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10601-73-7,MFCD00178451
Catalog No.:AA009REL

10601-73-7 | N-(3-Hydroxypropyl)acetamide

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1g
95%
in stock  
$170.00   $119.00
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5g
95%
in stock  
$569.00   $398.00
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10g
95%
in stock  
$959.00   $671.00
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25g
95%
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$1,733.00   $1,213.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA009REL
Chemical Name:
N-(3-Hydroxypropyl)acetamide
CAS Number:
10601-73-7
Molecular Formula:
C5H11NO2
Molecular Weight:
117.1463
MDL Number:
MFCD00178451
SMILES:
CC(=O)NCCCO
Properties
Computed Properties
 
Complexity:
72.8  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
-0.8  

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,1978,vol.21,p.746-753

[1]Kim,JhongK.;Souma,Yoshie;Beutow,Norman;Ibbeson,Chris;Caserio,MarjorieC.[JournalofOrganicChemistry,1989,vol.54,#7,p.1714-1720]

[2]CurrentPatentAssignee:PFIZERINC-US6340687,2002,B1Locationinpatent:Example3

[3]Locationinpatent:experimentalpartChintareddy,VenkatReddy;Ho,Hung-An;Sadow,AaronD.;Verkade,JohnG.[TetrahedronLetters,2011,vol.52,#49,p.6523-6529]

[1]Fernandez;Menendez;Gotor[Synthesis,1991,#9,p.713-716]

[1]CurrentPatentAssignee:KAIST-US2018/66011,2018,A1Locationinpatent:Paragraph0099-0101

[2]Dendrinos,Kleanthis;Jeong,Jeannie;Huang,Wei;Kalivretenos,AristotleG.[ChemicalCommunications,1998,#4,p.499-500]

[3]Yadav,VeejendraK.;Babu,K.Ganesh[JournalofOrganicChemistry,2004,vol.69,#2,p.577-580]

[4]Locationinpatent:schemeortableSuzuki,Takao;Moriya,Minoru;Sakamoto,Toshihiro;Suga,Takuya;Kishino,Hiroyuki;Takahashi,Hidekazu;Ishikawa,Makoto;Nagai,Keita;Imai,Yumiko;Sekino,Etsuko;Ito,Masahiko;Iwaasa,Hisashi;Ishihara,Akane;Tokita,Shigeru;Kanatani,Akio;Sato,Nagaaki;Fukami,Takehiro[BioorganicandMedicinalChemistryLetters,2009,vol.19,#11,p.3072-3077]

[5]Vokkaliga,Smitha;Jeong,Jeannie;Lacourse,WilliamR.;Kalivretenos,Aristotle[TetrahedronLetters,2011,vol.52,#21,p.2722-2724]

[1]CurrentPatentAssignee:PFIZERINC-US6340687,2002,B1Locationinpatent:Example3

[2]Locationinpatent:schemeortableSuzuki,Takao;Moriya,Minoru;Sakamoto,Toshihiro;Suga,Takuya;Kishino,Hiroyuki;Takahashi,Hidekazu;Ishikawa,Makoto;Nagai,Keita;Imai,Yumiko;Sekino,Etsuko;Ito,Masahiko;Iwaasa,Hisashi;Ishihara,Akane;Tokita,Shigeru;Kanatani,Akio;Sato,Nagaaki;Fukami,Takehiro[BioorganicandMedicinalChemistryLetters,2009,vol.19,#11,p.3072-3077]

Literature

Title: Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest.

Journal: Journal of medicinal chemistry 20040701

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