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108885-68-3,MFCD30725004
Catalog No.:AA008YS9

108885-68-3 | Taccalonolide A

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50mg
95%
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$1,136.00   $795.00
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Technical Information
Catalog Number:
AA008YS9
Chemical Name:
Taccalonolide A
CAS Number:
108885-68-3
Molecular Formula:
C36H46O14
Molecular Weight:
702.7420
MDL Number:
MFCD30725004
SMILES:
CC(=O)O[C@H]1[C@H]2[C@@H]([C@@H](O)C(=O)[C@@H]3[C@]2(C)[C@@H](OC(=O)C)[C@H]2O[C@H]2C3)[C@H]2[C@@]([C@H]1OC(=O)C)(C)[C@H]1[C@H](C)C=C3[C@]([C@@H]1[C@@H]2OC(=O)C)(C)[C@](C)(O)C(=O)O3
Properties

Literature

Title: Tinley TL, et al. Taccalonolides E and A: Plant -derived steroids with microtubule-stabilizing activity. Cancer Res. 2003 Jun 15;63(12):3211-20.

Title: Risinger AL, et al. Taccalonolides: Novel microtubule stabilizers with clinical potential. Cancer Lett. 2010 May 1;291(1):14-9.

Title: Risinger AL, et al. The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms. Cancer Res. 2008 Nov 1;68(21):8881-8.

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