Home Other Building Blocks 1082954-71-9
1082954-71-9,MFCD18086882
Catalog No.:AA007UT3

1082954-71-9 | A 987306

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10mg
≥98%(HPLC)
in stock  
$500.00   $350.00
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50mg
≥98%(HPLC)
in stock  
$1,832.00   $1,283.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA007UT3
Chemical Name:
A 987306
CAS Number:
1082954-71-9
Molecular Formula:
C18H25N5O
Molecular Weight:
327.4240
MDL Number:
MFCD18086882
SMILES:
Nc1nc(N2CCNCC2)c2c(n1)C1=C(CC2)O[C@H]2[C@@H]1CCCC2
Properties
Computed Properties
 
Complexity:
518  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
1.3  

Literature

Title: Ligand based design of novel histamine H₄ receptor antagonists; fragment optimization and analysis of binding kinetics.

Journal: Bioorganic & medicinal chemistry letters 20120101

Title: cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.

Journal: Journal of medicinal chemistry 20081127

Title: cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro,3-hquinazolin-2-amine (A-987306), A New Histamine H4R Antagonist that Blocks Pain Responses against Carrageenan-Induced HyperalgesiaJ. Med. Chem., 2008, 51 (22), pp 7094-7098

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Tags:1082954-71-9 Molecular Formula|1082954-71-9 MDL|1082954-71-9 SMILES|1082954-71-9 A 987306