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1093119-54-0,MFCD30496700
Catalog No.:AA01EAYE

1093119-54-0 | MKC3946

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$11.00   $8.00
- +
5mg
97%
in stock  
$29.00   $21.00
- +
10mg
97%
in stock  
$48.00   $34.00
- +
25mg
97%
in stock  
$95.00   $67.00
- +
50mg
97%
in stock  
$162.00   $114.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01EAYE
Chemical Name:
MKC3946
CAS Number:
1093119-54-0
Molecular Formula:
C21H20N2O3S
Molecular Weight:
380.4601
MDL Number:
MFCD30496700
SMILES:
O=Cc1c(O)ccc2c1ccc(c2)c1ccc(s1)C(=O)N1CCN(CC1)C
Properties
Computed Properties
 
Complexity:
552  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3.8  

Downstream Synthesis Route
Literature

Title: Sun H, et al. Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia. Oncotarget. 2016 Apr 5;7(14):18736-49

Title: Zhang L, et al. IRE1 inhibition perturbs the unfolded protein response in a pancreatic β-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis. BMC Cell Biol. 2014 Jul 10;15:29.

Title: Mimura N, et al. Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma. Blood. 2012 Jun 14;119(24):5772-81

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SDS
Tags:1093119-54-0 Molecular Formula|1093119-54-0 MDL|1093119-54-0 SMILES|1093119-54-0 MKC3946