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106325-08-0,MFCD01310636
Catalog No.:AA019DHU

106325-08-0 | 1-[[(2S,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl]-1,2,4-triazole

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5g
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10g
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25g
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100g
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA019DHU
Chemical Name:
1-[[(2S,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl]-1,2,4-triazole
CAS Number:
106325-08-0
Molecular Formula:
C17H13ClFN3O
Molecular Weight:
329.7560
MDL Number:
MFCD01310636
SMILES:
Fc1ccc(cc1)C1(Cn2cncn2)OC1c1ccccc1Cl
Properties
Computed Properties
 
Complexity:
421  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
3.2  

Literature

Title: Mixture effects of two plant protection products in liver cell lines.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180201

Title: Hepatotoxic combination effects of three azole fungicides in a broad dose range.

Journal: Archives of toxicology 20180101

Title: Mixture effects of azole fungicides on the adrenal gland in a broad dose range.

Journal: Toxicology 20170615

Title: Combination effects of azole fungicides in male rats in a broad dose range.

Journal: Toxicology 20160429

Title: Hepatotoxic effects of (tri)azole fungicides in a broad dose range.

Journal: Archives of toxicology 20151101

Title: Differential gene expression patterns in developing sexually dimorphic rat brain regions exposed to antiandrogenic, estrogenic, or complex endocrine disruptor mixtures: glutamatergic synapses as target.

Journal: Endocrinology 20150401

Title: Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendium.

Journal: PloS one 20150101

Title: Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium.

Journal: Nuclear receptor signaling 20150101

Title: Combination effects of (tri)azole fungicides on hormone production and xenobiotic metabolism in a human placental cell line.

Journal: International journal of environmental research and public health 20140901

Title: Concordance of transcriptional and apical benchmark dose levels for conazole-induced liver effects in mice.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20131101

Title: Persistent developmental toxicity in rat offspring after low dose exposure to a mixture of endocrine disrupting pesticides.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20120901

Title: The hepatocarcinogenic conazoles: cyproconazole, epoxiconazole, and propiconazole induce a common set of toxicological and transcriptional responses.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120501

Title: Stereoselective dissipation of epoxiconazole in grape (Vitis vinifera cv. Kyoho) and soil under field conditions.

Journal: Chemosphere 20120501

Title: Prenatal epoxiconazole exposure effects on rat postnatal development.

Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20120401

Title: Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus.

Journal: PloS one 20120101

Title: Enantiomeric separation of triazole fungicides with 3-μm and 5-μml particle chiral columns by reverse-phase high-performance liquid chromatography.

Journal: Chirality 20110701

Title: Selected pesticides adsorption and desorption in substrates from artificial wetland and forest buffer.

Journal: Environmental toxicology and chemistry 20110701

Title: Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola.

Journal: PloS one 20110101

Title: Endocrine disrupting effects in vitro of conazole antifungals used as pesticides and pharmaceuticals.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20101201

Title: Mixture effects of endocrine disrupting compounds in vitro.

Journal: International journal of andrology 20100401

Title: Combined exposure to endocrine disrupting pesticides impairs parturition, causes pup mortality and affects sexual differentiation in rats.

Journal: International journal of andrology 20100401

Title: Comparative study of three analysis methods (TTGE, flow cytometry and HPLC) for xenobiotic impact assessment on phytoplankton communities.

Journal: Ecotoxicology (London, England) 20090401

Title: Investigations into the source of two fungicides measured in the air for 24 hours following application to a cereal crop.

Journal: Communications in agricultural and applied biological sciences 20090101

Title: Epoxiconazole causes changes in testicular histology and sperm production in the Japanese quail (Coturnix coturnix japonica).

Journal: Environmental toxicology and chemistry 20081101

Title: In-situ microcosms, a tool for assessment of pesticide impacts on oyster spat (Crassostrea gigas).

Journal: Ecotoxicology (London, England) 20080501

Title: Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.

Journal: Chemical research in toxicology 20080401

Title: Endocrine-disrupting activities in vivo of the fungicides tebuconazole and epoxiconazole.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20071201

Title: Method of fast trace microanalysis of the chiral pesticides epoxiconazole and novaluron in soil samples using off-line flow-through extraction and on-column direct large volume injection in reversed-phase high performance liquid chromatography.

Journal: Journal of separation science 20071201

Title: [Behaviour azole fungicide and fluconazole in Cryptococcus neoformans clinical and environmental isolates].

Journal: Revista da Sociedade Brasileira de Medicina Tropical 20070101

Title: Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles.

Journal: Toxicology 20061110

Title: Influence of pH on the stereoselective degradation of the fungicides epoxiconazole and cyproconazole in soils.

Journal: Environmental science & technology 20060901

Title: Cuticular uptake of xenobiotics into living plants. Part 2: influence of the xenobiotic dose on the uptake of bentazone, epoxiconazole and pyraclostrobin, applied in the presence of various surfactants, into Chenopodium album, Sinapis alba and Triticum aestivum leaves.

Journal: Pest management science 20060701

Title: Mechanisms of cuticular uptake of xenobiotics into living plants: evaluation of a logistic-kinetic penetration model.

Journal: Journal of agricultural and food chemistry 20060419

Title: Influence of the spraying system on fungicides distribution on wheat plants.

Journal: Communications in agricultural and applied biological sciences 20060101

Title: Fate of epoxiconazole and kresoxim-methyl in wheat according to time of application.

Journal: Communications in agricultural and applied biological sciences 20050101

Title: Individual and combined effects of dosages of azoxystrobin and epoxiconazole in wheat.

Journal: Communications in agricultural and applied biological sciences 20050101

Title: Mechanisms of cuticular uptake of xenobiotics into living plants: 1. Influence of xenobiotic dose on the uptake of three model compounds applied in the absence and presence of surfactants into Chenopodium album, Hedera helix and Stephanotis floribunda leaves.

Journal: Pest management science 20041101

Title: First detection of resistance to QoI fungicides in Mycosphaerella graminicola on winter wheat in Belgium.

Journal: Communications in agricultural and applied biological sciences 20030101

Title: Liquid chromatographic method development for determination of fungicide epoxiconazole enantiomers by achiral and chiral column switching technique in water and soil.

Journal: Journal of chromatography. A 20020614

Title: Quantitative PCR monitoring of the effect of azoxystrobin treatments on Mycosphaerella graminicola epidemics in the field.

Journal: Pest management science 20020301

Title: Impact of fungicides on active oxygen species and antioxidant enzymes in spring barley (Hordeum vulgare L.) exposed to ozone.

Journal: Environmental pollution (Barking, Essex : 1987) 20020101

Title: Impact of strobilurins on physiology and yield formation of wheat.

Journal: Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) 20020101

Title: Dissipation of epoxiconazole in the paddy field under subtropical conditions of Taiwan.

Journal: Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20010701

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Tags:106325-08-0 Molecular Formula|106325-08-0 MDL|106325-08-0 SMILES|106325-08-0 1-[[(2S,3S)-3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl]-1,2,4-triazole