106562-32-7,MFCD00081051
Catalog No.:AA003892

106562-32-7 | 7-Amino-4-methyl-3-coumarinylacetic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
25mg
≥90%
in stock  
$46.00   $32.00
- +
50mg
>95.0%(T)(HPLC)
in stock  
$56.00   $40.00
- +
100mg
95%
in stock  
$69.00   $48.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA003892
Chemical Name:
7-Amino-4-methyl-3-coumarinylacetic acid
CAS Number:
106562-32-7
Molecular Formula:
C12H11NO4
Molecular Weight:
233.2200
MDL Number:
MFCD00081051
SMILES:
OC(=O)Cc1c(=O)oc2c(c1C)ccc(c2)N
Properties
Computed Properties
 
Complexity:
388  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
0.6  

Downstream Synthesis Route
57260-73-8    106562-32-7   
{2-2-(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)-acetylamino-ethyl}-carbamicacidtert-butylester 

[1]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

[1]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

[1]Ou,Pan;Zhang,Ruilong;Liu,Zhengjie;Tian,Xiaohe;Han,Guangmei;Liu,Bianhua;Hu,Zhangjun;Zhang,Zhongping[AngewandteChemie-InternationalEdition,2019,vol.58,#8,p.2261-2265][Angew.Chem.,2019,vol.131,#8,p.2283-2287,5]

[2]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

[1]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

106562-32-7   
N'-{3-(2-Amino-ethylcarbamoyl)-methyl-4-methyl-2-oxo-2H-chromen-7-yl}-N''-(4-cyano-phenyl)-guanidino-aceticacid 

[1]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

[2]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

Literature

Title: Determination of antimicrobial activity and resistance to oxidation of moringa peregrina seed oil.

Journal: Molecules (Basel, Switzerland) 20120224

Title: Plasmalemmal Na+/Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes.

Journal: ASN neuro 20120101

Title: Rapid accumulation of CD14+CD11c+ dendritic cells in gut mucosa of celiac disease after in vivo gluten challenge.

Journal: PloS one 20120101

Title: Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models.

Journal: Chemistry & biology 20101124

Title: Notch and Wnt signaling mediated rod photoreceptor regeneration by Müller cells in adult mammalian retina.

Journal: PloS one 20100101

Title: Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated beta-cell failure in fulminant type 1 diabetes.

Journal: Diabetes 20091001

Title: A Phos-tag-based fluorescence resonance energy transfer system for the analysis of the dephosphorylation of phosphopeptides.

Journal: Analytical biochemistry 20090515

Title: Characterisation of early mucosal and neuronal lesions following Shigella flexneri infection in human colon.

Journal: PloS one 20090101

Title: Micropit: A New Cell Culturing Approach for Characterization of Solitary Astrocytes and Small Networks of these Glial Cells.

Journal: Frontiers in neuroengineering 20080101

Title: Synthesis of Abeta[1-42] and its derivatives with improved efficiency.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20070201

Title: Substrate activity screening (SAS): a general procedure for the preparation and screening of a fragment-based non-peptidic protease substrate library for inhibitor discovery.

Journal: Nature protocols 20070101

Title: Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels.

Journal: Respiratory research 20060101

Title: Synthesis and fluorescent labeling of beta-amyloid peptides.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20010801

Title: Kinetic preference for oriented DNA binding by the yeast TATA-binding protein TBP.

Journal: Biochemistry 20010529

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Tags:106562-32-7 Molecular Formula|106562-32-7 MDL|106562-32-7 SMILES|106562-32-7 7-Amino-4-methyl-3-coumarinylacetic acid
Catalog No.: AA003892
106562-32-7,MFCD00081051
106562-32-7 | 7-Amino-4-methyl-3-coumarinylacetic acid
Pack Size: 25mg
Purity: ≥90%
in stock
$46.00 $32.00
Pack Size: 50mg
Purity: >95.0%(T)(HPLC)
in stock
$56.00 $40.00
Pack Size: 100mg
Purity: 95%
in stock
$69.00 $48.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA003892
Chemical Name: 7-Amino-4-methyl-3-coumarinylacetic acid
CAS Number: 106562-32-7
Molecular Formula: C12H11NO4
Molecular Weight: 233.2200
MDL Number: MFCD00081051
SMILES: OC(=O)Cc1c(=O)oc2c(c1C)ccc(c2)N
Properties
Complexity: 388  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 17  
Hydrogen Bond Acceptor Count: 5  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 0.6  
Downstream Synthesis Route
57260-73-8    106562-32-7   
{2-2-(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)-acetylamino-ethyl}-carbamicacidtert-butylester 

[1]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

122148-91-8    106562-32-7    207118-52-3 

[1]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

113721-84-9    106562-32-7 

[1]Ou,Pan;Zhang,Ruilong;Liu,Zhengjie;Tian,Xiaohe;Han,Guangmei;Liu,Bianhua;Hu,Zhangjun;Zhang,Zhongping[AngewandteChemie-InternationalEdition,2019,vol.58,#8,p.2261-2265][Angew.Chem.,2019,vol.131,#8,p.2283-2287,5]

[2]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

591-27-5    106562-32-7 

[1]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

106562-32-7   
N'-{3-(2-Amino-ethylcarbamoyl)-methyl-4-methyl-2-oxo-2H-chromen-7-yl}-N''-(4-cyano-phenyl)-guanidino-aceticacid 

[1]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

[2]Feng,Yangbo;Burgess,Kevin;Pledger,David;Cairns,Nick;Linthicum,D.Scott[BioorganicandMedicinalChemistryLetters,1998,vol.8,#7,p.881-884]

Literature fold

Title: Determination of antimicrobial activity and resistance to oxidation of moringa peregrina seed oil.

Journal: Molecules (Basel, Switzerland)20120224

Title: Plasmalemmal Na+/Ca2+ exchanger modulates Ca2+-dependent exocytotic release of glutamate from rat cortical astrocytes.

Journal: ASN neuro20120101

Title: Rapid accumulation of CD14+CD11c+ dendritic cells in gut mucosa of celiac disease after in vivo gluten challenge.

Journal: PloS one20120101

Title: Identification and evaluation of small molecule pan-caspase inhibitors in Huntington's disease models.

Journal: Chemistry & biology20101124

Title: Notch and Wnt signaling mediated rod photoreceptor regeneration by Müller cells in adult mammalian retina.

Journal: PloS one20100101

Title: Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated beta-cell failure in fulminant type 1 diabetes.

Journal: Diabetes20091001

Title: A Phos-tag-based fluorescence resonance energy transfer system for the analysis of the dephosphorylation of phosphopeptides.

Journal: Analytical biochemistry20090515

Title: Characterisation of early mucosal and neuronal lesions following Shigella flexneri infection in human colon.

Journal: PloS one20090101

Title: Micropit: A New Cell Culturing Approach for Characterization of Solitary Astrocytes and Small Networks of these Glial Cells.

Journal: Frontiers in neuroengineering20080101

Title: Synthesis of Abeta[1-42] and its derivatives with improved efficiency.

Journal: Journal of peptide science : an official publication of the European Peptide Society20070201

Title: Substrate activity screening (SAS): a general procedure for the preparation and screening of a fragment-based non-peptidic protease substrate library for inhibitor discovery.

Journal: Nature protocols20070101

Title: Spinal afferent neurons projecting to the rat lung and pleura express acid sensitive channels.

Journal: Respiratory research20060101

Title: Synthesis and fluorescent labeling of beta-amyloid peptides.

Journal: Journal of peptide science : an official publication of the European Peptide Society20010801

Title: Kinetic preference for oriented DNA binding by the yeast TATA-binding protein TBP.

Journal: Biochemistry20010529

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