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111686-79-4,MFCD00882179
Catalog No.:AA008Y16

111686-79-4 | 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE

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10mg
≥99%(HPLC)
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50mg
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  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA008Y16
Chemical Name:
2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
CAS Number:
111686-79-4
Molecular Formula:
C17H21ClN2O
Molecular Weight:
304.8144
MDL Number:
MFCD00882179
SMILES:
NCC(=O)NC(c1ccccc1)(Cc1ccccc1)C.Cl
Properties
Computed Properties
 
Complexity:
306  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
Undefined Atom Stereocenter Count:
1  

Literature

Title: The cognitive and psychomotor effects of remacemide and carbamazepine in newly diagnosed epilepsy.

Journal: Epilepsy & behavior : E&B 20090301

Title: Isobolographic analysis of interactions between remacemide and conventional antiepileptic drugs in the mouse model of maximal electroshock.

Journal: Epilepsy & behavior : E&B 20070801

Title: Behavioral effects associated with chronic ketamine or remacemide exposure in rats.

Journal: Neurotoxicology and teratology 20070101

Title: Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice.

Journal: Experimental neurology 20040501

Title: Effects of manipulation of N-methyl-D-aspartate receptors on imipenem/cilastatin-induced seizures in rats.

Journal: The Indian journal of medical research 20040201

Title: Experimental therapeutics in Huntington's disease: are models useful for therapeutic trials?

Journal: Current opinion in neurology 20030801

Title: Lamotrigine and remacemide protect striatal neurons against in vitro ischemia: an electrophysiological study.

Journal: Experimental neurology 20030801

Title: Chronic exposure to NMDA receptor and sodium channel blockers during development in monkeys and rats: long-term effects on cognitive function.

Journal: Annals of the New York Academy of Sciences 20030501

Title: A double-blind, placebo-controlled study of remacemide hydrochloride in patients with refractory epilepsy following pre-surgical assessment.

Journal: Seizure 20020901

Title: Ontogeny of the N-methyl-D-aspartate (NMDA) receptor system and susceptibility to neurotoxicity.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20020701

Title: Differential effects of remacemide and desglycinyl-remacemide on epileptiform burst firing in the rat hippocampal slice.

Journal: Neuroscience letters 20020315

Title: Na(+) channel effects of remacemide and desglycinyl-remacemide in rat cortical synaptosomes.

Journal: European journal of pharmacology 20020301

Title: Remacemide hydrochloride as an add-on therapy in epilepsy: a randomized, placebo-controlled trial of three dose levels (300, 600 and 800 mg/day) in a B.I.D. regimen.

Journal: Seizure 20020301

Title: Remacemide hydrochloride as an add-on therapy in epilepsy: a randomized, placebo-controlled trial of three dose levels (300, 600 and 1200 mg/day) in a Q.I.D. regimen.

Journal: Seizure 20020301

Title: A comparative study of the effects of carbamazepine and the NMDA receptor antagonist remacemide on road tracking and car-following performance in actual traffic.

Journal: Psychopharmacology 20020101

Title: Assessing the potential toxicity of MK-801 and remacemide: chronic exposure in juvenile rhesus monkeys.

Journal: Neurotoxicology and teratology 20020101

Title: Levetiracetam, oxcarbazepine, remacemide and zonisamide for drug resistant localization-related epilepsy: a systematic review.

Journal: Epilepsy research 20010901

Title: Neuroprotective effects of lamotrigine and remacemide on excitotoxicity induced by glutamate agonists in isolated chick retina.

Journal: Experimental neurology 20010701

Title: A randomized, controlled trial of remacemide for motor fluctuations in Parkinson's disease.

Journal: Neurology 20010227

Title: A randomized, double-blind, placebo-controlled, ascending-dose tolerability and safety study of remacemide as adjuvant therapy in Parkinson's disease with response fluctuations.

Journal: Clinical neuropharmacology 20010101

Title: Differential effects of two NMDA receptor antagonists on cognitive-behavioral development in nonhuman primates I.

Journal: Neurotoxicology and teratology 20010101

Title: Differential effects of two NMDA receptor antagonists on cognitive--behavioral performance in young nonhuman primates II.

Journal: Neurotoxicology and teratology 20010101

Title: NR1 and NR2 subunit contributions to N-methyl-D-aspartate receptor channel blocker pharmacology.

Journal: The Journal of pharmacology and experimental therapeutics 19970201

Title: G C Palmer, et al. Neuroprotective properties of the uncompetitive NMDA receptor antagonist remacemide hydrochloride. Ann N Y Acad Sci. 1995 Sep 15;765:236-47; discussion 248.

Title: Sarah Santangeli, et al. Na+ channel effects of remacemide and desglycinyl-remacemide in rat cortical synaptosomes. Eur J Pharmacol. 2002 Mar 1;438(1-2):63-8.

Title: L K M Wright, et al. Behavioral effects associated with chronic ketamine or remacemide exposure in rats. Neurotoxicol Teratol. May-Jun 2007;29(3):348-59.

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Tags:111686-79-4 Molecular Formula|111686-79-4 MDL|111686-79-4 SMILES|111686-79-4 2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE