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11042-64-1,MFCD00867548
Catalog No.:AA003QNT

11042-64-1 | Gamma-Oryzanol

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1g
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$24.00   $17.00
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25g
95
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250g
95
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003QNT
Chemical Name:
Gamma-Oryzanol
CAS Number:
11042-64-1
Molecular Formula:
C40H58O4
Molecular Weight:
602.8861
MDL Number:
MFCD00867548
SMILES:
COc1cc(C=CC(=O)OC2CCC34C(C2(C)C)CCC2C4(C3)CCC3(C2(C)CCC3C(CCC=C(C)C)C)C)ccc1O
Properties
Properties
 
BP:
663.2°C at 760 mmHg  
Form:
Solid  
MP:
135-137°C  
Refractive Index:
1.4760 (estimate)  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
1150  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
44  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
9  
XLogP3:
12.1  

Literature

Title: Cycloartenyl Ferulate Inhibits Paraquat-Induced Apoptosis in HK-2 Cells With the Involvement of ABCC1.

Journal: Journal of cellular biochemistry 20160401

Title: γ-Oryzanol protects against acute cadmium-induced oxidative damage in mice testes.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130501

Title: Upregulation of genes related to bone formation by γ-amino butyric acid and γ-oryzanol in germinated brown rice is via the activation of GABAB-receptors and reduction of serum IL-6 in rats.

Journal: Clinical interventions in aging 20130101

Title: Effect of gamma-oryzanol-enriched rice bran oil on quality of cryopreserved boar semen.

Journal: The Journal of veterinary medical science 20120901

Title: Dietary rice bran component γ-oryzanol inhibits tumor growth in tumor-bearing mice.

Journal: Molecular nutrition & food research 20120601

Title: γ-Oryzanol, tocol and mineral compositions in different grain fractions of giant embryo rice mutants.

Journal: Journal of the science of food and agriculture 20120501

Title: γ-Oryzanol reduces adhesion molecule expression in vascular endothelial cells via suppression of nuclear factor-κB activation.

Journal: Journal of agricultural and food chemistry 20120404

Title: Effect of gamma-oryzanol on the bioaccessibility and synthesis of cholesterol.

Journal: European review for medical and pharmacological sciences 20120101

Title: Effect of saponification on composition of unsaponifiable matter in rice bran oil.

Journal: Journal of oleo science 20120101

Title: Characterization of high-value bioactives in some selected varieties of Pakistani Rice (Oryza sativa L.).

Journal: International journal of molecular sciences 20120101

Title: Improvement of leucocyte functions in mature and old mice after 15 and 30 weeks of diet supplementation with polyphenol-rich biscuits.

Journal: European journal of nutrition 20111001

Title: Anti-inflammatory principles from Cordyceps sinensis.

Journal: Journal of natural products 20110923

Title: γ-Oryzanol recovers mouse hypoadiponectinemia induced by animal fat ingestion.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110615

Title: Oral administration of γ-aminobutyric acid and γ-oryzanol prevents stress-induced hypoadiponectinemia.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20110615

Title: Phytochemicals characterization of solvent extracts from taro-scented japonica rice bran.

Journal: Journal of food science 20110501

Title: BJSM reviews: A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--Part 16.

Journal: British journal of sports medicine 20110101

Title: Phytochemicals and antioxidant capacities in rice brans of different color.

Journal: Journal of food science 20110101

Title: Effect of oryzanol and ferulic acid on the glucose metabolism of mice fed with a high-fat diet.

Journal: Journal of food science 20110101

Title: [Clinical stabilisation in neurodegenerative diseases: clinical study in phase II].

Journal: Revista de neurologia 20100501

Title: Chemical and structural investigation of lipid nanoparticles: drug-lipid interaction and molecular distribution.

Journal: Nanotechnology 20100326

Title: Cycloartenyl ferulate, a component of rice bran oil-derived gamma-oryzanol, attenuates mast cell degranulation.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20100201

Title: Effect of pre-germination time of brown rice on serum cholesterol levels of hypercholesterolaemic rats.

Journal: Journal of the science of food and agriculture 20100130

Title: Gamma-oryzanol ameliorates insulin resistance and hyperlipidemia in rats with streptozotocin/nicotinamide-induced type 2 diabetes.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20100101

Title: Antioxidant, free radical-scavenging, and NF-kappaB-inhibitory activities of phytosteryl ferulates: structure-activity studies.

Journal: Journal of pharmacological sciences 20091201

Title: Novel 3alpha-methoxyserrat-14-en-21beta-ol (PJ-1) and 3beta-methoxyserrat-14-en-21beta-ol (PJ-2)-curcumin, kojic acid, quercetin, and baicalein conjugates as HIV agents.

Journal: Bioorganic & medicinal chemistry 20090715

Title: The effects of hydroxycinnamic acid derivatives on adiponectin secretion.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20090301

Title: Lipophilic and hydrophilic antioxidants and their antioxidant activities in purple rice bran.

Journal: Journal of agricultural and food chemistry 20090211

Title: Isolation of oryzanol from crude rice bran oil.

Journal: Bioresource technology 20090101

Title: Degradation kinetics of gamma-oryzanol in antioxidant-stripped rice bran oil during thermal oxidation.

Journal: Journal of oleo science 20090101

Title: Comparison of gamma-oryzanol contents in crude rice bran oils from different sources by various determination methods.

Journal: Journal of oleo science 20090101

Title: Physicochemical properties and antioxidant activity of gamma-oryzanol-loaded liposome formulations for topical use.

Journal: Pharmaceutical development and technology 20090101

Title: Enriching oryzanol in rice bran oil using membranes.

Journal: Applied biochemistry and biotechnology 20081201

Title: The effect of trans-ferulic acid and gamma-oryzanol on ethanol-induced liver injury in C57BL mouse.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20081101

Title: Lipase catalyzed interesterification of palm stearin and rice bran oil blends for preparation of zero trans shortening with bioactive phytochemicals.

Journal: Bioresource technology 20080701

Title: Anti-inflammatory effects of phytosteryl ferulates in colitis induced by dextran sulphate sodium in mice.

Journal: British journal of pharmacology 20080601

Title: Effects of dietary supplementation of ferulic acid and gamma-oryzanol on integument color and suppression of oxidative stress in cultured red sea bream, Pagrus major.

Journal: Journal of oleo science 20080101

Title: Pharmacological interventions for clozapine-induced hypersalivation.

Journal: The Cochrane database of systematic reviews 20080101

Title: Phytochemical characterization of defatted rice bran and optimization of a process for their extraction and enrichment.

Journal: Bioresource technology 20071101

Title: Antiradical efficacy of phytochemical extracts from defatted rice bran.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071001

Title: Quantification of vitamin E and gamma-oryzanol components in rice germ and bran.

Journal: Journal of agricultural and food chemistry 20070905

Title: Influence of growth temperature on the amounts of tocopherols, tocotrienols, and gamma-oryzanol in brown rice.

Journal: Journal of agricultural and food chemistry 20070905

Title: Cancer chemopreventive effects of cycloartane-type and related triterpenoids in in vitro and in vivo models.

Journal: Journal of natural products 20070601

Title: Rice bran oil and oryzanol reduce plasma lipid and lipoprotein cholesterol concentrations and aortic cholesterol ester accumulation to a greater extent than ferulic acid in hypercholesterolemic hamsters.

Journal: The Journal of nutritional biochemistry 20070201

Title: Content of gamma-oryzanol and composition of steryl ferulates in brown rice (Oryza sativa L.) of European origin.

Journal: Journal of agricultural and food chemistry 20061018

Title: Effects of combined dietary supplementation on oxidative and inflammatory status in dyslipidemic subjects.

Journal: Nutrition, metabolism, and cardiovascular diseases : NMCD 20060301

Title: Antioxidative activity of microencapsulated gamma-oryzanol on high cholesterol-fed rats.

Journal: Journal of agricultural and food chemistry 20051214

Title: Increased immune response in mice consuming rice bran oil.

Journal: European journal of nutrition 20051201

Title: Simultaneous determination of carotenoids, tocopherols, and gamma-oryzanol in crude rice bran oil by liquid chromatography coupled to diode array and mass spectrometric detection employing silica C30 stationary phases.

Journal: Journal of separation science 20050901

Title: Antioxidant activity of gamma-oryzanol: mechanism of action and its effect on oxidative stability of pharmaceutical oils.

Journal: International journal of pharmaceutics 20050811

Title: Antioxidant activity of steryl ferulate extracts from rye and wheat bran.

Journal: Journal of agricultural and food chemistry 20050406

Title: Similar cholesterol-lowering properties of rice bran oil, with varied gamma-oryzanol, in mildly hypercholesterolemic men.

Journal: European journal of nutrition 20050301

Title: Prevention of brain protein and lipid oxidation elicited by a water-soluble oryzanol enzymatic extract derived from rice bran.

Journal: European journal of nutrition 20031201

Title: Characterization of triterpene alcohol and sterol ferulates in rice bran using LC-MS/MS.

Journal: Journal of agricultural and food chemistry 20030521

Title: Comparison of three spectrophotometric methods for the determination of gamma-oryzanol in rice bran oil.

Journal: Analytical and bioanalytical chemistry 20030401

Title: Coupled liquid chromatography-gas chromatography for the rapid analysis of gamma-oryzanol in rice lipids.

Journal: Journal of chromatography. A 20030124

Title: Rice bran oil and gamma-oryzanol in the treatment of hyperlipoproteinaemias and other conditions.

Journal: Phytotherapy research : PTR 20010601

Title: Antioxidant activity of tocopherols, tocotrienols, and gamma-oryzanol components from rice bran against cholesterol oxidation accelerated by 2,2'-azobis(2-methylpropionamidine) dihydrochloride.

Journal: Journal of agricultural and food chemistry 20010401

Title: Screening of chemiluminescence constituents of cereals and DPPH radical scavenging activity of gamma-oryzanol.

Journal: Luminescence : the journal of biological and chemical luminescence 20010101

Title: Modifying effects of the naturally occurring antioxidants gamma-oryzanol, phytic acid, tannic acid and n-tritriacontane-16, 18-dione in a rat wide-spectrum organ carcinogenesis model.

Journal: Carcinogenesis 19911001

Title: Lack of modification by naturally occurring antioxidants of 3,2'-dimethyl-4-aminobiphenyl-initiated rat prostate carcinogenesis.

Journal: Cancer letters 19910704

Title: Kozuka C, et al. Impact of brown rice-specific γ-oryzanol on epigenetic modulation of dopamine D2 receptors in brain striatum in high-fat-diet-induced obesity in mice. Diabetologia. 2017 Aug;60(8):1502-1511.

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