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1110670-49-9
Catalog No.:AA008RKH

1110670-49-9 | 5-[(S)-(-)-2-(METHOXYMETHYL)PYRROLIDINO]SULFONYLISATIN

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$168.00   $117.00
- +
5mg
≥98%
in stock  
$539.00   $377.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008RKH
Chemical Name:
5-[(S)-(-)-2-(METHOXYMETHYL)PYRROLIDINO]SULFONYLISATIN
CAS Number:
1110670-49-9
Molecular Formula:
C14H16N2O5S
Molecular Weight:
324.3522
SMILES:
COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2
Properties
Computed Properties
 
Complexity:
570  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  
XLogP3:
0.3  

Literature

Title: Fluorinated isatin derivatives. Part 3. New side-chain fluoro-functionalized pyrrolidinyl sulfonyl isatins as potent caspase-3 and -7 inhibitors.

Journal: Future medicinal chemistry 20090801

Title: Fluorinated isatin derivatives. Part 2. New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis.

Journal: Journal of medicinal chemistry 20090611

Title: Biological targets for isatin and its analogues: Implications for therapy.

Journal: Biologics : targets & therapy 20070601

Title: The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent.

Journal: The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... 20070301

Title: A novel nonpeptidic caspase-3/7 inhibitor, (S)-(+)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin reduces myocardial ischemic injury.

Journal: European journal of pharmacology 20021205

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SDS
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Tags:1110670-49-9 Molecular Formula|1110670-49-9 MDL|1110670-49-9 SMILES|1110670-49-9 5-[(S)-(-)-2-(METHOXYMETHYL)PYRROLIDINO]SULFONYLISATIN
Catalog No.: AA008RKH
1110670-49-9
1110670-49-9 | 5-[(S)-(-)-2-(METHOXYMETHYL)PYRROLIDINO]SULFONYLISATIN
Pack Size： 1mg
Purity： ≥98%
in stock
$168.00 $117.00
Pack Size： 5mg
Purity： ≥98%
in stock
$539.00 $377.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA008RKH
Chemical Name: 5-[(S)-(-)-2-(METHOXYMETHYL)PYRROLIDINO]SULFONYLISATIN
CAS Number: 1110670-49-9
Molecular Formula: C14H16N2O5S
Molecular Weight: 324.3522
SMILES: COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2
Properties
Complexity: 570  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 22  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 4  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
XLogP3: 0.3  
Literature fold

Title: Fluorinated isatin derivatives. Part 3. New side-chain fluoro-functionalized pyrrolidinyl sulfonyl isatins as potent caspase-3 and -7 inhibitors.

Journal: Future medicinal chemistry20090801

Title: Fluorinated isatin derivatives. Part 2. New N-substituted 5-pyrrolidinylsulfonyl isatins as potential tools for molecular imaging of caspases in apoptosis.

Journal: Journal of medicinal chemistry20090611

Title: Biological targets for isatin and its analogues: Implications for therapy.

Journal: Biologics : targets & therapy20070601

Title: The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent.

Journal: The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...20070301

Title: A novel nonpeptidic caspase-3/7 inhibitor, (S)-(+)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin reduces myocardial ischemic injury.

Journal: European journal of pharmacology20021205

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