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1093108-50-9,MFCD28144681
Catalog No.:AA00957O

1093108-50-9 | AP-761

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$306.00   $214.00
- +
5mg
98% (HPLC)
in stock  
$573.00   $401.00
- +
10mg
98% (HPLC)
in stock  
$926.00   $648.00
- +
25mg
98% (HPLC)
in stock  
$1,889.00   $1,323.00
- +
50mg
98% (HPLC)
in stock  
$3,175.00   $2,223.00
- +
100mg
98% (HPLC)
in stock  
$5,449.00   $3,814.00
- +
500mg
98% (HPLC)
in stock  
$17,455.00   $12,219.00
- +
1000mg
98% (HPLC)
in stock  
$27,894.00   $19,526.00
- +
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00957O
Chemical Name:
AP-761
CAS Number:
1093108-50-9
Molecular Formula:
C25H26F3N5O3
Molecular Weight:
501.5008
MDL Number:
MFCD28144681
SMILES:
OC(=O)Cc1c(nc(nc1N(C)C)Cc1ccc(cc1)NC(=O)c1ccc(cc1)C(F)(F)F)N(C)C
Properties

Literature

Title: Boehme SA, et al. A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation. Int Immunol. 2009 Jan;21(1):81-93.

Title: Miller D, et al. A randomized study of BI 671800, a CRTH2 antagonist, as add-on therapy in poorly controlled asthma. Allergy Asthma Proc. 2017 Mar 1;38(2):157-164.

Title: Lukacs NW, et al. CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation. Am J Physiol Lung Cell Mol Physiol. 2008 Nov;295(5):L767-79.

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SDS
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