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1071000-98-0,MFCD18382097
Catalog No.:AA008SP2

1071000-98-0 | FKGK 11

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$100.00   $70.00
- +
5mg
≥98%
in stock  
$335.00   $234.00
- +
10mg
≥98%
in stock  
$558.00   $390.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008SP2
Chemical Name:
FKGK 11
CAS Number:
1071000-98-0
Molecular Formula:
C13H13F5O
Molecular Weight:
280.2337
MDL Number:
MFCD18382097
SMILES:
O=C(C(C(F)(F)F)(F)F)CCCCc1ccccc1
Properties
Computed Properties
 
Complexity:
292  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
6  
XLogP3:
4.5  

Literature

Title: Group VIA phospholipase A2 is a target for vasopressin signaling in the thick ascending limb.

Journal: American journal of physiology. Renal physiology 20120401

Title: Combination therapy of an inhibitor of group VIA phospholipase A2 with paclitaxel is highly effective in blocking ovarian cancer development.

Journal: The American journal of pathology 20110701

Title: Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2.

Journal: Journal of medicinal chemistry 20100513

Title: Synthesis of polyfluoro ketones for selective inhibition of human phospholipase A2 enzymes.

Journal: Journal of medicinal chemistry 20081225

Title: Intracellular phospholipase A(2) group IVA and group VIA play important roles in Wallerian degeneration and axon regeneration after peripheral nerve injury.

Journal: Brain : a journal of neurology 20081001

Title: Kokotos G, et al. Potent and selective fluoroketone inhibitors of group VIA calcium-independent phospholipase A2. J Med Chem. 2010 May 13;53(9):3602-10.

Title: Yan Xu, et al. Abstract 3525: Targeting Group VIA phospholipase A2 using small molecules for ovarian cancer treatment. Cancer Res (2011) 71 (8_Supplement): 3525.

Title: López-Vales R, et al. Intracellular phospholipase A(2) group IVA and group VIA play important roles in Wallerian degeneration and axon regeneration after peripheral nerve injury. Brain. 2008 Oct;131(Pt 10):2620-31.

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Tags:1071000-98-0 Molecular Formula|1071000-98-0 MDL|1071000-98-0 SMILES|1071000-98-0 FKGK 11