Title: Naringin enhances endothelial progenitor cell (EPC) proliferation and tube formation capacity through the CXCL12/CXCR4/PI3K/Akt signaling pathway.
Journal: Chemico-biological interactions 20180425
Title: Inhibitory effects of 3,3'-diindolylmethane on epithelial-mesenchymal transition induced by endocrine disrupting chemicals in cellular and xenograft mouse models of breast cancer.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20171101
Title: A Novel CXCR4 Antagonist CX549 Induces Neuroprotection in Stroke Brain.
Journal: Cell transplantation 20170401
Title: Resveratrol suppresses vascular endothelial growth factor secretion via inhibition of CXC-chemokine receptor 4 expression in ARPE-19 cells.
Journal: Molecular medicine reports 20150701
Title: Expression and regulation of stromal cell-derived factor-1 (SDF1) and chemokine CXC motif receptor 4 (CXCR4) in equine and bovine preovulatory follicles.
Journal: Molecular and cellular endocrinology 20140625
Title: Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity.
Journal: Toxicology 20131215
Title: The effect of various concentrations of iodine potassium iodide on the antimicrobial properties of mineral trioxide aggregate--a pilot study.
Journal: Dental traumatology : official publication of International Association for Dental Traumatology 20121201
Title: Chemokine receptor antagonists.
Journal: Journal of medicinal chemistry 20121126
Title: Plerixafor plus G-CSF in combination with chemotherapy for stem cell mobilization in a pediatric patient with Ewing's sarcoma.
Journal: Journal of clinical apheresis 20121101
Title: Long-term administration of AMD3100, an antagonist of SDF-1/CXCR4 signaling, alters fracture repair.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20121101
Title: CXCR4 chemokine receptor antagonists: nickel(II) complexes of configurationally restricted macrocycles.
Journal: Dalton transactions (Cambridge, England : 2003) 20121007
Title: Efficacy and safety of hematopoietic stem cell remobilization with plerixafor+G-CSF in adult patients with germ cell tumors.
Journal: Bone marrow transplantation 20121001
Title: Inhibition of stromal CXCR4 impairs development of lung metastases.
Journal: Cancer immunology, immunotherapy : CII 20121001
Title: Plerixafor plus granulocyte colony-stimulating factor versus placebo plus granulocyte colony-stimulating factor for mobilization of CD34(+) hematopoietic stem cells in patients with multiple myeloma and low peripheral blood CD34(+) cell count: results of a subset analysis of a randomized trial.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20121001
Title: Effects of plerixafor in combination with BCR-ABL kinase inhibition in a murine model of CML.
Journal: Blood 20120927
Title: Novel agents and approaches for stem cell mobilization in normal donors and patients.
Journal: Bone marrow transplantation 20120901
Title: Allosteric modulators of rhodopsin-like G protein-coupled receptors: opportunities in drug development.
Journal: Pharmacology & therapeutics 20120901
Title: Plerixafor, a CXCR4 antagonist, mitigates skin radiation-induced injury in mice.
Journal: Radiation research 20120901
Title: Vinorelbine inhibits angiogenesis and 95D migration via reducing hypoxic fibroblast stromal cell-derived factor 1 secretion.
Journal: Experimental biology and medicine (Maywood, N.J.) 20120901
Title: Preemptive dosing of plerixafor given to poor stem cell mobilizers on day 5 of G-CSF administration.
Journal: Bone marrow transplantation 20120801
Title: European data on stem cell mobilization with plerixafor in non-Hodgkin's lymphoma, Hodgkin's lymphoma and multiple myeloma patients. A subgroup analysis of the European Consortium of stem cell mobilization.
Journal: Bone marrow transplantation 20120801
Title: Plerixafor in AL amyloidosis: improved graft composition and faster lymphocyte recovery after auto-SCT in patient with end-stage renal-disease.
Journal: Bone marrow transplantation 20120801
Title: Systematic review of randomized controlled trials of hematopoietic stem cell mobilization strategies for autologous transplantation for hematologic malignancies.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120801
Title: Blood graft lymphocyte subsets after plerixafor injection in non-Hodgkin's lymphoma patients mobilizing poorly with chemotherapy plus granulocyte-colony-stimulating factor.
Journal: Transfusion 20120801
Title: Progenitor cell mobilizing treatments prevent experimental transplant arteriosclerosis.
Journal: The Journal of surgical research 20120801
Title: Who should be really considered as a poor mobilizer in the plerixafor era?
Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20120801
Title: Blood graft composition after plerixafor injection in patients with NHL.
Journal: European journal of haematology 20120801
Title: Plerixafor use in patients with previous mobilization failure: A multicenter experience.
Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20120801
Title: CXCR4 inhibition with AMD3100 sensitizes prostate cancer to docetaxel chemotherapy.
Journal: Neoplasia (New York, N.Y.) 20120801
Title: The use of plerixafor in harvesting autologous stem cells in the pediatric setting.
Journal: Pediatric blood & cancer 20120715
Title: Higher BMI is not a barrier to stem cell mobilization with standard doses of plerixafor and G-CSF.
Journal: Bone marrow transplantation 20120701
Title: High white blood cell concentration in the peripheral blood stem cell product can induce seizures during infusion of autologous peripheral blood stem cells.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120701
Title: Kinetics of blood CD34(+) cells after chemotherapy plus G-CSF in poor mobilizers: implications for pre-emptive plerixafor use.
Journal: Annals of hematology 20120701
Title: Retrospective comparison of filgrastim plus plerixafor to other regimens for remobilization after primary mobilization failure: clinical and economic outcomes.
Journal: American journal of hematology 20120701
Title: Plerixafor as first- and second-line strategies for autologous stem cell mobilization in patients with non-Hodgkin's lymphoma or multiple myeloma.
Journal: Pharmacotherapy 20120701
Title: CXCR4 activation maintains a stem cell population in tamoxifen-resistant breast cancer cells through AhR signalling.
Journal: British journal of cancer 20120626
Title: Pharmacophore-based small molecule CXCR4 ligands.
Journal: Bioorganic & medicinal chemistry letters 20120615
Title: Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation.
Journal: Bone marrow transplantation 20120601
Title: Exposure to ambient air fine particulate matter prevents VEGF-induced mobilization of endothelial progenitor cells from the bone marrow.
Journal: Environmental health perspectives 20120601
Title: Pre-emptive plerixafor injection increases blood neutrophil, lymphocyte and monocyte counts in addition to CD34+ counts in patients with non-Hodgkin lymphoma mobilizing poorly with chemotherapy plus G-CSF: potential implications for apheresis and graft composition.
Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20120601
Title: Inhibition of CXCR4 in CML cells disrupts their interaction with the bone marrow microenvironment and sensitizes them to nilotinib.
Journal: Leukemia 20120501
Title: α-Tocopherol succinate- and AMD3100-mobilized progenitors mitigate radiation-induced gastrointestinal injury in mice.
Journal: Experimental hematology 20120501
Title: A phase 1/2 study of chemosensitization with the CXCR4 antagonist plerixafor in relapsed or refractory acute myeloid leukemia.
Journal: Blood 20120426
Title: A risk-based approach to optimize autologous hematopoietic stem cell (HSC) collection with the use of plerixafor.
Journal: Bone marrow transplantation 20120401
Title: Preemptive use of plerixafor in difficult-to-mobilize patients: an emerging concept.
Journal: Transfusion 20120401
Title: AMD3100 disrupts the cross-talk between chronic lymphocytic leukemia cells and a mesenchymal stromal or nurse-like cell-based microenvironment: pre-clinical evidence for its association with chronic lymphocytic leukemia treatments.
Journal: Haematologica 20120401
Title: Heparan sulfate mimetics can efficiently mobilize long-term hematopoietic stem cells.
Journal: Haematologica 20120401
Title: The use of plerixafor in hematopoietic progenitor cell collection in pediatric patients: a single center experience.
Journal: Cytotherapy 20120401
Title: Expression of chemokine CXCL12 and its receptor CXCR4 in folliculostellate (FS) cells of the rat anterior pituitary gland: the CXCL12/CXCR4 axis induces interconnection of FS cells.
Journal: Endocrinology 20120401
Title: [Anti-angiogenesis effect of AMD3100 in oxygen-induced retinopathy mice].
Journal: [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20120401
Title: S1P promotes murine progenitor cell egress and mobilization via S1P1-mediated ROS signaling and SDF-1 release.
Journal: Blood 20120315
Title: Plerixafor plus granulocyte-colony stimulating factor for autologous hematopoietic stem cell mobilization in patients with metastatic neuroblastoma.
Journal: Pediatric blood & cancer 20120301
Title: Proposed definition of 'poor mobilizer' in lymphoma and multiple myeloma: an analytic hierarchy process by ad hoc working group Gruppo ItalianoTrapianto di Midollo Osseo.
Journal: Bone marrow transplantation 20120301
Title: Priming of hematopoietic progenitor cells by plerixafor and filgrastim in children with previous failure of mobilization with chemotherapy and/or cytokine treatment.
Journal: Journal of pediatric hematology/oncology 20120301
Title: Allogeneic transplantation: peripheral blood vs. bone marrow.
Journal: Current opinion in oncology 20120301
Title: The use of chemokine receptor agonists in stem cell mobilization.
Journal: Expert opinion on biological therapy 20120301
Title: Discovery of novel stem cell mobilizers that target the CXCR4 receptor.
Journal: ChemMedChem 20120206
Title: Plerixafor added to chemotherapy plus G-CSF is safe and allows adequate PBSC collection in predicted poor mobilizer patients with multiple myeloma or lymphoma.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120201
Title: Plerixafor and Filgrastim XM02 (Tevagastrim) as a first line peripheral blood stem cell mobilisation strategy in patients with multiple myeloma and lymphoma candidated to autologous bone marrow transplantation.
Journal: European journal of haematology 20120201
Title: Plerixafor for autologous peripheral blood stem cell mobilization in patients previously treated with fludarabine or lenalidomide.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120201
Title: Will the Stroma-derived Factor-1α (CXCL12)/CXCR4 Pathway Become a Major Concern for Advanced Colorectal Cancer?
Journal: Journal of the Korean Society of Coloproctology 20120201
Title: Sphingosine-1-phosphate facilitates trafficking of hematopoietic stem cells and their mobilization by CXCR4 antagonists in mice.
Journal: Blood 20120119
Title: PBSCs Sphingoling along S1P/S1P1 axis.
Journal: Blood 20120119
Title: Plerixafor for PBSC mobilisation in myeloma patients with advanced renal failure: safety and efficacy data in a series of 21 patients from Europe and the USA.
Journal: Bone marrow transplantation 20120101
Title: Efficacy and cost-benefit analysis of risk-adaptive use of plerixafor for autologous hematopoietic progenitor cell mobilization.
Journal: Transfusion 20120101
Title: Enhancement of the anti-tumor activity of therapeutic monoclonal antibodies by CXCR4 antagonists.
Journal: Leukemia & lymphoma 20120101
Title: Hematopoietic stem cell mobilization for gene therapy of adult patients with severe β-thalassemia: results of clinical trials using G-CSF or plerixafor in splenectomized and nonsplenectomized subjects.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20120101
Title: Hematopoietic recovery kinetics predicts for poor CD34+ cell mobilization after cyclophosphamide chemotherapy in multiple myeloma.
Journal: American journal of hematology 20120101
Title: In vivo imaging of ligand receptor binding with Gaussia luciferase complementation.
Journal: Nature medicine 20120101
Title: Optimizing stem cell collection through CXCR4 antagonists.
Journal: Frontiers in bioscience (Scholar edition) 20120101
Title: The effective use of plerixafor as a real-time rescue strategy for patients poorly mobilizing autologous CD34(+) cells.
Journal: Journal of clinical apheresis 20120101
Title: Dependence of acute myeloid leukemia on adhesion within the bone marrow microenvironment.
Journal: TheScientificWorldJournal 20120101
Title: CXCR4 expression in prostate cancer progenitor cells.
Journal: PloS one 20120101
Title: Economic evaluation of plerixafor for stem cell mobilization.
Journal: The American journal of managed care 20120101
Title: Successful mobilization using a combination of plerixafor and G-CSF in pediatric patients who failed previous chemomobilization with G-CSF alone and possible complications of the treatment.
Journal: Journal of hematology & oncology 20120101
Title: Structural insights from binding poses of CCR2 and CCR5 with clinically important antagonists: a combined in silico study.
Journal: PloS one 20120101
Title: Hematopoietic Stem Cell Mobilization and Homing after Transplantation: The Role of MMP-2, MMP-9, and MT1-MMP.
Journal: Biochemistry research international 20120101
Title: Efficacy and adverse effects of the antiviral compound plerixafor in feline immunodeficiency virus-infected cats.
Journal: Journal of veterinary internal medicine 20120101
Title: Plerixafor Salvage Is Safe and Effective in Hard-to-Mobilize Patients Undergoing Chemotherapy and Filgrastim-Based Peripheral Blood Progenitor Cell Mobilization.
Journal: Journal of oncology 20120101
Title: Initial assessment of the role of CXC chemokine receptor 4 after polytrauma.
Journal: Molecular medicine (Cambridge, Mass.) 20120101
Title: Acute myeloid leukemia: focus on novel therapeutic strategies.
Journal: Clinical Medicine Insights. Oncology 20120101
Title: Current knowledge on pancreatic cancer.
Journal: Frontiers in oncology 20120101
Title: Lenalidomide before and after Autologous Hematopoietic Stem Cell Transplantation in Multiple Myeloma.
Journal: Advances in hematology 20120101
Title: Autologous Hematopoietic Stem Cell Transplantation for Multiple Myeloma without Cryopreservation.
Journal: Bone marrow research 20120101
Title: Induction therapy and stem cell mobilization in patients with newly diagnosed multiple myeloma.
Journal: Stem cells international 20120101
Title: Hematopoietic stem cell mobilization: a clinical protocol.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: Hematopoietic progenitor cell collection.
Journal: Methods in molecular biology (Clifton, N.J.) 20120101
Title: [Hematopoietic stem cells mobilization: state of the art in 2011 and perspectives].
Journal: Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20111201
Title: CXCR4 antagonists in hematologic malignancies: more than just mobilizers?
Journal: The Korean journal of hematology 20111201
Title: Evaluation of a fluorescent derivative of AMD3100 and its interaction with the CXCR4 chemokine receptor.
Journal: Chembiochem : a European journal of chemical biology 20111125
Title: Acetylcholinesterase-inhibiting alkaloids from Zephyranthes concolor.
Journal: Molecules (Basel, Switzerland) 20111115
Title: The CXCR4 antagonist plerixafor is a potential therapy for myelokathexis, WHIM syndrome.
Journal: Blood 20111103
Title: The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome.
Journal: Blood 20111103
Title: How I treat patients who mobilize hematopoietic stem cells poorly.
Journal: Blood 20111027
Title: AMD3100 is a potent antagonist at CXCR4(R334X) , a hyperfunctional mutant chemokine receptor and cause of WHIM syndrome.
Journal: Journal of cellular and molecular medicine 20111001
Title: Effectiveness and cost analysis of 'just-in-time' salvage plerixafor administration in autologous transplant patients with poor stem cell mobilization kinetics.
Journal: Transfusion 20111001
Title: The effect of gp120 on morphine's antinociceptive and neurophysiological actions.
Journal: Brain, behavior, and immunity 20111001
Title: Mobilization of host stem cells enables long-term liver transplant acceptance in a strongly rejecting rat strain combination.
Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111001
Title: Beyond CD34+ cell dose: impact of method of peripheral blood hematopoietic stem cell mobilization (granulocyte-colony-stimulating factor [G-CSF], G-CSF plus plerixafor, or cyclophosphamide G-CSF/granulocyte-macrophage [GM]-CSF) on number of colony-forming unit-GM, engraftment, and Day +100 hematopoietic graft function.
Journal: Transfusion 20110901
Title: Plerixafor to rescue failing chemotherapy-based stem cell mobilization: it's not too late.
Journal: Leukemia & lymphoma 20110901
Title: Novel strategies for blood stem cell mobilization: special focus on plerixafor.
Journal: Expert opinion on biological therapy 20110901
Title: Plerixafor: a review of its use in stem-cell mobilization in patients with lymphoma or multiple myeloma.
Journal: Drugs 20110820
Title: Synthesis, gp120 binding and anti-HIV activity of fatty acid esters of 1,1-linked disaccharides.
Journal: Bioorganic & medicinal chemistry 20110815
Title: Astrocytes and pericytes cooperatively maintain a capillary-like structure composed of endothelial cells on gel matrix.
Journal: Brain research 20110811
Title: Plerixafor with and without chemotherapy in poor mobilizers: results from the German compassionate use program.
Journal: Bone marrow transplantation 20110801
Title: Successful mobilization with plerixafor and autologous hematopoietic SCT in a patient with refractory Hodgkin's lymphoma and Gaucher disease.
Journal: Bone marrow transplantation 20110801
Title: Plerixafor is effective and safe for stem cell mobilization in heavily pretreated germ cell tumor patients.
Journal: Bone marrow transplantation 20110801
Title: Transplanted CD34(+) cell dose is associated with long-term platelet count recovery following autologous peripheral blood stem cell transplant in patients with non-Hodgkin lymphoma or multiple myeloma.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110801
Title: Combination of drug therapy in acute lymphoblastic leukemia with a CXCR4 antagonist.
Journal: Leukemia 20110801
Title: Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells.
Journal: Leukemia 20110801
Title: [New molecular targets and new clinical practices for hematopoietic stem cell mobilization].
Journal: Bulletin du cancer 20110801
Title: [Development of novel agents for multiple myeloma; now and the future].
Journal: [Rinsho ketsueki] The Japanese journal of clinical hematology 20110801
Title: Plerixafor 'just in time' for stem cell mobilization in a normal donor.
Journal: Bone marrow transplantation 20110701
Title: Acrolein inhalation prevents vascular endothelial growth factor-induced mobilization of Flk-1+/Sca-1+ cells in mice.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20110701
Title: Accelerated lymphocyte reconstitution and long-term recovery after transplantation of lentiviral-transduced rhesus CD34+ cells mobilized by G-CSF and plerixafor.
Journal: Experimental hematology 20110701
Title: In and out of the niche: perspectives in mobilization of hematopoietic stem cells.
Journal: Experimental hematology 20110701
Title: Identification of prognostic factors for plerixafor-based hematopoietic stem cell mobilization.
Journal: American journal of hematology 20110701
Title: Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas.
Journal: British journal of cancer 20110607
Title: Plerixafor and G-CSF for PBSC mobilization in patients with lymphoma who failed previous attempts with G-CSF and chemotherapy: a REL (Rete Ematologica Lombarda) experience.
Journal: Leukemia research 20110601
Title: Haematopoietic stem cell mobilization with plerixafor and G-CSF in patients with multiple myeloma transplanted with autologous stem cells.
Journal: European journal of haematology 20110601
Title: Synergistic in vitro anti-HIV type 1 activity of tenofovir with carbohydrate-binding agents (CBAs).
Journal: Antiviral research 20110601
Title: Clinical and genetic features of Warts, Hypogammaglobulinemia, Infections and Myelokathexis (WHIM) syndrome.
Journal: Current molecular medicine 20110601
Title: Late afternoon dosing of plerixafor for stem cell mobilization: a practical solution.
Journal: Clinical lymphoma, myeloma & leukemia 20110601
Title: [Some research progress of CXCR4 antagonist AMD3100].
Journal: Zhongguo shi yan xue ye xue za zhi 20110601
Title: Successful mobilization of PBSCs in a healthy volunteer donor by addition of plerixafor after failure of mobilization with G-CSF alone.
Journal: Bone marrow transplantation 20110501
Title: Cost and clinical analysis of autologous hematopoietic stem cell mobilization with G-CSF and plerixafor compared to G-CSF and cyclophosphamide.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501
Title: Plerixafor and granulocyte-colony-stimulating factor (G-CSF) in patients with lymphoma and multiple myeloma previously failing mobilization with G-CSF with or without chemotherapy for autologous hematopoietic stem cell mobilization: the Austrian experience on a named patient program.
Journal: Transfusion 20110501
Title: Hematopoietic stem cell mobilization with the reversible CXCR4 receptor inhibitor plerixafor (AMD3100)-Polish compassionate use experience.
Journal: Annals of hematology 20110501
Title: Importance of blood graft characteristics in auto-SCT: implications for optimizing mobilization regimens.
Journal: Bone marrow transplantation 20110501
Title: Tanshinone IIA increases recruitment of bone marrow mesenchymal stem cells to infarct region via up-regulating stromal cell-derived factor-1/CXC chemokine receptor 4 axis in a myocardial ischemia model.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110415
Title: CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies?
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110415
Title: Growth factor and patient-adapted use of plerixafor is superior to CY and growth factor for autologous hematopoietic stem cells mobilization.
Journal: Bone marrow transplantation 20110401
Title: Characterization of hematopoietic stem cell subsets from patients with multiple myeloma after mobilization with plerixafor.
Journal: Cytotherapy 20110401
Title: Efficacy of pre-emptively used plerixafor in patients mobilizing poorly after chemomobilization: a single centre experience.
Journal: European journal of haematology 20110401
Title: A pilot study evaluating the safety and CD34+ cell mobilizing activity of escalating doses of plerixafor in healthy volunteers.
Journal: British journal of haematology 20110401
Title: Potential of CXCR4 antagonists for the treatment of metastatic lung cancer.
Journal: Expert review of anticancer therapy 20110401
Title: Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases.
Journal: PLoS pathogens 20110401
Title: Plerixafor (Mozobil) for stem cell mobilization in patients with multiple myeloma previously treated with lenalidomide.
Journal: Bone marrow transplantation 20110301
Title: The addition of plerixafor is safe and allows adequate PBSC collection in multiple myeloma and lymphoma patients poor mobilizers after chemotherapy and G-CSF.
Journal: Bone marrow transplantation 20110301
Title: CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growth.
Journal: Experimental hematology 20110301
Title: The expression of CXCR4, CXCL12 and CXCR7 in malignant pleural mesothelioma.
Journal: The Journal of pathology 20110301
Title: Addition of plerixafor to a chemotherapy plus G-CSF mobilization in hard-to-mobilize patients.
Journal: Bone marrow transplantation 20110201
Title: Blockade of CXCR4 in oral squamous cell carcinoma inhibits lymph node metastases.
Journal: European journal of cancer (Oxford, England : 1990) 20110201
Title: Importance of receptor flexibility in binding of cyclam compounds to the chemokine receptor CXCR4.
Journal: Journal of chemical information and modeling 20110124
Title: Plerixafor plus granulocyte CSF can mobilize hematopoietic stem cells from multiple myeloma and lymphoma patients failing previous mobilization attempts: EU compassionate use data.
Journal: Bone marrow transplantation 20110101
Title: Development and validation of a decision-making algorithm to guide the use of plerixafor for autologous hematopoietic stem cell mobilization.
Journal: Bone marrow transplantation 20110101
Title: The feasibility of plerixafor as a second-line stem cell mobilizing agent in children.
Journal: Journal of pediatric hematology/oncology 20110101
Title: Targeting the CXCR4-CXCL12 axis mobilizes autologous hematopoietic stem cells and prolongs islet allograft survival via programmed death ligand 1.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20110101
Title: The role of plerixafor in optimizing peripheral blood stem cell mobilization for autologous stem cell transplantation.
Journal: Leukemia 20110101
Title: The role of chemokine receptor CXCR4 in the biologic behavior of human soft tissue sarcoma.
Journal: Sarcoma 20110101
Title: Effect of chemokine receptor CXCR4 on hypoxia-induced pulmonary hypertension and vascular remodeling in rats.
Journal: Respiratory research 20110101
Title: Mobilization of hematopoietic stem cells from the bone marrow niche to the blood compartment.
Journal: Stem cell research & therapy 20110101
Title: Plerixafor for autologous CD34 cell mobilization.
Journal: Core evidence 20110101
Title: Predicting hematopoietic stem cell mobilization failure in patients with multiple myeloma: a simple method using day 1 CD34+ cell yield.
Journal: Journal of clinical apheresis 20110101
Title: Plerixafor in poor stem cell mobilizers: the Belgian Compassionate Use Program.
Journal: Acta clinica Belgica 20110101
Title: Stem cells in acute liver failure.
Journal: Advances in surgery 20110101
Title: Successful mobilization of peripheral blood stem cells in children with cancer using plerixafor (Mozobil) and granulocyte-colony stimulating factor.
Journal: Drug design, development and therapy 20110101
Title: microRNA-150 regulates mobilization and migration of bone marrow-derived mononuclear cells by targeting Cxcr4.
Journal: PloS one 20110101
Title: Identification of hepatic niche harboring human acute lymphoblastic leukemic cells via the SDF-1/CXCR4 axis.
Journal: PloS one 20110101
Title: CXCR4 antagonist AMD3100 modulates claudin expression and intestinal barrier function in experimental colitis.
Journal: PloS one 20110101
Title: Combined phytochemistry and chemotaxis assays for identification and mechanistic analysis of anti-inflammatory phytochemicals in Fallopia japonica.
Journal: PloS one 20110101
Title: Case Study in Refractory Non-Hodgkin's Lymphoma: Successful Treatment with Plerixafor.
Journal: Case reports in oncology 20110101
Title: Long-Term Outcome after Autologous Stem Cell Transplantation with Adequate Peripheral Blood Stem Cell Mobilization Using Plerixafor and G-CSF in Poor Mobilizer Lymphoma and Myeloma Patients.
Journal: Advances in hematology 20110101
Title: CXCR4 signaling regulates metastasis of chemoresistant melanoma cells by a lymphatic metastatic niche.
Journal: Cancer research 20101215
Title: Pan-histone deacetylase inhibitor panobinostat depletes CXCR4 levels and signaling and exerts synergistic antimyeloid activity in combination with CXCR4 antagonists.
Journal: Blood 20101209
Title: The peptidomimetic CXCR4 antagonist TC14012 recruits beta-arrestin to CXCR7: roles of receptor domains.
Journal: The Journal of biological chemistry 20101203
Title: Mobilization strategies in hard-to-mobilize patients with lymphoid malignancies.
Journal: European journal of haematology 20101201
Title: Recent advances on the use of the CXCR4 antagonist plerixafor (AMD3100, Mozobil™) and potential of other CXCR4 antagonists as stem cell mobilizers.
Journal: Pharmacology & therapeutics 20101201
Title: Plerixafor dosing and administration in a patient with dialysis-dependent renal failure.
Journal: The Annals of pharmacotherapy 20101201
Title: Can every patient be mobilized?
Journal: Best practice & research. Clinical haematology 20101201
Title: CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy.
Journal: British journal of cancer 20101101
Title: Chronic AMD3100 antagonism of SDF-1alpha-CXCR4 exacerbates cardiac dysfunction and remodeling after myocardial infarction.
Journal: Journal of molecular and cellular cardiology 20101001
Title: Phosphodiesterase-5 inhibitor tadalafil acts on endothelial progenitor cells by CXCR4 signalling.
Journal: Current drug delivery 20101001
Title: Stem cell mobilization is life saving in an animal model of acute liver failure.
Journal: Annals of surgery 20101001
Title: Profound blockage of CXCR4 signaling at multiple points using the synergy between plerixafor, mirtazapine, and clotrimazole as a new glioblastoma treatment adjunct.
Journal: Turkish neurosurgery 20101001
Title: Novel monocyclam derivatives as HIV entry inhibitors: Design, synthesis, anti-HIV evaluation, and their interaction with the CXCR4 co-receptor.
Journal: ChemMedChem 20100802
Title: Plerixafor and pegylated filgrastim: a case of safe and effective hematopoietic stem cell mobilization.
Journal: Bone marrow transplantation 20100801
Title: Decreased circulating progenitor cell number and failed mechanisms of stromal cell-derived factor-1alpha mediated bone marrow mobilization impair diabetic tissue repair.
Journal: Diabetes 20100801
Title: Repeated phlebotomy augments angiogenesis to improve blood flow in murine ischemic legs.
Journal: American journal of physiology. Heart and circulatory physiology 20100801
Title: Plerixafor. Only for certain patients when G-CSF stem cell mobilisation fails.
Journal: Prescrire international 20100801
Title: Evaluation of CXCR4 inhibition in the prevention and intervention model of laser-induced choroidal neovascularization.
Journal: Investigative ophthalmology & visual science 20100701
Title: A low-molecular-weight entry inhibitor of both CCR5- and CXCR4-tropic strains of human immunodeficiency virus type 1 targets a novel site on gp41.
Journal: Journal of virology 20100701
Title: Update on clinical experience with AMD3100, an SDF-1/CXCL12-CXCR4 inhibitor, in mobilization of hematopoietic stem and progenitor cells.
Journal: Current opinion in hematology 20100701
Title: Plerixafor given before the third leukapheresis to rescue an unsuccessful stem cell mobilization with CY and G-CSF.
Journal: Bone marrow transplantation 20100601
Title: Safe and effective use of plerixafor plus G-CSF in dialysis-dependent renal failure.
Journal: American journal of hematology 20100601
Title: CXCR4, a potential predictive marker for docetaxel sensitivity in gastric cancer.
Journal: Anticancer research 20100601
Title: HIV-1 tropism.
Journal: Protein & cell 20100601
Title: Molecular imaging of CXCR4 receptor expression in human cancer xenografts with [64Cu]AMD3100 positron emission tomography.
Journal: Cancer research 20100515
Title: 'Viologen' dendrimers as antiviral agents: the effect of charge number and distance.
Journal: Journal of medicinal chemistry 20100513
Title: Plerixafor (Mozobil) alone to mobilize hematopoietic stem cells from multiple myeloma patients for autologous transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100501
Title: Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex.
Journal: Leukemia 20100501
Title: Plerixafor: a peripheral blood stem cell mobilizer.
Journal: Pharmacotherapy 20100501
Title: Plerixafor: A chemokine receptor-4 antagonist for mobilization of hematopoietic stem cells for transplantation after high-dose chemotherapy for non-Hodgkin's lymphoma or multiple myeloma.
Journal: Clinical therapeutics 20100501
Title: Plerixafor (Mozobil).
Journal: The Medical letter on drugs and therapeutics 20100405
Title: Binding of multivalent anionic porphyrins to V3 loop fragments of an HIV-1 envelope and their antiviral activity.
Journal: Chemistry, an Asian journal 20100401
Title: Molecular Medicine - CHI's 17th International Tri-Conference: Mastering Medicinal Chemistry - CHI's Seventh Annual Conference.
Journal: IDrugs : the investigational drugs journal 20100401
Title: Expression and function of CXCL12/CXCR4 in rat urinary bladder with cyclophosphamide-induced cystitis.
Journal: American journal of physiology. Renal physiology 20100301
Title: Quality assessment of cellular therapies: the emerging role of molecular assays.
Journal: The Korean journal of hematology 20100301
Title: Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4) HIV-1 replication.
Journal: Journal of medicinal chemistry 20100211
Title: Mobilization of peripheral blood stem cells for autologous transplant in non-Hodgkin's lymphoma and multiple myeloma patients by plerixafor and G-CSF and detection of tumor cell mobilization by PCR in multiple myeloma patients.
Journal: Bone marrow transplantation 20100201
Title: SDF-1alpha/CXCL12 enhances GABA and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus.
Journal: Neuropharmacology 20100201
Title: Ex vivo comparison of microbicide efficacies for preventing HIV-1 genomic integration in intraepithelial vaginal cells.
Journal: Antimicrobial agents and chemotherapy 20100201
Title: Oxovanadium(IV) cyclam and bicyclam complexes: potential CXCR4 receptor antagonists.
Journal: Inorganic chemistry 20100201
Title: New Drugs2010, PART 1.
Journal: Nursing 20100201
Title: Safety and preliminary efficacy of plerixafor (Mozobil) in combination with chemotherapy and G-CSF: an open-label, multicenter, exploratory trial in patients with multiple myeloma and non-Hodgkin's lymphoma undergoing stem cell mobilization.
Journal: Bone marrow transplantation 20100101
Title: Safety and efficacy assessment of plerixafor in patients with multiple myeloma proven or predicted to be poor mobilizers, including assessment of tumor cell mobilization.
Journal: Bone marrow transplantation 20100101
Title: A pharmacokinetic study of plerixafor in subjects with varying degrees of renal impairment.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100101
Title: Long-lasting enfuvirtide carrier pentasaccharide conjugates with potent anti-human immunodeficiency virus type 1 activity.
Journal: Antimicrobial agents and chemotherapy 20100101
Title: Peripheral blood stem cell mobilization tactics.
Journal: The Annals of pharmacotherapy 20100101
Title: Plerixafor for stem cell mobilization in patients with non-Hodgkin's lymphoma and multiple myeloma.
Journal: The Annals of pharmacotherapy 20100101
Title: Alpha-tocopherol succinate protects mice from gamma-radiation by induction of granulocyte-colony stimulating factor.
Journal: International journal of radiation biology 20100101
Title: Anticancer Role of PPARgamma Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes.
Journal: PPAR research 20100101
Title: CXCR4 in clinical hematology.
Journal: Current topics in microbiology and immunology 20100101
Title: Hypoxia increases the metastatic ability of breast cancer cells via upregulation of CXCR4.
Journal: BMC cancer 20100101
Title: FDA review summary: Mozobil in combination with granulocyte colony-stimulating factor to mobilize hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation.
Journal: Oncology 20100101
Title: Breast cancer stromal fibroblasts promote the generation of CD44+CD24- cells through SDF-1/CXCR4 interaction.
Journal: Journal of experimental & clinical cancer research : CR 20100101
Title: Selective enhancement of donor hematopoietic cell engraftment by the CXCR4 antagonist AMD3100 in a mouse transplantation model.
Journal: PloS one 20100101
Title: Challenges in treating older patients with acute myeloid leukemia.
Journal: Journal of oncology 20100101
Title: Plerixafor mobilization leads to a lower ratio of CD34+ cells to total nucleated cells which results in greater storage costs.
Journal: Journal of clinical apheresis 20100101
Title: Effects of human mesenchymal stem cells on ER-positive human breast carcinoma cells mediated through ER-SDF-1/CXCR4 crosstalk.
Journal: Molecular cancer 20100101
Title: Plerixafor enables successful hematopoietic stem cell collection in an extensively pretreated patient with testicular cancer.
Journal: Acta haematologica 20100101
Title: Proteasome inhibition and its therapeutic potential in multiple myeloma.
Journal: Biologics : targets & therapy 20100101
Title: Successful stem-cell mobilization and transplantation using plerixafor in a patient with a germ cell tumor.
Journal: Hematology/oncology and stem cell therapy 20100101
Title: Booster of plerixafor can be successfully used in addition to chemotherapy-based regimen to rescue stem cell mobilization failure.
Journal: Annals of transplantation 20100101
Title: Poor hematopoietic stem cell mobilizers in multiple myeloma: a single institution experience.
Journal: Mediterranean journal of hematology and infectious diseases 20100101
Title: [New drugs for small animals in 2009].
Journal: Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere 20100101
Title: Glycosaminoglycans and syndecan-4 are involved in SDF-1/CXCL12-mediated invasion of human epitheloid carcinoma HeLa cells.
Journal: Biochimica et biophysica acta 20091201
Title: ADS-J1 inhibits human immunodeficiency virus type 1 entry by interacting with the gp41 pocket region and blocking fusion-active gp41 core formation.
Journal: Antimicrobial agents and chemotherapy 20091201
Title: Successful stem cell remobilization using plerixafor (mozobil) plus granulocyte colony-stimulating factor in patients with non-hodgkin lymphoma: results from the plerixafor NHL phase 3 study rescue protocol.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20091201
Title: Mobilization of hematopoietic stem cells into the peripheral blood.
Journal: Expert review of hematology 20091201
Title: [Stem cell harvesting after plerixafor treatment].
Journal: Ugeskrift for laeger 20091116
Title: [Mobilisation of haematopoietic stem cells with plerixafor--secondary publication].
Journal: Ugeskrift for laeger 20091102
Title: International myeloma working group (IMWG) consensus statement and guidelines regarding the current status of stem cell collection and high-dose therapy for multiple myeloma and the role of plerixafor (AMD 3100).
Journal: Leukemia 20091001
Title: Plerixafor inhibits chemotaxis toward SDF-1 and CXCR4-mediated stroma contact in a dose-dependent manner resulting in increased susceptibility of BCR-ABL+ cell to Imatinib and Nilotinib.
Journal: Leukemia & lymphoma 20091001
Title: Phase III prospective randomized double-blind placebo-controlled trial of plerixafor plus granulocyte colony-stimulating factor compared with placebo plus granulocyte colony-stimulating factor for autologous stem-cell mobilization and transplantation for patients with non-Hodgkin's lymphoma.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091001
Title: Inhibition of stromal cell-derived factor-1/CXCR4 axis for the cure of BCR-ABL positive chronic myeloid leukemia.
Journal: Leukemia & lymphoma 20091001
Title: Plerixafor (AMD3100) and granulocyte colony-stimulating factor (G-CSF) mobilize different CD34+ cell populations based on global gene and microRNA expression signatures.
Journal: Blood 20090917
Title: Extracellular calcium increases CXCR4 expression on bone marrow-derived cells and enhances pro-angiogenesis therapy.
Journal: Journal of cellular and molecular medicine 20090901
Title: Advances in mobilization for the optimization of autologous stem cell transplantation.
Journal: Leukemia & lymphoma 20090901
Title: Apolipoproteins D and E3 exert neurotrophic and synaptogenic effects in dorsal root ganglion cell cultures.
Journal: Neuroscience 20090818
Title: BIO5192, a small molecule inhibitor of VLA-4, mobilizes hematopoietic stem and progenitor cells.
Journal: Blood 20090813
Title: Bis-14-membered ring diketal diamines: synthesis and evaluation of their anti-HIV and anti-tumoral activities.
Journal: European journal of medicinal chemistry 20090801
Title: Plerixafor hydrochloride: a novel agent for the mobilization of peripheral blood stem cells.
Journal: Drugs of today (Barcelona, Spain : 1998) 20090701
Title: Modulation of cocaine-induced activity by intracerebral administration of CXCL12.
Journal: Neuroscience 20090616
Title: Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.
Journal: Blood 20090611
Title: Plerixafor and G-CSF versus placebo and G-CSF to mobilize hematopoietic stem cells for autologous stem cell transplantation in patients with multiple myeloma.
Journal: Blood 20090604
Title: Rescue from failed growth factor and/or chemotherapy HSC mobilization with G-CSF and plerixafor (AMD3100): an institutional experience.
Journal: Bone marrow transplantation 20090601
Title: Impairment of filgrastim-induced stem cell mobilization after prior lenalidomide in patients with multiple myeloma.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090601
Title: New macrocyclic amines showing activity as HIV entry inhibitors against wild type and multi-drug resistant viruses.
Journal: Molecules (Basel, Switzerland) 20090522
Title: Mantle cell lymphoma cells express high levels of CXCR4, CXCR5, and VLA-4 (CD49d): importance for interactions with the stromal microenvironment and specific targeting.
Journal: Blood 20090507
Title: AMD3100 is a CXCR7 ligand with allosteric agonist properties.
Journal: Molecular pharmacology 20090501
Title: CXCR4 mediates the homing of B cell progenitor acute lymphoblastic leukaemia cells to the bone marrow via activation of p38MAPK.
Journal: British journal of haematology 20090501
Title: CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
Journal: Blood 20090430
Title: CXCR4 chemokine receptor antagonists: perspectives in SCLC.
Journal: Expert opinion on investigational drugs 20090401
Title: Morphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neurons.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20090225
Title: Treatment with plerixafor in non-Hodgkin's lymphoma and multiple myeloma patients to increase the number of peripheral blood stem cells when given a mobilizing regimen of G-CSF: implications for the heavily pretreated patient.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090201
Title: Plerixafor.
Journal: Nature reviews. Drug discovery 20090201
Title: Plerixafor approved for autologous hematopoietic stem-cell transplantation.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090115
Title: Differential mobilization of subsets of progenitor cells from the bone marrow.
Journal: Cell stem cell 20090109
Title: CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers.
Journal: Leukemia 20090101
Title: Pharmacokinetics and pharmacodynamics of plerixafor in patients with non-Hodgkin lymphoma and multiple myeloma.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090101
Title: Plerixafor: in patients with non-Hodgkin's lymphoma or multiple myeloma.
Journal: Drugs 20090101
Title: Recent patents regarding the discovery of small molecule CXCR4 antagonists.
Journal: Expert opinion on therapeutic patents 20090101
Title: CXCR4 and mobilization of hematopoietic precursors.
Journal: Methods in enzymology 20090101
Title: Tumor biology and cancer therapy - an evolving relationship.
Journal: Cell communication and signaling : CCS 20090101
Title: A combination of granulocyte-colony-stimulating factor (G-CSF) and plerixafor mobilizes more primitive peripheral blood progenitor cells than G-CSF alone: results of a European phase II study.
Journal: Cytotherapy 20090101
Title: Targeted antagonism of CXCR4 mobilizes progenitor cells under investigation for cardiovascular disease.
Journal: Cytotherapy 20090101
Title: Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1.
Journal: BMC developmental biology 20090101
Title: Orally bioavailable isothioureas block function of the chemokine receptor CXCR4 in vitro and in vivo.
Journal: Journal of medicinal chemistry 20081225
Title: Comparison of the potential multiple binding modes of bicyclam, monocylam, and noncyclam small-molecule CXC chemokine receptor 4 inhibitors.
Journal: Molecular pharmacology 20081201
Title: Microenvironmental considerations in the application of human mesenchymal stem cells in regenerative therapies.
Journal: Biologics : targets & therapy 20081201
Title: The discovery of antiviral agents: ten different compounds, ten different stories.
Journal: Medicinal research reviews 20081101
Title: Plerixafor, a CXCR4 antagonist for the mobilization of hematopoietic stem cells.
Journal: Expert opinion on biological therapy 20081101
Title: A novel CXCR4 antagonist for hematopoietic stem cell mobilization.
Journal: Expert opinion on investigational drugs 20081101
Title: A phase II study of plerixafor (AMD3100) plus G-CSF for autologous hematopoietic progenitor cell mobilization in patients with Hodgkin lymphoma.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20081101
Title: Discovery of novel non-cyclam polynitrogenated CXCR4 coreceptor inhibitors.
Journal: ChemMedChem 20081001
Title: Impact of mobilization and remobilization strategies on achieving sufficient stem cell yields for autologous transplantation.
Journal: Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080901
Title: Curcumin modulates SDF-1alpha/CXCR4-induced migration of human retinal endothelial cells (HRECs).
Journal: Investigative ophthalmology & visual science 20080801
Title: Use of N-methylpiperazine for the preparation of piperazine-based unsymmetrical bis-ureas as anti-HIV agents.
Journal: ChemMedChem 20080701
Title: SDF-1/CXCR4 and VLA-4 interaction regulates homing in Waldenstrom macroglobulinemia.
Journal: Blood 20080701
Title: Potent synergistic anti-human immunodeficiency virus (HIV) effects using combinations of the CCR5 inhibitor aplaviroc with other anti-HIV drugs.
Journal: Antimicrobial agents and chemotherapy 20080601
Title: NeoR6 inhibits HIV-1-CXCR4 interaction without affecting CXCL12 chemotaxis activity.
Journal: Biochimica et biophysica acta 20080601
Title: Tonic activation of CXC chemokine receptor 4 in immature granule cells supports neurogenesis in the adult dentate gyrus.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080423
Title: Anti-HIV activity and resistance profile of the CXC chemokine receptor 4 antagonist POL3026.
Journal: Molecular pharmacology 20080401
Title: Stromal cell-derived factor-1 promotes bone marrow-derived cells differentiation to cardiomyocyte phenotypes in vitro.
Journal: Cell proliferation 20080401
Title: HIV-1 escape to CCR5 coreceptor antagonism through selection of CXCR4-using variants in vitro.
Journal: AIDS (London, England) 20080102
Title: Betulinic acid derivatives that target gp120 and inhibit multiple genetic subtypes of human immunodeficiency virus type 1.
Journal: Antimicrobial agents and chemotherapy 20080101
Title: 17beta-estradiol promotes breast cancer cell proliferation-inducing stromal cell-derived factor-1-mediated epidermal growth factor receptor transactivation: reversal by gefitinib pretreatment.
Journal: Molecular pharmacology 20080101
Title: Distinct efficacy of HIV-1 entry inhibitors to prevent cell-to-cell transfer of R5 and X4 viruses across a human placental trophoblast barrier in a reconstitution model in vitro.
Journal: Retrovirology 20080101
Title: Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis.
Journal: Journal of translational medicine 20080101
Title: Elevated CXCL12 expression in the bone marrow of NOD mice is associated with altered T cell and stem cell trafficking and diabetes development.
Journal: BMC immunology 20080101
Title: Discovery of small molecule CXCR4 antagonists.
Journal: Journal of medicinal chemistry 20071115
Title: Effects of AMD3100 on transmigration and survival of acute myelogenous leukemia cells.
Journal: Leukemia research 20071101
Title: Mobilization of peripheral blood stem cells.
Journal: Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20071001
Title: Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor.
Journal: The Journal of biological chemistry 20070914
Title: Stromal cell-derived factor-1 induces matrix metalloprotease-13 expression in human chondrocytes.
Journal: Molecular pharmacology 20070901
Title: Migration of endothelial progenitor cells mediated by stromal cell-derived factor-1alpha/CXCR4 via PI3K/Akt/eNOS signal transduction pathway.
Journal: Journal of cardiovascular pharmacology 20070901
Title: HIV entry inhibitors.
Journal: Lancet (London, England) 20070707
Title: CXCR4 chemokine receptor signaling mediates pain hypersensitivity in association with antiretroviral toxic neuropathy.
Journal: Brain, behavior, and immunity 20070701
Title: Multiple-dose escalation study of the safety, pharmacokinetics, and biologic activity of oral AMD070, a selective CXCR4 receptor inhibitor, in human subjects.
Journal: Antimicrobial agents and chemotherapy 20070701
Title: Modification of post-myocardial infarction granulocyte-colony stimulating factor therapy with myelo-suppressives.
Journal: Circulation journal : official journal of the Japanese Circulation Society 20070401
Title: Roles of the MEK1/2 and AKT pathways in CXCL12/CXCR4 induced cholangiocarcinoma cell invasion.
Journal: World journal of gastroenterology 20070314
Title: Isolation and characterization of human immunodeficiency virus type 1 resistant to the small-molecule CCR5 antagonist TAK-652.
Journal: Antimicrobial agents and chemotherapy 20070201
Title: Pradimicin A, a carbohydrate-binding nonpeptidic lead compound for treatment of infections with viruses with highly glycosylated envelopes, such as human immunodeficiency virus.
Journal: Journal of virology 20070101
Title: Carbohydrate-binding agents efficiently prevent dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin (DC-SIGN)-directed HIV-1 transmission to T lymphocytes.
Journal: Molecular pharmacology 20070101
Title: Plerixafor: AMD 3100, AMD3100, JM 3100, SDZ SID 791.
Journal: Drugs in R&D 20070101
Title: Mobilization of bone marrow-derived progenitors.
Journal: Handbook of experimental pharmacology 20070101
Title: Small molecule CXCR4 chemokine receptor antagonists: developing drug candidates.
Journal: Current medicinal chemistry 20070101
Title: Synthesis and anti-HIV properties of new hydroxyquinoline-polyamine conjugates on cells infected by HIV-1 LAV and HIV-1 BaL viral strains.
Journal: Bioorganic & medicinal chemistry letters 20061201
Title: CXCR4 inhibition synergizes with cytotoxic chemotherapy in gliomas.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20061115
Title: Configurationally restricted bismacrocyclic CXCR4 receptor antagonists.
Journal: Journal of medicinal chemistry 20061019
Title: Meninges control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling.
Journal: Nature neuroscience 20061001
Title: HIV co-receptor inhibitors as novel class of anti-HIV drugs.
Journal: Antiviral research 20060901
Title: Characterization of the molecular pharmacology of AMD3100: a specific antagonist of the G-protein coupled chemokine receptor, CXCR4.
Journal: Biochemical pharmacology 20060828
Title: Axonal transport of human immunodeficiency virus type 1 envelope protein glycoprotein 120 is found in association with neuronal apoptosis.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060621
Title: 1,1'-Xylyl bis-1,4,8,11-tetraaza cyclotetradecane: a new potential copper chelator agent for neuroprotection in Alzheimer's disease. Its comparative effects with clioquinol on rat brain copper distribution.
Journal: Bioorganic & medicinal chemistry letters 20060615
Title: AMD3100 mobilizes hematopoietic stem cells with long-term repopulating capacity in nonhuman primates.
Journal: Blood 20060501
Title: Stromal cell-derived factor-1alpha modulation of the excitability of rat substantia nigra dopaminergic neurones: presynaptic mechanisms.
Journal: Journal of neurochemistry 20060301
Title: The temperature arrested intermediate of virus-cell fusion is a functional step in HIV infection.
Journal: Virology journal 20060101
Title: The Role of Plerixafor (AMD3100) in Mobilizing Hematopoietic Progenitor Cells in Patients with Hematologic Malignancies.
Journal: Supportive cancer therapy 20060101
Title: The development of an europium-GTP assay to quantitate chemokine antagonist interactions for CXCR4 and CCR5.
Journal: Assay and drug development technologies 20051201
Title: TAK-652 inhibits CCR5-mediated human immunodeficiency virus type 1 infection in vitro and has favorable pharmacokinetics in humans.
Journal: Antimicrobial agents and chemotherapy 20051101
Title: A CXCR4-dependent chemorepellent signal contributes to the emigration of mature single-positive CD4 cells from the fetal thymus.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20051015
Title: Evaluation of the anti-HIV activity of statins.
Journal: AIDS (London, England) 20051014
Title: Regulation of neuronal P53 activity by CXCR 4.
Journal: Molecular and cellular neurosciences 20050901
Title: AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor.
Journal: Biochemical pharmacology 20050901
Title: Potential clinical applications of the CXCR4 antagonist bicyclam AMD3100.
Journal: Mini reviews in medicinal chemistry 20050901
Title: Highly potent inhibition of human immunodeficiency virus type 1 replication by TAK-220, an orally bioavailable small-molecule CCR5 antagonist.
Journal: Antimicrobial agents and chemotherapy 20050801
Title: Theaflavin derivatives in black tea and catechin derivatives in green tea inhibit HIV-1 entry by targeting gp41.
Journal: Biochimica et biophysica acta 20050525
Title: Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis.
Journal: Molecular pharmacology 20050501
Title: Stromal cell-derived factor-1alpha directly modulates voltage-dependent currents of the action potential in mammalian neuronal cells.
Journal: Journal of neurochemistry 20050501
Title: Discovery of small-molecule human immunodeficiency virus type 1 entry inhibitors that target the gp120-binding domain of CD4.
Journal: Journal of virology 20050501
Title: The chemokine stromal cell-derived factor-1 regulates the migration of sensory neuron progenitors.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050420
Title: Innovative strategies for PBPC mobilization.
Journal: Cytotherapy 20050101
Title: Pro-inflammatory properties of stromal cell-derived factor-1 (CXCL12) in collagen-induced arthritis.
Journal: Arthritis research & therapy 20050101
Title: Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist.
Journal: Journal of virology 20041201
Title: CADA, a novel CD4-targeted HIV inhibitor, is synergistic with various anti-HIV drugs in vitro.
Journal: AIDS (London, England) 20041105
Title: Profile of resistance of human immunodeficiency virus to mannose-specific plant lectins.
Journal: Journal of virology 20041001
Title: Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection.
Journal: Antimicrobial agents and chemotherapy 20041001
Title: Cyclam complexes and their applications in medicine.
Journal: Chemical Society reviews 20040510
Title: Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue.
Journal: The Journal of experimental medicine 20040419
Title: Mechanism of feline immunodeficiency virus envelope glycoprotein-mediated fusion.
Journal: Virology 20040410
Title: Molecular mechanism of AMD3100 antagonism in the CXCR4 receptor: transfer of binding site to the CXCR3 receptor.
Journal: The Journal of biological chemistry 20040123
Title: New bicyclam-GalCer analogue conjugates: synthesis and in vitro anti-HIV activity.
Journal: Bioorganic & medicinal chemistry letters 20040119
Title: The chemokine receptor CXCR4 and not the N-methyl-D-aspartate receptor mediates gp120 neurotoxicity in cerebellar granule cells.
Journal: Journal of neuroscience research 20040101
Title: AMD3100 conjugates as components of targeted nonviral gene delivery systems: synthesis and in vitro transfection efficiency of CXCR4-expressing cells.
Journal: Bioconjugate chemistry 20040101
Title: Establishment of a novel CCR5 and CXCR4 expressing CD4+ cell line which is highly sensitive to HIV and suitable for high-throughput evaluation of CCR5 and CXCR4 antagonists.
Journal: Retrovirology 20040101
Title: Resistance to HIV-1 entry inhibitors.
Journal: Current drug targets. Infectious disorders 20031201
Title: Lipid bilayer simulations of CXCR4 with inverse agonists and weak partial agonists.
Journal: The Journal of biological chemistry 20031121
Title: Potent and selective inhibition of HIV and SIV by prostratin interacting with viral entry.
Journal: Antiviral chemistry & chemotherapy 20031101
Title: Direct synthesis of 1,1'-[1,4-phenylenebis(methylene)]-bis- 1,4,8,11-tetraazacyclotetradecane octahydrochloride (AMD 3100) without the use of protecting groups.
Journal: The Journal of organic chemistry 20030808
Title: Mutations at the CXCR4 interaction sites for AMD3100 influence anti-CXCR4 antibody binding and HIV-1 entry.
Journal: FEBS letters 20030710
Title: Brain-derived neurotrophic factor inhibits human immunodeficiency virus-1/gp120-mediated cerebellar granule cell death by preventing gp120 internalization.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030702
Title: Broad spectrum anti-RNA virus activities of titanium and vanadium substituted polyoxotungstates.
Journal: Antiviral research 20030501
Title: The CCR5 and CXCR4 coreceptors are both used by human immunodeficiency virus type 1 primary isolates from subtype C.
Journal: Journal of virology 20030401
Title: A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20030401
Title: Establishment of an in vitro assay system mimicking human immunodeficiency virus type 1-induced neural cell death and evaluation of inhibitors thereof.
Journal: Journal of virological methods 20030301
Title: Metal ion enhanced binding of AMD3100 to Asp262 in the CXCR4 receptor.
Journal: Biochemistry 20030128
Title: Evaluation of SDF-1/CXCR4-induced Ca2+ signaling by fluorometric imaging plate reader (FLIPR) and flow cytometry.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030101
Title: Multiple actions of the chemokine CXCL12 on epithelial tumor cells in human ovarian cancer.
Journal: Cancer research 20021015
Title: Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives.
Journal: Antimicrobial agents and chemotherapy 20021001
Title: Chemokine receptor inhibition by AMD3100 is strictly confined to CXCR4.
Journal: FEBS letters 20020911
Title: Structure and dynamics of metallomacrocycles: recognition of zinc xylyl-bicyclam by an HIV coreceptor.
Journal: Journal of the American Chemical Society 20020807
Title: A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists.
Journal: The Journal of biological chemistry 20020705
Title: Non-peptidic chemokine receptors antagonists as emerging anti-HIV agents.
Journal: Journal of enzyme inhibition and medicinal chemistry 20020401
Title: Anti-HIV activity of a novel aminoglycoside-arginine conjugate.
Journal: Antiviral research 20020101
Title: AMD3100, a potent and specific antagonist of the stromal cell-derived factor-1 chemokine receptor CXCR4, inhibits autoimmune joint inflammation in IFN-gamma receptor-deficient mice.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20011015
Title: Hamao Umezawa Memorial Award Lecture: 'An Odyssey in the Viral Chemotherapy Field'.
Journal: International journal of antimicrobial agents 20011001
Title: Novel low molecular weight spirodiketopiperazine derivatives potently inhibit R5 HIV-1 infection through their antagonistic effects on CCR5.
Journal: The Journal of biological chemistry 20010914
Title: Pharmacological evidence for complex and multiple site interaction of CXCR4 with SDF-1alpha: implications for development of selective CXCR4 antagonists.
Journal: Immunology letters 20010801
Title: Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.
Journal: Molecular pharmacology 20010701
Title: HIV fusion and its inhibition.
Journal: Antiviral research 20010501
Title: Biological and genetic characterization of a human immunodeficiency virus strain resistant to CXCR4 antagonist T134.
Journal: AIDS research and human retroviruses 20010501
Title: Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor.
Journal: The Journal of biological chemistry 20010427
Title: Increase of R5 HIV-1 infection and CCR5 expression in T cells treated with high concentrations of CXCR4 antagonists and SDF-1.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20010301
Title: Inhibition of HIV infection by CXCR4 and CCR5 chemokine receptor antagonists.
Journal: Antiviral chemistry & chemotherapy 20010101
Title: Strong in vitro synergy between the fusion inhibitor T-20 and the CXCR4 blocker AMD-3100.
Journal: Journal of acquired immune deficiency syndromes (1999) 20001001
Title: Viral entry as the primary target for the anti-HIV activity of chicoric acid and its tetra-acetyl esters.
Journal: Molecular pharmacology 20000901
Title: Inhibition of HIV infection by bicyclams, highly potent and specific CXCR4 antagonists.
Journal: Molecular pharmacology 20000501
Title: Anti-human immunodeficiency virus activity of novel aminoglycoside-arginine conjugates at early stages of infection.
Journal: AIDS research and human retroviruses 20000501
Title: Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease.
Journal: Journal of virology 20000101
Title: The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface-expressed human immunodeficiency virus type 1 envelope-induced apoptosis.
Journal: Antimicrobial agents and chemotherapy 20000101
Title: Resistance of the human immunodeficiency virus to the inhibitory action of negatively charged albumins on virus binding to CD4.
Journal: AIDS research and human retroviruses 19991120
Title: Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-azamacrocycles that inhibit HIV-1 and HIV-2 replication by antagonism of the chemokine receptor CXCR4.
Journal: Journal of medicinal chemistry 19990923
Title: A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19990511
Title: Marked increase in anti-HIV activity, as well as inhibitory activity against HIV entry mediated by CXCR4, linked to enhancement of the binding ability of tachyplesin analogs to CXCR4.
Journal: AIDS research and human retroviruses 19990320
Title: T134, a small-molecule CXCR4 inhibitor, has no cross-drug resistance with AMD3100, a CXCR4 antagonist with a different structure.
Journal: Journal of virology 19990201
Title: New bicyclam-AZT conjugates: design, synthesis, anti-HIV evaluation, and their interaction with CXCR-4 coreceptor.
Journal: Journal of medicinal chemistry 19990128
Title: Activity of different bicyclam derivatives against human immunodeficiency virus depends on their interaction with the CXCR4 chemokine receptor.
Journal: Molecular pharmacology 19990101
Title: A low-molecular-weight inhibitor against the chemokine receptor CXCR4: a strong anti-HIV peptide T140.
Journal: Biochemical and biophysical research communications 19981230
Title: T-cell-line-tropic human immunodeficiency virus type 1 that is made resistant to stromal cell-derived factor 1alpha contains mutations in the envelope gp120 but does not show a switch in coreceptor use.
Journal: Journal of virology 19980501
Title: Human immunodeficiency virus glycoprotein gp120 as the primary target for the antiviral action of AR177 (Zintevir).
Journal: Molecular pharmacology 19980201
Title: AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor.
Journal: Nature medicine 19980101
Title: Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4.
Journal: The Journal of experimental medicine 19971020
Title: Bicyclams, a class of potent anti-HIV agents, are targeted at the HIV coreceptor fusin/CXCR-4.
Journal: Antiviral research 19970801
Title: Development of resistance of human immunodeficiency virus type 1 to dextran sulfate associated with the emergence of specific mutations in the envelope gp120 glycoprotein.
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