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106740-09-4,MFCD18428020
Catalog No.:AA007BS1

106740-09-4 | GYY 4137

Pack Size
Purity
Availability
Price(USD)
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10mg
≥95%
in stock  
$88.00   $61.00
- +
25mg
≥95%
in stock  
$200.00   $140.00
- +
50mg
≥95%
in stock  
$335.00   $234.00
- +
100mg
≥95%
in stock  
$625.00   $437.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007BS1
Chemical Name:
GYY 4137
CAS Number:
106740-09-4
Molecular Formula:
C15H25N2O3PS2
Molecular Weight:
376.4744
MDL Number:
MFCD18428020
SMILES:
C1COCC[NH2+]1.COc1ccc(cc1)P(=S)(N1CCOCC1)[S-]
Properties
Computed Properties
 
Complexity:
316  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  

Literature

Title: Hydrogen sulfide pretreatment improves mitochondrial function in myocardial hypertrophy via a SIRT3-dependent manner.

Journal: British journal of pharmacology 20180401

Title: Hydrogen sulfide in paraventricular nucleus attenuates blood pressure by regulating oxidative stress and inflammatory cytokines in high salt-induced hypertension.

Journal: Toxicology letters 20170315

Title: Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression.

Journal: Pigment cell & melanoma research 20150101

Title: A new slow releasing, H₂S generating compound, GYY4137 relaxes spontaneous and oxytocin-stimulated contractions of human and rat pregnant myometrium.

Journal: PloS one 20120101

Title: Hydrogen sulfide inhibits proliferation and release of IL-8 from human airway smooth muscle cells.

Journal: American journal of respiratory cell and molecular biology 20111001

Title: Hydrogen sulfide effects on stomatal apertures.

Journal: Plant signaling & behavior 20111001

Title: The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo.

Journal: PloS one 20110101

Title: [Effect of synthesized GYY4137, a slowly releasing hydrogen sulfide donor, on cell viability and distribution of hydrogen sulfide in mice].

Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20101018

Title: GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat.

Journal: Free radical biology & medicine 20090701

Title: Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137): new insights into the biology of hydrogen sulfide.

Journal: Circulation 20080506

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