
Title: Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation.
Journal: Biochemical pharmacology 20051205
Title: Enhanced pathogenicity of Candida albicans pre-treated with subinhibitory concentrations of fluconazole in a mouse model of disseminated candidiasis.
Journal: The Journal of antimicrobial chemotherapy 20051201
Title: Inhibition of Ras attenuates the course of experimental autoimmune neuritis.
Journal: Journal of neuroimmunology 20051101
Title: Apigenin and tt-farnesol with fluoride effects on S. mutans biofilms and dental caries.
Journal: Journal of dental research 20051101
Title: Synthesis of farnesol isomers via a modified Wittig procedure.
Journal: Organic letters 20051027
Title: Enhanced apoptosis through farnesol inhibition of phospholipase D signal transduction.
Journal: The FEBS journal 20051001
Title: Candida albicans-conditioned medium protects yeast cells from oxidative stress: a possible link between quorum sensing and oxidative stress resistance.
Journal: Eukaryotic cell 20051001
Title: Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol.
Journal: Alcoholism, clinical and experimental research 20050901
Title: SMGA gels for the skin permeation of haloperidol.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20050818
Title: The inhibition of human mesangial cell proliferation by S-trans, trans-farnesylthiosalicylic acid.
Journal: Kidney international 20050801
Title: The effect of farnesol on amino acid incorporation by a wild-type and cell-wall variant strain of Candida albicans.
Journal: Canadian journal of microbiology 20050801
Title: Effects of farnesol on the physical properties of DMPC membranes.
Journal: Biochimica et biophysica acta 20050715
Title: Cell cycle dynamics and quorum sensing in Candida albicans chlamydospores are distinct from budding and hyphal growth.
Journal: Eukaryotic cell 20050701
Title: Release from quorum-sensing molecules triggers hyphal formation during Candida albicans resumption of growth.
Journal: Eukaryotic cell 20050701
Title: Getting at MYC through RAS.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050615
Title: Disruption of cooperation between Ras and MycN in human neuroblastoma cells promotes growth arrest.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050615
Title: A novel method to control the balance of skin microflora. Part 1. Attack on biofilm of Staphylococcus aureus without antibiotics.
Journal: Journal of dermatological science 20050601
Title: A novel method to control the balance of skin microflora Part 2. A study to assess the effect of a cream containing farnesol and xylitol on atopic dry skin.
Journal: Journal of dermatological science 20050601
Title: Biologically active fluorescent farnesol analogs.
Journal: Chemistry & biology 20050601
Title: Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors.
Journal: The Journal of biological chemistry 20050422
Title: Modulation of hepatic and renal drug metabolizing enzyme activities in rats by subchronic administration of farnesol.
Journal: Chemico-biological interactions 20050415
Title: Phenotype switching affects biofilm formation by Candida parapsilosis.
Journal: Microbiology (Reading, England) 20050401
Title: Patch testing with a new fragrance mix detects additional patients sensitive to perfumes and missed by the current fragrance mix.
Journal: Contact dermatitis 20050401
Title: Patch testing with a new fragrance mix - reactivity to the individual constituents and chemical detection in relevant cosmetic products.
Journal: Contact dermatitis 20050401
Title: Substrate and product specificities of cis-type undecaprenyl pyrophosphate synthase.
Journal: The Biochemical journal 20050215
Title: Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death.
Journal: Cancer research 20050201
Title: Cytochrome P450 expression and activities in human tongue cells and their modulation by green tea extract.
Journal: Toxicology and applied pharmacology 20050115
Title: Lipid-mediated, reversible misfolding of a sterol-sensing domain protein.
Journal: The EMBO journal 20050112
Title: Farnesylthiosalicylic acid inhibits mammalian target of rapamycin (mTOR) activity both in cells and in vitro by promoting dissociation of the mTOR-raptor complex.
Journal: Molecular endocrinology (Baltimore, Md.) 20050101
Title: Characterization of the regulation and functional consequences of p21ras activation in neutrophils by antineutrophil cytoplasm antibodies.
Journal: Journal of the American Society of Nephrology : JASN 20050101
Title: Partial morphological and functional characterization of the corpus allatum-corpus cardiacum complex from the two-spotted stinkbug, Perillus bioculatus (Hemiptera: Pentatomidae).
Journal: In vitro cellular & developmental biology. Animal 20050101
Title: Farnesol and geranylgeraniol modulate the structural properties of phosphatidylethanolamine model membranes.
Journal: Molecular membrane biology 20050101
Title: Antiphospholipid antibodies, thrombin and LPS activate brain endothelial cells and Ras-dependent pathways through distinct mechanisms.
Journal: Immunobiology 20050101
Title: Alleviation of free radical mediated oxidative and genotoxic effects of cadmium by farnesol in Swiss albino mice.
Journal: Redox report : communications in free radical research 20050101
Title: Farnesol is glucuronidated in human liver, kidney and intestine in vitro, and is a novel substrate for UGT2B7 and UGT1A1.
Journal: The Biochemical journal 20041215
Title: A Pseudomonas aeruginosa quorum-sensing molecule influences Candida albicans morphology.
Journal: Molecular microbiology 20041201
Title: Alternative farnesoid structures induce different conformational outcomes upon the Drosophila ortholog of the retinoid X receptor, ultraspiracle.
Journal: Insect biochemistry and molecular biology 20041101
Title: Likonides A and B: new ansa farnesyl quinols from the marine sponge Hyatella sp.
Journal: Organic letters 20041028
Title: Activated H-Ras regulates hematopoietic cell survival by modulating Survivin.
Journal: Biochemical and biophysical research communications 20041015
Title: Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro.
Journal: The British journal of dermatology 20041001
Title: The antibacterial effects of terpene alcohols on Staphylococcus aureus and their mode of action.
Journal: FEMS microbiology letters 20040815
Title: The c-Raf inhibitor GW5074 provides neuroprotection in vitro and in an animal model of neurodegeneration through a MEK-ERK and Akt-independent mechanism.
Journal: Journal of neurochemistry 20040801
Title: Treatment of thioacetamide-induced liver cirrhosis by the Ras antagonist, farnesylthiosalicylic acid.
Journal: Journal of hepatology 20040801
Title: The two-component signal transduction protein Chk1p regulates quorum sensing in Candida albicans.
Journal: Eukaryotic cell 20040801
Title: Lysine beta311 of protein geranylgeranyltransferase type I partially replaces magnesium.
Journal: The Journal of biological chemistry 20040716
Title: Omega-hydroxylation of farnesol by mammalian cytochromes p450.
Journal: Biochimica et biophysica acta 20040601
Title: Absolute configuration of chiral terpenes in marking pheromones of bumblebees and cuckoo bumblebees.
Journal: Chirality 20040505
Title: Farnesol, a morphogenetic autoregulatory substance in the dimorphic fungus Candida albicans, inhibits hyphae growth through suppression of a mitogen-activated protein kinase cascade.
Journal: Biological & pharmaceutical bulletin 20040501
Title: Farnesol-DMPC phase behaviour: a (2)H-NMR study.
Journal: Biochimica et biophysica acta 20040309
Title: The novel Ras antagonist, farnesylthiosalicylate, suppresses growth of prostate cancer in vitro.
Journal: The Prostate 20040301
Title: Host plant volatiles synergize response to sex pheromone in codling moth, Cydia pomonella.
Journal: Journal of chemical ecology 20040301
Title: Contact allergy to farnesol in 2021 consecutively patch tested patients. Results of the IVDK.
Journal: Contact dermatitis 20040301
Title: Chimeragenesis of the fatty acid binding site of cytochrome P450BM3. Replacement of residues 73-84 with the homologous residues from the insect cytochrome P450 CYP4C7.
Journal: Biochemistry 20040224
Title: Restoration of sensitivity to anoikis in Ras-transformed rat intestinal epithelial cells by a Ras inhibitor.
Journal: Cell death and differentiation 20040201
Title: Inhibition of intimal thickening in the rat carotid artery injury model by a nontoxic Ras inhibitor.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040201
Title: Germ cell migration in zebrafish is dependent on HMGCoA reductase activity and prenylation.
Journal: Developmental cell 20040201
Title: Statins upregulate CD36 expression in human monocytes, an effect strengthened when combined with PPAR-gamma ligands Putative contribution of Rho GTPases in statin-induced CD36 expression.
Journal: Biochemical pharmacology 20040115
Title: Lipid metabolism in zebrafish.
Journal: Methods in cell biology 20040101
Title: Farnesyl-O-acetylhydroquinone and geranyl-O-acetylhydroquinone suppress the proliferation of murine B16 melanoma cells, human prostate and colon adenocarcinoma cells, human lung carcinoma cells, and human leukemia cells.
Journal: Cancer letters 20031230
Title: Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol.
Journal: The Journal of biological chemistry 20031226
Title: Studies on G-protein alpha.betagamma heterotrimer formation reveal a putative S-prenyl-binding site in the alpha subunit.
Journal: The Biochemical journal 20031201
Title: Increase in peripheral benzodiazepine receptors and loss of glutamate NMDA receptors in a mouse model of closed head injury: a quantitative autoradiographic study.
Journal: NeuroImage 20031201
Title: Inhibition of Streptococcus mutans biofilm accumulation and polysaccharide production by apigenin and tt-farnesol.
Journal: The Journal of antimicrobial chemotherapy 20031101
Title: New polyoxygenated farnesylcyclohexenones, deacetoxyyanuthone A and its hydro derivative from the marine-derived fungus Penicillium sp.
Journal: Journal of natural products 20031101
Title: Protein farnesyltransferase inhibitors interfere with farnesyl diphosphate binding by rubber transferase.
Journal: European journal of biochemistry 20031001
Title: Role of cholesterol-enriched diet and the mevalonate pathway in cardiac nitric oxide synthesis.
Journal: Basic research in cardiology 20030901
Title: Circadian rhythms in Neurospora crassa: farnesol or geraniol allow expression of rhythmicity in the otherwise arrhythmic strains frq10, wc-1, and wc-2.
Journal: Journal of biological rhythms 20030801
Title: Quorum sensing in Candida albicans: probing farnesol's mode of action with 40 natural and synthetic farnesol analogs.
Journal: Chemistry & biology 20030801
Title: Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway.
Journal: Cellular signalling 20030701
Title: Inhibition of mevalonate pathway is involved in alendronate-induced cell growth inhibition, but not in cytokine secretion from macrophages in vitro.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030701
Title: Isoprenoid alcohols restore protein isoprenylation in a time-dependent manner independent of protein synthesis.
Journal: Lipids 20030701
Title: Detection of farnesyl diphosphate accumulation in yeast ERG9 mutants.
Journal: Analytical biochemistry 20030615
Title: The inhibition of degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase by sterol regulatory element binding protein cleavage-activating protein requires four phenylalanine residues in span 6 of HMG-CoA reductase transmembrane domain.
Journal: Archives of biochemistry and biophysics 20030615
Title: Farnesyl transferase inhibitor SCH66336 is cytostatic, pro-apoptotic and enhances chemosensitivity to cisplatin in melanoma cells.
Journal: International journal of cancer 20030610
Title: Juvenile hormone biosynthesis in moths: synthesis and evaluation of farnesol homologs as alternate substrates of farnesol oxidase.
Journal: Insect biochemistry and molecular biology 20030601
Title: New approaches to the understanding of tamoxifen action and resistance.
Journal: Endocrine-related cancer 20030601
Title: The Ras inhibitor S-trans, trans-farnesylthiosalicylic acid exerts long-lasting neuroprotection in a mouse closed head injury model.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030601
Title: Isoprenoid biosynthesis in hereditary periodic fever syndromes and inflammation.
Journal: Cellular and molecular life sciences : CMLS 20030601
Title: The adenosine inhibition of glutamate exocytosis in synaptosomes is removed by the collapse of the vesicle-cytosol deltapH plus the opening of farnesol-sensitive Ca(2+) channels.
Journal: Cell calcium 20030401
Title: Ras antagonist farnesylthiosalicylic acid (FTS) reduces glomerular cellular proliferation and macrophage number in rat thy-1 nephritis.
Journal: Journal of the American Society of Nephrology : JASN 20030401
Title: Identification of pheromones and optimization of bait composition for click beetle pests (Coleoptera: Elateridae) in Central and Western Europe.
Journal: Pest management science 20030401
Title: Farnesylamine from the ant Monomorium fieldi Forel.
Journal: Journal of natural products 20030301
Title: Regulation of isoprenoid/cholesterol biosynthesis in cells from mevalonate kinase-deficient patients.
Journal: The Journal of biological chemistry 20030221
Title: Effects of risedronate, alendronate, and etidronate on the viability and activity of rat bone marrow stromal cells in vitro.
Journal: Calcified tissue international 20030201
Title: Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes.
Journal: Journal of lipid research 20030101
Title: Farnesyl thiosalicylic acid chemosensitizes human melanoma in vivo.
Journal: The Journal of investigative dermatology 20030101
Title: Inhibition of ras by farnesylthiosalicylate significantly reduces the levels of autoantibodies in two animal models of the antiphospholipid syndrome.
Journal: Immunobiology 20030101
Title: Farnesol for aerosol inhalation: nebulization and activity against human lung cancer cells.
Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20030101
Title: Chemical ecology of oribatid mites III. Chemical composition of oil gland exudates from two oribatid mites, Trhypochthoniellus sp. and Trhypochthonius japonicus (Acari: Trhypochthoniidae).
Journal: Experimental & applied acarology 20030101
Title: Evidence for the presence of the Kennedy and Bremer- Greenberg pathways in Caenorhabditis elegans.
Journal: Acta biochimica Polonica 20030101
Title: The maize gene terpene synthase 1 encodes a sesquiterpene synthase catalyzing the formation of (E)-beta-farnesene, (E)-nerolidol, and (E,E)-farnesol after herbivore damage.
Journal: Plant physiology 20021201
Title: Effects of apigenin and tt-farnesol on glucosyltransferase activity, biofilm viability and caries development in rats.
Journal: Oral microbiology and immunology 20021201
Title: Antifeedant effects of marine halogenated monoterpenes.
Journal: Journal of agricultural and food chemistry 20021120
Title: Protein farnesyltransferase and protein prenylation in Plasmodium falciparum.
Journal: The Journal of biological chemistry 20021101
Title: Evidence for Ras-dependent signal transduction in phenytoin teratogenicity.
Journal: Toxicology and applied pharmacology 20021101
Title: Treatment of the chronic inflammation in peripheral target tissue improves the crushed nerve recovery in the rat: histopathological assessment of the nerve recovery.
Journal: Journal of the neurological sciences 20021015
Title: Lack of isoprenoid products raises ex vivo interleukin-1beta secretion in hyperimmunoglobulinemia D and periodic fever syndrome.
Journal: Arthritis and rheumatism 20021001
Title: Solution- and solid-phase synthesis of the polybasic lipid-modified C termini of Rho A and K-Ras 4B.
Journal: Chembiochem : a European journal of chemical biology 20020902
Title: African elephant sesquiterpenes. II. Identification and synthesis of new derivatives of 2,3-dihydrofarnesol.
Journal: Journal of natural products 20020901
Title: TGFbeta regulates the expression of G alpha(i2) via an effect on the localization of ras.
Journal: Journal of molecular and cellular cardiology 20020901
Title: Alpha-phosphono lactone analogues of farnesyl pyrophosphate: an asymmetric synthesis via ring-closing metathesis.
Journal: The Journal of organic chemistry 20020809
Title: Effect of novel modulators of protein kinase C activity upon chemotherapy-induced differentiation and apoptosis in myeloid leukemic cells.
Journal: Anti-cancer drugs 20020801
Title: Actions of farnesol and xylitol against Staphylococcus aureus.
Journal: Chemotherapy 20020701
Title: Functional inhibition of Ras by S-trans,trans-farnesyl thiosalicylic acid attenuates atherosclerosis in apolipoprotein E knockout mice.
Journal: Circulation 20020521
Title: Farnesol as an inhibitor and substrate for rabbit liver microsomal P450 enzymes.
Journal: Biochemical and biophysical research communications 20020426
Title: Effects of allatotropin and allatostatin on in vitro production of juvenile hormones by the corpora allata of virgin females of the moths of Heliothis virescens and Manduca sexta.
Journal: Peptides 20020401
Title: Farnesyl thiosalicylic acid inhibits the growth of melanoma cells through a combination of cytostatic and pro-apoptotic effects.
Journal: International journal of cancer 20020401
Title: Evaluation of morphogenic regulatory activity of farnesoic acid and its derivatives against Candida albicans dimorphism.
Journal: Bioorganic & medicinal chemistry letters 20020325
Title: A general stereocontrolled, convergent synthesis of oligoprenols that parallels the biosynthetic pathway.
Journal: Journal of the American Chemical Society 20020320
Title: Farnesylpyridinium, an analog of isoprenoid farnesol, induces apoptosis but suppresses apoptotic body formation in human promyelocytic leukemia cells.
Journal: FEBS letters 20020313
Title: Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes.
Journal: FEBS letters 20020313
Title: The Ras inhibitor S-trans,trans-farnesylthiosalicylic acid chemosensitizes human tumor cells without causing resistance.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020201
Title: Farnesol and geranylgeraniol: prevention and reversion of lovastatin-induced effects in NIH3T3 cells.
Journal: Lipids 20020201
Title: Fibrate and statin synergistically increase the transcriptional activities of PPARalpha/RXRalpha and decrease the transactivation of NFkappaB.
Journal: Biochemical and biophysical research communications 20020111
Title: [Oleylamine (long-chain fatty amine)-induced cell death through MAP kinase pathways in human pancreatic cancer cells].
Journal: [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20020101
Title: Phospholipid synthesis, diacylglycerol compartmentation, and apoptosis.
Journal: Biological research 20020101
Title: Chemopreventive effect of farnesol and lanosterol on colon carcinogenesis.
Journal: Cancer detection and prevention 20020101
Title: Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention.
Journal: Anticancer research 20020101
Title: Treatment of MRL/lpr mice, a genetic autoimmune model, with the Ras inhibitor, farnesylthiosalicylate (FTS).
Journal: Clinical and experimental immunology 20011201
Title: Impairment by lovastatin of neural relaxation of the rabbit sphincter of Oddi.
Journal: European journal of pharmacology 20011130
Title: The Ras-pathway inhibitor, S-trans-trans-farnesylthiosalicylic acid, suppresses experimental allergic encephalomyelitis.
Journal: Journal of neuroimmunology 20011101
Title: Inhibition effect of new farnesol derivatives on all-trans-retinoic acid metabolism.
Journal: Metabolism: clinical and experimental 20011101
Title: Antimycobacterial plant terpenoids.
Journal: Planta medica 20011101
Title: Requirement of c-jun N-terminal kinase for apoptotic cell death induced by farnesyltransferase inhibitor, farnesylamine, in human pancreatic cancer cells.
Journal: Biochemical and biophysical research communications 20011019
Title: (+)-epi-Alpha-bisabolol [correction of bisbolol] is the wound-healing principle of Peperomia galioides: investigation of the in vivo wound-healing activity of related terpenoids.
Journal: Journal of natural products 20011001
Title: Role of G proteins and modulation of p38 MAPK activation in the protection by nitric oxide against ischemia-reoxygenation injury.
Journal: Biochemical and biophysical research communications 20010907
Title: Effect of perillic acid, a putative isoprenylation inhibitor, on the cultured rat lens.
Journal: Experimental eye research 20010801
Title: Partial characterization of farnesyl and geranylgeranyl diphosphatases induced in rice seedlings by UV-C irradiation.
Journal: Plant & cell physiology 20010801
Title: Uncoupling farnesol-induced apoptosis from its inhibition of phosphatidylcholine synthesis.
Journal: The Journal of biological chemistry 20010706
Title: Glutaredoxin protects cerebellar granule neurons from dopamine-induced apoptosis by dual activation of the ras-phosphoinositide 3-kinase and jun n-terminal kinase pathways.
Journal: The Journal of biological chemistry 20010615
Title: Role of the ERK pathway in the activation of store-mediated calcium entry in human platelets.
Journal: The Journal of biological chemistry 20010511
Title: Stereochemical analysis of the reaction catalyzed by human protein geranylgeranyl transferase.
Journal: Biochemistry 20010403
Title: Farnesol oxidation in insects: evidence that the biosynthesis of insect juvenile hormone is mediated by a specific alcohol oxidase.
Journal: Insect biochemistry and molecular biology 20010201
Title: Lysosomal prenylcysteine lyase is a FAD-dependent thioether oxidase.
Journal: The Journal of biological chemistry 20010126
Title: The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol.
Journal: Biochemical and biophysical research communications 20000402
Title: Farnesol is utilized for isoprenoid biosynthesis in plant cells via farnesyl pyrophosphate formed by successive monophosphorylation reactions.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19991109
Title: The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
Journal: Cancer research 19981201
Title: Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue.
Journal: Biochemistry 19981124
Title: Dislodgment and accelerated degradation of Ras.
Journal: Biochemistry 19980203
Title: Antimycobacterial activity of (E)-phytol and derivatives: a preliminary structure-activity study.
Journal: Planta medica 19980201
Title: Post-translational regulation of mevalonate kinase by intermediates of the cholesterol and nonsterol isoprene biosynthetic pathways.
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Title: N-(arylalkyl)farnesylamines: new potent squalene synthetase inhibitors.
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Title: Amidinium cation as a mimic of allylic carbocation: synthesis and squalene synthetase inhibitory activity of an amidinium analog of a carbocation intermediate.
Journal: Journal of medicinal chemistry 19930305
Title: The gamma subunit of transducin is farnesylated.
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Title: Biodegradation of acyclic isoprenoids by Pseudomonas species.
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