Name: Name:CH-55
Brand: AABLOCKS
SKU: AA008SD8
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA008SD8

Chemical Name: CH-55

CAS Number: 110368-33-7

Molecular Formula: C24H28O3

Molecular Weight: 364.4773

MDL Number: MFCD06798383

SMILES: O=C(c1cc(cc(c1)C(C)(C)C)C(C)(C)C)/C=C/c1ccc(cc1)C(=O)O

NSC Number: 608002

Properties

Complexity: 531

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 1

Formal Charge: 0

Heavy Atom Count: 27

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 6

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 6.6

Literature fold

Title: 9-cis-Retinoic acid (9cRA), a retinoid X receptor (RXR) ligand, exerts immunosuppressive effects on dendritic cells by RXR-dependent activation: inhibition of peroxisome proliferator-activated receptor gamma blocks some of the 9cRA activities, and precludes them to mature phenotype development.

Journal: Journal of immunology (Baltimore, Md. : 1950)20070515

Title: Differential expression of heparin-binding EGF-like growth factor (HB-EGF) mRNA in normal human keratinocytes induced by a variety of natural and synthetic retinoids.

Journal: Experimental dermatology20030101

Title: [The role of exogenous hRAR beta gene on the growth inhibition and differentiation induction of HL-60R Cells].

Journal: Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi20011001

Title: Involvement of retinoic acid receptor alpha in the stimulation of tissue-type plasminogen-activator gene expression in human endothelial cells.

Journal: European journal of biochemistry19950901

Title: The prevention of adipose differentiation of 3T3-L1 cells caused by retinoic acid is elicited through retinoic acid receptor alpha.

Journal: Life sciences19940101

Title: New benzoic acid derivatives with retinoid activity: lack of direct correlation between biological activity and binding to cellular retinoic acid binding protein.

Journal: Cancer research19870701

Title: Jetten AM, et al. New benzoic acid derivatives with retinoid activity: lack of direct correlation between biological activity and binding to cellular retinoic acid binding protein. Cancer Res. 1987 Jul 1;47(13):3523-7.

Title: Takahashi N, et al. Induction of differentiation and covalent binding to proteins by the synthetic retinoids Ch55 and Am80. Arch Biochem Biophys. 1994 Oct;314(1):82-9.

110368-33-7 | CH-55