Home Other Building Blocks 1116743-46-4
1116743-46-4,MFCD25976852
Catalog No.:AA008ZRT

1116743-46-4 | SAR125844

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$15.00   $11.00
- +
5mg
98+%
in stock  
$36.00   $25.00
- +
10mg
98+%
in stock  
$54.00   $38.00
- +
25mg
98+%
in stock  
$91.00   $64.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008ZRT
Chemical Name:
SAR125844
CAS Number:
1116743-46-4
Molecular Formula:
C25H23FN8O2S2
Molecular Weight:
550.6309
MDL Number:
MFCD25976852
SMILES:
O=C(Nc1nc2c(s1)cc(cc2)Sc1nnc2n1nc(cc2)c1ccc(cc1)F)NCCN1CCOCC1
Properties

Downstream Synthesis Route

[1]Patent:US2010/298315,2010,A1.Locationinpatent:Page/Pagecolumn36

[1]Patent:US2010/298315,2010,A1.Locationinpatent:Page/Pagecolumn35

[1]JournalofMedicinalChemistry,2016,vol.59,p.7066-7074

[1]JournalofMedicinalChemistry,2016,vol.59,p.7066-7074

Literature

Title: Egile C, et al. The selective intravenous inhibitor of the MET tyrosine kinase SAR125844 inhibits tumor growth in MET-amplified cancer. Mol Cancer Ther. 2015 Feb;14(2):384-94.

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SDS
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