Home Imidazoles 112566-20-8
112566-20-8,MFCD09994219
Catalog No.:AA00926Q

112566-20-8 | Imidazo[1,2-a]pyridin-2-ol

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Price(USD)
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250mg
95%
in stock  
$13.00   $9.00
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1g
95%
in stock  
$34.00   $24.00
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5g
95%
in stock  
$107.00   $75.00
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10g
95%
in stock  
$180.00   $126.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00926Q
Chemical Name:
Imidazo[1,2-a]pyridin-2-ol
CAS Number:
112566-20-8
Molecular Formula:
C7H6N2O
Molecular Weight:
134.1353
MDL Number:
MFCD09994219
SMILES:
Oc1nc2n(c1)cccc2
Properties
Computed Properties
 
Complexity:
129  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
XLogP3:
1.7  

Upstream Synthesis Route

[1]Patent:US2010/130503,2010,A1,.Locationinpatent:Page/Pagecolumn26

Downstream Synthesis Route

[1]Patent:US2010/130503,2010,A1.Locationinpatent:Page/Pagecolumn26

[1]Patent:US2010/130503,2010,A1.Locationinpatent:Page/Pagecolumn26

Literature

Title: Effects of ZSET1446/ST101 on cognitive deficits and amyloid β deposition in the senescence accelerated prone mouse brain.

Journal: Journal of pharmacological sciences 20120101

Title: ST101 induces a novel 17 kDa APP cleavage that precludes Aβ generation in vivo.

Journal: Annals of neurology 20110501

Title: [Neurochemical mechanisms of a novel Alzheimer's disease therapeutics on improvement of cognition and depressive behavior].

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110401

Title: Pharmacologic Treatment with GABA(B) Receptor Agonist of Methamphetamine-Induced Cognitive Impairment in Mice.

Journal: Current neuropharmacology 20110301

Title: A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice.

Journal: PloS one 20110101

Title: Potential Antidepressant Role of Neurotransmitter CART: Implications for Mental Disorders.

Journal: Depression research and treatment 20110101

Title: A novel azaindolizinone derivative ZSET1446 (spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one) improves methamphetamine-induced impairment of recognition memory in mice by activating extracellular signal-regulated kinase 1/2.

Journal: The Journal of pharmacology and experimental therapeutics 20070201

Title: Effects of a novel cognitive enhancer, spiro[imidazo-[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446), on learning impairments induced by amyloid-beta1-40 in the rat.

Journal: The Journal of pharmacology and experimental therapeutics 20060601

Title: Antiamnesic effects of azaindolizinone derivative ZSET845 on impaired learning and decreased ChAT activity induced by amyloid-beta 25-35 in the rat.

Journal: Brain research 20020802

Title: Ameliorative effects of azaindolizinone derivative ZSET845 on scopolamine-induced deficits in passive avoidance and radial-arm maze learning in the rat.

Journal: Japanese journal of pharmacology 20011101

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