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Home Other Building Blocks 1093100-40-3
1093100-40-3,MFCD22571725
Catalog No.:AA008TBV

1093100-40-3 | B-Raf inhibitor 1

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
in stock  
$245.00   $172.00
- +
10mg
in stock  
$375.00   $263.00
- +
50mg
in stock  
$1,211.00   $848.00
- +
100mg
in stock  
$2,059.00   $1,442.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008TBV
Chemical Name:
B-Raf inhibitor 1
CAS Number:
1093100-40-3
Molecular Formula:
C26H19ClN8
Molecular Weight:
478.9357
MDL Number:
MFCD22571725
SMILES:
Clc1ccc(cc1)Nc1nccc2c1ccc(c2Nc1ncccc1c1ncnc2c1[nH]cn2)C
Properties
Computed Properties
 
Complexity:
690  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
5.6  

Downstream Synthesis Route
Literature

Title: Conformation-specific effects of Raf kinase inhibitors.

Journal: Journal of medicinal chemistry 20120913

Title: Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.

Journal: Journal of medicinal chemistry 20091022

Title: Wang X, et al. Conformation-specific effects of Raf kinase inhibitors. J Med Chem. 2012 Sep 13;55(17):7332-41.

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SDS
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