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111-77-3,MFCD00002871
Catalog No.:AA0034NU

111-77-3 | 2-(2-Methoxyethoxy)ethanol

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25g
98% (stabilized with BHT)
in stock  
$6.00   $4.00
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100g
98% (stabilized with BHT)
in stock  
$7.00   $5.00
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500g
98% (stabilized with BHT)
in stock  
$12.00   $8.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0034NU
Chemical Name:
2-(2-Methoxyethoxy)ethanol
CAS Number:
111-77-3
Molecular Formula:
C5H12O3
Molecular Weight:
120.1470
MDL Number:
MFCD00002871
SMILES:
COCCOCCO
NSC Number:
2261
UN Number:
2810
Properties
Properties
 
BP:
194°C at 760 mmHg  
Form:
Solid  
MP:
-70 °C  
Refractive Index:
n20/D 1.426  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
38.7  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
-0.9  

Upstream Synthesis Route

[1]Patent:US2018/230094,2018,A1,.Locationinpatent:Paragraph0094;0095

[1]Patent:US2004/44253,2004,A1,.Locationinpatent:Page3

[1]Organicletters,2003,vol.5,#22,p.4085-4088

[1]Patent:US6372735,2002,B1,

[1]Patent:US7754909,2010,B1,.Locationinpatent:Page/Pagecolumn4-5;10

Downstream Synthesis Route
111-77-3    120-36-5   
2-(2,4-dichloro-phenoxy)-propionicacid-2-(2-methoxy-ethoxy)-ethylester 

[1]Patent:US2759965,1953,

[1]Chaput,G.etal.[CanadianJournalofChemistry,1975,vol.53,p.2240-2246]

[1]SpectrochimicaActaPartA:MolecularandBiomolecularSpectroscopy,2003,vol.59,p.1631-1641

[2]Synthesis,2003,p.509-512

[3]CollectionofCzechoslovakChemicalCommunications,1976,vol.41,p.1248-1252

[4]JournalofMedicinalChemistry,1995,vol.38,p.1067-1083

[5]TetrahedronLetters,2007,vol.48,p.4813-4815

[6]BioorganicandMedicinalChemistryLetters,2003,vol.13,p.1381-1384

[7]Patent:US2017/253569,2017,A1.Locationinpatent:Paragraph1254-1255

[8]RSCAdvances,2018,vol.8,p.36025-36033

[1]RussianJournalofAppliedChemistry,1993,vol.66,p.152-155    ZhurnalPrikladnoiKhimii(Sankt-Peterburg,RussianFederation),1993,vol.66,p.182-185

[1]JournalofOrganicChemistry,1985,vol.50,p.3717-3721

[2]JournalofOrganicChemistry,1985,vol.50,p.3717-3721

Literature

Title: Detection of DNA damage in workers exposed to JP-8 jet fuel.

Journal: Mutation research 20120918

Title: Ligand-assisted rate acceleration in lanthanum(III) isopropoxide catalyzed transesterification of carboxylic esters.

Journal: Organic letters 20110204

Title: Lanthanum(III) isopropoxide catalyzed chemoselective transesterification of dimethyl carbonate and methyl carbamates.

Journal: Organic letters 20110204

Title: The impact of polyether chain length on the iron clearing efficiency and physiochemical properties of desferrithiocin analogues.

Journal: Journal of medicinal chemistry 20100408

Title: Carbonic anhydrase inhibitors: two-prong versus mono-prong inhibitors of isoforms I, II, IX, and XII exemplified by photochromic cis-1,2-alpha-dithienylethene derivatives.

Journal: Bioorganic & medicinal chemistry letters 20090301

Title: New water-soluble metal working fluids additives from phosphonic acid derivatives for aluminum alloy materials.

Journal: Journal of oleo science 20070101

Title: Comparison and evaluation of analysis procedures for the quantification of (2-methoxyethoxy)acetic acid in urine.

Journal: Analytical and bioanalytical chemistry 20050901

Title: Biomonitoring of 2-(2-alkoxyethoxy)ethanols by analysing urinary 2-(2-alkoxyethoxy)acetic acids.

Journal: Toxicology letters 20050328

Title: A Test Procedure for the Determination of (2-Methoxyethoxy)acetic Acid in Urine from Jet Fuel-Exposed Mice.

Journal: Toxicology mechanisms and methods 20050101

Title: Mechanism of the transition between lamellar and gyroid phases formed by a diblock copolymer in aqueous solution.

Journal: Langmuir : the ACS journal of surfaces and colloids 20041207

Title: Procedure for the quantification of the biomarker (2-methoxyethoxy)acetic acid in human urine samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030925

Title: Tyrosine-bearing polyphosphazenes.

Journal: Biomacromolecules 20030101

Title: Selective induction of secondary metabolism in Phaseolus lunatus by 6-substituted indanoyl isoleucine conjugates.

Journal: Phytochemistry 20021201

Title: Identification of rat urinary and biliary metabolites of esonarimod, a novel antirheumatic drug, using liquid chromatography/electrospray ionization tandem mass spectrometry with postcolumn addition of 2-(2-methoxyethoxy)ethanol, a signal-enhancing modifier.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601

Title: A subchronic dermal exposure study of diethylene glycol monomethyl ether and ethylene glycol monomethyl ether in the male guinea pig.

Journal: Fundamental and applied toxicology : official journal of the Society of Toxicology 19860201

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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