Catalog No.:AA008X4O

1106685-66-8 | (S)-4-HydroxyMethyl AMbrisentan

Name: Name:(S)-4-HydroxyMethyl AMbrisentan
Brand: AABLOCKS
SKU: AA008X4O
Rating: 90 (10 reviews)

This product is typically in stock,please click "Inquire" below or
contact us at [email protected] for pricing and availability information.

Technical Information
Properties
Literature
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Technical Information

Catalog Number:

AA008X4O

Chemical Name:

(S)-4-HydroxyMethyl AMbrisentan

CAS Number:

1106685-66-8

Molecular Formula:

C22H22N2O5

Molecular Weight:

394.4205

SMILES:

CC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)CO

Properties

Computed Properties

Complexity:

501

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Rotatable Bond Count:

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

2.6

Literature

Title: Effects of rifampicin (rifampin) on the pharmacokinetics and safety of ambrisentan in healthy subjects: a single-sequence, open-label study.

Journal: Clinical drug investigation 20100101

Title: No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers.

Journal: Journal of pharmaceutical sciences 20091201

Title: Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.

Journal: Journal of clinical pharmacology 20090601

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SDS

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Tags:1106685-66-8 Molecular Formula|1106685-66-8 MDL|1106685-66-8 SMILES|1106685-66-8 (S)-4-HydroxyMethyl AMbrisentan

Catalog No.: AA008X4O

1106685-66-8 | (S)-4-HydroxyMethyl AMbrisentan

This product is typically in stock,please click "Inquire" below or contact us at [email protected]for pricing and availability information.

Inquire

Technical Information

Catalog Number: AA008X4O

Chemical Name: (S)-4-HydroxyMethyl AMbrisentan

CAS Number: 1106685-66-8

Molecular Formula: C22H22N2O5

Molecular Weight: 394.4205

SMILES: CC1=CC(=NC(=N1)OC(C(=O)O)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC)CO

Properties

Complexity: 501

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 29

Hydrogen Bond Acceptor Count: 7

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 8

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 2.6

Literature fold

Title: Effects of rifampicin (rifampin) on the pharmacokinetics and safety of ambrisentan in healthy subjects: a single-sequence, open-label study.

Journal: Clinical drug investigation20100101

Title: No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers.

Journal: Journal of pharmaceutical sciences20091201

Title: Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.

Journal: Journal of clinical pharmacology20090601

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AA008XHF | MFCD27966164

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AA008XTD | MFCD15143360

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(R)-1-(2,6-Dichlorophenyl)ethanamine hydrochloride

AA008Y4Q | MFCD12757835

1043688-99-8

2-Bromo-5-methoxypyridin-3-amine

AA008YYC | MFCD16659663

10378-23-1

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate

AA008Z3V | MFCD00012460

1051919-32-4

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AA008ZQM | MFCD08559399

1049036-18-1

2',5'-Dichlorobiphenyl-3-carboxylic acid

AA0090CV | MFCD11574811

1185300-18-8

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AA0090OK | MFCD11100556

1170404-43-9

2-[(4-Fluorobenzyl)sulfanyl]ethylamine, HCl

AA0090VE | MFCD09027133

103854-26-8

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AA009137 | MFCD09842594

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