106243-16-7,MFCD00083209
Catalog No.:AA0035M7

106243-16-7 | Thioperamide

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Purity
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10mg
≥99%(HPLC)
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$266.00   $187.00
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50mg
≥99%(HPLC)
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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Technical Information
Catalog Number:
AA0035M7
Chemical Name:
Thioperamide
CAS Number:
106243-16-7
Molecular Formula:
C15H24N4S
Molecular Weight:
292.4429
MDL Number:
MFCD00083209
SMILES:
S=C(N1CCC(CC1)c1cnc[nH]1)NC1CCCCC1
Properties
Computed Properties
 
Complexity:
322  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
2.4  

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,1995,vol.38,p.3342-3350

Literature

Title: Involvement of the histamine H4 receptor in clozapine-induced hematopoietic toxicity: Vulnerability under granulocytic differentiation of HL-60 cells.

Journal: Toxicology and applied pharmacology 20160901

Title: Histamine at low concentrations aggravates rat liver BRL-3A cell injury induced by hypoxia/reoxygenation through histamine H2 receptor in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20130201

Title: Proxyfan acts as a neutral antagonist of histamine H3 receptors in the feeding-related hypothalamic ventromedial nucleus.

Journal: British journal of pharmacology 20121101

Title: Histamine H4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability.

Journal: British journal of pharmacology 20121001

Title: Ophthalmic antihistamines and H1-H4 receptors.

Journal: Current opinion in allergy and clinical immunology 20121001

Title: Role of L-carnosine in the control of blood glucose, blood pressure, thermogenesis, and lipolysis by autonomic nerves in rats: involvement of the circadian clock and histamine.

Journal: Amino acids 20120701

Title: A bioinformatics search for selective histamine h4 receptor antagonists through structure-based virtual screening strategies.

Journal: Chemical biology & drug design 20120501

Title: Effects of neonatal methamphetamine and thioperamide exposure on spatial memory retention and circadian activity later in life.

Journal: Behavioural brain research 20120421

Title: Histamine reverses a memory deficit induced in rats by early postnatal maternal deprivation.

Journal: Neurobiology of learning and memory 20120101

Title: Ligand based design of novel histamine H₄ receptor antagonists; fragment optimization and analysis of binding kinetics.

Journal: Bioorganic & medicinal chemistry letters 20120101

Title: In vivo receptor occupancy assay of histamine H₃ receptor antagonist in rats using non-radiolabeled tracer.

Journal: Journal of pharmacological and toxicological methods 20120101

Title: Anti-stress effects of carnosine on restraint-evoked immunocompromise in mice through spleen lymphocyte number maintenance.

Journal: PloS one 20120101

Title: Unusual effects of nicotine as a psychostimulant on ambulatory activity in mice.

Journal: ISRN pharmacology 20120101

Title: Histamine is a modulator of metamorphic competence in Strongylocentrotus purpuratus (Echinodermata: Echinoidea).

Journal: BMC developmental biology 20120101

Title: Desipramine inhibits histamine H1 receptor-induced Ca2+ signaling in rat hypothalamic cells.

Journal: PloS one 20120101

Title: Histamine neurons in the tuberomamillary nucleus: a whole center or distinct subpopulations?

Journal: Frontiers in systems neuroscience 20120101

Title: Histamine h3 receptor: a novel therapeutic target in alcohol dependence?

Journal: Frontiers in systems neuroscience 20120101

Title: Identification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptor.

Journal: PloS one 20120101

Title: The mediation of the central histaminergic system in the pressor effect of intracerebroventricularly injected melittin, a phospholipase A2 activator, in normotensive rats.

Journal: Prostaglandins, leukotrienes, and essential fatty acids 20120101

Title: Searching for the Multi-Target-Directed Ligands against Alzheimer's disease: discovery of quinoxaline-based hybrid compounds with AChE, H₃R and BACE 1 inhibitory activities.

Journal: Bioorganic & medicinal chemistry 20111201

Title: The role of cortical and hypothalamic histamine-3 receptors in the modulation of central histamine neurotransmission: an in vivo electrophysiology and microdialysis study.

Journal: The European journal of neuroscience 20111201

Title: The hydrophobic amino acids in putative helix 8 in carboxy-terminus of histamine H(3) receptor are involved in receptor-G-protein coupling.

Journal: Cellular signalling 20111101

Title: Differential modulation of excitatory and inhibitory striatal synaptic transmission by histamine.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20111026

Title: Differential effects of histamine H(3) receptor inverse agonist thioperamide, given alone or in combination with the N-methyl-d-aspartate receptor antagonist dizocilpine, on reconsolidation and consolidation of a contextual fear memory in mice.

Journal: Neuroscience 20111013

Title: Histamine facilitates consolidation of fear extinction.

Journal: The international journal of neuropsychopharmacology 20111001

Title: In vivo electrochemical evidence for simultaneous 5-HT and histamine release in the rat substantia nigra pars reticulata following medial forebrain bundle stimulation.

Journal: Journal of neurochemistry 20110901

Title: Role of the second and third extracellular loops of the histamine H(4) receptor in receptor activation.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110901

Title: Ontogenetic serotoninergic lesioning alters histaminergic activity in rats in adulthood.

Journal: Neurotoxicity research 20110801

Title: Thioperamide, an H₃ receptor antagonist prevents [³H]glucose uptake in brain of adult rats lesioned as neonates with 5,7-dihydroxytryptamine.

Journal: Neurotoxicity research 20110701

Title: Involvement of histaminergic receptor mechanisms in the stimulation of NT-3 synthesis in astrocytes.

Journal: Neuropharmacology 20110601

Title: Prepulse inhibition of the startle reflex and response to antipsychotic treatments in two outbred mouse strains in comparison to the inbred DBA/2 mouse.

Journal: Psychopharmacology 20110601

Title: Memory facilitating effects of agomelatine in the novel object recognition memory paradigm in the rat.

Journal: Pharmacology, biochemistry, and behavior 20110601

Title: Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters.

Journal: Physiology & behavior 20110601

Title: Regulation of ERK2 phosphorylation by histamine in splenocytes.

Journal: Immunopharmacology and immunotoxicology 20110601

Title: The histamine H3 receptor: from discovery to clinical trials with pitolisant.

Journal: British journal of pharmacology 20110601

Title: Effects of histamine H3 receptors on chemical hyperalgesia in diabetic rats.

Journal: Neuropharmacology 20110501

Title: N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands.

Journal: Bioorganic & medicinal chemistry 20110501

Title: Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins.

Journal: Molecular pharmacology 20110401

Title: Newer molecules in the treatment of schizophrenia: A clinical update.

Journal: Indian journal of pharmacology 20110401

Title: Triazole ligands reveal distinct molecular features that induce histamine H4 receptor affinity and subtly govern H4/H3 subtype selectivity.

Journal: Journal of medicinal chemistry 20110324

Title: Antidiabetic properties of the histamine H3 receptor protean agonist proxyfan.

Journal: Endocrinology 20110301

Title: Skin application of urea-containing cream affected cutaneous arterial sympathetic nerve activity, blood flow, and water evaporation.

Journal: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) 20110201

Title: Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids.

Journal: Peptides 20110201

Title: [Roles of histamine in the exacerbated allergic dermatitis].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110201

Title: Histamine H3 receptor as a drug discovery target.

Journal: Journal of medicinal chemistry 20110113

Title: H3 receptors and pain modulation: peripheral, spinal, and brain interactions.

Journal: The Journal of pharmacology and experimental therapeutics 20110101

Title: Effects of antihistamines on innate immune responses to severe bacterial infection in mice.

Journal: International archives of allergy and immunology 20110101

Title: Histaminergic mechanisms for modulation of memory systems.

Journal: Neural plasticity 20110101

Title: Inverse agonism and its therapeutic significance.

Journal: Indian journal of pharmacology 20110101

Title: Thioperamide induces CD4 CD25 Foxp3 regulatory T lymphocytes in the lung mucosa of allergic mice through its action on dendritic cells.

Journal: Journal of asthma and allergy 20110101

Title: Kv4.2 mediates histamine modulation of preoptic neuron activity and body temperature.

Journal: PloS one 20110101

Title: Biological Significance of GPCR Heteromerization in the Neuro-Endocrine System.

Journal: Frontiers in endocrinology 20110101

Title: Histamine 3 receptor activation mediates inhibition of acid secretion during Helicobacter-induced gastritis.

Journal: World journal of gastrointestinal pathophysiology 20101215

Title: Microinjection of histamine into the dentate gyrus produces antinociception in the formalin test in rats.

Journal: Pharmacology, biochemistry, and behavior 20101201

Title: Comparison of the pharmacological properties of human and rat histamine H(3)-receptors.

Journal: Biochemical pharmacology 20101101

Title: Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain.

Journal: The Journal of biological chemistry 20101008

Title: Validation and pharmacological characterisation of MK-801-induced locomotor hyperactivity in BALB/C mice as an assay for detection of novel antipsychotics.

Journal: Psychopharmacology 20101001

Title: Histamine H(3) receptor modulates nociception in a rat model of cholestasis.

Journal: Pharmacology, biochemistry, and behavior 20100901

Title: Environmental stressors and neurobiological features of marine teleosts: histamine receptors as targets.

Journal: Critical reviews in toxicology 20100801

Title: Effect of anserine ingestion on hyperglycemia and the autonomic nerves in rats and humans.

Journal: Nutritional neuroscience 20100801

Title: Effect of combined treatment of thioperamide with some antiepileptic drugs on methionine-sulfoximine induced convulsions in mice.

Journal: Indian journal of experimental biology 20100801

Title: Histamine H3 receptor activation potentiates peripheral opioid-mediated antinociception: substance P role in peripheral inflammation in mice.

Journal: European journal of pharmacology 20100725

Title: Effect of anserine ingestion on the hyperglycemia and autonomic nerves in rats and humans.

Journal: Nutritional neuroscience 20100601

Title: Effects of sympathetic histamine on vasomotor responses of blood vessels in rabbit ear to electrical stimulation.

Journal: Neuroscience bulletin 20100601

Title: Investigation of the bioactive conformation of histamine H3 receptor antagonists by the cyclopropylic strain-based conformational restriction strategy.

Journal: Journal of medicinal chemistry 20100513

Title: Molecular determinants of ligand binding to H4R species variants.

Journal: Molecular pharmacology 20100501

Title: Impact of the DRY motif and the missing 'ionic lock' on constitutive activity and G-protein coupling of the human histamine H4 receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20100501

Title: Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists.

Journal: Bioorganic & medicinal chemistry letters 20100415

Title: Synthesis and QSAR of quinazoline sulfonamides as highly potent human histamine H4 receptor inverse agonists.

Journal: Journal of medicinal chemistry 20100325

Title: Modulation of histamine H(3) receptor function by monovalent ions.

Journal: Neuroscience letters 20100319

Title: Neuropharmacology of vestibular system disorders.

Journal: Current neuropharmacology 20100301

Title: Modeling G protein-coupled receptors for structure-based drug discovery using low-frequency normal modes for refinement of homology models: application to H3 antagonists.

Journal: Proteins 20100201

Title: Synthesis and structural and pharmacological properties of cyclopropane-based conformationally restricted analogs of 4-methylhistamine as histamine H3/H4 receptor ligands.

Journal: Bioorganic & medicinal chemistry 20100201

Title: Involvement of the histaminergic system in cytidine 5'-diphosphocholine-induced reversal of critical haemorrhagic hypotension in rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100201

Title: Effects of anserine on the renal sympathetic nerve activity and blood pressure in urethane-anesthetized rats.

Journal: Physiological research 20100101

Title: Oral L-histidine exerts antihypertensive effects via central histamine H3 receptors and decreases nitric oxide content in the rostral ventrolateral medulla in spontaneously hypertensive rats.

Journal: Clinical and experimental pharmacology & physiology 20100101

Title: Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators involved.

Journal: Toxicon : official journal of the International Society on Toxinology 20100101

Title: Pretreatment with l-histidine produces a shift from methamphetamine-induced stereotypical biting to persistent locomotion in mice.

Journal: Pharmacology, biochemistry, and behavior 20100101

Title: R-(-)-alpha-methylhistamine, a histamine H3 receptor agonist, induces endothelium-dependent vasodilation in rat mesenteric resistance arteries.

Journal: Biological & pharmaceutical bulletin 20100101

Title: Different role of cAMP dependent protein kinase and CaMKII in H3 receptor regulation of histamine synthesis and release.

Journal: Neuroscience 20091215

Title: The effects of thioperamide on extracellular levels of glutamate and GABA in the rat prefrontal cortex.

Journal: Psychopharmacology 20091201

Title: Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.

Journal: European journal of medicinal chemistry 20091101

Title: Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor.

Journal: Molecular pharmacology 20091101

Title: Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H4 receptor agonists.

Journal: Journal of medicinal chemistry 20091022

Title: 2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.

Journal: Bioorganic & medicinal chemistry 20091015

Title: Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines.

Journal: European journal of medicinal chemistry 20091001

Title: Effects of the H(3) antagonist, thioperamide, on behavioral alterations induced by systemic MK-801 administration in rats.

Journal: Psychopharmacology 20090901

Title: Enhanced morphine-induced antinociception in histamine H3 receptor gene knockout mice.

Journal: Neuropharmacology 20090901

Title: Anxiolytic-like profiles of histamine H3 receptor agonists in animal models of anxiety: a comparative study with antidepressants and benzodiazepine anxiolytic.

Journal: Psychopharmacology 20090801

Title: Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.

Journal: Bioorganic & medicinal chemistry letters 20090801

Title: JNJ-10181457, a selective non-imidazole histamine H(3) receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition.

Journal: Neuropharmacology 20090601

Title: Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies.

Journal: Bioorganic & medicinal chemistry 20090601

Title: Heterogeneity of histaminergic neurons in the tuberomammillary nucleus of the rat.

Journal: The European journal of neuroscience 20090601

Title: N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.

Journal: Journal of medicinal chemistry 20090423

Title: Non-imidazole histamine H3 ligands, part IV: SAR of 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives.

Journal: European journal of medicinal chemistry 20090401

Title: Characterization of histamine-induced relaxation in pre-contracted rat aorta.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090401

Title: Histaminergic activity in a rodent model of Parkinson's disease.

Journal: Neurotoxicity research 20090401

Title: Effects of the H3 receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions.

Journal: Psychopharmacology 20090301

Title: The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster.

Journal: Behavioural pharmacology 20090301

Title: High constitutive activity and a G-protein-independent high-affinity state of the human histamine H(4)-receptor.

Journal: Biochemistry 20090217

Title: Autonomic and cardiovascular effects of central neuromedin U in rats.

Journal: Physiology & behavior 20090216

Title: Possible role of the histaminergic system in autonomic and cardiovascular responses to neuropeptide Y.

Journal: Neuropeptides 20090201

Title: H3 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing retrieval.

Journal: Psychopharmacology 20090101

Title: Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model.

Journal: International archives of allergy and immunology 20090101

Title: L-histidine enhances learning in stressed zebrafish.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20090101

Title: Cytokine responses of intraepithelial lymphocytes are regulated by histamine H(2) receptor.

Journal: Journal of gastroenterology 20090101

Title: A novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activation.

Journal: PloS one 20090101

Title: Alpha2 adrenoceptors modulate histamine release from sympathetic nerves in the guinea pig vas deferens.

Journal: Neuropharmacology 20090101

Title: H4 histamine receptors mediate cell cycle arrest in growth factor-induced murine and human hematopoietic progenitor cells.

Journal: PloS one 20090101

Title: Modulatory effects of histamine on cat carotid body chemoreception.

Journal: Respiratory physiology & neurobiology 20081231

Title: Discovery of quinazolines as histamine H4 receptor inverse agonists using a scaffold hopping approach.

Journal: Journal of medicinal chemistry 20081225

Title: Role of histamine in short- and long-term effects of methamphetamine on the developing mouse brain.

Journal: Journal of neurochemistry 20081101

Title: Biphasic effects of orexin-A on autonomic nerve activity and lipolysis.

Journal: Neuroscience letters 20081024

Title: Effect of thioperamide on oxidative stress markers in middle cerebral artery occlusion model of focal cerebral ischemia in rats.

Journal: Human & experimental toxicology 20081001

Title: The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.

Journal: Journal of medicinal chemistry 20080911

Title: Electrophysiology-based analysis of human histamine H(4) receptor pharmacology using GIRK channel coupling in Xenopus oocytes.

Journal: European journal of pharmacology 20080904

Title: Localization and function of histamine H3 receptor in the nasal mucosa.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20080901

Title: Alleviation of ischemia-induced brain edema by activation of the central histaminergic system in rats.

Journal: Journal of pharmacological sciences 20080901

Title: Regulation of sympathetic nerve activity by L-carnosine in mammalian white adipose tissue.

Journal: Neuroscience letters 20080815

Title: Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.

Journal: Journal of medicinal chemistry 20080612

Title: Correlation between ex vivo receptor occupancy and wake-promoting activity of selective H3 receptor antagonists.

Journal: The Journal of pharmacology and experimental therapeutics 20080601

Title: Blocking histamine H(1) improves learning and mnemonic dysfunction in mice with social isolation plus repeated methamphetamine injection.

Journal: Journal of pharmacological sciences 20080601

Title: Zebrafish: An in vivo model for the study of neurological diseases.

Journal: Neuropsychiatric disease and treatment 20080601

Title: Narcolepsy: current treatment options and future approaches.

Journal: Neuropsychiatric disease and treatment 20080601

Title: Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function.

Journal: Neuropharmacology 20080516

Title: Fragment based design of new H4 receptor-ligands with anti-inflammatory properties in vivo.

Journal: Journal of medicinal chemistry 20080424

Title: Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses.

Journal: The Journal of biological chemistry 20080418

Title: Role of histamine in brain protection in surgical brain injury in mice.

Journal: Brain research 20080418

Title: Effects of oolong tea on renal sympathetic nerve activity and spontaneous hypertension in rats.

Journal: Metabolism: clinical and experimental 20080401

Title: Ontogenetic noradrenergic lesion alters histaminergic activity in adult rats.

Journal: Neurotoxicity research 20080401

Title: Specific cerebral heat shock proteins and histamine receptor cross-talking mechanisms promote distinct lead-dependent neurotoxic responses in teleosts.

Journal: Toxicology and applied pharmacology 20080301

Title: Comparative effects of olanzapine and ziprasidone on hypophagia induced by enhanced histamine neurotransmission in the rat.

Journal: Behavioural pharmacology 20080301

Title: Carnosine protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells.

Journal: Cellular and molecular neurobiology 20080201

Title: Effects of central histamine receptors blockade on GABA(A) agonist-induced food intake in broiler cockerels.

Journal: Pakistan journal of biological sciences : PJBS 20080201

Title: Antigen inhalation induces mast cells and eosinophils infiltration in the guinea pig esophageal epithelium involving histamine-mediated pathway.

Journal: Life sciences 20080130

Title: Distinctive role of central histamine H3 receptor in various orexigenic pathways.

Journal: European journal of pharmacology 20080128

Title: CSF histamine levels in rats reflect the central histamine neurotransmission.

Journal: Neuroscience letters 20080117

Title: Modulation of hippocampal theta oscillation by histamine H3 receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20080101

Title: Mast cell-derived histamine mediates cystitis pain.

Journal: PloS one 20080101

Title: Histamine H(3) receptor ligands modulate L-dopa-evoked behavioral responses and L-dopa derived extracellular dopamine in dopamine-denervated rat striatum.

Journal: Neurotoxicity research 20080101

Title: Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells.

Journal: BMC pharmacology 20080101

Title: Histamine-induced itch and its relationship with pain.

Journal: Molecular pain 20080101

Title: The possible involvement of hyperpolarizing mechanisms in histamine-induced relaxation of the rat portal vein.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20080101

Title: Histamine in Macaca mulatto monkey cardiac sympathetic nerve system: a morphological and functional assessment.

Journal: Autonomic neuroscience : basic & clinical 20071230

Title: Functional expression of H4 histamine receptor in human natural killer cells, monocytes, and dendritic cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20071201

Title: The role of carcinine in signaling at the Drosophila photoreceptor synapse.

Journal: PLoS genetics 20071201

Title: Activation of peripheral and spinal histamine H3 receptors inhibits formalin-induced inflammation and nociception, respectively.

Journal: Pharmacology, biochemistry, and behavior 20071101

Title: Reduced histamine levels and H3 receptor antagonist-induced histamine release in the amygdala of Apoe-/- mice.

Journal: Journal of neurochemistry 20071001

Title: The Akt/GSK-3beta axis as a new signaling pathway of the histamine H(3) receptor.

Journal: Journal of neurochemistry 20071001

Title: Histamine improves antigen uptake and cross-presentation by dendritic cells.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070915

Title: Interaction of nicotinic and histamine H(3) systems in the radial-arm maze repeated acquisition task.

Journal: European journal of pharmacology 20070813

Title: Betahistine in the treatment of Ménière's disease.

Journal: Neuropsychiatric disease and treatment 20070801

Title: Histaminergic ligands improve vestibular compensation in the cat: behavioural, neurochemical and molecular evidence.

Journal: European journal of pharmacology 20070730

Title: Blockade of brain histamine metabolism alters methamphetamine-induced expression pattern of stereotypy in mice via histamine H1 receptors.

Journal: Neuroscience 20070713

Title: Histamine H4 receptor agonists have more activities than H4 agonism in antigen-specific human T-cell responses.

Journal: Immunology 20070601

Title: Interaction of calcitonin gene-related peptide, nitric oxide and histamine release in neurogenic blood flow and afferent activation in the rat cranial dura mater.

Journal: Cephalalgia : an international journal of headache 20070601

Title: H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway.

Journal: Laboratory investigation; a journal of technical methods and pathology 20070501

Title: Histaminergic H1 receptors mediate L-histidine-induced anxiety in elevated plus-maze test in mice.

Journal: Behavioural pharmacology 20070501

Title: Identification of zebrafish histamine H1, H2 and H3 receptors and effects of histaminergic ligands on behavior.

Journal: Biochemical pharmacology 20070415

Title: The brain H3-receptor as a novel therapeutic target for vigilance and sleep-wake disorders.

Journal: Biochemical pharmacology 20070415

Title: Auditory stimulation affects renal sympathetic nerve activity and blood pressure in rats.

Journal: Neuroscience letters 20070412

Title: Thioperamide reduces intracellular calcium in mouse brain synaptosomes.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070401

Title: Influence of the H3/H4 receptor antagonist, thioperamide on regional haemodynamics in rats with trinitrobenzene sulfonic acid-induced colitis.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20070401

Title: Thioperamide delays vestibular compensation in goldfish.

Journal: Neuroscience letters 20070326

Title: Sex- and histamine-dependent long-term cognitive effects of methamphetamine exposure.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070301

Title: Carnosine protects against NMDA-induced neurotoxicity in differentiated rat PC12 cells through carnosine-histidine-histamine pathway and H(1)/H(3) receptors.

Journal: Biochemical pharmacology 20070301

Title: Histamine affects STAT6 phosphorylation via its effects on IL-4 secretion: role of H1 receptors in the regulation of IL-4 production.

Journal: International immunopharmacology 20070301

Title: Suppression of inflammatory cell recruitment by histamine receptor stimulation in ischemic rat brains.

Journal: European journal of pharmacology 20070227

Title: Involvement of the histaminergic system in renal sympathetic and cardiovascular responses to leptin and ghrelin.

Journal: Neuroscience letters 20070208

Title: In vitro pharmacology at human histamine H3 receptors and brain access of non-imidazole alkylpiperidine derivatives.

Journal: Pharmacological research 20070201

Title: Modification of formalin-induced nociception by different histamine receptor agonists and antagonists.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20070115

Title: Role of apolipoprotein E in anxiety.

Journal: Neural plasticity 20070101

Title: Role of histamine H3 and H4 receptors in mechanical hyperalgesia following peripheral nerve injury.

Journal: Neuroimmunomodulation 20070101

Title: Histamine H3 receptor agonist- and antagonist-evoked vacuous chewing movements in 6-OHDA-lesioned rats occurs in an absence of change in microdialysate dopamine levels.

Journal: European journal of pharmacology 20061215

Title: Feeding differences in pubertal and aged golden hamsters (Mesocricetus auratus) are related to specific cerebral expression pattern of histamine subtype 3 receptor.

Journal: Behavioral neuroscience 20061201

Title: Expression of histamine receptors and effect of histamine in the rat carotid body chemoafferent pathway.

Journal: The European journal of neuroscience 20061201

Title: Mechanism of imipramine-induced seizures in amygdala-kindled rats.

Journal: Epilepsy research 20061101

Title: Renoprotective effects of l-carnosine on ischemia/reperfusion-induced renal injury in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20061101

Title: Dose-different effects of orexin-A on the renal sympathetic nerve and blood pressure in urethane-anesthetized rats.

Journal: Experimental biology and medicine (Maywood, N.J.) 20061101

Title: A comparison of protective effects between L-histidine and hypothermia against ischemia-induced neuronal damage in gerbil hippocampus.

Journal: European journal of pharmacology 20060928

Title: Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.

Journal: Journal of medicinal chemistry 20060907

Title: Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway.

Journal: Neuropharmacology 20060901

Title: Suppression of ischemia/reperfusion liver injury by histamine H4 receptor stimulation in rats.

Journal: European journal of pharmacology 20060821

Title: Homologous down-regulation of histamine H3 receptors in rat striatal slices.

Journal: Synapse (New York, N.Y.) 20060801

Title: Antipsychotic-like profile of thioperamide, a selective H3-receptor antagonist in mice.

Journal: Fundamental & clinical pharmacology 20060801

Title: Evidence for histamine as a neurotransmitter in the cardiac sympathetic nervous system.

Journal: American journal of physiology. Heart and circulatory physiology 20060701

Title: Histamine enhances inhibitory avoidance memory consolidation through a H2 receptor-dependent mechanism.

Journal: Neurobiology of learning and memory 20060701

Title: Impaired drinking response in histamine H3 receptor knockout mice following dehydration or angiotensin-II challenge.

Journal: Pharmacology, biochemistry, and behavior 20060701

Title: Increasing synaptic noradrenaline, serotonin and histamine enhances in vivo binding of phosphodiesterase-4 inhibitor (R)-[11C]rolipram in rat brain, lung and heart.

Journal: Life sciences 20060620

Title: Changes in the histaminergic system during vestibular compensation in the cat.

Journal: The Journal of physiology 20060615

Title: The effect of histamine on field-stimulated contractions of the guinea-pig prostate.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20060601

Title: Histamine-induced enhancement of vasopressin and oxytocin secretion in rat neurohypophyseal tissue cultures.

Journal: Regulatory peptides 20060515

Title: Olfactory stimulation with scent of lavender oil affects autonomic neurotransmission and blood pressure in rats.

Journal: Neuroscience letters 20060501

Title: Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives.

Journal: British journal of pharmacology 20060401

Title: Effects of the H3-receptor inverse agonist thioperamide on the psychomotor effects induced by acutely and repeatedly given cocaine in C57BL/6J mice.

Journal: Pharmacology, biochemistry, and behavior 20060401

Title: Effects of histamine H(3) antagonists and donepezil on learning and mnemonic deficits induced by pentylenetetrazol kindling in weanling mice.

Journal: Neuropharmacology 20060301

Title: Role of H1 receptors in histamine-mediated up-regulation of STAT4 phosphorylation.

Journal: International immunopharmacology 20060301

Title: Histamine protects against NMDA-induced necrosis in cultured cortical neurons through H receptor/cyclic AMP/protein kinase A and H receptor/GABA release pathways.

Journal: Journal of neurochemistry 20060301

Title: Histamine increases sickle erythrocyte adherence to endothelium.

Journal: British journal of haematology 20060201

Title: [The effect of central histamine H3 receptor on breathing activity of asthmatic guinea pigs].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20060201

Title: Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060125

Title: The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A inhibit enteric cholinergic transmission in the guinea-pig ileum.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20060101

Title: Histamine receptors influence blood-spinal cord barrier permeability, edema formation, and spinal cord blood flow following trauma to the rat spinal cord.

Journal: Acta neurochirurgica. Supplement 20060101

Title: Aversive memory reactivation engages in the amygdala only some neurotransmitters involved in consolidation.

Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20060101

Title: Reduction in brain infarction by augmentation of central histaminergic activity in rats.

Journal: Brain research 20051220

Title: Histamine (H3) receptors modulate the excitatory amino acid receptor response of the vestibular afferents.

Journal: Brain research 20051207

Title: Effects of intraduodenal injection of Lactobacillus johnsonii La1 on renal sympathetic nerve activity and blood pressure in urethane-anesthetized rats.

Journal: Neuroscience letters 20051202

Title: Mechanisms of histamine-induced relaxation in bovine small adrenal cortical arteries.

Journal: American journal of physiology. Endocrinology and metabolism 20051201

Title: Sleep disturbances, psychiatric disorders, and psychotropic drugs.

Journal: Dialogues in clinical neuroscience 20051201

Title: Some environmental contaminants influence motor and feeding behaviors in the ornate wrasse (Thalassoma pavo) via distinct cerebral histamine receptor subtypes.

Journal: Environmental health perspectives 20051101

Title: The histaminergic signaling system exerts a neuroprotective role against neurodegenerative-induced processes in the hamster.

Journal: The Journal of pharmacology and experimental therapeutics 20051001

Title: Modulation of spontaneous alternation performance of mice treated with thioperamide and tacrine in a cross maze task.

Journal: Fundamental & clinical pharmacology 20051001

Title: Effect of thioperamide on modified forced swimming test-induced oxidative stress in mice.

Journal: Basic & clinical pharmacology & toxicology 20051001

Title: Olfactory stimulation with scent of lavender oil affects autonomic nerves, lipolysis and appetite in rats.

Journal: Neuroscience letters 20050701

Title: Involvement of histamine H1 and H2 receptors in the regulation of STAT-1 phosphorylation: inverse agonism exhibited by the receptor antagonists.

Journal: International immunopharmacology 20050701

Title: Histamine excites noradrenergic neurons in locus coeruleus in rats.

Journal: Neuropharmacology 20050701

Title: Histamine-3 receptor antagonists reduce superoxide anion generation and lipid peroxidation in rat brain homogenates.

Journal: The Journal of pharmacy and pharmacology 20050601

Title: Generation of cell lines for drug discovery through random activation of gene expression: application to the human histamine H3 receptor.

Journal: Assay and drug development technologies 20050601

Title: Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs.

Journal: Brain research 20050531

Title: The H3 antagonist thioperamide reveals conditioned preference for a context associated with an inactive small dose of cocaine in C57BL/6J mice.

Journal: Behavioural brain research 20050507

Title: Effects of histamine H3 receptor antagonists in two models of spatial learning.

Journal: Behavioural brain research 20050430

Title: Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist.

Journal: The Journal of pharmacology and experimental therapeutics 20050401

Title: 4-phenoxypiperidines: potent, conformationally restricted, non-imidazole histamine H3 antagonists.

Journal: Journal of medicinal chemistry 20050324

Title: Effect of combined histamine H1 and H3 receptor blockade on cutaneous microvascular permeability elicited by compound 48/80.

Journal: Life sciences 20050304

Title: Histamine receptors that influence blockage of the normal human nasal airway.

Journal: British journal of pharmacology 20050301

Title: Assessment of pharmacology and potential anti-obesity properties of H3 receptor antagonists/inverse agonists.

Journal: Expert opinion on investigational drugs 20050301

Title: Dose-dependent effects of L-carnosine on the renal sympathetic nerve and blood pressure in urethane-anesthetized rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20050201

Title: A biochemical and pharmacological examination of Rhamphiophis oxyrhynchus (Rufous beaked snake) venom.

Journal: Toxicon : official journal of the International Society on Toxinology 20050201

Title: Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in rats.

Journal: European journal of pharmacology 20050131

Title: 4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention.

Journal: Journal of medicinal chemistry 20050113

Title: 2-(4-alkylpiperazin-1-yl)quinolines as a new class of imidazole-free histamine H3 receptor antagonists.

Journal: Journal of medicinal chemistry 20050113

Title: Histaminergic modulation of excitatory synaptic transmission in the rat basolateral amygdala.

Journal: Neuroscience 20050101

Title: Histamine-induced cyclic AMP formation in the chick hypothalamus: interaction with vasoactive intestinal peptide.

Journal: Pharmacological reports : PR 20050101

Title: [Participation of cyclic nucleotides and phospholipidis in signal transduction of histamin receptor H3 of the gastric mucosa parietal cells in rats with experimental ulcer].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20050101

Title: Role of histaminergic neurons in development of epileptic seizures in EL mice.

Journal: Brain research. Molecular brain research 20041206

Title: Unusual functional properties of homo- and heteromultimeric histamine-gated chloride channels of Drosophila melanogaster: spontaneous currents and dual gating by GABA and histamine.

Journal: Neuroscience letters 20041130

Title: Pharmacological effects of carcinine on histaminergic neurons in the brain.

Journal: British journal of pharmacology 20041101

Title: Medicinal chemical and pharmacological aspects of imidazole-containing histamine H3 receptor antagonists.

Journal: Mini reviews in medicinal chemistry 20041101

Title: Role of the histamine system in nefopam-induced antinociception in mice.

Journal: European journal of pharmacology 20041025

Title: Histamine H3 receptors inhibit serotonin release in substantia nigra pars reticulata.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20041006

Title: Intranigral injection of the H3 agonist immepip and systemic apomorphine elicit ipsilateral turning behaviour in naive rats, but reduce contralateral turning in hemiparkinsonian rats.

Journal: Behavioural brain research 20041005

Title: The in vitro and in vivo pharmacological activity of Boiga dendrophila (mangrove catsnake) venom.

Journal: Autonomic & autacoid pharmacology 20041001

Title: Histamine H3 antagonist thioperamide dose-dependently enhances memory consolidation and reverses amnesia induced by dizocilpine or scopolamine in a one-trial inhibitory avoidance task in mice.

Journal: Behavioural brain research 20040923

Title: Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist.

Journal: Biochemical pharmacology 20040901

Title: Cloning and expression of the mouse histamine H3 receptor: evidence for multiple isoforms.

Journal: Journal of neurochemistry 20040901

Title: Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan.

Journal: Behavioural brain research 20040812

Title: Liver-expressed chemokine/CC chemokine ligand 16 attracts eosinophils by interacting with histamine H4 receptor.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20040801

Title: Histamine H3 receptor activation inhibits dopamine D1 receptor-induced cAMP accumulation in rat striatal slices.

Journal: Neuroscience letters 20040708

Title: Critical role of L-selectin and histamine H4 receptor in zymosan-induced neutrophil recruitment from the bone marrow: comparison with carrageenan.

Journal: The Journal of pharmacology and experimental therapeutics 20040701

Title: Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.

Journal: Journal of medicinal chemistry 20040603

Title: Central H3R activation by thioperamide does not affect energy balance.

Journal: Pharmacology, biochemistry, and behavior 20040601

Title: 1-alkyl-4-acylpiperazines as a new class of imidazole-free histamine H(3) receptor antagonists.

Journal: Journal of medicinal chemistry 20040520

Title: 4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.

Journal: Journal of medicinal chemistry 20040506

Title: Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice.

Journal: British journal of pharmacology 20040501

Title: Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation.

Journal: British journal of pharmacology 20040501

Title: Intracerebroventricular administration of histamine H3 receptor antagonists decreases seizures in rat models of epilepsia.

Journal: Methods and findings in experimental and clinical pharmacology 20040501

Title: Histamine h3 receptor antagonists potentiate methamphetamine self-administration and methamphetamine-induced accumbal dopamine release.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040401

Title: Inhibitory effect of iodophenpropit, a selective histamine H3 antagonist, on amygdaloid kindled seizures.

Journal: Brain research bulletin 20040315

Title: Pruritus-associated response mediated by cutaneous histamine H3 receptors.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040301

Title: Thioperamide-elicited increase of histamine release from basolateral amygdala of freely moving rats and its therapeutic implications.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040301

Title: Role of histamine H3 receptors during ischemia/reperfusion in isolated rat hearts.

Journal: Journal of cardiovascular pharmacology 20040301

Title: Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat.

Journal: BMC neuroscience 20040101

Title: Critical role of histamine H4 receptor in leukotriene B4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo.

Journal: The Journal of pharmacology and experimental therapeutics 20031201

Title: Role of histamine receptors in the regulation of edema and circulation postburn.

Journal: Burns : journal of the International Society for Burn Injuries 20031201

Title: Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor.

Journal: British journal of pharmacology 20031101

Title: Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves.

Journal: Experimental biology and medicine (Maywood, N.J.) 20031101

Title: Generation and characterization of highly constitutive active histamine H3 receptors.

Journal: The Journal of pharmacology and experimental therapeutics 20031001

Title: Aminergic control of high-frequency (approximately 200 Hz) network oscillations in the hippocampus of the behaving rat.

Journal: Neuroscience letters 20030911

Title: The first potent and selective non-imidazole human histamine H4 receptor antagonists.

Journal: Journal of medicinal chemistry 20030911

Title: Central endogenous histamine modulates sympathetic outflow through H3 receptors in the conscious rabbit.

Journal: British journal of pharmacology 20030701

Title: Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine.

Journal: Bioorganic & medicinal chemistry letters 20030616

Title: Antinociceptive mechanisms of orally administered decursinol in the mouse.

Journal: Life sciences 20030613

Title: Activation of spinal histamine H3 receptors inhibits mechanical nociception.

Journal: European journal of pharmacology 20030606

Title: Two novel and selective nonimidazole H3 receptor antagonists A-304121 and A-317920: II. In vivo behavioral and neurophysiological characterization.

Journal: The Journal of pharmacology and experimental therapeutics 20030601

Title: Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.

Journal: The Journal of pharmacology and experimental therapeutics 20030601

Title: Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells.

Journal: The Journal of pharmacology and experimental therapeutics 20030601

Title: H3 receptor blockade by thioperamide enhances cognition in rats without inducing locomotor sensitization.

Journal: Psychopharmacology 20030601

Title: Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.

Journal: Journal of medicinal chemistry 20030508

Title: Regulation by prostaglandin E2 and histamine of angiogenesis in inflammatory granulation tissue.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030501

Title: Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.

Journal: Journal of medicinal chemistry 20030410

Title: Histamine inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production in an intercellular adhesion molecule-1- and B7.1-dependent manner.

Journal: The Journal of pharmacology and experimental therapeutics 20030201

Title: Histaminergic modulation of the intact respiratory network of adult mice.

Journal: Pflugers Archiv : European journal of physiology 20030201

Title: Histamine-induced chloride secretion is mediated via H2-receptors in the pig proximal colon.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030201

Title: Neuroimmune interactions in guinea pig stomach and small intestine.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030101

Title: Functional identification of epithelial and smooth muscle histamine-dependent relaxing mechanisms in the bovine trachea, but not in bronchi.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030101

Title: Replacement of imidazole by a piperidine moiety differentially affects the potency of histamine H3-receptor antagonists.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20030101

Title: High-frequency oscillation in the hippocampus of the behaving rat and its modulation by the histaminergic system.

Journal: Hippocampus 20030101

Title: Contribution of the histaminergic receptor subtypes to histamine-induced cerebellar granular neurotoxicity.

Journal: Polish journal of pharmacology 20030101

Title: Targeted disruption of H3 receptors results in changes in brain histamine tone leading to an obese phenotype.

Journal: The Journal of clinical investigation 20021215

Title: Novel human histamine H(3) receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20021118

Title: Coordination of histamine H3 receptor antagonists with human adrenal cytochrome P450 enzymes.

Journal: Pharmacology 20021101

Title: Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.

Journal: British journal of pharmacology 20021101

Title: Endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats--studies with histamine N-methyltransferase inhibitor SKF 91488.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20021101

Title: Characteristics of recombinantly expressed rat and human histamine H3 receptors.

Journal: European journal of pharmacology 20021018

Title: Histamine H3 receptor activation inhibits neurogenic sympathetic vasoconstriction in porcine nasal mucosa.

Journal: European journal of pharmacology 20021011

Title: Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells.

Journal: The Journal of pharmacology and experimental therapeutics 20021001

Title: Behavioral characterization of mice lacking histamine H(3) receptors.

Journal: Molecular pharmacology 20020801

Title: Different role of the histamine H3-receptor in vagal-, betanechol-, pentagastrin-induced gastric acid secretion in anaesthetized rats.

Journal: Scandinavian journal of gastroenterology 20020701

Title: Betahistine dihydrochloride interaction with the histaminergic system in the cat: neurochemical and molecular mechanisms.

Journal: European journal of pharmacology 20020620

Title: Effects of N-alpha-methyl-histamine on human H(2) receptors expressed in CHO cells.

Journal: Gut 20020601

Title: Histamine H(2) -like receptors in chick cerebral cortex: effects on cyclic AMP synthesis and characterization by [(3) H]tiotidine binding.

Journal: Journal of neurochemistry 20020601

Title: Modulation of the discriminative stimulus effects of cocaine and methamphetamine by the histaminergic system.

Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20020601

Title: Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model.

Journal: Pharmacology, biochemistry, and behavior 20020601

Title: Rodent antinociception following acute treatment with different histamine receptor agonists and antagonists.

Journal: Pharmacology, biochemistry, and behavior 20020601

Title: Experimental anxiety induced by histaminergics in mast cell-deficient and congenitally normal mice.

Journal: Pharmacology, biochemistry, and behavior 20020501

Title: Role of histamine H3 receptors in control of mouse intestinal motility in vivo and in vitro: comparison with alpha2-adrenoceptors.

Journal: Digestive diseases and sciences 20020501

Title: Endogenous histamine in the medial septum-diagonal band complex increases the release of acetylcholine from the hippocampus: a dual-probe microdialysis study in the freely moving rat.

Journal: The European journal of neuroscience 20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Putative effect of Helicobacter pylori and gastritis on gastric acid secretion in cat.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20020401

Title: Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats.

Journal: Acta pharmacologica Sinica 20020401

Title: Contractile response of horse deep dorsal penile vein to histamine.

Journal: International journal of impotence research 20020401

Title: Evidence for activation of histamine H3 autoreceptors during handling stress in the prefrontal cortex of the rat.

Journal: Synapse (New York, N.Y.) 20020315

Title: Histamine excites GABAergic cells in the rat substantia nigra and ventral tegmental area in vitro.

Journal: Neuroscience letters 20020308

Title: Hypothalamic histamine neurons activate lipolysis in rat adipose tissue.

Journal: Experimental biology and medicine (Maywood, N.J.) 20020301

Title: Histamine regulation of interleukin-18-initiating cytokine cascade is associated with down-regulation of intercellular adhesion molecule-1 expression in human peripheral blood mononuclear cells.

Journal: The Journal of pharmacology and experimental therapeutics 20020101

Title: Presynaptic H3 autoreceptors modulate histamine synthesis through cAMP pathway.

Journal: Molecular pharmacology 20020101

Title: Mouse light/dark box test reveals anxiogenic-like effects by activation of histamine H1 receptors.

Journal: Pharmacology, biochemistry, and behavior 20020101

Title: Histamine H3-receptor-mediated [35S]GTP gamma[S] binding: evidence for constitutive activity of the recombinant and native rat and human H3 receptors.

Journal: British journal of pharmacology 20020101

Title: Histamine H3-receptor blockade in the rat nucleus basalis magnocellularis improves place recognition memory.

Journal: Psychopharmacology 20020101

Title: Characterisation of the calcium responses to histamine in capsaicin-sensitive and capsaicin-insensitive sensory neurones.

Journal: Neuroscience 20020101

Title: Muscarinic, adenosine A(2) and histamine H(3) receptor modulation of haloperidol-induced c-fos expression in the striatum and nucleus accumbens.

Journal: Neuroscience 20020101

Title: Influence of SKF 91488, histamine N-methyltransferase inhibitor, on the central cardiovascular regulation during controlled, stepwise hemorrhagic hypotension in rats.

Journal: Polish journal of pharmacology 20020101

Title: Identification of a histamine H4 receptor on human eosinophils--role in eosinophil chemotaxis.

Journal: Journal of receptor and signal transduction research 20020101

Title: Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.

Journal: The Journal of pharmacology and experimental therapeutics 20011201

Title: Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors.

Journal: British journal of pharmacology 20011201

Title: Histamine H3 receptor activation inhibits glutamate release from rat striatal synaptosomes.

Journal: Neuropharmacology 20011201

Title: Dynamics of histamine H(3) receptor antagonists on brain histamine metabolism: do all histamine H(3) receptor antagonists act at a single site?

Journal: European journal of pharmacology 20011116

Title: Effect of L-carnosine on the hyperglycemia caused by intracranial injection of 2-deoxy-D-glucose in rats.

Journal: Neuroscience letters 20011102

Title: Histamine H1 receptors mediate the anorectic action of the pancreatic hormone amylin.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20011101

Title: Histamine H3 receptor-mediated impairment of contextual fear conditioning and in-vivo inhibition of cholinergic transmission in the rat basolateral amygdala.

Journal: The European journal of neuroscience 20011101

Title: Histamine H1 receptor-mediated inhibition of potassium-evoked release of 5-hydroxytryptamine from mouse forebrains.

Journal: Behavioural brain research 20011015

Title: Histamine H(3)-receptor antagonism improves memory retention and reverses the cognitive deficit induced by scopolamine in a two-trial place recognition task.

Journal: Behavioural brain research 20011015

Title: Involvement of central histamine in amygdaloid kindled seizures in rats.

Journal: Behavioural brain research 20011015

Title: Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.

Journal: The Journal of pharmacology and experimental therapeutics 20011001

Title: Inhibitory effect of histamine on axonal transport in cultured mouse dorsal root ganglion neurons.

Journal: Neuroscience research 20011001

Title: Regulation of IL-13 production by histamine in cloned murine T helper type 2 cells.

Journal: International immunopharmacology 20011001

Title: Regional differences in functional receptor distribution and calcium mobilization in the intact human lens.

Journal: Investigative ophthalmology & visual science 20010901

Title: Histaminergic modulation of GABAergic transmission in rat ventromedial hypothalamic neurones.

Journal: The Journal of physiology 20010801

Title: Effects of histamine H3-receptor ligands on brain monoamine oxidase in various mammalian species.

Journal: Brain research 20010706

Title: Disturbance of the prejunctional modulation of cholinergic neurotransmission during chronic granulomatous inflammation of the mouse ileum.

Journal: British journal of pharmacology 20010701

Title: Novel histaprodifen analogues as potent histamine H1-receptor agonists in the pithed and in the anaesthetized rat.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010701

Title: [Identification and characterization of histamine H4 receptor].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010701

Title: The H3 receptor is involved in cholecystokinin inhibition of food intake in rats.

Journal: Life sciences 20010615

Title: Influence of imidazole replacement in different structural classes of histamine H(3)-receptor antagonists.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010601

Title: Development of a pharmacophore model for histamine H3 receptor antagonists, using the newly developed molecular modeling program SLATE.

Journal: Journal of medicinal chemistry 20010524

Title: Activation of histamine H3 receptors inhibits renal noradrenergic neurotransmission in anesthetized dogs.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20010501

Title: Histamine H(3) receptor-mediated inhibition of depolarization-induced, dopamine D(1) receptor-dependent release of [(3)H]-gamma-aminobutryic acid from rat striatal slices.

Journal: British journal of pharmacology 20010501

Title: [Role of central histamine in amygdaloid kindled seizures].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010501

Title: Genomic organization and characterization of splice variants of the human histamine H3 receptor.

Journal: The Biochemical journal 20010415

Title: Different antagonist binding properties of human and rat histamine H3 receptors.

Journal: Bioorganic & medicinal chemistry letters 20010409

Title: Cognitive enhancing properties of thioperamide infused into the nucleus basalis magnocellularis of the rat.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010401

Title: Histamine and selective H3-receptor ligands: a possible role in the mechanism and management of epilepsy.

Journal: Pharmacology, biochemistry, and behavior 20010401

Title: Role of central histaminergic system in lorazepam withdrawal syndrome in rats.

Journal: Pharmacology, biochemistry, and behavior 20010401

Title: Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.

Journal: Molecular pharmacology 20010301

Title: Cloning, expression, and pharmacological characterization of a novel human histamine receptor.

Journal: Molecular pharmacology 20010301

Title: Cloning and characterization of a novel human histamine receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20010301

Title: Histamine H1 and H2 receptor antagonists accelerate skin barrier repair and prevent epidermal hyperplasia induced by barrier disruption in a dry environment.

Journal: The Journal of investigative dermatology 20010201

Title: H3 receptor-mediated inhibition of intestinal acetylcholine release: pharmacological characterization of signal transduction pathways.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20010201

Title: The rat H3 receptor: gene organization and multiple isoforms.

Journal: Biochemical and biophysical research communications 20010112

Title: Histamine H(3) receptors depress synaptic transmission in the corticostriatal pathway.

Journal: Neuropharmacology 20010101

Title: Cortical acetylcholine release elicited by stimulation of histamine H1 receptors in the nucleus basalis magnocellularis: a dual-probe microdialysis study in the freely moving rat.

Journal: The European journal of neuroscience 20010101

Title: Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.

Journal: British journal of pharmacology 20001201

Title: Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes.

Journal: The Journal of biological chemistry 20001124

Title: Identification of a histamine H(3)-like receptor in the zebrafish (Danio rerio) brain.

Journal: Journal of neurochemistry 20000801

Title: Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles.

Journal: The Journal of pharmacology and experimental therapeutics 20000601

Title: Effects of histamine H3 receptor agonists and antagonists on cognitive performance and scopolamine-induced amnesia.

Journal: Behavioural brain research 19991001

Title: Therapeutic doses of theophylline exert proconvulsant effects in developing mice.

Journal: Brain & development 19970901

Title: Inhibitory H3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 19970201

Title: Effect of adenosine and histamine receptor stimulation on canine histamine release to pentagastrin.

Journal: Digestion 19970101

Title: Thioperamide, the selective histamine H3 receptor antagonist, attenuates stimulant-induced locomotor activity in the mouse.

Journal: European journal of pharmacology 19940701

Title: Modulation of the intracellular and H3-histamine receptors and chemically-induced seizures in mice.

Journal: Agents and actions 19940601

Title: Identification of two H3-histamine receptor subtypes.

Journal: Molecular pharmacology 19901101

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Tags:106243-16-7 Molecular Formula|106243-16-7 MDL|106243-16-7 SMILES|106243-16-7 Thioperamide
Catalog No.: AA0035M7
106243-16-7,MFCD00083209
106243-16-7 | Thioperamide
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Purity: ≥99%(HPLC)
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Technical Information
Catalog Number: AA0035M7
Chemical Name: Thioperamide
CAS Number: 106243-16-7
Molecular Formula: C15H24N4S
Molecular Weight: 292.4429
MDL Number: MFCD00083209
SMILES: S=C(N1CCC(CC1)c1cnc[nH]1)NC1CCCCC1
Properties
Complexity: 322  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 20  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 2.4  
Downstream Synthesis Route
106243-23-6    1122-82-3    106243-16-7 

[1]JournalofMedicinalChemistry,1995,vol.38,p.3342-3350

Literature fold

Title: Involvement of the histamine H4 receptor in clozapine-induced hematopoietic toxicity: Vulnerability under granulocytic differentiation of HL-60 cells.

Journal: Toxicology and applied pharmacology20160901

Title: Histamine at low concentrations aggravates rat liver BRL-3A cell injury induced by hypoxia/reoxygenation through histamine H2 receptor in vitro.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20130201

Title: Proxyfan acts as a neutral antagonist of histamine H3 receptors in the feeding-related hypothalamic ventromedial nucleus.

Journal: British journal of pharmacology20121101

Title: Histamine H4 receptor antagonists as potent modulators of mammalian vestibular primary neuron excitability.

Journal: British journal of pharmacology20121001

Title: Ophthalmic antihistamines and H1-H4 receptors.

Journal: Current opinion in allergy and clinical immunology20121001

Title: Role of L-carnosine in the control of blood glucose, blood pressure, thermogenesis, and lipolysis by autonomic nerves in rats: involvement of the circadian clock and histamine.

Journal: Amino acids20120701

Title: A bioinformatics search for selective histamine h4 receptor antagonists through structure-based virtual screening strategies.

Journal: Chemical biology & drug design20120501

Title: Effects of neonatal methamphetamine and thioperamide exposure on spatial memory retention and circadian activity later in life.

Journal: Behavioural brain research20120421

Title: Histamine reverses a memory deficit induced in rats by early postnatal maternal deprivation.

Journal: Neurobiology of learning and memory20120101

Title: Ligand based design of novel histamine H₄ receptor antagonists; fragment optimization and analysis of binding kinetics.

Journal: Bioorganic & medicinal chemistry letters20120101

Title: In vivo receptor occupancy assay of histamine H₃ receptor antagonist in rats using non-radiolabeled tracer.

Journal: Journal of pharmacological and toxicological methods20120101

Title: Anti-stress effects of carnosine on restraint-evoked immunocompromise in mice through spleen lymphocyte number maintenance.

Journal: PloS one20120101

Title: Unusual effects of nicotine as a psychostimulant on ambulatory activity in mice.

Journal: ISRN pharmacology20120101

Title: Histamine is a modulator of metamorphic competence in Strongylocentrotus purpuratus (Echinodermata: Echinoidea).

Journal: BMC developmental biology20120101

Title: Desipramine inhibits histamine H1 receptor-induced Ca2+ signaling in rat hypothalamic cells.

Journal: PloS one20120101

Title: Histamine neurons in the tuberomamillary nucleus: a whole center or distinct subpopulations?

Journal: Frontiers in systems neuroscience20120101

Title: Histamine h3 receptor: a novel therapeutic target in alcohol dependence?

Journal: Frontiers in systems neuroscience20120101

Title: Identification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptor.

Journal: PloS one20120101

Title: The mediation of the central histaminergic system in the pressor effect of intracerebroventricularly injected melittin, a phospholipase A2 activator, in normotensive rats.

Journal: Prostaglandins, leukotrienes, and essential fatty acids20120101

Title: Searching for the Multi-Target-Directed Ligands against Alzheimer's disease: discovery of quinoxaline-based hybrid compounds with AChE, H₃R and BACE 1 inhibitory activities.

Journal: Bioorganic & medicinal chemistry20111201

Title: The role of cortical and hypothalamic histamine-3 receptors in the modulation of central histamine neurotransmission: an in vivo electrophysiology and microdialysis study.

Journal: The European journal of neuroscience20111201

Title: The hydrophobic amino acids in putative helix 8 in carboxy-terminus of histamine H(3) receptor are involved in receptor-G-protein coupling.

Journal: Cellular signalling20111101

Title: Differential modulation of excitatory and inhibitory striatal synaptic transmission by histamine.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20111026

Title: Differential effects of histamine H(3) receptor inverse agonist thioperamide, given alone or in combination with the N-methyl-d-aspartate receptor antagonist dizocilpine, on reconsolidation and consolidation of a contextual fear memory in mice.

Journal: Neuroscience20111013

Title: Histamine facilitates consolidation of fear extinction.

Journal: The international journal of neuropsychopharmacology20111001

Title: In vivo electrochemical evidence for simultaneous 5-HT and histamine release in the rat substantia nigra pars reticulata following medial forebrain bundle stimulation.

Journal: Journal of neurochemistry20110901

Title: Role of the second and third extracellular loops of the histamine H(4) receptor in receptor activation.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20110901

Title: Ontogenetic serotoninergic lesioning alters histaminergic activity in rats in adulthood.

Journal: Neurotoxicity research20110801

Title: Thioperamide, an H₃ receptor antagonist prevents [³H]glucose uptake in brain of adult rats lesioned as neonates with 5,7-dihydroxytryptamine.

Journal: Neurotoxicity research20110701

Title: Involvement of histaminergic receptor mechanisms in the stimulation of NT-3 synthesis in astrocytes.

Journal: Neuropharmacology20110601

Title: Prepulse inhibition of the startle reflex and response to antipsychotic treatments in two outbred mouse strains in comparison to the inbred DBA/2 mouse.

Journal: Psychopharmacology20110601

Title: Memory facilitating effects of agomelatine in the novel object recognition memory paradigm in the rat.

Journal: Pharmacology, biochemistry, and behavior20110601

Title: Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters.

Journal: Physiology & behavior20110601

Title: Regulation of ERK2 phosphorylation by histamine in splenocytes.

Journal: Immunopharmacology and immunotoxicology20110601

Title: The histamine H3 receptor: from discovery to clinical trials with pitolisant.

Journal: British journal of pharmacology20110601

Title: Effects of histamine H3 receptors on chemical hyperalgesia in diabetic rats.

Journal: Neuropharmacology20110501

Title: N-Alkenyl and cycloalkyl carbamates as dual acting histamine H3 and H4 receptor ligands.

Journal: Bioorganic & medicinal chemistry20110501

Title: Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits β-arrestin without activating G proteins.

Journal: Molecular pharmacology20110401

Title: Newer molecules in the treatment of schizophrenia: A clinical update.

Journal: Indian journal of pharmacology20110401

Title: Triazole ligands reveal distinct molecular features that induce histamine H4 receptor affinity and subtly govern H4/H3 subtype selectivity.

Journal: Journal of medicinal chemistry20110324

Title: Antidiabetic properties of the histamine H3 receptor protean agonist proxyfan.

Journal: Endocrinology20110301

Title: Skin application of urea-containing cream affected cutaneous arterial sympathetic nerve activity, blood flow, and water evaporation.

Journal: Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)20110201

Title: Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoids.

Journal: Peptides20110201

Title: [Roles of histamine in the exacerbated allergic dermatitis].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20110201

Title: Histamine H3 receptor as a drug discovery target.

Journal: Journal of medicinal chemistry20110113

Title: H3 receptors and pain modulation: peripheral, spinal, and brain interactions.

Journal: The Journal of pharmacology and experimental therapeutics20110101

Title: Effects of antihistamines on innate immune responses to severe bacterial infection in mice.

Journal: International archives of allergy and immunology20110101

Title: Histaminergic mechanisms for modulation of memory systems.

Journal: Neural plasticity20110101

Title: Inverse agonism and its therapeutic significance.

Journal: Indian journal of pharmacology20110101

Title: Thioperamide induces CD4 CD25 Foxp3 regulatory T lymphocytes in the lung mucosa of allergic mice through its action on dendritic cells.

Journal: Journal of asthma and allergy20110101

Title: Kv4.2 mediates histamine modulation of preoptic neuron activity and body temperature.

Journal: PloS one20110101

Title: Biological Significance of GPCR Heteromerization in the Neuro-Endocrine System.

Journal: Frontiers in endocrinology20110101

Title: Histamine 3 receptor activation mediates inhibition of acid secretion during Helicobacter-induced gastritis.

Journal: World journal of gastrointestinal pathophysiology20101215

Title: Microinjection of histamine into the dentate gyrus produces antinociception in the formalin test in rats.

Journal: Pharmacology, biochemistry, and behavior20101201

Title: Comparison of the pharmacological properties of human and rat histamine H(3)-receptors.

Journal: Biochemical pharmacology20101101

Title: Structural basis of drug binding to CYP46A1, an enzyme that controls cholesterol turnover in the brain.

Journal: The Journal of biological chemistry20101008

Title: Validation and pharmacological characterisation of MK-801-induced locomotor hyperactivity in BALB/C mice as an assay for detection of novel antipsychotics.

Journal: Psychopharmacology20101001

Title: Histamine H(3) receptor modulates nociception in a rat model of cholestasis.

Journal: Pharmacology, biochemistry, and behavior20100901

Title: Environmental stressors and neurobiological features of marine teleosts: histamine receptors as targets.

Journal: Critical reviews in toxicology20100801

Title: Effect of anserine ingestion on hyperglycemia and the autonomic nerves in rats and humans.

Journal: Nutritional neuroscience20100801

Title: Effect of combined treatment of thioperamide with some antiepileptic drugs on methionine-sulfoximine induced convulsions in mice.

Journal: Indian journal of experimental biology20100801

Title: Histamine H3 receptor activation potentiates peripheral opioid-mediated antinociception: substance P role in peripheral inflammation in mice.

Journal: European journal of pharmacology20100725

Title: Effect of anserine ingestion on the hyperglycemia and autonomic nerves in rats and humans.

Journal: Nutritional neuroscience20100601

Title: Effects of sympathetic histamine on vasomotor responses of blood vessels in rabbit ear to electrical stimulation.

Journal: Neuroscience bulletin20100601

Title: Investigation of the bioactive conformation of histamine H3 receptor antagonists by the cyclopropylic strain-based conformational restriction strategy.

Journal: Journal of medicinal chemistry20100513

Title: Molecular determinants of ligand binding to H4R species variants.

Journal: Molecular pharmacology20100501

Title: Impact of the DRY motif and the missing 'ionic lock' on constitutive activity and G-protein coupling of the human histamine H4 receptor.

Journal: The Journal of pharmacology and experimental therapeutics20100501

Title: Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists.

Journal: Bioorganic & medicinal chemistry letters20100415

Title: Synthesis and QSAR of quinazoline sulfonamides as highly potent human histamine H4 receptor inverse agonists.

Journal: Journal of medicinal chemistry20100325

Title: Modulation of histamine H(3) receptor function by monovalent ions.

Journal: Neuroscience letters20100319

Title: Neuropharmacology of vestibular system disorders.

Journal: Current neuropharmacology20100301

Title: Modeling G protein-coupled receptors for structure-based drug discovery using low-frequency normal modes for refinement of homology models: application to H3 antagonists.

Journal: Proteins20100201

Title: Synthesis and structural and pharmacological properties of cyclopropane-based conformationally restricted analogs of 4-methylhistamine as histamine H3/H4 receptor ligands.

Journal: Bioorganic & medicinal chemistry20100201

Title: Involvement of the histaminergic system in cytidine 5'-diphosphocholine-induced reversal of critical haemorrhagic hypotension in rats.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society20100201

Title: Effects of anserine on the renal sympathetic nerve activity and blood pressure in urethane-anesthetized rats.

Journal: Physiological research20100101

Title: Oral L-histidine exerts antihypertensive effects via central histamine H3 receptors and decreases nitric oxide content in the rostral ventrolateral medulla in spontaneously hypertensive rats.

Journal: Clinical and experimental pharmacology & physiology20100101

Title: Contribution of mast cells to the oedema induced by Bothrops moojeni snake venom and a pharmacological assessment of the inflammatory mediators involved.

Journal: Toxicon : official journal of the International Society on Toxinology20100101

Title: Pretreatment with l-histidine produces a shift from methamphetamine-induced stereotypical biting to persistent locomotion in mice.

Journal: Pharmacology, biochemistry, and behavior20100101

Title: R-(-)-alpha-methylhistamine, a histamine H3 receptor agonist, induces endothelium-dependent vasodilation in rat mesenteric resistance arteries.

Journal: Biological & pharmaceutical bulletin20100101

Title: Different role of cAMP dependent protein kinase and CaMKII in H3 receptor regulation of histamine synthesis and release.

Journal: Neuroscience20091215

Title: The effects of thioperamide on extracellular levels of glutamate and GABA in the rat prefrontal cortex.

Journal: Psychopharmacology20091201

Title: Histamine H3 and H4 receptor affinity of branched 3-(1H-imidazol-4-yl)propyl N-alkylcarbamates.

Journal: Bioorganic & medicinal chemistry letters20091201

Title: Heterocyclic replacement of the central phenyl core of diamine-based histamine H3 receptor antagonists.

Journal: European journal of medicinal chemistry20091101

Title: Interactions of histamine H1-receptor agonists and antagonists with the human histamine H4-receptor.

Journal: Molecular pharmacology20091101

Title: Synthesis and structure-activity relationships of cyanoguanidine-type and structurally related histamine H4 receptor agonists.

Journal: Journal of medicinal chemistry20091022

Title: 2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization.

Journal: Bioorganic & medicinal chemistry20091015

Title: Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines.

Journal: European journal of medicinal chemistry20091001

Title: Effects of the H(3) antagonist, thioperamide, on behavioral alterations induced by systemic MK-801 administration in rats.

Journal: Psychopharmacology20090901

Title: Enhanced morphine-induced antinociception in histamine H3 receptor gene knockout mice.

Journal: Neuropharmacology20090901

Title: Anxiolytic-like profiles of histamine H3 receptor agonists in animal models of anxiety: a comparative study with antidepressants and benzodiazepine anxiolytic.

Journal: Psychopharmacology20090801

Title: Development of a selective and potent radioactive ligand for histamine H(3) receptors: A compound potentially useful for receptor occupancy studies.

Journal: Bioorganic & medicinal chemistry letters20090801

Title: JNJ-10181457, a selective non-imidazole histamine H(3) receptor antagonist, normalizes acetylcholine neurotransmission and has efficacy in translational rat models of cognition.

Journal: Neuropharmacology20090601

Title: Clobenpropit analogs as dual activity ligands for the histamine H3 and H4 receptors: synthesis, pharmacological evaluation, and cross-target QSAR studies.

Journal: Bioorganic & medicinal chemistry20090601

Title: Heterogeneity of histaminergic neurons in the tuberomammillary nucleus of the rat.

Journal: The European journal of neuroscience20090601

Title: N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent.

Journal: Journal of medicinal chemistry20090423

Title: Non-imidazole histamine H3 ligands, part IV: SAR of 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives.

Journal: European journal of medicinal chemistry20090401

Title: Characterization of histamine-induced relaxation in pre-contracted rat aorta.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20090401

Title: Histaminergic activity in a rodent model of Parkinson's disease.

Journal: Neurotoxicity research20090401

Title: Effects of the H3 receptor inverse agonist thioperamide on cocaine-induced locomotion in mice: role of the histaminergic system and potential pharmacokinetic interactions.

Journal: Psychopharmacology20090301

Title: The role of histamine 3 receptors in the control of food intake in a seasonal model of obesity: the Siberian hamster.

Journal: Behavioural pharmacology20090301

Title: High constitutive activity and a G-protein-independent high-affinity state of the human histamine H(4)-receptor.

Journal: Biochemistry20090217

Title: Autonomic and cardiovascular effects of central neuromedin U in rats.

Journal: Physiology & behavior20090216

Title: Possible role of the histaminergic system in autonomic and cardiovascular responses to neuropeptide Y.

Journal: Neuropeptides20090201

Title: H3 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing retrieval.

Journal: Psychopharmacology20090101

Title: Modification of the picryl chloride-induced allergic dermatitis model in mouse ear lobes by 12-O-tetradecanoylphorbol 13-acetate, and analysis of the role of histamine in the modified model.

Journal: International archives of allergy and immunology20090101

Title: L-histidine enhances learning in stressed zebrafish.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas20090101

Title: Cytokine responses of intraepithelial lymphocytes are regulated by histamine H(2) receptor.

Journal: Journal of gastroenterology20090101

Title: A novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activation.

Journal: PloS one20090101

Title: Alpha2 adrenoceptors modulate histamine release from sympathetic nerves in the guinea pig vas deferens.

Journal: Neuropharmacology20090101

Title: H4 histamine receptors mediate cell cycle arrest in growth factor-induced murine and human hematopoietic progenitor cells.

Journal: PloS one20090101

Title: Modulatory effects of histamine on cat carotid body chemoreception.

Journal: Respiratory physiology & neurobiology20081231

Title: Discovery of quinazolines as histamine H4 receptor inverse agonists using a scaffold hopping approach.

Journal: Journal of medicinal chemistry20081225

Title: Role of histamine in short- and long-term effects of methamphetamine on the developing mouse brain.

Journal: Journal of neurochemistry20081101

Title: Biphasic effects of orexin-A on autonomic nerve activity and lipolysis.

Journal: Neuroscience letters20081024

Title: Effect of thioperamide on oxidative stress markers in middle cerebral artery occlusion model of focal cerebral ischemia in rats.

Journal: Human & experimental toxicology20081001

Title: The alkaloid conessine and analogues as potent histamine H3 receptor antagonists.

Journal: Journal of medicinal chemistry20080911

Title: Electrophysiology-based analysis of human histamine H(4) receptor pharmacology using GIRK channel coupling in Xenopus oocytes.

Journal: European journal of pharmacology20080904

Title: Localization and function of histamine H3 receptor in the nasal mucosa.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20080901

Title: Alleviation of ischemia-induced brain edema by activation of the central histaminergic system in rats.

Journal: Journal of pharmacological sciences20080901

Title: Regulation of sympathetic nerve activity by L-carnosine in mammalian white adipose tissue.

Journal: Neuroscience letters20080815

Title: Discovery of novel human histamine H4 receptor ligands by large-scale structure-based virtual screening.

Journal: Journal of medicinal chemistry20080612

Title: Correlation between ex vivo receptor occupancy and wake-promoting activity of selective H3 receptor antagonists.

Journal: The Journal of pharmacology and experimental therapeutics20080601

Title: Blocking histamine H(1) improves learning and mnemonic dysfunction in mice with social isolation plus repeated methamphetamine injection.

Journal: Journal of pharmacological sciences20080601

Title: Zebrafish: An in vivo model for the study of neurological diseases.

Journal: Neuropsychiatric disease and treatment20080601

Title: Narcolepsy: current treatment options and future approaches.

Journal: Neuropsychiatric disease and treatment20080601

Title: Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function.

Journal: Neuropharmacology20080516

Title: Fragment based design of new H4 receptor-ligands with anti-inflammatory properties in vivo.

Journal: Journal of medicinal chemistry20080424

Title: Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses.

Journal: The Journal of biological chemistry20080418

Title: Role of histamine in brain protection in surgical brain injury in mice.

Journal: Brain research20080418

Title: Effects of oolong tea on renal sympathetic nerve activity and spontaneous hypertension in rats.

Journal: Metabolism: clinical and experimental20080401

Title: Ontogenetic noradrenergic lesion alters histaminergic activity in adult rats.

Journal: Neurotoxicity research20080401

Title: Specific cerebral heat shock proteins and histamine receptor cross-talking mechanisms promote distinct lead-dependent neurotoxic responses in teleosts.

Journal: Toxicology and applied pharmacology20080301

Title: Comparative effects of olanzapine and ziprasidone on hypophagia induced by enhanced histamine neurotransmission in the rat.

Journal: Behavioural pharmacology20080301

Title: Carnosine protects against Abeta42-induced neurotoxicity in differentiated rat PC12 cells.

Journal: Cellular and molecular neurobiology20080201

Title: Effects of central histamine receptors blockade on GABA(A) agonist-induced food intake in broiler cockerels.

Journal: Pakistan journal of biological sciences : PJBS20080201

Title: Antigen inhalation induces mast cells and eosinophils infiltration in the guinea pig esophageal epithelium involving histamine-mediated pathway.

Journal: Life sciences20080130

Title: Distinctive role of central histamine H3 receptor in various orexigenic pathways.

Journal: European journal of pharmacology20080128

Title: CSF histamine levels in rats reflect the central histamine neurotransmission.

Journal: Neuroscience letters20080117

Title: Modulation of hippocampal theta oscillation by histamine H3 receptors.

Journal: The Journal of pharmacology and experimental therapeutics20080101

Title: Mast cell-derived histamine mediates cystitis pain.

Journal: PloS one20080101

Title: Histamine H(3) receptor ligands modulate L-dopa-evoked behavioral responses and L-dopa derived extracellular dopamine in dopamine-denervated rat striatum.

Journal: Neurotoxicity research20080101

Title: Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cells.

Journal: BMC pharmacology20080101

Title: Histamine-induced itch and its relationship with pain.

Journal: Molecular pain20080101

Title: The possible involvement of hyperpolarizing mechanisms in histamine-induced relaxation of the rat portal vein.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi20080101

Title: Histamine in Macaca mulatto monkey cardiac sympathetic nerve system: a morphological and functional assessment.

Journal: Autonomic neuroscience : basic & clinical20071230

Title: Functional expression of H4 histamine receptor in human natural killer cells, monocytes, and dendritic cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20071201

Title: The role of carcinine in signaling at the Drosophila photoreceptor synapse.

Journal: PLoS genetics20071201

Title: Activation of peripheral and spinal histamine H3 receptors inhibits formalin-induced inflammation and nociception, respectively.

Journal: Pharmacology, biochemistry, and behavior20071101

Title: Reduced histamine levels and H3 receptor antagonist-induced histamine release in the amygdala of Apoe-/- mice.

Journal: Journal of neurochemistry20071001

Title: The Akt/GSK-3beta axis as a new signaling pathway of the histamine H(3) receptor.

Journal: Journal of neurochemistry20071001

Title: Histamine improves antigen uptake and cross-presentation by dendritic cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20070915

Title: Interaction of nicotinic and histamine H(3) systems in the radial-arm maze repeated acquisition task.

Journal: European journal of pharmacology20070813

Title: Betahistine in the treatment of Ménière's disease.

Journal: Neuropsychiatric disease and treatment20070801

Title: Histaminergic ligands improve vestibular compensation in the cat: behavioural, neurochemical and molecular evidence.

Journal: European journal of pharmacology20070730

Title: Blockade of brain histamine metabolism alters methamphetamine-induced expression pattern of stereotypy in mice via histamine H1 receptors.

Journal: Neuroscience20070713

Title: Histamine H4 receptor agonists have more activities than H4 agonism in antigen-specific human T-cell responses.

Journal: Immunology20070601

Title: Interaction of calcitonin gene-related peptide, nitric oxide and histamine release in neurogenic blood flow and afferent activation in the rat cranial dura mater.

Journal: Cephalalgia : an international journal of headache20070601

Title: H3 histamine receptor agonist inhibits biliary growth of BDL rats by downregulation of the cAMP-dependent PKA/ERK1/2/ELK-1 pathway.

Journal: Laboratory investigation; a journal of technical methods and pathology20070501

Title: Histaminergic H1 receptors mediate L-histidine-induced anxiety in elevated plus-maze test in mice.

Journal: Behavioural pharmacology20070501

Title: Identification of zebrafish histamine H1, H2 and H3 receptors and effects of histaminergic ligands on behavior.

Journal: Biochemical pharmacology20070415

Title: The brain H3-receptor as a novel therapeutic target for vigilance and sleep-wake disorders.

Journal: Biochemical pharmacology20070415

Title: Auditory stimulation affects renal sympathetic nerve activity and blood pressure in rats.

Journal: Neuroscience letters20070412

Title: Thioperamide reduces intracellular calcium in mouse brain synaptosomes.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology20070401

Title: Influence of the H3/H4 receptor antagonist, thioperamide on regional haemodynamics in rats with trinitrobenzene sulfonic acid-induced colitis.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20070401

Title: Thioperamide delays vestibular compensation in goldfish.

Journal: Neuroscience letters20070326

Title: Sex- and histamine-dependent long-term cognitive effects of methamphetamine exposure.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20070301

Title: Carnosine protects against NMDA-induced neurotoxicity in differentiated rat PC12 cells through carnosine-histidine-histamine pathway and H(1)/H(3) receptors.

Journal: Biochemical pharmacology20070301

Title: Histamine affects STAT6 phosphorylation via its effects on IL-4 secretion: role of H1 receptors in the regulation of IL-4 production.

Journal: International immunopharmacology20070301

Title: Suppression of inflammatory cell recruitment by histamine receptor stimulation in ischemic rat brains.

Journal: European journal of pharmacology20070227

Title: Involvement of the histaminergic system in renal sympathetic and cardiovascular responses to leptin and ghrelin.

Journal: Neuroscience letters20070208

Title: In vitro pharmacology at human histamine H3 receptors and brain access of non-imidazole alkylpiperidine derivatives.

Journal: Pharmacological research20070201

Title: Modification of formalin-induced nociception by different histamine receptor agonists and antagonists.

Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology20070115

Title: Role of apolipoprotein E in anxiety.

Journal: Neural plasticity20070101

Title: Role of histamine H3 and H4 receptors in mechanical hyperalgesia following peripheral nerve injury.

Journal: Neuroimmunomodulation20070101

Title: Histamine H3 receptor agonist- and antagonist-evoked vacuous chewing movements in 6-OHDA-lesioned rats occurs in an absence of change in microdialysate dopamine levels.

Journal: European journal of pharmacology20061215

Title: Feeding differences in pubertal and aged golden hamsters (Mesocricetus auratus) are related to specific cerebral expression pattern of histamine subtype 3 receptor.

Journal: Behavioral neuroscience20061201

Title: Expression of histamine receptors and effect of histamine in the rat carotid body chemoafferent pathway.

Journal: The European journal of neuroscience20061201

Title: Mechanism of imipramine-induced seizures in amygdala-kindled rats.

Journal: Epilepsy research20061101

Title: Renoprotective effects of l-carnosine on ischemia/reperfusion-induced renal injury in rats.

Journal: The Journal of pharmacology and experimental therapeutics20061101

Title: Dose-different effects of orexin-A on the renal sympathetic nerve and blood pressure in urethane-anesthetized rats.

Journal: Experimental biology and medicine (Maywood, N.J.)20061101

Title: A comparison of protective effects between L-histidine and hypothermia against ischemia-induced neuronal damage in gerbil hippocampus.

Journal: European journal of pharmacology20060928

Title: Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure.

Journal: Journal of medicinal chemistry20060907

Title: Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway.

Journal: Neuropharmacology20060901

Title: Suppression of ischemia/reperfusion liver injury by histamine H4 receptor stimulation in rats.

Journal: European journal of pharmacology20060821

Title: Homologous down-regulation of histamine H3 receptors in rat striatal slices.

Journal: Synapse (New York, N.Y.)20060801

Title: Antipsychotic-like profile of thioperamide, a selective H3-receptor antagonist in mice.

Journal: Fundamental & clinical pharmacology20060801

Title: Evidence for histamine as a neurotransmitter in the cardiac sympathetic nervous system.

Journal: American journal of physiology. Heart and circulatory physiology20060701

Title: Histamine enhances inhibitory avoidance memory consolidation through a H2 receptor-dependent mechanism.

Journal: Neurobiology of learning and memory20060701

Title: Impaired drinking response in histamine H3 receptor knockout mice following dehydration or angiotensin-II challenge.

Journal: Pharmacology, biochemistry, and behavior20060701

Title: Increasing synaptic noradrenaline, serotonin and histamine enhances in vivo binding of phosphodiesterase-4 inhibitor (R)-[11C]rolipram in rat brain, lung and heart.

Journal: Life sciences20060620

Title: Changes in the histaminergic system during vestibular compensation in the cat.

Journal: The Journal of physiology20060615

Title: The effect of histamine on field-stimulated contractions of the guinea-pig prostate.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20060601

Title: Histamine-induced enhancement of vasopressin and oxytocin secretion in rat neurohypophyseal tissue cultures.

Journal: Regulatory peptides20060515

Title: Olfactory stimulation with scent of lavender oil affects autonomic neurotransmission and blood pressure in rats.

Journal: Neuroscience letters20060501

Title: Compared pharmacology of human histamine H3 and H4 receptors: structure-activity relationships of histamine derivatives.

Journal: British journal of pharmacology20060401

Title: Effects of the H3-receptor inverse agonist thioperamide on the psychomotor effects induced by acutely and repeatedly given cocaine in C57BL/6J mice.

Journal: Pharmacology, biochemistry, and behavior20060401

Title: Effects of histamine H(3) antagonists and donepezil on learning and mnemonic deficits induced by pentylenetetrazol kindling in weanling mice.

Journal: Neuropharmacology20060301

Title: Role of H1 receptors in histamine-mediated up-regulation of STAT4 phosphorylation.

Journal: International immunopharmacology20060301

Title: Histamine protects against NMDA-induced necrosis in cultured cortical neurons through H receptor/cyclic AMP/protein kinase A and H receptor/GABA release pathways.

Journal: Journal of neurochemistry20060301

Title: Histamine increases sickle erythrocyte adherence to endothelium.

Journal: British journal of haematology20060201

Title: [The effect of central histamine H3 receptor on breathing activity of asthmatic guinea pigs].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology20060201

Title: Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20060125

Title: The hallucinogenic herb Salvia divinorum and its active ingredient salvinorin A inhibit enteric cholinergic transmission in the guinea-pig ileum.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society20060101

Title: Histamine receptors influence blood-spinal cord barrier permeability, edema formation, and spinal cord blood flow following trauma to the rat spinal cord.

Journal: Acta neurochirurgica. Supplement20060101

Title: Aversive memory reactivation engages in the amygdala only some neurotransmitters involved in consolidation.

Journal: Learning & memory (Cold Spring Harbor, N.Y.)20060101

Title: Reduction in brain infarction by augmentation of central histaminergic activity in rats.

Journal: Brain research20051220

Title: Histamine (H3) receptors modulate the excitatory amino acid receptor response of the vestibular afferents.

Journal: Brain research20051207

Title: Effects of intraduodenal injection of Lactobacillus johnsonii La1 on renal sympathetic nerve activity and blood pressure in urethane-anesthetized rats.

Journal: Neuroscience letters20051202

Title: Mechanisms of histamine-induced relaxation in bovine small adrenal cortical arteries.

Journal: American journal of physiology. Endocrinology and metabolism20051201

Title: Sleep disturbances, psychiatric disorders, and psychotropic drugs.

Journal: Dialogues in clinical neuroscience20051201

Title: Some environmental contaminants influence motor and feeding behaviors in the ornate wrasse (Thalassoma pavo) via distinct cerebral histamine receptor subtypes.

Journal: Environmental health perspectives20051101

Title: The histaminergic signaling system exerts a neuroprotective role against neurodegenerative-induced processes in the hamster.

Journal: The Journal of pharmacology and experimental therapeutics20051001

Title: Modulation of spontaneous alternation performance of mice treated with thioperamide and tacrine in a cross maze task.

Journal: Fundamental & clinical pharmacology20051001

Title: Effect of thioperamide on modified forced swimming test-induced oxidative stress in mice.

Journal: Basic & clinical pharmacology & toxicology20051001

Title: Olfactory stimulation with scent of lavender oil affects autonomic nerves, lipolysis and appetite in rats.

Journal: Neuroscience letters20050701

Title: Involvement of histamine H1 and H2 receptors in the regulation of STAT-1 phosphorylation: inverse agonism exhibited by the receptor antagonists.

Journal: International immunopharmacology20050701

Title: Histamine excites noradrenergic neurons in locus coeruleus in rats.

Journal: Neuropharmacology20050701

Title: Histamine-3 receptor antagonists reduce superoxide anion generation and lipid peroxidation in rat brain homogenates.

Journal: The Journal of pharmacy and pharmacology20050601

Title: Generation of cell lines for drug discovery through random activation of gene expression: application to the human histamine H3 receptor.

Journal: Assay and drug development technologies20050601

Title: Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs.

Journal: Brain research20050531

Title: The H3 antagonist thioperamide reveals conditioned preference for a context associated with an inactive small dose of cocaine in C57BL/6J mice.

Journal: Behavioural brain research20050507

Title: Effects of histamine H3 receptor antagonists in two models of spatial learning.

Journal: Behavioural brain research20050430

Title: Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist.

Journal: The Journal of pharmacology and experimental therapeutics20050401

Title: 4-phenoxypiperidines: potent, conformationally restricted, non-imidazole histamine H3 antagonists.

Journal: Journal of medicinal chemistry20050324

Title: Effect of combined histamine H1 and H3 receptor blockade on cutaneous microvascular permeability elicited by compound 48/80.

Journal: Life sciences20050304

Title: Histamine receptors that influence blockage of the normal human nasal airway.

Journal: British journal of pharmacology20050301

Title: Assessment of pharmacology and potential anti-obesity properties of H3 receptor antagonists/inverse agonists.

Journal: Expert opinion on investigational drugs20050301

Title: Dose-dependent effects of L-carnosine on the renal sympathetic nerve and blood pressure in urethane-anesthetized rats.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20050201

Title: A biochemical and pharmacological examination of Rhamphiophis oxyrhynchus (Rufous beaked snake) venom.

Journal: Toxicon : official journal of the International Society on Toxinology20050201

Title: Role of capsaicin-sensitive nerves and histamine H1, H2, and H3 receptors in the gastroprotective effect of histamine against stress ulcers in rats.

Journal: European journal of pharmacology20050131

Title: 4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention.

Journal: Journal of medicinal chemistry20050113

Title: 2-(4-alkylpiperazin-1-yl)quinolines as a new class of imidazole-free histamine H3 receptor antagonists.

Journal: Journal of medicinal chemistry20050113

Title: Histaminergic modulation of excitatory synaptic transmission in the rat basolateral amygdala.

Journal: Neuroscience20050101

Title: Histamine-induced cyclic AMP formation in the chick hypothalamus: interaction with vasoactive intestinal peptide.

Journal: Pharmacological reports : PR20050101

Title: [Participation of cyclic nucleotides and phospholipidis in signal transduction of histamin receptor H3 of the gastric mucosa parietal cells in rats with experimental ulcer].

Journal: Ukrains'kyi biokhimichnyi zhurnal (1999 )20050101

Title: Role of histaminergic neurons in development of epileptic seizures in EL mice.

Journal: Brain research. Molecular brain research20041206

Title: Unusual functional properties of homo- and heteromultimeric histamine-gated chloride channels of Drosophila melanogaster: spontaneous currents and dual gating by GABA and histamine.

Journal: Neuroscience letters20041130

Title: Pharmacological effects of carcinine on histaminergic neurons in the brain.

Journal: British journal of pharmacology20041101

Title: Medicinal chemical and pharmacological aspects of imidazole-containing histamine H3 receptor antagonists.

Journal: Mini reviews in medicinal chemistry20041101

Title: Role of the histamine system in nefopam-induced antinociception in mice.

Journal: European journal of pharmacology20041025

Title: Histamine H3 receptors inhibit serotonin release in substantia nigra pars reticulata.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20041006

Title: Intranigral injection of the H3 agonist immepip and systemic apomorphine elicit ipsilateral turning behaviour in naive rats, but reduce contralateral turning in hemiparkinsonian rats.

Journal: Behavioural brain research20041005

Title: The in vitro and in vivo pharmacological activity of Boiga dendrophila (mangrove catsnake) venom.

Journal: Autonomic & autacoid pharmacology20041001

Title: Histamine H3 antagonist thioperamide dose-dependently enhances memory consolidation and reverses amnesia induced by dizocilpine or scopolamine in a one-trial inhibitory avoidance task in mice.

Journal: Behavioural brain research20040923

Title: Pharmacological and behavioral properties of A-349821, a selective and potent human histamine H3 receptor antagonist.

Journal: Biochemical pharmacology20040901

Title: Cloning and expression of the mouse histamine H3 receptor: evidence for multiple isoforms.

Journal: Journal of neurochemistry20040901

Title: Enhancement of prepulse inhibition of startle in mice by the H3 receptor antagonists thioperamide and ciproxifan.

Journal: Behavioural brain research20040812

Title: Liver-expressed chemokine/CC chemokine ligand 16 attracts eosinophils by interacting with histamine H4 receptor.

Journal: Journal of immunology (Baltimore, Md. : 1950)20040801

Title: Histamine H3 receptor activation inhibits dopamine D1 receptor-induced cAMP accumulation in rat striatal slices.

Journal: Neuroscience letters20040708

Title: Critical role of L-selectin and histamine H4 receptor in zymosan-induced neutrophil recruitment from the bone marrow: comparison with carrageenan.

Journal: The Journal of pharmacology and experimental therapeutics20040701

Title: Meta-substituted aryl(thio)ethers as potent partial agonists (or antagonists) for the histamine H3 receptor lacking a nitrogen atom in the side chain.

Journal: Journal of medicinal chemistry20040603

Title: Central H3R activation by thioperamide does not affect energy balance.

Journal: Pharmacology, biochemistry, and behavior20040601

Title: 1-alkyl-4-acylpiperazines as a new class of imidazole-free histamine H(3) receptor antagonists.

Journal: Journal of medicinal chemistry20040520

Title: 4-(omega-(alkyloxy)alkyl)-1H-imidazole derivatives as histamine H(3) receptor antagonists/agonists.

Journal: Journal of medicinal chemistry20040506

Title: Involvement of histamine H4 and H1 receptors in scratching induced by histamine receptor agonists in Balb C mice.

Journal: British journal of pharmacology20040501

Title: Histamine H4 receptor mediates eosinophil chemotaxis with cell shape change and adhesion molecule upregulation.

Journal: British journal of pharmacology20040501

Title: Intracerebroventricular administration of histamine H3 receptor antagonists decreases seizures in rat models of epilepsia.

Journal: Methods and findings in experimental and clinical pharmacology20040501

Title: Histamine h3 receptor antagonists potentiate methamphetamine self-administration and methamphetamine-induced accumbal dopamine release.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology20040401

Title: Inhibitory effect of iodophenpropit, a selective histamine H3 antagonist, on amygdaloid kindled seizures.

Journal: Brain research bulletin20040315

Title: Pruritus-associated response mediated by cutaneous histamine H3 receptors.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20040301

Title: Thioperamide-elicited increase of histamine release from basolateral amygdala of freely moving rats and its therapeutic implications.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20040301

Title: Role of histamine H3 receptors during ischemia/reperfusion in isolated rat hearts.

Journal: Journal of cardiovascular pharmacology20040301

Title: Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat.

Journal: BMC neuroscience20040101

Title: Critical role of histamine H4 receptor in leukotriene B4 production and mast cell-dependent neutrophil recruitment induced by zymosan in vivo.

Journal: The Journal of pharmacology and experimental therapeutics20031201

Title: Role of histamine receptors in the regulation of edema and circulation postburn.

Journal: Burns : journal of the International Society for Burn Injuries20031201

Title: Histamine induces cytoskeletal changes in human eosinophils via the H(4) receptor.

Journal: British journal of pharmacology20031101

Title: Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves.

Journal: Experimental biology and medicine (Maywood, N.J.)20031101

Title: Generation and characterization of highly constitutive active histamine H3 receptors.

Journal: The Journal of pharmacology and experimental therapeutics20031001

Title: Aminergic control of high-frequency (approximately 200 Hz) network oscillations in the hippocampus of the behaving rat.

Journal: Neuroscience letters20030911

Title: The first potent and selective non-imidazole human histamine H4 receptor antagonists.

Journal: Journal of medicinal chemistry20030911

Title: Central endogenous histamine modulates sympathetic outflow through H3 receptors in the conscious rabbit.

Journal: British journal of pharmacology20030701

Title: Identification of a dual histamine H1/H3 receptor ligand based on the H1 antagonist chlorpheniramine.

Journal: Bioorganic & medicinal chemistry letters20030616

Title: Antinociceptive mechanisms of orally administered decursinol in the mouse.

Journal: Life sciences20030613

Title: Activation of spinal histamine H3 receptors inhibits mechanical nociception.

Journal: European journal of pharmacology20030606

Title: Two novel and selective nonimidazole H3 receptor antagonists A-304121 and A-317920: II. In vivo behavioral and neurophysiological characterization.

Journal: The Journal of pharmacology and experimental therapeutics20030601

Title: Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.

Journal: The Journal of pharmacology and experimental therapeutics20030601

Title: Histamine H4 receptor mediates chemotaxis and calcium mobilization of mast cells.

Journal: The Journal of pharmacology and experimental therapeutics20030601

Title: H3 receptor blockade by thioperamide enhances cognition in rats without inducing locomotor sensitization.

Journal: Psychopharmacology20030601

Title: Cyclopropane-based conformational restriction of histamine. (1S,2S)-2-(2-aminoethyl)-1-(1H-imidazol-4-yl)cyclopropane, a highly selective agonist for the histamine H3 receptor, having a cis-cyclopropane structure.

Journal: Journal of medicinal chemistry20030508

Title: Regulation by prostaglandin E2 and histamine of angiogenesis in inflammatory granulation tissue.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan20030501

Title: Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.

Journal: Journal of medicinal chemistry20030410

Title: Histamine inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production in an intercellular adhesion molecule-1- and B7.1-dependent manner.

Journal: The Journal of pharmacology and experimental therapeutics20030201

Title: Histaminergic modulation of the intact respiratory network of adult mice.

Journal: Pflugers Archiv : European journal of physiology20030201

Title: Histamine-induced chloride secretion is mediated via H2-receptors in the pig proximal colon.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20030201

Title: Neuroimmune interactions in guinea pig stomach and small intestine.

Journal: American journal of physiology. Gastrointestinal and liver physiology20030101

Title: Functional identification of epithelial and smooth muscle histamine-dependent relaxing mechanisms in the bovine trachea, but not in bronchi.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP20030101

Title: Replacement of imidazole by a piperidine moiety differentially affects the potency of histamine H3-receptor antagonists.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20030101

Title: High-frequency oscillation in the hippocampus of the behaving rat and its modulation by the histaminergic system.

Journal: Hippocampus20030101

Title: Contribution of the histaminergic receptor subtypes to histamine-induced cerebellar granular neurotoxicity.

Journal: Polish journal of pharmacology20030101

Title: Targeted disruption of H3 receptors results in changes in brain histamine tone leading to an obese phenotype.

Journal: The Journal of clinical investigation20021215

Title: Novel human histamine H(3) receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters20021118

Title: Coordination of histamine H3 receptor antagonists with human adrenal cytochrome P450 enzymes.

Journal: Pharmacology20021101

Title: Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.

Journal: British journal of pharmacology20021101

Title: Endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats--studies with histamine N-methyltransferase inhibitor SKF 91488.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20021101

Title: Characteristics of recombinantly expressed rat and human histamine H3 receptors.

Journal: European journal of pharmacology20021018

Title: Histamine H3 receptor activation inhibits neurogenic sympathetic vasoconstriction in porcine nasal mucosa.

Journal: European journal of pharmacology20021011

Title: Histamine h(4) and h(2) receptors control histamine-induced interleukin-16 release from human CD8(+) T cells.

Journal: The Journal of pharmacology and experimental therapeutics20021001

Title: Behavioral characterization of mice lacking histamine H(3) receptors.

Journal: Molecular pharmacology20020801

Title: Different role of the histamine H3-receptor in vagal-, betanechol-, pentagastrin-induced gastric acid secretion in anaesthetized rats.

Journal: Scandinavian journal of gastroenterology20020701

Title: Betahistine dihydrochloride interaction with the histaminergic system in the cat: neurochemical and molecular mechanisms.

Journal: European journal of pharmacology20020620

Title: Effects of N-alpha-methyl-histamine on human H(2) receptors expressed in CHO cells.

Journal: Gut20020601

Title: Histamine H(2) -like receptors in chick cerebral cortex: effects on cyclic AMP synthesis and characterization by [(3) H]tiotidine binding.

Journal: Journal of neurochemistry20020601

Title: Modulation of the discriminative stimulus effects of cocaine and methamphetamine by the histaminergic system.

Journal: Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology20020601

Title: Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model.

Journal: Pharmacology, biochemistry, and behavior20020601

Title: Rodent antinociception following acute treatment with different histamine receptor agonists and antagonists.

Journal: Pharmacology, biochemistry, and behavior20020601

Title: Experimental anxiety induced by histaminergics in mast cell-deficient and congenitally normal mice.

Journal: Pharmacology, biochemistry, and behavior20020501

Title: Role of histamine H3 receptors in control of mouse intestinal motility in vivo and in vitro: comparison with alpha2-adrenoceptors.

Journal: Digestive diseases and sciences20020501

Title: Endogenous histamine in the medial septum-diagonal band complex increases the release of acetylcholine from the hippocampus: a dual-probe microdialysis study in the freely moving rat.

Journal: The European journal of neuroscience20020501

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry20020419

Title: Putative effect of Helicobacter pylori and gastritis on gastric acid secretion in cat.

Journal: American journal of physiology. Gastrointestinal and liver physiology20020401

Title: Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats.

Journal: Acta pharmacologica Sinica20020401

Title: Contractile response of horse deep dorsal penile vein to histamine.

Journal: International journal of impotence research20020401

Title: Evidence for activation of histamine H3 autoreceptors during handling stress in the prefrontal cortex of the rat.

Journal: Synapse (New York, N.Y.)20020315

Title: Histamine excites GABAergic cells in the rat substantia nigra and ventral tegmental area in vitro.

Journal: Neuroscience letters20020308

Title: Hypothalamic histamine neurons activate lipolysis in rat adipose tissue.

Journal: Experimental biology and medicine (Maywood, N.J.)20020301

Title: Histamine regulation of interleukin-18-initiating cytokine cascade is associated with down-regulation of intercellular adhesion molecule-1 expression in human peripheral blood mononuclear cells.

Journal: The Journal of pharmacology and experimental therapeutics20020101

Title: Presynaptic H3 autoreceptors modulate histamine synthesis through cAMP pathway.

Journal: Molecular pharmacology20020101

Title: Mouse light/dark box test reveals anxiogenic-like effects by activation of histamine H1 receptors.

Journal: Pharmacology, biochemistry, and behavior20020101

Title: Histamine H3-receptor-mediated [35S]GTP gamma[S] binding: evidence for constitutive activity of the recombinant and native rat and human H3 receptors.

Journal: British journal of pharmacology20020101

Title: Histamine H3-receptor blockade in the rat nucleus basalis magnocellularis improves place recognition memory.

Journal: Psychopharmacology20020101

Title: Characterisation of the calcium responses to histamine in capsaicin-sensitive and capsaicin-insensitive sensory neurones.

Journal: Neuroscience20020101

Title: Muscarinic, adenosine A(2) and histamine H(3) receptor modulation of haloperidol-induced c-fos expression in the striatum and nucleus accumbens.

Journal: Neuroscience20020101

Title: Influence of SKF 91488, histamine N-methyltransferase inhibitor, on the central cardiovascular regulation during controlled, stepwise hemorrhagic hypotension in rats.

Journal: Polish journal of pharmacology20020101

Title: Identification of a histamine H4 receptor on human eosinophils--role in eosinophil chemotaxis.

Journal: Journal of receptor and signal transduction research20020101

Title: Constitutive activity of histamine h(3) receptors stably expressed in SK-N-MC cells: display of agonism and inverse agonism by H(3) antagonists.

Journal: The Journal of pharmacology and experimental therapeutics20011201

Title: Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors.

Journal: British journal of pharmacology20011201

Title: Histamine H3 receptor activation inhibits glutamate release from rat striatal synaptosomes.

Journal: Neuropharmacology20011201

Title: Dynamics of histamine H(3) receptor antagonists on brain histamine metabolism: do all histamine H(3) receptor antagonists act at a single site?

Journal: European journal of pharmacology20011116

Title: Effect of L-carnosine on the hyperglycemia caused by intracranial injection of 2-deoxy-D-glucose in rats.

Journal: Neuroscience letters20011102

Title: Histamine H1 receptors mediate the anorectic action of the pancreatic hormone amylin.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20011101

Title: Histamine H3 receptor-mediated impairment of contextual fear conditioning and in-vivo inhibition of cholinergic transmission in the rat basolateral amygdala.

Journal: The European journal of neuroscience20011101

Title: Histamine H1 receptor-mediated inhibition of potassium-evoked release of 5-hydroxytryptamine from mouse forebrains.

Journal: Behavioural brain research20011015

Title: Histamine H(3)-receptor antagonism improves memory retention and reverses the cognitive deficit induced by scopolamine in a two-trial place recognition task.

Journal: Behavioural brain research20011015

Title: Involvement of central histamine in amygdaloid kindled seizures in rats.

Journal: Behavioural brain research20011015

Title: Comparison of human, mouse, rat, and guinea pig histamine H4 receptors reveals substantial pharmacological species variation.

Journal: The Journal of pharmacology and experimental therapeutics20011001

Title: Inhibitory effect of histamine on axonal transport in cultured mouse dorsal root ganglion neurons.

Journal: Neuroscience research20011001

Title: Regulation of IL-13 production by histamine in cloned murine T helper type 2 cells.

Journal: International immunopharmacology20011001

Title: Regional differences in functional receptor distribution and calcium mobilization in the intact human lens.

Journal: Investigative ophthalmology & visual science20010901

Title: Histaminergic modulation of GABAergic transmission in rat ventromedial hypothalamic neurones.

Journal: The Journal of physiology20010801

Title: Effects of histamine H3-receptor ligands on brain monoamine oxidase in various mammalian species.

Journal: Brain research20010706

Title: Disturbance of the prejunctional modulation of cholinergic neurotransmission during chronic granulomatous inflammation of the mouse ileum.

Journal: British journal of pharmacology20010701

Title: Novel histaprodifen analogues as potent histamine H1-receptor agonists in the pithed and in the anaesthetized rat.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20010701

Title: [Identification and characterization of histamine H4 receptor].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica20010701

Title: The H3 receptor is involved in cholecystokinin inhibition of food intake in rats.

Journal: Life sciences20010615

Title: Influence of imidazole replacement in different structural classes of histamine H(3)-receptor antagonists.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences20010601

Title: Development of a pharmacophore model for histamine H3 receptor antagonists, using the newly developed molecular modeling program SLATE.

Journal: Journal of medicinal chemistry20010524

Title: Activation of histamine H3 receptors inhibits renal noradrenergic neurotransmission in anesthetized dogs.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20010501

Title: Histamine H(3) receptor-mediated inhibition of depolarization-induced, dopamine D(1) receptor-dependent release of [(3)H]-gamma-aminobutryic acid from rat striatal slices.

Journal: British journal of pharmacology20010501

Title: [Role of central histamine in amygdaloid kindled seizures].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica20010501

Title: Genomic organization and characterization of splice variants of the human histamine H3 receptor.

Journal: The Biochemical journal20010415

Title: Different antagonist binding properties of human and rat histamine H3 receptors.

Journal: Bioorganic & medicinal chemistry letters20010409

Title: Cognitive enhancing properties of thioperamide infused into the nucleus basalis magnocellularis of the rat.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.]20010401

Title: Histamine and selective H3-receptor ligands: a possible role in the mechanism and management of epilepsy.

Journal: Pharmacology, biochemistry, and behavior20010401

Title: Role of central histaminergic system in lorazepam withdrawal syndrome in rats.

Journal: Pharmacology, biochemistry, and behavior20010401

Title: Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow.

Journal: Molecular pharmacology20010301

Title: Cloning, expression, and pharmacological characterization of a novel human histamine receptor.

Journal: Molecular pharmacology20010301

Title: Cloning and characterization of a novel human histamine receptor.

Journal: The Journal of pharmacology and experimental therapeutics20010301

Title: Histamine H1 and H2 receptor antagonists accelerate skin barrier repair and prevent epidermal hyperplasia induced by barrier disruption in a dry environment.

Journal: The Journal of investigative dermatology20010201

Title: H3 receptor-mediated inhibition of intestinal acetylcholine release: pharmacological characterization of signal transduction pathways.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20010201

Title: The rat H3 receptor: gene organization and multiple isoforms.

Journal: Biochemical and biophysical research communications20010112

Title: Histamine H(3) receptors depress synaptic transmission in the corticostriatal pathway.

Journal: Neuropharmacology20010101

Title: Cortical acetylcholine release elicited by stimulation of histamine H1 receptors in the nucleus basalis magnocellularis: a dual-probe microdialysis study in the freely moving rat.

Journal: The European journal of neuroscience20010101

Title: Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domain.

Journal: British journal of pharmacology20001201

Title: Molecular cloning and characterization of a novel type of histamine receptor preferentially expressed in leukocytes.

Journal: The Journal of biological chemistry20001124

Title: Identification of a histamine H(3)-like receptor in the zebrafish (Danio rerio) brain.

Journal: Journal of neurochemistry20000801

Title: Cloning of rat histamine H(3) receptor reveals distinct species pharmacological profiles.

Journal: The Journal of pharmacology and experimental therapeutics20000601

Title: Effects of histamine H3 receptor agonists and antagonists on cognitive performance and scopolamine-induced amnesia.

Journal: Behavioural brain research19991001

Title: Therapeutic doses of theophylline exert proconvulsant effects in developing mice.

Journal: Brain & development19970901

Title: Inhibitory H3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats.

Journal: Naunyn-Schmiedeberg's archives of pharmacology19970201

Title: Effect of adenosine and histamine receptor stimulation on canine histamine release to pentagastrin.

Journal: Digestion19970101

Title: Thioperamide, the selective histamine H3 receptor antagonist, attenuates stimulant-induced locomotor activity in the mouse.

Journal: European journal of pharmacology19940701

Title: Modulation of the intracellular and H3-histamine receptors and chemically-induced seizures in mice.

Journal: Agents and actions19940601

Title: Identification of two H3-histamine receptor subtypes.

Journal: Molecular pharmacology19901101

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