[1]CurrentPatentAssignee:GILEADSCIENCESINC-WO2009/17777,2009,A2Locationinpatent:Page/Pagecolumn24-25
[1]Patent:JP2017/128528,2017,A.Locationinpatent:Paragraph0005;0047
[2]Patent:KR2016/39907,2016,A.Locationinpatent:Paragraph0113;0114;0116;0117
[3]Patent:WO2010/70658,2010,A2.Locationinpatent:Page/Pagecolumn24
[4]Patent:WO2011/114338,2011,A1.Locationinpatent:Page/Pagecolumn8-9
[5]Patent:US2011/263854,2011,A1.Locationinpatent:Page/Pagecolumn10
[6]Patent:EP2476670,2012,A1.Locationinpatent:Page/Pagecolumn4
[7]Patent:US2013/60031,2013,A1.Locationinpatent:Paragraph0057;0058;0059
[1]CurrentPatentAssignee:CIPLALTD-WO2013/57468,2013,A1Locationinpatent:Page/Pagecolumn22
[2]CurrentPatentAssignee:MSNLABORATORIESPRIVATELIMITED-WO2010/70658,2010,A2Locationinpatent:Page/Pagecolumn22
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[1]Patent:US2012/184573,2012,A1.Locationinpatent:Page/Pagecolumn11
[2]Patent:WO2011/4402,2011,A2.Locationinpatent:Page/Pagecolumn24
Title: Endothelin-1 receptor antagonists in fetal development and pulmonary arterial hypertension.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20150815
Title: Ambrisentan for the treatment of adults with pulmonary arterial hypertension: a review.
Journal: Current medical research and opinion 20150101
Title: AMBITION: An important piece in the therapeutic puzzle of pulmonary arterial hypertension.
Journal: Global cardiology science & practice 20150101
Title: Lack of a clinically significant interaction of grapefruit juice with ambrisentan and bosentan in healthy adults.
Journal: International journal of clinical pharmacology and therapeutics 20141101
Title: Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1.
Journal: European journal of clinical pharmacology 20131001
Title: Clinical pharmacokinetics and drug-drug interactions of endothelin receptor antagonists in pulmonary arterial hypertension.
Journal: Journal of clinical pharmacology 20121201
Title: Frequency of edema in patients with pulmonary arterial hypertension receiving ambrisentan.
Journal: The American journal of cardiology 20121101
Title: Safety and efficacy evaluation of ambrisentan in pulmonary hypertension.
Journal: Expert opinion on drug safety 20121101
Title: Comparison of human ETA and ETB receptor signalling via G-protein and β-arrestin pathways.
Journal: Life sciences 20121015
Title: Defining the affinity and receptor sub-type selectivity of four classes of endothelin antagonists in clinically relevant human cardiovascular tissues.
Journal: Life sciences 20121015
Title: Endothelin receptor antagonists for the treatment of pulmonary artery hypertension.
Journal: Life sciences 20121015
Title: The combination of theophylline and endothelin receptor antagonism improves exercise performance of rats under simulated high altitude.
Journal: Journal of applied physiology (Bethesda, Md. : 1985) 20121015
Title: LC-ESI-MS/MS method for quantification of ambrisentan in plasma and application to rat pharmacokinetic study.
Journal: Biomedical chromatography : BMC 20121001
Title: Long-term hepatic safety of ambrisentan in patients with pulmonary arterial hypertension.
Journal: Journal of the American College of Cardiology 20120703
Title: Long-term safety and efficacy of ambrisentan in Japanese adults with pulmonary arterial hypertension.
Journal: Current medical research and opinion 20120601
Title: Treatment of pulmonary arterial hypertension in connective tissue disease.
Journal: Drugs 20120528
Title: Risk evaluation and mitigation strategies: assessment of a medical center's policies and procedures.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120515
Title: Chronic endothelin A receptor blockade attenuates contribution of sympathetic nervous system to salt hypertension development in adult but not in young Dahl rats.
Journal: Acta physiologica (Oxford, England) 20120501
Title: Ambrisentan for pulmonary arterial hypertension: long term effects on clinical status, exercise capacity and haemodynamics.
Journal: International journal of cardiology 20120419
Title: Endothelin-1 promotes cytoplasmic accumulation of RIP140 through a ET(A)-PLCβ-PKCε pathway.
Journal: Molecular and cellular endocrinology 20120404
Title: ARIES-3: ambrisentan therapy in a diverse population of patients with pulmonary hypertension.
Journal: Cardiovascular therapeutics 20120401
Title: eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype.
Journal: Journal of the American Society of Nephrology : JASN 20120401
Title: Rapid determination of ambrisentan enantiomers by enantioselective liquid chromatography using cellulose-based chiral stationary phase in reverse phase mode.
Journal: Journal of separation science 20120401
Title: Effect of cyclosporine and rifampin on the pharmacokinetics of macitentan, a tissue-targeting dual endothelin receptor antagonist.
Journal: The AAPS journal 20120301
Title: Ambrisentan and tadalafil synergistically relax endothelin-induced contraction of rat pulmonary arteries.
Journal: Hypertension (Dallas, Tex. : 1979) 20120301
Title: Synthesis of (+)-ambrisentan via chiral ketone-catalyzed asymmetric epoxidation.
Journal: The Journal of organic chemistry 20120106
Title: Race and sex differences in response to endothelin receptor antagonists for pulmonary arterial hypertension.
Journal: Chest 20120101
Title: Inhaled treprostinil: a therapeutic review.
Journal: Drug design, development and therapy 20120101
Title: Pulmonary arterial hypertension: advances in pathophysiology and management.
Journal: Indian journal of pharmacology 20120101
Title: A novel expression of exercise induced pulmonary hypertension in human immunodeficiency virus patients: a pilot study.
Journal: The open cardiovascular medicine journal 20120101
Title: Treatment patterns and healthcare system burden of managed care patients with suspected pulmonary arterial hypertension in the United States.
Journal: Journal of medical economics 20120101
Title: Smooth muscle myosin inhibition: a novel therapeutic approach for pulmonary hypertension.
Journal: PloS one 20120101
Title: Slow receptor dissociation kinetics differentiate macitentan from other endothelin receptor antagonists in pulmonary arterial smooth muscle cells.
Journal: PloS one 20120101
Title: Pulmonary arterial hypertension: an update.
Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20111201
Title: [Treatment of pulmonary fibrosis. New substances and new interventions].
Journal: Der Internist 20111201
Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Journal: PLoS computational biology 20111201
Title: Adult congenital heart disease and pulmonary arterial hypertension: the Texas Adult Congenital Heart Program experience.
Journal: Postgraduate medicine 20111101
Title: Macitentan: entry-into-humans study with a new endothelin receptor antagonist.
Journal: European journal of clinical pharmacology 20111001
Title: Endothelin receptor antagonists -- their role in pulmonary medicine.
Journal: Revue des maladies respiratoires 20111001
Title: Ambrisentan for sarcoidosis associated pulmonary hypertension.
Journal: Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20111001
Title: Efficacy, safety, and pharmacokinetics of ambrisentan in Japanese adults with pulmonary arterial hypertension.
Journal: Current medical research and opinion 20110901
Title: Ambrisentan improves exercise capacity and symptoms in patients with portopulmonary hypertension.
Journal: Zeitschrift fur Gastroenterologie 20110901
Title: Bosentan and oral anticoagulants in HIV patients: what we can learn of cases reported so far.
Journal: Hematology reports 20110831
Title: Ambrisentan.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20110801
Title: Long-term pulmonary hemodynamic effects of ambrisentan in pulmonary arterial hypertension.
Journal: The American journal of cardiology 20110715
Title: Endothelin receptor antagonists for the treatment of pulmonary arterial hypertension.
Journal: Expert opinion on pharmacotherapy 20110701
Title: Synthesis and in vitro evaluation of ambrisentan analogues as potential endothelin receptor antagonists.
Journal: Bioorganic & medicinal chemistry letters 20110701
Title: [Treatment of idiopathic pulmonary arterial hypertension].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20110701
Title: Differential modulation of the expression of important drug metabolising enzymes and transporters by endothelin-1 receptor antagonists ambrisentan and bosentan in vitro.
Journal: European journal of pharmacology 20110625
Title: New perspectives for the treatment of pulmonary hypertension.
Journal: British journal of pharmacology 20110501
Title: Novel therapeutic approaches for pulmonary fibrosis.
Journal: British journal of pharmacology 20110501
Title: Ambrisentan for pulmonary arterial hypertension due to congenital heart disease.
Journal: The American journal of cardiology 20110501
Title: With REMS, what goes up can come down.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110501
Title: Treprostinil increases the number and angiogenic potential of endothelial progenitor cells in children with pulmonary hypertension.
Journal: Angiogenesis 20110301
Title: Survival after the initiation of combination therapy in patients with pulmonary arterial hypertension: an Australian collaborative report.
Journal: Internal medicine journal 20110301
Title: Pharmacokinetic evaluation of ambrisentan.
Journal: Expert opinion on drug metabolism & toxicology 20110301
Title: Hepatotoxicity by bosentan in a patient with portopulmonary hypertension: a case-report and review of the literature.
Journal: Journal of gastrointestinal and liver diseases : JGLD 20110301
Title: [Changes long term prognosis of 17 patients with pulmonary artery hypertension].
Journal: Revista medica de Chile 20110301
Title: Endothelin receptor antagonists as disease modifiers in systemic sclerosis.
Journal: Inflammation & allergy drug targets 20110201
Title: Effects of multiple doses of ambrisentan on the pharmacokinetics of a single dose of digoxin in healthy volunteers.
Journal: Journal of clinical pharmacology 20110101
Title: Safety and efficacy of ambrisentan for the treatment of portopulmonary hypertension.
Journal: Chest 20110101
Title: Identification of clinically used drugs that activate pregnane X receptors.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20110101
Title: Availability of and access to orphan drugs: an international comparison of pharmaceutical treatments for pulmonary arterial hypertension, Fabry disease, hereditary angioedema and chronic myeloid leukaemia.
Journal: PharmacoEconomics 20110101
Title: Effect of transition from sitaxsentan to ambrisentan in pulmonary arterial hypertension.
Journal: Vascular health and risk management 20110101
Title: Pulmonary vascular complications of chronic liver disease: Pathophysiology, imaging, and treatment.
Journal: Annals of thoracic medicine 20110101
Title: Short term effects of exercise training on exercise capacity and quality of life in patients with pulmonary arterial hypertension: protocol for a randomised controlled trial.
Journal: BMC pulmonary medicine 20110101
Title: [Pulmonary arterial hypertension: changing approaches to management].
Journal: Kardiologiia 20110101
Title: Recent trends in pulmonary arterial hypertension.
Journal: Lung India : official organ of Indian Chest Society 20110101
Title: Therapeutic strategies in pulmonary hypertension.
Journal: Frontiers in pharmacology 20110101
Title: Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice.
Journal: Arthritis research & therapy 20110101
Title: Does market exclusivity hinder the development of Follow-on Orphan Medicinal Products in Europe?
Journal: Orphanet journal of rare diseases 20110101
Title: Diagnosis and management of pulmonary arterial hypertension.
Journal: Pulmonary medicine 20110101
Title: Anaesthesia Management of Caesarean Section in Two Patients with Eisenmenger's Syndrome.
Journal: Anesthesiology research and practice 20110101
Title: Diagnostic and therapeutic algorithm for pulmonary arterial hypertension.
Journal: Pulmonary circulation 20110101
Title: Overview of current therapeutic approaches for pulmonary hypertension.
Journal: Pulmonary circulation 20110101
Title: Vascular involvement in systemic sclerosis (scleroderma).
Journal: Journal of inflammation research 20110101
Title: Assessment of daily life physical activities in pulmonary arterial hypertension.
Journal: PloS one 20110101
Title: Endothelin Receptor Antagonists for the Treatment of Raynaud's Phenomenon and Digital Ulcers in Systemic Sclerosis.
Journal: International journal of rheumatology 20110101
Title: Long-term effects of intravenous iloprost in patients with idiopathic pulmonary arterial hypertension deteriorating on non-parenteral therapy.
Journal: BMC pulmonary medicine 20110101
Title: Effect and safety of mycophenolate mofetil in idiopathic pulmonary fibrosis.
Journal: Pulmonary medicine 20110101
Title: Surgical treatment of pulmonary hypertension: Lung transplantation.
Journal: Pulmonary circulation 20110101
Title: Early intervention in pulmonary arterial hypertension associated with systemic sclerosis: an essential component of disease management.
Journal: European respiratory review : an official journal of the European Respiratory Society 20101201
Title: The Adult Patient with Eisenmenger Syndrome: A Medical Update after Dana Point Part II: Medical Treatment - Study Results.
Journal: Current cardiology reviews 20101101
Title: Potential for pharmacokinetic interactions between ambrisentan and cyclosporine.
Journal: Clinical pharmacology and therapeutics 20101001
Title: Pulmonary arterial hypertension: from the kingdom of the near-dead to multiple clinical trial meta-analyses.
Journal: European heart journal 20100901
Title: Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes.
Journal: Canadian journal of physiology and pharmacology 20100601
Title: Combined vasomodulatory therapy for severe pulmonary hypertension in chronic hypersensitivity pneumonitis.
Journal: Medical science monitor : international medical journal of experimental and clinical research 20100501
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20100501
Title: [Pulmonary circulation: contributions of the year 2009].
Journal: Archivos de bronconeumologia 20100301
Title: Long-term outcomes with ambrisentan monotherapy in pulmonary arterial hypertension.
Journal: Journal of cardiac failure 20100201
Title: [Endothelin receptor antagonists in the new European guidelines on pulmonary hypertension].
Journal: Revue des maladies respiratoires 20100201
Title: Pharmacotherapy in pulmonary arterial hypertension: a systematic review and meta-analysis.
Journal: Respiratory research 20100101
Title: Pulmonary arterial hypertension in connective tissue diseases.
Journal: Cardiology in review 20100101
Title: Hemodynamics in pulmonary arterial hypertension (PAH): do they explain long-term clinical outcomes with PAH-specific therapy?
Journal: BMC cardiovascular disorders 20100101
Title: Oral Therapies for the treatment of pulmonary arterial hypertension: a population-based cost-minimization analysis.
Journal: Applied health economics and health policy 20100101
Title: Portopulmonary hypertension.
Journal: Annals of thoracic medicine 20100101
Title: Effect of steady-state ambrisentan on the pharmacokinetics of a single dose of the oral contraceptive norethindrone (norethisterone) 1 mg/ethinylestradiol 35 microg in healthy subjects: an open-label, single-sequence, single-centre study.
Journal: Clinical drug investigation 20100101
Title: Pharmacotherapeutic management of pulmonary arterial hypertension.
Journal: Cardiology in review 20100101
Title: The emergence of oral tadalafil as a once-daily treatment for pulmonary arterial hypertension.
Journal: Vascular health and risk management 20100101
Title: Update on the clinical utility of sildenafil in the treatment of pulmonary arterial hypertension.
Journal: Drug design, development and therapy 20100101
Title: Adult patients with pulmonary arterial hypertension due to congenital heart disease: a review on advanced medical treatment with bosentan.
Journal: Therapeutics and clinical risk management 20100101
Title: Effects of rifampicin (rifampin) on the pharmacokinetics and safety of ambrisentan in healthy subjects: a single-sequence, open-label study.
Journal: Clinical drug investigation 20100101
Title: Inhaled treprostinil and pulmonary arterial hypertension.
Journal: Vascular health and risk management 20100101
Title: Phosphodiesterase-5 inhibitors in management of pulmonary hypertension: safety, tolerability, and efficacy.
Journal: Drug, healthcare and patient safety 20100101
Title: No clinically relevant pharmacokinetic and safety interactions of ambrisentan in combination with tadalafil in healthy volunteers.
Journal: Journal of pharmaceutical sciences 20091201
Title: Endothelin receptor antagonists for pulmonary hypertension in adult patients with sickle cell disease.
Journal: British journal of haematology 20091201
Title: [Endothelin receptor antagonists - their role in pulmonary medicine].
Journal: Revue des maladies respiratoires 20091201
Title: Long-term ambrisentan therapy for the treatment of pulmonary arterial hypertension.
Journal: Journal of the American College of Cardiology 20091117
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20091101
Title: Can we improve outcome of congenital diaphragmatic hernia?
Journal: Pediatric surgery international 20090901
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20090901
Title: Ambrisentan, an endothelin receptor type A-selective endothelin receptor antagonist, for the treatment of pulmonary arterial hypertension.
Journal: Expert opinion on pharmacotherapy 20090801
Title: Use of inhaled iloprost in an infant with bronchopulmonary dysplasia and pulmonary artery hypertension.
Journal: Korean circulation journal 20090801
Title: Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
Journal: Journal of clinical pharmacology 20090601
Title: Pulmonary arterial hypertension: the most devastating vascular complication of systemic sclerosis.
Journal: Rheumatology (Oxford, England) 20090601
Title: Small-molecule endothelin receptor antagonists: a review of patenting activity across therapeutic areas.
Journal: IDrugs : the investigational drugs journal 20090601
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20090601
Title: The pharmacokinetics and pharmacodynamics of warfarin in combination with ambrisentan in healthy volunteers.
Journal: British journal of clinical pharmacology 20090501
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20090401
Title: Ambrisentan: new drug. Too risky in mildly symptomatic pulmonary hypertension.
Journal: Prescrire international 20090401
Title: A meta-analysis of randomized controlled trials in pulmonary arterial hypertension.
Journal: European heart journal 20090201
Title: Ambrisentan therapy in patients with pulmonary arterial hypertension who discontinued bosentan or sitaxsentan due to liver function test abnormalities.
Journal: Chest 20090101
Title: [Pulmonary arterial hypertension: a voyage around the year 2008].
Journal: Archivos de bronconeumologia 20090101
Title: Pulmonary arterial hypertension in children: a medical update.
Journal: Indian journal of pediatrics 20090101
Title: Review of inhaled iloprost for the control of pulmonary artery hypertension in children.
Journal: Vascular health and risk management 20090101
Title: New concepts in the invasive and non invasive evaluation of remodelling of the right ventricle and pulmonary vasculature in pulmonary arterial hypertension.
Journal: The open respiratory medicine journal 20090101
Title: Endothelin-1 inhibition by ambrisentan as a potential treatment adjunct after debulking surgery in epithelial ovarian cancer.
Journal: Oncology research 20090101
Title: Treatment of pediatric pulmonary hypertension.
Journal: Vascular health and risk management 20090101
Title: Oral therapies for the treatment of pulmonary arterial hypertension: a population-based cost-minimization analysis.
Journal: Applied health economics and health policy 20090101
Title: Bosentan in the treatment of pulmonary arterial hypertension with the focus on the mildly symptomatic patient.
Journal: Vascular health and risk management 20090101
Title: Cost-utility of treatments for pulmonary arterial hypertension: a Markov state-transition decision analysis model.
Journal: Clinical drug investigation 20090101
Title: Safety and tolerability of bosentan in the management of pulmonary arterial hypertension.
Journal: Drug design, development and therapy 20090101
Title: Therapeutic methods used in patients with Eisenmenger syndrome.
Journal: Cardiology journal 20090101
Title: Integrated care and optimal management of pulmonary arterial hypertension.
Journal: Journal of multidisciplinary healthcare 20090101
Title: Pharmacokinetics and safety of ambrisentan in combination with sildenafil in healthy volunteers.
Journal: Journal of clinical pharmacology 20081201
Title: Ambrisentan and its role in the management of pulmonary arterial hypertension.
Journal: Drugs of today (Barcelona, Spain : 1998) 20081201
Title: Role of ambrisentan in the management of pulmonary hypertension.
Journal: The Annals of pharmacotherapy 20081101
Title: [Specific drugs for the treatment of pulmonary arterial hypertension - current status].
Journal: Deutsche medizinische Wochenschrift (1946) 20081001
Title: Optimizing endothelin receptor antagonist use in the management of pulmonary arterial hypertension.
Journal: Vascular health and risk management 20081001
Title: Pulmonary arterial hypertension: on the way to a manageable disease.
Journal: Current opinion in investigational drugs (London, England : 2000) 20080901
Title: Inhibition of endothelin receptors in the treatment of pulmonary arterial hypertension: does selectivity matter?
Journal: European heart journal 20080801
Title: [Current treatment of systemic sclerosis. Part II. Vascular and antifibrotic treatment].
Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20080801
Title: The management of pulmonary hypertension in children.
Journal: Archives of disease in childhood 20080701
Title: Ambrisentan for the treatment of pulmonary arterial hypertension: results of the ambrisentan in pulmonary arterial hypertension, randomized, double-blind, placebo-controlled, multicenter, efficacy (ARIES) study 1 and 2.
Journal: Circulation 20080610
Title: The status of pulmonary arterial hypertension in 2008.
Journal: Circulation 20080610
Title: [Systemic sclerosis].
Journal: Medizinische Monatsschrift fur Pharmazeuten 20080501
Title: Ambrisentan for the management of pulmonary arterial hypertension.
Journal: Clinical therapeutics 20080501
Title: [Treatment of pulmonary arterial hypertension by endothelin receptor antagonists in 2008].
Journal: La Revue de medecine interne 20080401
Title: The endothelin system as a therapeutic target in cardiovascular disease: great expectations or bleak house?
Journal: British journal of pharmacology 20080301
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20080301
Title: Endothelin receptor antagonists in pulmonary arterial hypertension.
Journal: The European respiratory journal 20080201
Title: Acute right ventricular failure in the setting of acute pulmonary embolism or chronic pulmonary hypertension: a detailed review of the pathophysiology, diagnosis, and management.
Journal: Current cardiology reviews 20080201
Title: Endothelin receptor antagonists for pulmonary arterial hypertension: rationale and place in therapy.
Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20080101
Title: Effects of selective and unselective endothelin-receptor antagonists on prostacyclin synthase gene expression in experimental pulmonary hypertension.
Journal: Scandinavian journal of clinical and laboratory investigation 20080101
Title: Endothelin receptor antagonism: role in the treatment of pulmonary arterial hypertension related to scleroderma.
Journal: Drugs 20080101
Title: Ambrisentan.
Journal: Drugs 20080101
Title: Pulmonary hypertension: past, present and future.
Journal: Annals of thoracic medicine 20080101
Title: Ambrisentan for the treatment of pulmonary arterial hypertension.
Journal: Drug design, development and therapy 20080101
Title: Review of bosentan in the management of pulmonary arterial hypertension.
Journal: Vascular health and risk management 20071201
Title: Ambrisentan (Letairis) for pulmonary arterial hypertension.
Journal: The Medical letter on drugs and therapeutics 20071022
Title: Systematic review of randomised, double-blind clinical trials of oral agents conducted in patients with pulmonary arterial hypertension.
Journal: International journal of clinical practice 20071001
Title: Expert opinion on available options treating pulmonary arterial hypertension.
Journal: Expert opinion on pharmacotherapy 20071001
Title: Ambrisentan.
Journal: Nature reviews. Drug discovery 20070901
Title: Therapeutic challenges for systemic sclerosis: facts and future targets.
Journal: Annals of the New York Academy of Sciences 20070901
Title: New drug approved for pulmonary arterial hypertension.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070801
Title: EndothelinA receptor antagonist BSF-208075 causes immune modulation and neuroprotection after stroke in gerbils.
Journal: Brain research 20070709
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20070401
Title: Pathophysiological role of platelets in acute experimental pancreatitis: influence of endothelin A receptor blockade.
Journal: Cell and tissue research 20070301
Title: Endothelin receptor antagonists in the treatment of pulmonary arterial hypertension.
Journal: Clinics in chest medicine 20070301
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20070301
Title: A review of pulmonary arterial hypertension: role of ambrisentan.
Journal: Vascular health and risk management 20070201
Title: Therapeutic targets in systemic sclerosis.
Journal: Arthritis research & therapy 20070101
Title: New drugs: ambrisentan, temsirolimus, and eculizumab.
Journal: Journal of the American Pharmacists Association : JAPhA 20070101
Title: [Pulmonary hypertension and right ventricular failure. Part XI. Endothelin receptor blockers in the treatment of primary pulmonary arterial hypertension].
Journal: Kardiologiia 20070101
Title: Management of pulmonary arterial hypertension associated with congenital heart disease.
Journal: Romanian journal of internal medicine = Revue roumaine de medecine interne 20070101
Title: Tadalafil: the evidence for its clinical potential in the treatment of pulmonary arterial hypertension.
Journal: Core evidence 20070101
Title: [Treatment of pulmonary arterial hypertension: endothelin-receptor antagonists].
Journal: Deutsche medizinische Wochenschrift (1946) 20061208
Title: Endothelin receptor antagonism in pulmonary arterial hypertension--a role for selective ET(A) inhibition?
Journal: Current medical research and opinion 20061201
Title: Medical therapies for chronic thromboembolic pulmonary hypertension: an evolving treatment paradigm.
Journal: Proceedings of the American Thoracic Society 20060901
Title: Endothelin receptor antagonists.
Journal: Pharmacology & therapeutics 20060601
Title: Profile of past and current clinical trials involving endothelin receptor antagonists: the novel '-sentan' class of drug.
Journal: Experimental biology and medicine (Maywood, N.J.) 20060601
Title: Endothelin antagonism prevents diabetic retinopathy in NOD mice: a potential role of the angiogenic factor adrenomedullin.
Journal: Experimental biology and medicine (Maywood, N.J.) 20060601
Title: Attenuation of proinflammatory gene expression and microcirculatory disturbances by endothelin A receptor blockade after orthotopic liver transplantation in pigs.
Journal: Surgery 20060101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20060101
Title: Ambrisentan, a non-peptide endothelin receptor antagonist.
Journal: Cardiovascular drug reviews 20060101
Title: Drug Insight: endothelin-receptor antagonists for pulmonary arterial hypertension in systemic rheumatic diseases.
Journal: Nature clinical practice. Rheumatology 20051201
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20051001
Title: Ambrisentan therapy for pulmonary arterial hypertension.
Journal: Journal of the American College of Cardiology 20050802
Title: Ambrisentan for pulmonary arterial hypertension.
Journal: Future cardiology 20050701
Title: [Emerging therapies for the treatment of pulmonary arterial hypertension].
Journal: Herz 20050601
Title: [Treatment algorithm for pulmonary arterial hypertension].
Journal: Herz 20050601
Title: Improvement of postischemic hepatic microcirculation after endothelinA receptor blockade--endothelin antagonism influences platelet-endothelium interactions.
Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20050201
Title: Drug treatment of pulmonary arterial hypertension: current and future agents.
Journal: Drugs 20050101
Title: Effects of ET(A) receptor antagonism on proinflammatory gene expression and microcirculation following hepatic ischemia/reperfusion.
Journal: Microcirculation (New York, N.Y. : 1994) 20050101
Title: Changes of vasoregulatory gene expression following hepatic ischemia/reperfusion and treatment with endothelin-A receptor blockade.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Endothelin-A receptor blockade improves postischemic hepatic microhemodynamics.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Gateways to clinical trials.
Journal: Methods and findings in experimental and clinical pharmacology 20041001
Title: Endothelin receptor antagonists in pulmonary arterial hypertension.
Journal: Journal of the American College of Cardiology 20040616
Title: Endothelin receptor antagonists are not beneficial in the therapy of acute experimental pancreatitis.
Journal: Langenbeck's archives of surgery 20040601
Title: Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists.
Journal: Journal of medicinal chemistry 20040520
Title: Influence of a selective endothelin(A) receptor antagonist on the quantitative mRNA expression and the immunohistochemistry of vasoactive mediators after pancreas transplantation.
Journal: Transplantation proceedings 20030901
Title: Cerebrovascular characterization of the novel nonpeptide endothelin-A receptor antagonist LU 208075.
Journal: Clinical neuropharmacology 20030101
Title: Ambrisentan (Myogen).
Journal: Current opinion in investigational drugs (London, England : 2000) 20021001
Title: Administration of a selective endothelin-a receptor antagonist (BSF 208075) improves hepatic warm ischemia/reperfusion injury in pigs.
Journal: Transplantation proceedings 20020901
Title: Effect of the novel endothelin(A) receptor antagonist LU 208075 on contraction and relaxation of isolated rat basilar artery.
Journal: Clinical science (London, England : 1979) 20020801
Title: Endothelin A-receptor blockade in experimental diabetes improves glucose balance and gastrointestinal function.
Journal: Clinical science (London, England : 1979) 20020801
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