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113299-40-4,MFCD00870866
Catalog No.:AA0079D7

113299-40-4 | (R)-Bicalutamide

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Purity
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5mg
95%
in stock  
$116.00   $81.00
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10mg
95%
in stock  
$193.00   $135.00
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50mg
95%
in stock  
$682.00   $477.00
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1g
≥98%
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$12,224.00   $8,557.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0079D7
Chemical Name:
(R)-Bicalutamide
CAS Number:
113299-40-4
Molecular Formula:
C18H14F4N2O4S
Molecular Weight:
430.3734
MDL Number:
MFCD00870866
SMILES:
N#Cc1ccc(cc1C(F)(F)F)NC(=O)[C@](CS(=O)(=O)c1ccc(cc1)F)(O)C
Properties
Computed Properties
 
Complexity:
750  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
2.3  

Literature

Title: Development and validation of a highly sensitive LC-MS/MS-ESI method for the determination of bicalutamide in mouse plasma: application to a pharmacokinetic study.

Journal: Biomedical chromatography : BMC 20121201

Title: MUC1-C oncoprotein confers androgen-independent growth of human prostate cancer cells.

Journal: The Prostate 20121101

Title: In silico discovery of androgen receptor antagonists with activity in castration resistant prostate cancer.

Journal: Molecular endocrinology (Baltimore, Md.) 20121101

Title: Images in clinical medicine. Gynecomastia induced by prostate-cancer treatment.

Journal: The New England journal of medicine 20121011

Title: A synthetic decursin analog with increased in vivo stability suppresses androgen receptor signaling in vitro and in vivo.

Journal: Investigational new drugs 20121001

Title: Prostate-specific antigen response to deferred combined androgen blockade therapy using bicalutamide predicts survival after subsequent oestrogen and docetaxel therapies in patients with castration-resistant prostate cancer.

Journal: BJU international 20121001

Title: Editorial comment. Prostate-specific antigen response to deferred combined androgen blockade therapy using bicalutamide predicts survival after subsequent oestrogen and docetaxel therapies in patients with castration-resistant prostate cancer.

Journal: BJU international 20121001

Title: Steroid derivatives as pure antagonists of the androgen receptor.

Journal: The Journal of steroid biochemistry and molecular biology 20121001

Title: SGEF is overexpressed in prostate cancer and contributes to prostate cancer progression.

Journal: Oncology reports 20121001

Title: Androgens regulate Hedgehog signalling and proliferation in androgen-dependent prostate cells.

Journal: International journal of cancer 20120915

Title: Autophagy regulates lipolysis and cell survival through lipid droplet degradation in androgen-sensitive prostate cancer cells.

Journal: The Prostate 20120915

Title: Distinct expression and activity of GSK-3α and GSK-3β in prostate cancer.

Journal: International journal of cancer 20120915

Title: Putting the brakes on continued androgen receptor signaling in castration-resistant prostate cancer.

Journal: Molecular and cellular endocrinology 20120905

Title: A randomized trial comparing tamoxifen therapy vs. tamoxifen prophylaxis in bicalutamide-induced gynecomastia.

Journal: Clinical genitourinary cancer 20120901

Title: Structure-based virtual screening and identification of a novel androgen receptor antagonist.

Journal: The Journal of biological chemistry 20120831

Title: A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer.

Journal: Investigational new drugs 20120801

Title: Upfront androgen deprivation therapy with salvage radiation may improve biochemical outcomes in prostate cancer patients with post-prostatectomy rising PSA.

Journal: International journal of radiation oncology, biology, physics 20120801

Title: Combination therapy of antiandrogen and XIAP inhibitor for treating advanced prostate cancer.

Journal: Pharmaceutical research 20120801

Title: Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models.

Journal: International journal of oncology 20120801

Title: [Prostate carcinoma with squamous differentiation after combination endocrine therapy: a case report].

Journal: Hinyokika kiyo. Acta urologica Japonica 20120801

Title: Design, synthesis, and biological evaluation of nonsteroidal cycloalkane[d]isoxazole-containing androgen receptor modulators.

Journal: Journal of medicinal chemistry 20120726

Title: Elevation of c-FLIP in castrate-resistant prostate cancer antagonizes therapeutic response to androgen receptor-targeted therapy.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20120715

Title: A competitive inhibitor that reduces recruitment of androgen receptor to androgen-responsive genes.

Journal: The Journal of biological chemistry 20120706

Title: Phase I trial of tremelimumab in combination with short-term androgen deprivation in patients with PSA-recurrent prostate cancer.

Journal: Cancer immunology, immunotherapy : CII 20120701

Title: Chemical castration and anti-androgens induce differential gene expression in prostate cancer.

Journal: The Journal of pathology 20120701

Title: Androgens inhibit the stimulatory action of 17β-estradiol on normal human breast tissue in explant cultures.

Journal: The Journal of clinical endocrinology and metabolism 20120701

Title: Estrogen receptor beta dependent attenuation of cytokine-induced cyclooxygenase-2 by androgens in human brain vascular smooth muscle cells and rat mesenteric arteries.

Journal: Steroids 20120701

Title: Antitumor agents 290. Design, synthesis, and biological evaluation of new LNCaP and PC-3 cytotoxic curcumin analogs conjugated with anti-androgens.

Journal: Bioorganic & medicinal chemistry 20120701

Title: Effects of the anti-androgen, bicalutamide, in a reduced life-cycle study with the fathead minnow (Pimephales promelas).

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20120615

Title: Androgen receptor footprint on the way to prostate cancer progression.

Journal: World journal of urology 20120601

Title: Carbidopa enhances antitumoral activity of bicalutamide on the androgen receptor-axis in castration-resistant prostate tumors.

Journal: The Prostate 20120601

Title: Tanshinones from Chinese medicinal herb Danshen (Salvia miltiorrhiza Bunge) suppress prostate cancer growth and androgen receptor signaling.

Journal: Pharmaceutical research 20120601

Title: Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostate cancer LNCaP cells.

Journal: Cancer science 20120601

Title: Sorafenib decreases proliferation and induces apoptosis of prostate cancer cells by inhibition of the androgen receptor and Akt signaling pathways.

Journal: Endocrine-related cancer 20120601

Title: The long-term results with delayed-combined androgen blockade therapy in local or locally advanced prostate cancer.

Journal: Japanese journal of clinical oncology 20120601

Title: Identification and characterization of MEL-3, a novel AR antagonist that suppresses prostate cancer cell growth.

Journal: Molecular cancer therapeutics 20120601

Title: Open, multi-center, phase IV study to assess the efficacy and tolerability of triptorelin in Taiwanese patients with advanced prostate cancer.

Journal: Journal of the Chinese Medical Association : JCMA 20120601

Title: Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.

Journal: Cancer research 20120501

Title: Estrogen receptor-α and sex steroid hormones regulate Toll-like receptor-9 expression and invasive function in human breast cancer cells.

Journal: Breast cancer research and treatment 20120401

Title: Cost-effectiveness analysis of degarelix for advanced hormone-dependent prostate cancer.

Journal: BJU international 20120401

Title: [Impact of androgen deprivation on the lipid profile and atherogenic risk in prostate cancer patients].

Journal: Actas urologicas espanolas 20120401

Title: Design, synthesis, and biological evaluation of 4-arylmethyl-1-phenylpyrazole and 4-aryloxy-1-phenylpyrazole derivatives as novel androgen receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20120401

Title: Development and validation of stability-indicating HPLC and UPLC methods for the determination of bicalutamide.

Journal: Journal of chromatographic science 20120401

Title: Phase II study of long-term androgen suppression with bevacizumab and intensity-modulated radiation therapy (IMRT) in high-risk prostate cancer.

Journal: International journal of radiation oncology, biology, physics 20120315

Title: ARN-509: a novel antiandrogen for prostate cancer treatment.

Journal: Cancer research 20120315

Title: Androgen receptor serine 81 phosphorylation mediates chromatin binding and transcriptional activation.

Journal: The Journal of biological chemistry 20120309

Title: DCE and DW MRI in monitoring response to androgen deprivation therapy in patients with prostate cancer: a feasibility study.

Journal: Magnetic resonance in medicine 20120301

Title: Learning from estrogen receptor antagonism: structure-based identification of novel antiandrogens effective against multiple clinically relevant androgen receptor mutants.

Journal: Chemical biology & drug design 20120301

Title: Zyflamend inhibits the expression and function of androgen receptor and acts synergistically with bicalutimide to inhibit prostate cancer cell growth.

Journal: The Prostate 20120201

Title: mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer.

Journal: Endocrine-related cancer 20120201

Title: A comparative assessment of α-lipoic acid N-phenylamides as non-steroidal androgen receptor antagonists both on and off gold nanoparticles.

Journal: Bioorganic chemistry 20120201

Title: Synthesis and characterization of bicalutamide-loaded magnetic nanoparticles as anti-tumor drug carriers.

Journal: Journal of nanoscience and nanotechnology 20120201

Title: A physiological role for androgen actions in the absence of androgen receptor DNA binding activity.

Journal: Molecular and cellular endocrinology 20120102

Title: Galbanic acid decreases androgen receptor abundance and signaling and induces G1 arrest in prostate cancer cells.

Journal: International journal of cancer 20120101

Title: Higher percentage of positive biopsy cores and Gleason score are associated with a greater degree of prostate gland shrinkage after neoadjuvant cytoreductive therapy.

Journal: Brachytherapy 20120101

Title: Understanding the performance of melt-extruded poly(ethylene oxide)-bicalutamide solid dispersions: characterisation of microstructural properties using thermal, spectroscopic and drug release methods.

Journal: Journal of pharmaceutical sciences 20120101

Title: A case of definitive therapy for localised prostate cancer: report of a urological nightmare.

Journal: Advances in urology 20120101

Title: Androgen receptor expression is a biological marker for androgen sensitivity in high grade serous epithelial ovarian cancer.

Journal: Gynecologic oncology 20120101

Title: 5α-reductase inhibitors, antiviral and anti-tumor activities of some steroidal cyanopyridinone derivatives.

Journal: International journal of biological macromolecules 20120101

Title: Combined treatment with bicalutamide and anastrozole in a young boy with peripheral precocious puberty due to McCune-Albright Syndrome.

Journal: Endocrine journal 20120101

Title: Management of high-risk localized prostate cancer.

Journal: Advances in urology 20120101

Title: Short-term clinicopathological outcome of neoadjuvant chemohormonal therapy comprising complete androgen blockade, followed by treatment with docetaxel and estramustine phosphate before radical prostatectomy in Japanese patients with high-risk localized prostate cancer.

Journal: World journal of surgical oncology 20120101

Title: The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases.

Journal: Advances in urology 20120101

Title: A network flow approach to predict drug targets from microarray data, disease genes and interactome network - case study on prostate cancer.

Journal: Journal of clinical bioinformatics 20120101

Title: Abiraterone acetate: oral androgen biosynthesis inhibitor for treatment of castration-resistant prostate cancer.

Journal: Drug design, development and therapy 20120101

Title: Molecular basis of triple negative breast cancer and implications for therapy.

Journal: International journal of breast cancer 20120101

Title: Expression of toll-like receptors on breast tumors: taking a toll on tumor microenvironment.

Journal: International journal of breast cancer 20120101

Title: Androgenic suppression combined with radiotherapy for the treatment of prostate adenocarcinoma: a systematic review.

Journal: BMC cancer 20120101

Title: The relative bioavailability study and fasting and fed states pharmacokinetics of bicalutamide 50-mg tablets in healthy Chinese volunteers.

Journal: Arzneimittel-Forschung 20120101

Title: Androgen-regulated transcriptional control of sialyltransferases in prostate cancer cells.

Journal: PloS one 20120101

Title: ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors.

Journal: Neoplasia (New York, N.Y.) 20120101

Title: Mitosis phase enrichment with identification of mitotic centromere-associated kinesin as a therapeutic target in castration-resistant prostate cancer.

Journal: PloS one 20120101

Title: Tri-Modality therapy with I-125 brachytherapy, external beam radiation therapy, and short- or long-term hormone therapy for high-risk localized prostate cancer (TRIP): study protocol for a phase III, multicenter, randomized, controlled trial.

Journal: BMC cancer 20120101

Title: Prostate radiation in non-metastatic castrate refractory prostate cancer provides an interesting insight into biology of prostate cancer.

Journal: Radiation oncology (London, England) 20120101

Title: Redefining hormone sensitive disease in advanced prostate cancer.

Journal: Advances in urology 20120101

Title: Photosensitive drug eruption induced by bicalutamide within the UVB action spectrum.

Journal: European journal of dermatology : EJD 20120101

Title: Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening.

Journal: PloS one 20120101

Title: Retinoids regulate the formation and degradation of gap junctions in androgen-responsive human prostate cancer cells.

Journal: PloS one 20120101

Title: Castration-resistant prostate cancer: mechanisms, targets, and treatment.

Journal: Prostate cancer 20120101

Title: Three Years of Salvage IMRT for Prostate Cancer: Results of the Montpellier Cancer Center.

Journal: ISRN urology 20120101

Title: A real time Metridia luciferase based non-invasive reporter assay of mammalian cell viability and cytotoxicity via the β-actin promoter and enhancer.

Journal: PloS one 20120101

Title: McCune-Albright syndrome and the extraskeletal manifestations of fibrous dysplasia.

Journal: Orphanet journal of rare diseases 20120101

Title: Cardiometabolic complications after androgen deprivation therapy in a man with prostate cancer: effects of 3 years intermittent testosterone supplementation.

Journal: Frontiers in endocrinology 20120101

Title: Successful Treatment of Advanced Metastatic Prostate Cancer following Chemotherapy Based on Molecular Profiling.

Journal: Case reports in oncology 20120101

Title: PSA Response to Lenalidomide Therapy in a Pre-Treated Patient with Metastatic Prostate Cancer Refractory to Hormones and Chemotherapy: A Case Report.

Journal: Case reports in oncology 20120101

Title: Emerging targeted therapies for castration-resistant prostate cancer.

Journal: Frontiers in endocrinology 20120101

Title: Radiation, inflammation, and immune responses in cancer.

Journal: Frontiers in oncology 20120101

Title: Review of salvage therapy for biochemically recurrent prostate cancer: the role of imaging and rationale for systemic salvage targeted anti-prostate-specific membrane antigen radioimmunotherapy.

Journal: Advances in urology 20120101

Title: A study of plasma bicalutamide concentrations in hemodialysis patients.

Journal: Urologia internationalis 20120101

Title: Risk of hormone escape in a human prostate cancer model depends on therapy modalities and can be reduced by tyrosine kinase inhibitors.

Journal: PloS one 20120101

Title: [Clinico-pathological conference report: sudden deterioration of general condition, hypokalemia and diabetes in an elderly man].

Journal: Duodecim; laaketieteellinen aikakauskirja 20120101

Title: Prophylactic breast bud radiotherapy for patients taking bicalutamide: should this still be practised for patients with prostate cancer?

Journal: Case reports in oncological medicine 20120101

Title: Clinical efficacy of primary combined androgen blockade for Japanese men with clinically localized prostate cancer unsuitable for local definitive treatment: a single institution experience.

Journal: International journal of clinical oncology 20111201

Title: Interstitial pneumonitis induced by bicalutamide given for prostate cancer.

Journal: International journal of clinical oncology 20111201

Title: Circadian rhythm of hot flashes and activity levels among prostate cancer patients on androgen deprivation therapy.

Journal: The aging male : the official journal of the International Society for the Study of the Aging Male 20111201

Title: A novel steroidal antiandrogen targeting wild type and mutant androgen receptors.

Journal: Biochemical pharmacology 20111201

Title: Hormonal therapy promotes hormone-resistant phenotype by increasing DNMT activity and expression in prostate cancer models.

Journal: Endocrinology 20111201

Title: [Monotherapy versus combined androgen blockade for advanced/metastatic prostate cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20111201

Title: Liquid antisolvent precipitation process for solubility modulation of bicalutamide.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20111201

Title: [Renal metastasis from prostatic adenocarcinoma : a case report].

Journal: Hinyokika kiyo. Acta urologica Japonica 20111201

Title: Continence rate and oncological feasibility after total transurethral resection of the prostate as an alternative therapy for the treatment of prostate cancer: a pilot study.

Journal: International neurourology journal 20111201

Title: Modulation of the tumor cell death pathway by androgen receptor in response to cytotoxic stimuli.

Journal: Journal of cellular physiology 20111101

Title: Androgen deprivation therapy influences the uptake of 11C-choline in patients with recurrent prostate cancer: the preliminary results of a sequential PET/CT study.

Journal: European journal of nuclear medicine and molecular imaging 20111101

Title: Androgen suppresses proliferation of castration-resistant LNCaP 104-R2 prostate cancer cells through androgen receptor, Skp2, and c-Myc.

Journal: Cancer science 20111101

Title: Androgen deprivation therapy and the risk of coronary heart disease and heart failure in patients with prostate cancer: a nested case-control study in UK primary care.

Journal: Drug safety 20111101

Title: Multiple myeloma with biclonal gammopathy accompanied by prostate cancer.

Journal: The Korean journal of laboratory medicine 20111001

Title: Androgen receptor and heterogeneous nuclear ribonucleoprotein K colocalize in the nucleoplasm and are modulated by bicalutamide and 4-hydroxy-tamoxifen in prostatic cancer cell lines.

Journal: The Prostate 20110915

Title: Biological properties of androgen receptor pure antagonist for treatment of castration-resistant prostate cancer: optimization from lead compound to CH5137291.

Journal: The Prostate 20110901

Title: Hunterian Lecture. Characterisation of human prostate epithelial progenitor differentiation in response to androgens.

Journal: Annals of the Royal College of Surgeons of England 20110901

Title: [Prostate cancer with five different histological features: a case report and review of the literature].

Journal: Zhonghua nan ke xue = National journal of andrology 20110901

Title: Contemporary issues in precocious puberty.

Journal: Indian journal of endocrinology and metabolism 20110901

Title: Novel role of androgens in mitochondrial fission and apoptosis.

Journal: Molecular cancer research : MCR 20110801

Title: Epigenetic regulation of prostate cancer.

Journal: Clinical epigenetics 20110801

Title: Targeting androgen receptor in estrogen receptor-negative breast cancer.

Journal: Cancer cell 20110712

Title: A pure microcytic bladder carcinoma synchronous to prostatic adenocarcinoma.

Journal: Rare tumors 20110711

Title: Antivascular effects of neoadjuvant androgen deprivation for prostate cancer: an in vivo human study using susceptibility and relaxivity dynamic MRI.

Journal: International journal of radiation oncology, biology, physics 20110701

Title: Preliminary study with bicalutamide in heterosexual and homosexual patients with prostate cancer: a possible implication of androgens in male homosexual arousal.

Journal: BJU international 20110701

Title: Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies.

Journal: The Journal of clinical investigation 20110701

Title: Efficacy of alternative antiandrogen therapy for prostate cancer that relapsed after initial maximum androgen blockade.

Journal: Korean journal of urology 20110701

Title: Bicalutamide monotherapy preserves bone mineral density, muscle strength and has significant health-related quality of life benefits for osteoporotic men with prostate cancer.

Journal: BJU international 20110601

Title: Infiltration of tumour-associated macrophages in prostate biopsy specimens is predictive of disease progression after hormonal therapy for prostate cancer.

Journal: BJU international 20110601

Title: Androgen receptor-positive salivary duct carcinoma: a disease entity with promising new treatment options.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110601

Title: Up-regulation of insulin-like growth factor-binding protein 3 by 5-fluorouracil (5-FU) leads to the potent anti-proliferative effect of androgen deprivation therapy combined with 5-FU in human prostate cancer cell lines.

Journal: International journal of oncology 20110601

Title: [Results of 125-iodine seed implant with preplanning system in 250 patients with prostate cancer].

Journal: Actas urologicas espanolas 20110601

Title: LEF1 identifies androgen-independent epithelium in the developing prostate.

Journal: Molecular endocrinology (Baltimore, Md.) 20110601

Title: Words of wisdom. Re: Salvage therapy with bicalutamide 150 mg in nonmetastatic castration-resistant prostate cancer. Lodde M, Lacombe L, Fradet Y.

Journal: European urology 20110601

Title: [Alternative antiandrogen therapy with flutamide in patients with castration-resistant prostate cancer : a single center experience].

Journal: Hinyokika kiyo. Acta urologica Japonica 20110601

Title: Adjuvant androgen deprivation for high-risk prostate cancer after radical prostatectomy: SWOG S9921 study.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110520

Title: Mechanism of androgen receptor antagonism by bicalutamide in the treatment of prostate cancer.

Journal: Biochemistry 20110517

Title: The antiandrogenic effect of finasteride against a mutant androgen receptor.

Journal: Cancer biology & therapy 20110515

Title: Residual prostate cancer in patients treated with endocrine therapy with or without radical radiotherapy: a side study of the SPCG-7 randomized trial.

Journal: International journal of radiation oncology, biology, physics 20110501

Title: Comment on 'Androgen-hypersensitive preclinical model of prostate cancer' by Kawata et al.

Journal: The Prostate 20110501

Title: Drug safety is a barrier to the discovery and development of new androgen receptor antagonists.

Journal: The Prostate 20110401

Title: Androgen stimulates endothelial cell proliferation via an androgen receptor/VEGF/cyclin A-mediated mechanism.

Journal: American journal of physiology. Heart and circulatory physiology 20110401

Title: DHEA suppresses longitudinal bone growth by acting directly at growth plate through estrogen receptors.

Journal: Endocrinology 20110401

Title: Prostate adenocarcinoma with orbital metastasis in an HIV+ man.

Journal: The Canadian journal of urology 20110401

Title: Influence of short polyglutamine tracts and p160 coactivators on the transactivation of the androgen receptor.

Journal: Cancer biotherapy & radiopharmaceuticals 20110401

Title: Monte Carlo studies of drug nucleation 1: formation of crystalline clusters of bicalutamide in water.

Journal: The journal of physical chemistry. B 20110331

Title: Cell-cycle regulators cdk2ap1 and bicalutamide suppress malignant biological interactions between prostate cancer and bone cells.

Journal: The Prostate 20110301

Title: Serum testosterone level to predict the efficacy of sequential use of antiandrogens as second-line treatment following androgen deprivation monotherapy in patients with castration-resistant prostate cancer.

Journal: Japanese journal of clinical oncology 20110301

Title: Dehydroepiandrosterone fatty acyl esters in high density lipoprotein: interaction with human vascular endothelial cells and vascular responses ex vivo.

Journal: Steroids 20110301

Title: Hydroxyflutamide enhances cellular sensitivity to 5-fluorouracil by suppressing thymidylate synthase expression in bicalutamide-resistant human prostate cancer cells.

Journal: International journal of oncology 20110301

Title: Castration-resistant prostate cancer: targeted therapies and individualized treatment.

Journal: The oncologist 20110301

Title: Metastatic prostate cancer on the thyroid cartilage: unusual symptoms of prostatic adenocarcinoma. Case report.

Journal: Archivos espanoles de urologia 20110301

Title: Current treatment strategies for castration-resistant prostate cancer.

Journal: Korean journal of urology 20110301

Title: Saudi Oncology Society clinical management guidelines for prostate cancer.

Journal: Urology annals 20110301

Title: Phase I dose-escalation study of the novel antiandrogen BMS-641988 in patients with castration-resistant prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20110215

Title: Human prostate cell lines from normal and tumourigenic epithelia differ in the pattern and control of choline lipid headgroups released into the medium on stimulation of protein kinase C.

Journal: British journal of cancer 20110215

Title: Formation of bicalutamide nanodispersion for dissolution rate enhancement.

Journal: International journal of pharmaceutics 20110214

Title: Depression related to (neo)adjuvant hormonal therapy for prostate cancer.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110201

Title: Epithelial Hic-5/ARA55 expression contributes to prostate tumorigenesis and castrate responsiveness.

Journal: Oncogene 20110113

Title: Androgen receptor amplification is reflected in the transcriptional responses of Vertebral-Cancer of the Prostate cells.

Journal: Molecular and cellular endocrinology 20110101

Title: Combined androgen blockade for prostate cancer: review of efficacy, safety and cost-effectiveness.

Journal: Cancer science 20110101

Title: Daily phosphodiesterase type 5 inhibitor therapy as rescue for recurrent ischemic priapism after failed androgen ablation.

Journal: Journal of andrology 20110101

Title: IgG responses to tissue-associated antigens as biomarkers of immunological treatment efficacy.

Journal: Journal of biomedicine & biotechnology 20110101

Title: An 82-year-old Caucasian man with a ductal prostate adenocarcinoma with unusual cystoscopic appearance: a case report.

Journal: Journal of medical case reports 20110101

Title: Steroids up-regulate p66Shc longevity protein in growth regulation by inhibiting its ubiquitination.

Journal: PloS one 20110101

Title: Neoadjuvant hormonal therapy preceding radical prostatectomy for clinically localized prostate cancer: early postoperative complications and biochemical recurrence.

Journal: Korean journal of urology 20110101

Title: TRPV6 determines the effect of vitamin D3 on prostate cancer cell growth.

Journal: PloS one 20110101

Title: Androgen-induced cell migration: role of androgen receptor/filamin A association.

Journal: PloS one 20110101

Title: Cardiovascular risk during hormonal treatment in patients with prostate cancer.

Journal: Cancer management and research 20110101

Title: Cabazitaxel: a novel second-line treatment for metastatic castration-resistant prostate cancer.

Journal: Drug design, development and therapy 20110101

Title: Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer.

Journal: Breast cancer research : BCR 20110101

Title: Gynecomastia - evaluation and current treatment options.

Journal: Therapeutics and clinical risk management 20110101

Title: Penile metastasis from adenocarcinoma of the prostate in a patient with colorectal carcinoma.

Journal: Acta dermatovenerologica Croatica : ADC 20110101

Title: Effect of the dual endothelin receptor antagonist bosentan on untreatable skin ulcers in a patient with diabetes: a case report.

Journal: Journal of medical case reports 20110101

Title: [Disseminated carcinomatosis of the bone marrow in two patients with prostate cancer].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20110101

Title: MDM2 antagonists boost antitumor effect of androgen withdrawal: implications for therapy of prostate cancer.

Journal: Molecular cancer 20110101

Title: Regulation of PBX3 expression by androgen and Let-7d in prostate cancer.

Journal: Molecular cancer 20110101

Title: Expression of androgen receptor splice variants in prostate cancer bone metastases is associated with castration-resistance and short survival.

Journal: PloS one 20110101

Title: Duration of androgen deprivation therapy with maximum androgen blockade for localized prostate cancer.

Journal: BMC urology 20110101

Title: Effects of 1α,25 dihydroxyvitamin D3 and testosterone on miRNA and mRNA expression in LNCaP cells.

Journal: Molecular cancer 20110101

Title: Interpreting clinical assays for histone deacetylase inhibitors.

Journal: Cancer management and research 20110101

Title: GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state.

Journal: PloS one 20110101

Title: The metabolic advantage of tumor cells.

Journal: Molecular cancer 20110101

Title: Aromatase inhibitors in men: effects and therapeutic options.

Journal: Reproductive biology and endocrinology : RB&E 20110101

Title: Role of TMPRSS2-ERG gene fusion in negative regulation of PSMA expression.

Journal: PloS one 20110101

Title: Sipuleucel-T for therapy of asymptomatic or minimally symptomatic, castrate-refractory prostate cancer: an update and perspective among other treatments.

Journal: OncoTargets and therapy 20110101

Title: Detection of ligand-selective interactions of the human androgen receptor by SELDI-MS-TOF.

Journal: Methods in molecular biology (Clifton, N.J.) 20110101

Title: Positive HER-2 protein expression in circulating prostate cells and micro-metastasis, resistant to androgen blockage but not diethylstilbestrol.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20110101

Title: Peritoneal dissemination of prostate cancer due to laparoscopic radical prostatectomy: a case report.

Journal: Journal of medical case reports 20110101

Title: Modulation of androgen receptor signaling in hormonal therapy-resistant prostate cancer cell lines.

Journal: PloS one 20110101

Title: Six-month gonadotropin releasing hormone (GnRH) agonist depots provide efficacy, safety, convenience, and comfort.

Journal: Cancer management and research 20110101

Title: Androgens as therapy for androgen receptor-positive castration-resistant prostate cancer.

Journal: Journal of biomedical science 20110101

Title: Management options in triple-negative breast cancer.

Journal: Breast cancer : basic and clinical research 20110101

Title: Control of prostate cancer associated with withdrawal of a supplement containing folic acid, L-methyltetrahydrofolate and vitamin B12: a case report.

Journal: Journal of medical case reports 20110101

Title: Androgen receptor signaling in prostate cancer development and progression.

Journal: Journal of carcinogenesis 20110101

Title: ZMIZ1 preferably enhances the transcriptional activity of androgen receptor with short polyglutamine tract.

Journal: PloS one 20110101

Title: Metal fatigue causing cystoscope rupture during bladder neck incision.

Journal: JSLS : Journal of the Society of Laparoendoscopic Surgeons 20110101

Title: Resistance to cancer treatment: the role of somatic genetic events and the challenges for targeted therapies.

Journal: Frontiers in pharmacology 20110101

Title: Self-renewing Pten-/- TP53-/- protospheres produce metastatic adenocarcinoma cell lines with multipotent progenitor activity.

Journal: PloS one 20110101

Title: Androgen receptor antagonists and anti-prostate cancer activities of some synthesized steroidal candidates.

Journal: Chemical & pharmaceutical bulletin 20110101

Title: Metabolic complications and increased cardiovascular risks as a result of androgen deprivation therapy in men with prostate cancer.

Journal: Prostate cancer 20110101

Title: An update on the changing indications for androgen deprivation therapy for prostate cancer.

Journal: Prostate cancer 20110101

Title: Contemporary radical prostatectomy.

Journal: Prostate cancer 20110101

Title: Role of signaling transduction pathways in development of castration-resistant prostate cancer.

Journal: Prostate cancer 20110101

Title: New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer.

Journal: Prostate cancer 20110101

Title: Down-regulation of DcR2 sensitizes androgen-dependent prostate cancer LNCaP cells to TRAIL-induced apoptosis.

Journal: Cancer cell international 20110101

Title: Novel therapeutic strategies for malignant salivary gland tumors: lessons learned from breast cancer.

Journal: International journal of otolaryngology 20110101

Title: New insights into the role of androgen and oestrogen receptors in molecular apocrine breast tumours.

Journal: Breast cancer research : BCR 20110101

Title: Epigenetics in prostate cancer.

Journal: Prostate cancer 20110101

Title: The state of research into children with cancer across Europe: new policies for a new decade.

Journal: Ecancermedicalscience 20110101

Title: Efficacy and safety of gonadotropin-releasing hormone agonists used in the treatment of prostate cancer.

Journal: Drug, healthcare and patient safety 20110101

Title: XMRV Discovery and Prostate Cancer-Related Research.

Journal: Advances in virology 20110101

Title: Rare metastatic prostatic malignancy: A case report and approach to management.

Journal: Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20110101

Title: Generalized lymphadenopathy: unusual presentation of prostate adenocarcinoma.

Journal: Case reports in urology 20110101

Title: Molecular targets for radiation oncology in prostate cancer.

Journal: Frontiers in oncology 20110101

Title: [Impact of neoadjuvant hormonal therapy on the permanent ¹²⁵I-seed brachytherapy for localized high-risk prostate cancer].

Journal: Zhonghua yi xue za zhi 20101228

Title: Preferential induction of G1 arrest in androgen-responsive human prostate cancer cells by androgen receptor signaling antagonists DL3 and antiandrogen bicalutamide.

Journal: Cancer letters 20101208

Title: Cancer and renal insufficiency results of the BIRMA study.

Journal: British journal of cancer 20101207

Title: Interaction between AR signalling and CRKL bypasses casodex inhibition in prostate cancer.

Journal: Cellular signalling 20101201

Title: Relative bioavailability and tolerability of two formulations of bicalutamide 50-mg tablets: a randomized-sequence, open-label, two-period crossover study in healthy Korean male subjects.

Journal: Clinical therapeutics 20101201

Title: Trilostane, an inhibitor of 3β-hydroxysteroid dehydrogenase, has an agonistic activity on androgen receptor in human prostate cancer cells.

Journal: Cancer letters 20101128

Title: Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines.

Journal: Human molecular genetics 20101115

Title: An interdomain interaction of the androgen receptor is required for its aggregation and toxicity in spinal and bulbar muscular atrophy.

Journal: The Journal of biological chemistry 20101112

Title: Salvage therapy with bicalutamide 150 mg in nonmetastatic castration-resistant prostate cancer.

Journal: Urology 20101101

Title: Alternative antiandrogen therapy in patients with castration-resistant prostate cancer: a single-center experience.

Journal: International journal of urology : official journal of the Japanese Urological Association 20101101

Title: No long-term effects of hormonal therapy preceding brachytherapy on urinary function and health-related quality of life among prostate cancer patients.

Journal: Urology 20101101

Title: The antiandrogen bicalutamide activates the androgen receptor (AR) with a mutation in codon 741 through the mitogen activated protein kinase (MARK) pathway in human prostate cancer PC3 cells.

Journal: Oncology reports 20101101

Title: Developments in nonsteroidal antiandrogens targeting the androgen receptor.

Journal: ChemMedChem 20101004

Title: Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men.

Journal: American journal of physiology. Endocrinology and metabolism 20101001

Title: Inter-related in vitro effects of androgens, fatty acids and oxidative stress in prostate cancer: a mechanistic model supporting prevention strategies.

Journal: International journal of oncology 20101001

Title: Testosterone-induced hypertrophy of L6 myoblasts is dependent upon Erk and mTOR.

Journal: Biochemical and biophysical research communications 20101001

Title: Androgen receptor-mTOR crosstalk is regulated by testosterone availability: implication for prostate cancer cell survival.

Journal: Anticancer research 20101001

Title: Bicalutamide plus anastrozole for the treatment of gonadotropin-independent precocious puberty in boys with testotoxicosis: a phase II, open-label pilot study (BATT).

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20101001

Title: Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR.

Journal: British journal of cancer 20100928

Title: A prospective phase III randomized trial of hypofractionation versus conventional fractionation in patients with high-risk prostate cancer.

Journal: International journal of radiation oncology, biology, physics 20100901

Title: Estrogen receptor beta2 and beta5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion.

Journal: Endocrine-related cancer 20100901

Title: The androgen derivative 5alpha-androstane-3beta,17beta-diol inhibits tumor necrosis factor alpha and lipopolysaccharide induced inflammatory response in human endothelial cells and in mice aorta.

Journal: Atherosclerosis 20100901

Title: Activity of antiandrogens against juvenile and adult Schistosoma mansoni in mice.

Journal: The Journal of antimicrobial chemotherapy 20100901

Title: Detection of androgen receptor mutations in circulating tumor cells in castration-resistant prostate cancer.

Journal: Clinical chemistry 20100901

Title: Efficacy of maximal androgen blockade versus castration alone in the treatment of advanced prostate cancer: a retrospective clinical experience from a Chinese medical centre.

Journal: Asian journal of andrology 20100901

Title: Bicalutamide and third-generation aromatase inhibitors in testotoxicosis.

Journal: Pediatrics 20100901

Title: Stuttering priapism: case report and bibliographic review.

Journal: Archivos espanoles de urologia 20100901

Title: Androgens modulate autophagy and cell death via regulation of the endoplasmic reticulum chaperone glucose-regulated protein 78/BiP in prostate cancer cells.

Journal: Cell death & disease 20100901

Title: Reciprocal regulation of ZEB1 and AR in triple negative breast cancer cells.

Journal: Breast cancer research and treatment 20100801

Title: 5-Azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors.

Journal: The Prostate 20100801

Title: AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model.

Journal: Journal of cellular biochemistry 20100801

Title: Is prophylactic breast radiotherapy necessary in all patients with prostate cancer and gynecomastia and/or breast pain?

Journal: The Journal of urology 20100801

Title: A water-soluble parthenolide analogue suppresses in vivo prostate cancer growth by targeting NFkappaB and generating reactive oxygen species.

Journal: The Prostate 20100701

Title: Outcome of patients with localized prostate cancer treated by radiotherapy after confirming the absence of lymph node invasion.

Journal: Japanese journal of clinical oncology 20100701

Title: Androgen blockade for the treatment of high-flow priapism.

Journal: The journal of sexual medicine 20100701

Title: Telomerase as an important target of androgen signaling blockade for prostate cancer treatment.

Journal: Molecular cancer therapeutics 20100701

Title: Management of thrombotic thrombocytopenic purpura in metastatic prostate cancer with only endocrine therapy.

Journal: Annals of the Academy of Medicine, Singapore 20100701

Title: Comparative study of new shell-type, sub-2 micron fully porous and monolith stationary phases, focusing on mass-transfer resistance.

Journal: Journal of chromatography. A 20100604

Title: Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity.

Journal: The Prostate 20100515

Title: Risk of thromboembolic diseases in men with prostate cancer: results from the population-based PCBaSe Sweden.

Journal: The Lancet. Oncology 20100511

Title: Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells.

Journal: Breast cancer research and treatment 20100501

Title: Downmodulation of Bcl-2 sensitizes metastatic LNCaP-LN3 cells to undergo apoptosis via the intrinsic pathway.

Journal: The Prostate 20100501

Title: Relationship between bone mineral density and androgen-deprivation therapy in Japanese prostate cancer patients.

Journal: Urology 20100501

Title: Editorial comment.

Journal: Urology 20100501

Title: Improved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles.

Journal: Journal of computer-aided molecular design 20100501

Title: Androgen receptor interacts with telomeric proteins in prostate cancer cells.

Journal: The Journal of biological chemistry 20100402

Title: Establishment and characterization of an androgen receptor-dependent, androgen-independent human prostate cancer cell line, LNCaP-CS10.

Journal: The Prostate 20100401

Title: Frequency of zoledronic acid to prevent further bone loss in osteoporotic patients undergoing androgen deprivation therapy for prostate cancer.

Journal: BJU international 20100401

Title: Torsades de Pointes induced by a combination of garenoxacin and disopyramide and other cytochrome P450, family 3, subfamily A polypeptide-4-influencing drugs during hypokalemia due to licorice.

Journal: Clinical and experimental nephrology 20100401

Title: Dihydrotestosterone alters cyclooxygenase-2 levels in human coronary artery smooth muscle cells.

Journal: American journal of physiology. Endocrinology and metabolism 20100401

Title: 1{alpha},25-Dihydroxyvitamin D3 inhibits growth of VCaP prostate cancer cells despite inducing the growth-promoting TMPRSS2:ERG gene fusion.

Journal: Endocrinology 20100401

Title: Adrenal androgen levels as predictors of outcome in castration-resistant prostate cancer patients treated with combined androgen blockade using flutamide as a second-line anti-androgen.

Journal: International journal of urology : official journal of the Japanese Urological Association 20100401

Title: Antiandrogen monotherapy in patients with localized or locally advanced prostate cancer: final results from the bicalutamide Early Prostate Cancer programme at a median follow-up of 9.7 years.

Journal: BJU international 20100401

Title: Androgens induce oxidative stress and radiation resistance in prostate cancer cells though NADPH oxidase.

Journal: Prostate cancer and prostatic diseases 20100301

Title: Subjective and objective measures of late genitourinary morbidity following hypofractionated radiotherapy in men with prostate cancer.

Journal: Prostate cancer and prostatic diseases 20100301

Title: Physicochemical characterization of hot melt extruded bicalutamide-polyvinylpyrrolidone solid dispersions.

Journal: Journal of pharmaceutical sciences 20100301

Title: Antagonistic interaction between bicalutamide (Casodex) and radiation in androgen-positive prostate cancer LNCaP cells.

Journal: The Prostate 20100301

Title: Dehydroepiandrosterone-induced proliferation of prostatic epithelial cell is mediated by NFKB via PI3K/AKT signaling pathway.

Journal: The Journal of endocrinology 20100301

Title: Self-assembling methoxypoly(ethylene glycol)-b-poly(carbonate-co-L-lactide) block copolymers for drug delivery.

Journal: Biomaterials 20100301

Title: REDD1 is a major target of testosterone action in preventing dexamethasone-induced muscle loss.

Journal: Endocrinology 20100301

Title: The pure anti-androgen bicalutamide inhibits cyclin A expression both in androgen-dependent and -independent cell lines.

Journal: International journal of oncology 20100301

Title: [Bicalutamide].

Journal: Revue de l'infirmiere 20100301

Title: Laparo-endoscopic single site (LESS) robotic radical prostatectomy in an Asian man with prostate cancer: an initial case report.

Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100301

Title: Antiandrogen withdrawal syndrome and alternative antiandrogen therapy associated with the W741C mutant androgen receptor in a novel prostate cancer xenograft.

Journal: The Prostate 20100215

Title: Systematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H.

Journal: The Journal of biological chemistry 20100212

Title: An open, randomised, multicentre, phase 3 trial comparing the efficacy of two tamoxifen schedules in preventing gynaecomastia induced by bicalutamide monotherapy in prostate cancer patients.

Journal: European urology 20100201

Title: Metastasis of genitourinary tumors to the head and neck region.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20100201

Title: A randomized controlled trial of add-back estrogen or placebo on cognition in men with prostate cancer receiving an antiandrogen and a gonadotropin-releasing hormone analog.

Journal: Psychoneuroendocrinology 20100201

Title: Enhanced antiproliferative and proapoptotic effects on prostate cancer cells by simultaneously inhibiting androgen receptor and cAMP-dependent protein kinase A.

Journal: International journal of cancer 20100201

Title: Induction of bicalutamide sensitivity in prostate cancer cells by an epigenetic Puralpha-mediated decrease in androgen receptor levels.

Journal: The Prostate 20100201

Title: Metastatic prostatic adenocarcinoma mimicking inflammatory breast carcinoma: a case report.

Journal: Clinical breast cancer 20100201

Title: Capsaicin may slow PSA doubling time: case report and literature review.

Journal: Canadian Urological Association journal = Journal de l'Association des urologues du Canada 20100201

Title: Consolidation strategies in ovarian cancer: observations for future clinical trials.

Journal: Gynecologic oncology 20100101

Title: Kinetic modeling of hyperpolarized 13C1-pyruvate metabolism in normal rats and TRAMP mice.

Journal: Journal of magnetic resonance (San Diego, Calif. : 1997) 20100101

Title: Changes in neuronal activation patterns in response to androgen deprivation therapy: a pilot study.

Journal: BMC cancer 20100101

Title: Growth inhibition of androgen-responsive prostate cancer cells with brefeldin A targeting cell cycle and androgen receptor.

Journal: Journal of biomedical science 20100101

Title: A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899.

Journal: Journal of translational medicine 20100101

Title: PI3K-AKT-mTOR pathway is dominant over androgen receptor signaling in prostate cancer cells.

Journal: Cellular oncology : the official journal of the International Society for Cellular Oncology 20100101

Title: Metastatic prostate cancer in an asymptomatic patient with an initial prostate-specific antigen (PSA) serum concentration of 21,380 ng/ml.

Journal: Onkologie 20100101

Title: Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors.

Journal: Urologia internationalis 20100101

Title: Wnt-11 promotes neuroendocrine-like differentiation, survival and migration of prostate cancer cells.

Journal: Molecular cancer 20100101

Title: Effects of clusterin over-expression on metastatic progression and therapy in breast cancer.

Journal: BMC cancer 20100101

Title: What the hyena's laugh tells: sex, age, dominance and individual signature in the giggling call of Crocuta crocuta.

Journal: BMC ecology 20100101

Title: Metronomic treatment with low-dose trofosfamide leads to a long-term remission in a patient with docetaxel-refractory advanced metastatic prostate cancer.

Journal: Case reports in medicine 20100101

Title: The evolutionary impact of androgen levels on prostate cancer in a multi-scale mathematical model.

Journal: Biology direct 20100101

Title: MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1alpha/HIF-1beta.

Journal: Molecular cancer 20100101

Title: Maximal androgen blockade for advanced prostate cancer.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20100101

Title: Hormonal therapy of prostate cancer.

Journal: Progress in brain research 20100101

Title: Alterations in LMTK2, MSMB and HNF1B gene expression are associated with the development of prostate cancer.

Journal: BMC cancer 20100101

Title: Update on options for treatment of metastatic castration-resistant prostate cancer.

Journal: OncoTargets and therapy 20100101

Title: Loss of androgen receptor-dependent growth suppression by prostate cancer cells can occur independently from acquiring oncogenic addiction to androgen receptor signaling.

Journal: PloS one 20100101

Title: Alternative strategies for the treatment of classical congenital adrenal hyperplasia: pitfalls and promises.

Journal: International journal of pediatric endocrinology 20100101

Title: Androgen-regulated expression of arginase 1, arginase 2 and interleukin-8 in human prostate cancer.

Journal: PloS one 20100101

Title: Harnessing naturally occurring tumor immunity: a clinical vaccine trial in prostate cancer.

Journal: PloS one 20100101

Title: Normalization of prostate specific antigen in patients treated with intensity modulated radiotherapy for clinically localized prostate cancer.

Journal: Radiation oncology (London, England) 20100101

Title: Hormone refractory carcinoma prostate with peritoneal metastases and malignant ascites without skeletal involvement: A case report and review of literature.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20100101

Title: Treatment options for patients with triple-negative breast cancer.

Journal: Journal of hematology & oncology 20100101

Title: Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation.

Journal: Molecular cancer 20100101

Title: Impact of hormonal treatment duration in combination with radiotherapy for locally advanced prostate cancer: meta-analysis of randomized trials.

Journal: BMC cancer 20100101

Title: Evaluation of degarelix in the management of prostate cancer.

Journal: Cancer management and research 20100101

Title: Radiotherapy combined with hormonal therapy in prostate cancer: the state of the art.

Journal: Cancer management and research 20100101

Title: The effect of concurrent androgen deprivation and 3D conformal radiotherapy on prostate volume and clinical organ doses during treatment for prostate cancer.

Journal: The British journal of radiology 20091201

Title: Comparative pharmacokinetic evaluation of two formulations of bicalutamide 50-mg tablets: an open-label, randomized-sequence, single-dose, two-period crossover study in healthy Korean male volunteers.

Journal: Clinical therapeutics 20091201

Title: Fasting and cancer treatment in humans: A case series report.

Journal: Aging 20091201

Title: Treatment of familial male-limited precocious puberty (testotoxicosis) with anastrozole and bicalutamide in a boy with a novel mutation in the luteinizing hormone receptor.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20091201

Title: Disseminated intravascular coagulation secondary to metastatic prostate cancer: case report and review of the literature.

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20091201

Title: Enhanced sensitivity to androgen withdrawal due to overexpression of interleukin-6 in androgen-dependent human prostate cancer LNCaP cells.

Journal: British journal of cancer 20091117

Title: Development of carcinoid tumour in hormonally treated adenocarcinoma of the prostate.

Journal: European urology 20091101

Title: A novel androgen-dependent prostate cancer xenograft model derived from skin metastasis of a Japanese patient.

Journal: The Prostate 20091101

Title: Epigenetic modulation of PTEN expression during antiandrogenic therapies in human prostate cancer.

Journal: International journal of oncology 20091101

Title: Beyond castration and chemotherapy: novel approaches to targeting androgen-driven pathways.

Journal: Maturitas 20091020

Title: A 16-year clinical experience with intermittent androgen deprivation for prostate cancer: oncological results.

Journal: World journal of urology 20091001

Title: Effects of EGFR tyrosine kinase inhibitor erlotinib in prostate cancer cells in vitro.

Journal: The Prostate 20091001

Title: Pathological effects of prostate cancer correlate with neuroendocrine differentiation and PTEN expression after bicalutamide monotherapy.

Journal: The Journal of urology 20091001

Title: Dutasteride and bicalutamide in patients with hormone-refractory prostate cancer: the Therapy Assessed by Rising PSA (TARP) study rationale and design.

Journal: The Canadian journal of urology 20091001

Title: Radiation dose predicts for biochemical control in intermediate-risk prostate cancer patients treated with low-dose-rate brachytherapy.

Journal: International journal of radiation oncology, biology, physics 20090901

Title: Long-term changes in bone mineral density and predicted fracture risk in patients receiving androgen-deprivation therapy for prostate cancer, with stratification of treatment based on presenting values.

Journal: BJU international 20090901

Title: Characterization of choline uptake in prostate cancer cells following bicalutamide and docetaxel treatment.

Journal: European journal of nuclear medicine and molecular imaging 20090901

Title: Micellar delivery of bicalutamide and embelin for treating prostate cancer.

Journal: Pharmaceutical research 20090901

Title: Discovery of BMS-641988, a novel and potent inhibitor of androgen receptor signaling for the treatment of prostate cancer.

Journal: Cancer research 20090815

Title: Androgen-related expression of G-proteins in ovarian cancer.

Journal: British journal of cancer 20090804

Title: Bicalutamide demonstrates biologic effectiveness in prostate cancer cell lines and tumor primary cultures irrespective of Her2/neu expression levels.

Journal: Urology 20090801

Title: Ubiquitous mitochondrial creatine kinase is overexpressed in the conditioned medium and the extract of LNCaP lineaged androgen independent cell lines and facilitates prostate cancer progression.

Journal: The Prostate 20090801

Title: Twenty years of controversy surrounding combined androgen blockade for advanced prostate cancer.

Journal: Cancer 20090801

Title: Combined androgen blockade with bicalutamide for advanced prostate cancer: long-term follow-up of a phase 3, double-blind, randomized study for survival.

Journal: Cancer 20090801

Title: Androgen deprivation therapy regulation of beta1C integrin expression in prostate cancer.

Journal: Oncology reports 20090801

Title: [Androgens stimulate the expression of SOCS-3 and inhibits their effect on proliferation and secretion].

Journal: Aktuelle Urologie 20090801

Title: Starving the addiction: new opportunities for durable suppression of AR signaling in prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20090801

Title: Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity.

Journal: Toxicology and applied pharmacology 20090715

Title: High-intensity-focused ultrasound in the treatment of primary prostate cancer: the first UK series.

Journal: British journal of cancer 20090707

Title: Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts.

Journal: The Journal of steroid biochemistry and molecular biology 20090701

Title: Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit.

Journal: Journal of medicinal chemistry 20090625

Title: Alternative inhibition of androgen receptor signaling: peptidomimetic pyrimidines as direct androgen receptor/coactivator disruptors.

Journal: ACS chemical biology 20090619

Title: High performance liquid chromatography method for the pharmacokinetic study of bicalutamide SMEDDS and suspension formulations after oral administration to rats.

Journal: Talanta 20090615

Title: Duration of androgen suppression in the treatment of prostate cancer.

Journal: The New England journal of medicine 20090611

Title: Structure determination of chiral sulfoxide in diastereomeric bicalutamide derivatives.

Journal: Chirality 20090601

Title: WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics.

Journal: Cell research 20090601

Title: Integrating statistical predictions and experimental verifications for enhancing protein-chemical interaction predictions in virtual screening.

Journal: PLoS computational biology 20090601

Title: Precocious puberty and normal variant puberty: definition, etiology, diagnosis and current management.

Journal: Journal of clinical research in pediatric endocrinology 20090601

Title: Prostate-specific antigen progression predicts overall survival in patients with metastatic prostate cancer: data from Southwest Oncology Group Trials 9346 (Intergroup Study 0162) and 9916.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090520

Title: Heterogeneous nuclear ribonucleoprotein K: altered pattern of expression associated with diagnosis and prognosis of prostate cancer.

Journal: British journal of cancer 20090519

Title: Nevirapine restores androgen signaling in hormone-refractory human prostate carcinoma cells both in vitro and in vivo.

Journal: The Prostate 20090515

Title: Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy.

Journal: Cancer research 20090515

Title: Microarray coupled to quantitative RT-PCR analysis of androgen-regulated genes in human LNCaP prostate cancer cells.

Journal: Oncogene 20090514

Title: Development of a second-generation antiandrogen for treatment of advanced prostate cancer.

Journal: Science (New York, N.Y.) 20090508

Title: Anti-androgen receptor signaling and prostate cancer inhibitory effects of sucrose- and benzophenone-compounds.

Journal: Pharmaceutical research 20090501

Title: Suppression of mutant androgen receptors by flutamide.

Journal: International journal of urology : official journal of the Japanese Urological Association 20090501

Title: Functional AR signaling is evident in an in vitro mouse follicle culture bioassay that encompasses most stages of folliculogenesis.

Journal: Biology of reproduction 20090401

Title: Genome-wide impact of androgen receptor trapped clone-27 loss on androgen-regulated transcription in prostate cancer cells.

Journal: Cancer research 20090401

Title: Phase I-II trial of weekly bicalutamide in men with elevated prostate-specific antigen and negative prostate biopsies.

Journal: Cancer prevention research (Philadelphia, Pa.) 20090401

Title: Variations in blood ghrelin levels in prostate cancer patients submitted to hormone suppressive treatment.

Journal: Anticancer research 20090401

Title: [Clinical usefulness of chlormadinone acetate as an alternative antiandrogen therapy for prostate cancer relapse after combined androgen blockade therapy].

Journal: Hinyokika kiyo. Acta urologica Japonica 20090401

Title: Nanosized bicalutamide and its molecular structure in solvents.

Journal: International journal of pharmaceutics 20090331

Title: CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer.

Journal: British journal of cancer 20090310

Title: Interleukin-6 stimulation of growth of prostate cancer in vitro and in vivo through activation of the androgen receptor.

Journal: Endocrine-related cancer 20090301

Title: Hot flashes during androgen deprivation therapy with luteinizing hormone-releasing hormone agonist combined with steroidal or nonsteroidal antiandrogen for prostate cancer.

Journal: Urology 20090301

Title: Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer.

Journal: Anti-cancer drugs 20090301

Title: Inhibition of androgen receptor transcriptional activity as a novel mechanism of action of arsenic.

Journal: Molecular endocrinology (Baltimore, Md.) 20090301

Title: Interleukin-6 increases prostate cancer cells resistance to bicalutamide via TIF2.

Journal: Molecular cancer therapeutics 20090301

Title: Inappropriate treatment of prostate cancer caused by heterophilic antibody interference.

Journal: Nature clinical practice. Urology 20090301

Title: Profound bicalutamide withdrawal syndrome in a hormone-refractory T4N1 prostate cancer permitting both salvage radiotherapy and cessation of hormonal therapy.

Journal: International journal of urology : official journal of the Japanese Urological Association 20090301

Title: [Unreliable survival analysis].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20090226

Title: [Incorrect about hormone treatment in prostatic cancer].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20090226

Title: Mechanistic studies on the synthesis of bicalutamide.

Journal: Organic & biomolecular chemistry 20090221

Title: Individual variations of serum testosterone in patients with prostate cancer receiving androgen deprivation therapy.

Journal: BJU international 20090201

Title: Human xenograft models as useful tools to assess the potential of novel therapeutics in prostate cancer.

Journal: British journal of cancer 20090113

Title: Capsaicin, a component of red peppers, induces expression of androgen receptor via PI3K and MAPK pathways in prostate LNCaP cells.

Journal: FEBS letters 20090105

Title: Differential mechanisms of bicalutamide-induced apoptosis in prostate cell lines.

Journal: Prostate cancer and prostatic diseases 20090101

Title: Partial androgen suppression consequent to increased secretion of adrenal androgens in a patient with prostate cancer treated with long-acting GnRH agonists.

Journal: Prostate cancer and prostatic diseases 20090101

Title: A dynamic kinetic asymmetric transformation in the alpha-hydroxylation of racemic malonates and its application to biologically active molecules.

Journal: Angewandte Chemie (International ed. in English) 20090101

Title: Effect of androgen suppression compared with androgen receptor blockade on arterial stiffness in men with prostate cancer.

Journal: Journal of andrology 20090101

Title: Role of maximum androgen blockade in advanced prostate cancer.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20090101

Title: Degarelix and its therapeutic potential in the treatment of prostate cancer.

Journal: Clinical interventions in aging 20090101

Title: The psychometric validation of a US English satisfaction measure for patients with benign prostatic hyperplasia and lower urinary tract symptoms.

Journal: Health and quality of life outcomes 20090101

Title: Combination therapy with dutasteride and tamsulosin for the treatment of symptomatic enlarged prostate.

Journal: Clinical interventions in aging 20090101

Title: Adverse effects of androgen deprivation therapy in prostate cancer: Current management issues.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20090101

Title: Small-cell prostate carcinoma: A retrospective analysis of five newly reported cases.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20090101

Title: Modeling of alpha/beta for late rectal toxicity from a randomized phase II study: conventional versus hypofractionated scheme for localized prostate cancer.

Journal: Journal of experimental & clinical cancer research : CR 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Image guided dose escalated prostate radiotherapy: still room to improve.

Journal: Radiation oncology (London, England) 20090101

Title: Sphingosine kinase-1 is central to androgen-regulated prostate cancer growth and survival.

Journal: PloS one 20090101

Title: Long-term survival and PSA control with radiation and immunotherapy for node positive prostate cancer.

Journal: Clinical & developmental immunology 20090101

Title: 68Ga-DOTATOC-PET/CT detects neuroendocrine differentiation of prostate cancer metastases.

Journal: Nuklearmedizin. Nuclear medicine 20090101

Title: Androgen deprivation therapy for prostate cancer: indications, contraindications and possible consequences.

Journal: F1000 medicine reports 20090101

Title: Bicalutamide failure in prostate cancer treatment: involvement of Multi Drug Resistance proteins.

Journal: European journal of pharmacology 20081228

Title: Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes.

Journal: Molecular and cellular endocrinology 20081216

Title: Defining the molecular action of HDAC inhibitors and synergism with androgen deprivation in ERG-positive prostate cancer.

Journal: International journal of cancer 20081215

Title: Determination of lansoprazole in human plasma by rapid resolution liquid chromatography-electrospray tandem mass spectrometry: application to a bioequivalence study on Chinese volunteers.

Journal: Journal of pharmaceutical and biomedical analysis 20081215

Title: Skip metastase on the left neck lymph nodes of the prostatic adenocarcinoma with neuroendocrine differentiation and accompanying thyroid micropapillary carcinoma.

Journal: Pathology oncology research : POR 20081201

Title: Evaluation of quality of life in patients with previously untreated advanced prostate cancer receiving maximum androgen blockade therapy or LHRHa monotherapy: a multicenter, randomized, double-blind, comparative study.

Journal: Journal of cancer research and clinical oncology 20081201

Title: Bicalutamide inhibits androgen-mediated adhesion of prostate cancer cells exposed to ionizing radiation.

Journal: The Prostate 20081201

Title: Prolonged androgen receptor loading onto chromatin and the efficient recruitment of p160 coactivators contribute to androgen-independent growth of prostate cancer cells.

Journal: The Prostate 20081201

Title: Anaemia following initiation of androgen deprivation therapy for metastatic prostate cancer: a retrospective chart review.

Journal: The aging male : the official journal of the International Society for the Study of the Aging Male 20081201

Title: Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival.

Journal: Oncogene 20081127

Title: [Hormone treatment of prostate cancer in Norway].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20081120

Title: Genistein combined polysaccharide enhances activity of docetaxel, bicalutamide and Src kinase inhibition in androgen-dependent and independent prostate cancer cell lines.

Journal: BJU international 20081101

Title: Molecular basis of agonicity and antagonicity in the androgen receptor studied by molecular dynamics simulations.

Journal: Journal of molecular graphics & modelling 20081101

Title: [Adjuvant and neoadjuvant drug therapy for prostate cancer].

Journal: Der Urologe. Ausg. A 20081101

Title: [Choroidal metastasis from clinically regressed prostate adenocarcinoma: imaging of a rare case].

Journal: Journal francais d'ophtalmologie 20081101

Title: Experimental benefits of sex hormones on vascular function and the outcome of hormone therapy in cardiovascular disease.

Journal: Current cardiology reviews 20081101

Title: Prognostic significance of disseminated tumor cells in the bone marrow of prostate cancer patients treated with neoadjuvant hormone treatment.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081020

Title: Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators.

Journal: Bioorganic & medicinal chemistry letters 20081015

Title: A novel dietary flavonoid fisetin inhibits androgen receptor signaling and tumor growth in athymic nude mice.

Journal: Cancer research 20081015

Title: Increased PAK6 expression in prostate cancer and identification of PAK6 associated proteins.

Journal: The Prostate 20081001

Title: Androgens upregulate aquaporin 9 expression in the prostate.

Journal: International journal of urology : official journal of the Japanese Urological Association 20081001

Title: Nucleation and crystal growth in supersaturated solutions of a model drug.

Journal: Journal of colloid and interface science 20080915

Title: Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer.

Journal: The Prostate 20080915

Title: Inhibition of monoamine oxidase A promotes secretory differentiation in basal prostatic epithelial cells.

Journal: Differentiation; research in biological diversity 20080901

Title: Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes.

Journal: Carcinogenesis 20080901

Title: Alternative nonsteroidal antiandrogen therapy for advanced prostate cancer that relapsed after initial maximum androgen blockade.

Journal: The Journal of urology 20080901

Title: Undetectable level of prostate specific antigen (PSA) nadir predicts PSA biochemical failure in local prostate cancer with delayed-combined androgen blockade.

Journal: Japanese journal of clinical oncology 20080901

Title: Design and synthesis of carborane-containing androgen receptor (AR) antagonist bearing a pyridine ring.

Journal: Bioorganic & medicinal chemistry 20080901

Title: Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures.

Journal: Journal of chemical information and modeling 20080901

Title: Drug-related hepatotoxicity and hepatic failure following combined androgen blockade.

Journal: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20080901

Title: Polymorph transitions of bicalutamide: a remarkable example of mechanical activation.

Journal: Journal of pharmaceutical sciences 20080801

Title: Bicalutamide-associated fulminant hepatotoxicity.

Journal: Pharmacotherapy 20080801

Title: Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer.

Journal: Molecular cancer therapeutics 20080801

Title: Development and characterization of bicalutamide-poloxamer F68 solid dispersion systems.

Journal: Die Pharmazie 20080801

Title: 4-(Anilino)pyrrole-2-carboxamides: Novel non-steroidal/non-anilide type androgen antagonists effective upon human prostate tumor LNCaP cells with mutated nuclear androgen receptor.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Hormonal regulation of beta2-adrenergic receptor level in prostate cancer.

Journal: The Prostate 20080701

Title: Cytology of metastatic prostate cancer following orchiectomy and antiandrogen therapy: a diagnostic challenge.

Journal: Diagnostic cytopathology 20080701

Title: Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity.

Journal: Cancer research 20080615

Title: [(11)C]choline uptake with PET/CT for the initial diagnosis of prostate cancer: relation to PSA levels, tumour stage and anti-androgenic therapy.

Journal: European journal of nuclear medicine and molecular imaging 20080601

Title: Antiandrogen withdrawal in castrate-refractory prostate cancer: a Southwest Oncology Group trial (SWOG 9426).

Journal: Cancer 20080601

Title: Discovery of a novel series of nonsteroidal androgen receptor modulators: 5- or 6-oxachrysen-2-ones.

Journal: Bioorganic & medicinal chemistry letters 20080601

Title: Interleukin-8 signaling promotes androgen-independent proliferation of prostate cancer cells via induction of androgen receptor expression and activation.

Journal: Carcinogenesis 20080601

Title: [Estramustine phosphate withdrawal syndrome in relapsed prostate cancer: two case reports].

Journal: Hinyokika kiyo. Acta urologica Japonica 20080601

Title: 1alpha,25-Dihydroxyvitamin D3 down-regulates expression of prostate specific membrane antigen in prostate cancer cells.

Journal: The Prostate 20080515

Title: Chronic azacitidine treatment results in differentiating effects, sensitizes against bicalutamide in androgen-independent prostate cancer cells.

Journal: The Prostate 20080515

Title: Etoricoxib and intermittent androgen deprivation therapy in patients with biochemical progression after radical prostatectomy.

Journal: Urology 20080501

Title: Discovery and biological characterization of a novel series of androgen receptor modulators.

Journal: British journal of pharmacology 20080501

Title: Androgens transduce the G alphas-mediated activation of protein kinase A in prostate cells.

Journal: Cancer research 20080501

Title: Inhibition of apoptosis in prostate cancer cells by androgens is mediated through downregulation of c-Jun N-terminal kinase activation.

Journal: Neoplasia (New York, N.Y.) 20080501

Title: Solid-state characterization and dissolution properties of bicalutamide-beta-cyclodextrin inclusion complex.

Journal: Die Pharmazie 20080401

Title: Maximal androgen blockade for advanced prostate cancer.

Journal: Best practice & research. Clinical endocrinology & metabolism 20080401

Title: Leuprorelin depot injection: patient considerations in the management of prostatic cancer.

Journal: Therapeutics and clinical risk management 20080401

Title: Synthesis and structure-activity relationships of the first ferrocenyl-aryl-hydantoin derivatives of the nonsteroidal antiandrogen nilutamide.

Journal: Journal of medicinal chemistry 20080327

Title: Randomization reveals unexpected acute leukemias in Southwest Oncology Group prostate cancer trial.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080320

Title: Identification and optimization of a novel series of [2.2.1]-oxabicyclo imide-based androgen receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20080315

Title: Complete response to the combination therapy with androgen blockade and somatostatin analogue in a patient with advanced prostate cancer: magnetic resonance imaging with 1H-spectroscopy.

Journal: European urology 20080301

Title: The effect of combined androgen blockade on bone turnover and bone mineral density in men with prostate cancer.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20080301

Title: [Androgen deprivation for advanced prostate cancer].

Journal: Der Urologe. Ausg. A 20080301

Title: The Early Prostate Cancer program: bicalutamide in nonmetastatic prostate cancer.

Journal: Expert review of anticancer therapy 20080301

Title: Expression of BNIP3 correlates with hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha and the androgen receptor in prostate cancer and is regulated directly by hypoxia but not androgens in cell lines.

Journal: The Prostate 20080215

Title: Isolation and characterization of process related impurities and degradation products of bicalutamide and development of RP-HPLC method for impurity profile study.

Journal: Journal of pharmaceutical and biomedical analysis 20080213

Title: Prospective study of depression and fatigue in men with advanced prostate cancer receiving hormone therapy.

Journal: Psycho-oncology 20080201

Title: Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells.

Journal: Molecular cancer therapeutics 20080201

Title: Adipocytokines, obesity, and insulin resistance during combined androgen blockade for prostate cancer.

Journal: Urology 20080201

Title: Herbal/hormonal dietary supplement possibly associated with prostate cancer progression.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080115

Title: Eliciting patient preferences for hormonal therapy options in the treatment of metastatic prostate cancer.

Journal: Prostate cancer and prostatic diseases 20080101

Title: Anti-androgens increase N-terminal pro-BNP levels in men with prostate cancer.

Journal: Clinical endocrinology 20080101

Title: Downregulation of thymosin beta4 expression by androgen in prostate cancer LNCaP cells.

Journal: Journal of andrology 20080101

Title: Interleukin-4 stimulates androgen-independent growth in LNCaP human prostate cancer cells.

Journal: The Prostate 20080101

Title: A case of prostatic adenocarcinoma recurrence presenting as ductal carcinoma of the prostate.

Journal: Nature clinical practice. Urology 20080101

Title: Can prophylactic breast irradiation contribute to cardiac toxicity in patients with prostate cancer receiving androgen suppressing drugs?

Journal: Radiation oncology (London, England) 20080101

Title: Synergistic effect of a novel antiandrogen, VN/124-1, and signal transduction inhibitors in prostate cancer progression to hormone independence in vitro.

Journal: Molecular cancer therapeutics 20080101

Title: The androgen receptor can signal through Wnt/beta-Catenin in prostate cancer cells as an adaptation mechanism to castration levels of androgens.

Journal: BMC cell biology 20080101

Title: Giant organ confined prostatic adenocarcinoma: a case report.

Journal: Journal of medical case reports 20080101

Title: Cancer treatment-related bone loss: a review and synthesis of the literature.

Journal: Current oncology (Toronto, Ont.) 20080101

Title: AR, the cell cycle, and prostate cancer.

Journal: Nuclear receptor signaling 20080101

Title: Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling.

Journal: Cancer cell international 20080101

Title: The intracellular and nuclear-targeted delivery of an antiandrogen drug by carrier peptides.

Journal: Biopolymers 20080101

Title: Bicalutamide alone prior to brachytherapy achieves cytoreduction that is similar to luteinizing hormone-releasing hormone analogues with less patient-reported morbidity.

Journal: Urologic oncology 20080101

Title: Fluorodeoxyglucose-positron emission tomography/computed tomography in the staging and evaluation of treatment response in a patient with Castleman's disease: a case report.

Journal: Journal of medical case reports 20080101

Title: Pro-neural transcription factors as cancer markers.

Journal: BMC medical genomics 20080101

Title: AKT regulates androgen receptor-dependent growth and PSA expression in prostate cancer.

Journal: Advances in experimental medicine and biology 20080101

Title: Adjuvant hormonal treatment - the bicalutamide early prostate cancer program.

Journal: Frontiers of radiation therapy and oncology 20080101

Title: Quantum dots-based multiplexed immunohistochemistry of protein expression in human prostate cancer cells.

Journal: European journal of histochemistry : EJH 20080101

Title: Diverse roles of androgen receptor (AR) domains in AR-mediated signaling.

Journal: Nuclear receptor signaling 20080101

Title: Androgen regulation of the androgen receptor coregulators.

Journal: BMC cancer 20080101

Title: Prostate specific antigen (PSA) may be a poor marker for progression of prostate cancer after treatment with a combination of chemo-hormonal therapies.

Journal: The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20080101

Title: Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects.

Journal: PloS one 20080101

Title: A dramatic, objective antiandrogen withdrawal response: case report and review of the literature.

Journal: Journal of hematology & oncology 20080101

Title: Selective androgen receptor modulators in preclinical and clinical development.

Journal: Nuclear receptor signaling 20080101

Title: Strategies for prostate cancer prevention: Review of the literature.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20080101

Title: Calcitriol and TO-901317 interact in human prostate cancer LNCaP cells.

Journal: Gene regulation and systems biology 20080101

Title: Spectrophotometric estimation of bicalutamide in tablets.

Journal: Indian journal of pharmaceutical sciences 20080101

Title: Induction of the SUMO-specific protease 1 transcription by the androgen receptor in prostate cancer cells.

Journal: The Journal of biological chemistry 20071228

Title: Phase II study of sequential chemotherapy with docetaxel-estramustine followed by mitoxantrone-prednisone in patients with advanced hormone-refractory prostate cancer.

Journal: British journal of cancer 20071217

Title: Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer.

Journal: Oncogene 20071206

Title: A phase II evaluation of goserelin and bicalutamide in patients with ovarian cancer in second or higher complete clinical disease remission.

Journal: Cancer 20071201

Title: Treatment of bicalutamide-induced breast events.

Journal: Expert review of anticancer therapy 20071201

Title: A feasibility study evaluating the functional diffusion map as a predictive imaging biomarker for detection of treatment response in a patient with metastatic prostate cancer to the bone.

Journal: Neoplasia (New York, N.Y.) 20071201

Title: The efficacy of neoadjuvant androgen deprivation therapy as a prostate volume reduction before brachytherapy for clinically localized prostate cancer.

Journal: Acta medica Okayama 20071201

Title: [Adjuvant hormone therapy for prostate cancer after local treatment in the context of evidence based medicine].

Journal: Der Urologe. Ausg. A 20071101

Title: Gefitinib and bicalutamide show synergistic effects in primary cultures of prostate cancer derived from androgen-dependent naive patients.

Journal: Oncology reports 20071101

Title: [Regression of a choroidal metastasis from prostate adenocarcinoma after hormonal therapy].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20071101

Title: Unique bisphenol A transcriptome in prostate cancer: novel effects on ERbeta expression that correspond to androgen receptor mutation status.

Journal: Environmental health perspectives 20071101

Title: Substituted 6-(1-pyrrolidine)quinolin-2(1H)-ones as novel selective androgen receptor modulators.

Journal: Journal of medicinal chemistry 20071018

Title: Phosphoinositide 3-kinase-independent non-genomic signals transit from the androgen receptor to Akt1 in membrane raft microdomains.

Journal: The Journal of biological chemistry 20071005

Title: Hormonal regulation of IGFBP-2 proteolysis is attenuated with progression to androgen insensitivity in the LNCaP progression model.

Journal: Journal of cellular physiology 20071001

Title: Human sperm express a functional androgen receptor: effects on PI3K/AKT pathway.

Journal: Human reproduction (Oxford, England) 20071001

Title: Redefining clinically significant castration levels in patients with prostate cancer receiving continuous androgen deprivation therapy.

Journal: The Journal of urology 20071001

Title: Current status of endocrine therapy for prostate cancer in Japan analysis of primary androgen deprivation therapy on the basis of data collected by J-CaP.

Journal: Japanese journal of clinical oncology 20071001

Title: Surgical and biologic outcomes after neoadjuvant bicalutamide treatment in prostate cancer.

Journal: Urology 20071001

Title: Androgen receptor-mediated repression of novel target genes.

Journal: The Prostate 20070915

Title: PC-1/PrLZ contributes to malignant progression in prostate cancer.

Journal: Cancer research 20070915

Title: A 90 kDa fragment of filamin A promotes Casodex-induced growth inhibition in Casodex-resistant androgen receptor positive C4-2 prostate cancer cells.

Journal: Oncogene 20070906

Title: The role of androgen in determining differentiation and regulation of androgen receptor expression in the human prostatic epithelium transient amplifying population.

Journal: Journal of cellular physiology 20070901

Title: In vitro and in vivo effects of bicalutamide on the expression of TrkA and P75 neurotrophin receptors in prostate carcinoma.

Journal: The Prostate 20070901

Title: Androgen-dependent regulation of medium and long chain fatty acids uptake in prostate cancer.

Journal: The Prostate 20070901

Title: Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents.

Journal: Acta pharmacologica Sinica 20070901

Title: Does small-cell phenotype predict the natural history of prostate cancer? A case study in disease behavior.

Journal: Nature clinical practice. Oncology 20070901

Title: Activity of androgen receptor antagonist bicalutamide in prostate cancer cells is independent of NCoR and SMRT corepressors.

Journal: Cancer research 20070901

Title: Prostate-cancer-specific survival and clinical progression-free survival in men with prostate cancer treated intermittently with testosterone-inactivating pharmaceuticals.

Journal: Urology 20070901

Title: [Solitary peritoneal carcinomatosis in prostate cancer].

Journal: Aktuelle Urologie 20070901

Title: Bicalutamide increases phospho-Akt levels through Her2 in patients with prostate cancer.

Journal: Endocrine-related cancer 20070901

Title: Expression of GnRH type II is regulated by the androgen receptor in prostate cancer.

Journal: Endocrine-related cancer 20070901

Title: Combined androgen blockade in advanced prostate cancer: looking back to move forward.

Journal: Clinical genitourinary cancer 20070901

Title: Complete remission of metastatic carcinoma of the prostate with bicalutamide withdrawal.

Journal: Clinical genitourinary cancer 20070901

Title: Quality of life evaluation by the EORTC QLQ-C30 questionnaire in patients treated with hormonal treatment in Italy. A QuABIOS group study.

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20070901

Title: Economic evaluation of different hormonal therapies for prostate cancer. Final results from the Quality of Life Antiandrogen Blockade Italian Observational Study (QuABIOS).

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20070901

Title: Design, synthesis, and in vivo SAR of a novel series of pyrazolines as potent selective androgen receptor modulators.

Journal: Journal of medicinal chemistry 20070809

Title: Ras-MEK-ERK signaling cascade regulates androgen receptor element-inducible gene transcription and DNA synthesis in prostate cancer cells.

Journal: International journal of cancer 20070801

Title: Androgen receptor or estrogen receptor-beta blockade alters DHEA-, DHT-, and E(2)-induced proliferation and PSA production in human prostate cancer cells.

Journal: The Prostate 20070801

Title: Increased resistance to trail-induced apoptosis in prostate cancer cells selected in the presence of bicalutamide.

Journal: The Prostate 20070801

Title: Words of wisdom. Re: Bicalutamide 150 mg plus standard care vs standard care alone for early prostate cancer.

Journal: European urology 20070801

Title: Bicalutamide-induced gynaecomastia: do we have the answer?

Journal: European urology 20070701

Title: Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study.

Journal: European urology 20070701

Title: Editorial comment on: Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study.

Journal: European urology 20070701

Title: Vasoactive intestinal peptide transactivates the androgen receptor through a protein kinase A-dependent extracellular signal-regulated kinase pathway in prostate cancer LNCaP cells.

Journal: Molecular pharmacology 20070701

Title: Expression of the forkhead transcription factor FOXP1 is associated both with hypoxia inducible factors (HIFs) and the androgen receptor in prostate cancer but is not directly regulated by androgens or hypoxia.

Journal: The Prostate 20070701

Title: Androgen withdrawal in patients reduces prostate cancer hypoxia: implications for disease progression and radiation response.

Journal: Cancer research 20070701

Title: A novel synthetic compound that interrupts androgen receptor signaling in human prostate cancer cells.

Journal: Molecular cancer therapeutics 20070701

Title: [Locally advanced prostate cancer: definition, prognosis and treatment].

Journal: Bulletin du cancer 20070701

Title: Labeling and identification of LNCaP cell surface proteins: a pilot study.

Journal: The Prostate 20070615

Title: Effects of steroidal and non-steroidal antiandrogens on wild-type and mutant androgen receptors.

Journal: The Prostate 20070601

Title: The liver X receptor agonist T0901317 acts as androgen receptor antagonist in human prostate cancer cells.

Journal: Biochemical and biophysical research communications 20070601

Title: Epigallocatechin-3-gallate and bicalutamide cause growth arrest and apoptosis in NRP-152 and NRP-154 prostate epithelial cells.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070601

Title: [Role of 150 mg bicalutamide in the treatment of prostate cancer: 3rd analysis of the EPC (early prostate cancer) program].

Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20070601

Title: Prostate cancer tissue is masked by bicalutamide: a case report.

Journal: European journal of medical research 20070529

Title: Non-genomic action of resveratrol on androgen and oestrogen receptors in prostate cancer: modulation of the phosphoinositide 3-kinase pathway.

Journal: British journal of cancer 20070521

Title: Reactive oxygen species mediate androgen receptor- and serum starvation-elicited downstream signaling of ADAM9 expression in human prostate cancer cells.

Journal: The Prostate 20070515

Title: Non-steroidal antiandrogens act as AF-1 agonists under conditions of high androgen-receptor expression.

Journal: The Prostate 20070501

Title: A new hormonal therapy for estrogen receptor-negative breast cancer.

Journal: World journal of surgery 20070501

Title: Cushing syndrome associated with prostatic tumor adrenocorticotropic hormone (ACTH) expression after maximal androgen blockade therapy.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070501

Title: Circumventing anti-androgen resistance by molecular design.

Journal: Journal of the American Chemical Society 20070404

Title: Bicalutamide 50 mg monotherapy in patients with isolated high-grade PIN: findings in repeat biopsies at 6 months.

Journal: Journal of clinical pathology 20070401

Title: EZH2 promotes proliferation and invasiveness of prostate cancer cells.

Journal: The Prostate 20070401

Title: RADICALS (Radiotherapy and Androgen Deprivation in Combination after Local Surgery).

Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20070401

Title: [Cost-effectiveness analysis of maximum androgen blockade for Japanese men with advanced prostate cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20070401

Title: Bicalutamide.

Journal: Prescrire international 20070401

Title: Synthesis of potent and tissue-selective androgen receptor modulators (SARMs): 2-(2,2,2)-Trifluoroethyl-benzimidazole scaffold.

Journal: Bioorganic & medicinal chemistry letters 20070315

Title: Discovery of an androgen receptor modulator pharmacophore based on 2-quinolinones.

Journal: Bioorganic & medicinal chemistry letters 20070315

Title: Novel selective androgen receptor modulators: SAR studies on 6-bisalkylamino-2-quinolinones.

Journal: Bioorganic & medicinal chemistry letters 20070315

Title: Synthesis and biological evaluation of [18F]bicalutamide, 4-[76Br]bromobicalutamide, and 4-[76Br]bromo-thiobicalutamide as non-steroidal androgens for prostate cancer imaging.

Journal: Journal of medicinal chemistry 20070308

Title: Long-term effectiveness of luteinizing hormone-releasing hormone agonist or antiandrogen monotherapy in elderly men with localized prostate cancer (T1-2): a retrospective study.

Journal: Asian journal of andrology 20070301

Title: A novel class of pyranocoumarin anti-androgen receptor signaling compounds.

Journal: Molecular cancer therapeutics 20070301

Title: Prostate-specific antigen half-life and pretreatment prostate-specific antigen: crucial predictors for prostate-specific antigen trend in delayed-combined androgen blockade therapy.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070301

Title: Effects of flutamide as a second-line agent for maximum androgen blockade of hormone refractory prostate cancer.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070301

Title: Update on the use of dutasteride in the management of benign prostatic hypertrophy.

Journal: Clinical interventions in aging 20070301

Title: 2-(2,2,2-Trifluoroethyl)-5,6-dichlorobenzimidazole derivatives as potent androgen receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20070215

Title: Prosaposin upregulates AR and PSA expression and activity in prostate cancer cells (LNCaP).

Journal: The Prostate 20070201

Title: A role for neurotensin in bicalutamide resistant prostate cancer cells.

Journal: The Prostate 20070201

Title: Clinical efficacy of alternative antiandrogen therapy in Japanese men with relapsed prostate cancer after first-line hormonal therapy.

Journal: International journal of urology : official journal of the Japanese Urological Association 20070201

Title: The role of tamoxifen in reducing bicalutamide-induced gynaecomastia and breast pain.

Journal: BJU international 20070201

Title: [Giant prostate carcinoma treated effectively with endocrine therapy: case report].

Journal: Hinyokika kiyo. Acta urologica Japonica 20070201

Title: [Gynecomastia as a complication of hormonotherapy for prostate cancer: effect of prophylactic breast irradiation].

Journal: Harefuah 20070201

Title: Cardiometabolic aspects of polycystic ovarian syndrome.

Journal: Vascular health and risk management 20070201

Title: Differential regulation of clusterin and its isoforms by androgens in prostate cells.

Journal: The Journal of biological chemistry 20070126

Title: [Hormonal treatment of cancer of the prostate: review and present status].

Journal: Deutsche medizinische Wochenschrift (1946) 20070126

Title: The androgen receptor T877A mutant recruits LXXLL and FXXLF peptides differently than wild-type androgen receptor in a time-resolved fluorescence resonance energy transfer assay.

Journal: Biochemistry 20070123

Title: Serendipitous discovery of novel imidazolopyrazole scaffold as selective androgen receptor modulators.

Journal: Bioorganic & medicinal chemistry letters 20070115

Title: Conformational polymorphism in bicalutamide.

Journal: International journal of pharmaceutics 20070110

Title: Dual androgen-response elements mediate androgen regulation of MMP-2 expression in prostate cancer cells.

Journal: Asian journal of andrology 20070101

Title: A selective androgen receptor modulator that reduces prostate tumor size and prevents orchidectomy-induced bone loss in rats.

Journal: The Journal of steroid biochemistry and molecular biology 20070101

Title: The discovery of a potent orally efficacious indole androgen receptor antagonist through in vivo screening.

Journal: Bioorganic & medicinal chemistry letters 20070101

Title: Bicalutamide (Casodex) 150 mg plus standard care in early non-metastatic prostate cancer: results from Early Prostate Cancer Trial 24 at a median 7 years' follow-up.

Journal: Prostate cancer and prostatic diseases 20070101

Title: Evaluation of an in vitro model of androgen ablation and identification of the androgen responsive proteome in LNCaP cells.

Journal: Proteomics 20070101

Title: Bicalutamide 80 mg combined with a luteinizing hormone-releasing hormone agonist (LHRH-A) versus LHRH-A monotherapy in advanced prostate cancer: findings from a phase III randomized, double-blind, multicenter trial in Japanese patients.

Journal: Prostate cancer and prostatic diseases 20070101

Title: Suberoylanilide hydroxamic acid (vorinostat) represses androgen receptor expression and acts synergistically with an androgen receptor antagonist to inhibit prostate cancer cell proliferation.

Journal: Molecular cancer therapeutics 20070101

Title: Global update on defining and treating high-risk localized prostate cancer with leuprorelin: a Japanese perspective--the effect of primary androgen deprivation therapy on stage C prostate cancer.

Journal: BJU international 20070101

Title: Spotlight on bicalutamide 150mg in the treatment of locally advanced prostate cancer.

Journal: Drugs & aging 20070101

Title: A phase II trial of docetaxel and erlotinib as first-line therapy for elderly patients with androgen-independent prostate cancer.

Journal: BMC cancer 20070101

Title: Can a single model explain both breast cancer and prostate cancer?

Journal: Theoretical biology & medical modelling 20070101

Title: Neuroendocrine differentiation of localized prostate cancer during endocrine therapy.

Journal: Scandinavian journal of urology and nephrology 20070101

Title: The practice of Scottish urologists in the assessment and management of fracture risk in the ageing male being treated for prostate cancer.

Journal: TheScientificWorldJournal 20070101

Title: SIRNA-directed in vivo silencing of androgen receptor inhibits the growth of castration-resistant prostate carcinomas.

Journal: PloS one 20070101

Title: The coregulator Alien.

Journal: Nuclear receptor signaling 20070101

Title: Pathogenesis of prostate cancer and hormone refractory prostate cancer.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20070101

Title: Treatment algorithm in hormone-resistant prostate cancer: Practical guidelines.

Journal: Indian journal of urology : IJU : journal of the Urological Society of India 20070101

Title: Cancer-specific mortality after radiation therapy with short-course hormonal therapy or radical prostatectomy in men with localized, intermediate-risk to high-risk prostate cancer.

Journal: Cancer 20061201

Title: Docetaxel, estramustine, and 15-month androgen deprivation for men with prostate-specific antigen progression after definitive local therapy for prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061201

Title: A randomized phase III study of neoadjuvant hormonal therapy in patients with localized prostate cancer.

Journal: Clinical genitourinary cancer 20061201

Title: [Difficult clinical cases in prostate cancer: multidisciplinary staff, the rational principles of adjuvant therapy and other therapeutic options].

Journal: Annales d'urologie 20061201

Title: [Early prostate cancer 2005. New 2005 data].

Journal: Annales d'urologie 20061201

Title: [Management of gynecomastia induced by bicalutamide].

Journal: Annales d'urologie 20061201

Title: [The treatments of localized prostate cancer: the impact on sexuality].

Journal: Annales d'urologie 20061201

Title: Role of 5 alpha-reductase inhibitors in the management of prostate cancer.

Journal: Clinical interventions in aging 20061201

Title: A bioisosteric approach to the discovery of indole carbinol androgen receptor ligands.

Journal: Bioorganic & medicinal chemistry letters 20061101

Title: Transgenic mouse model for rapid pharmacodynamic evaluation of antiandrogens.

Journal: Cancer research 20061101

Title: Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer.

Journal: Cancer research 20061101

Title: [Prostate small cell carcinoma: report of two cases that differed in treatment responsiveness].

Journal: Hinyokika kiyo. Acta urologica Japonica 20061101

Title: Crosstalk between EGFR and extranuclear steroid receptors.

Journal: Annals of the New York Academy of Sciences 20061101

Title: Improving the outcome of patients with castration-resistant prostate cancer through rational drug development.

Journal: British journal of cancer 20061009

Title: Androgen induction of prostate cancer cell invasion is mediated by ezrin.

Journal: The Journal of biological chemistry 20061006

Title: Expression and function of lysophosphatidic acid LPA1 receptor in prostate cancer cells.

Journal: Endocrinology 20061001

Title: Arylisothiocyanato selective androgen receptor modulators (SARMs) for prostate cancer.

Journal: Bioorganic & medicinal chemistry 20061001

Title: Androgen receptor regulates nuclear trafficking and nuclear domain residency of corepressor HDAC7 in a ligand-dependent fashion.

Journal: Experimental cell research 20061001

Title: Restoring chemotherapy and hormone therapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model.

Journal: The Prostate 20061001

Title: [Local recurrence of prostate cancer: hormone therapy].

Journal: Der Urologe. Ausg. A 20061001

Title: An improved and validated LC method for resolution of bicalutamide enantiomers using amylose tris-(3,5-dimethylphenylcarbamate) as a chiral stationary phase.

Journal: Journal of pharmaceutical and biomedical analysis 20060926

Title: Ligand-independent androgen receptor activity is activation function-2-independent and resistant to antiandrogens in androgen refractory prostate cancer cells.

Journal: The Journal of biological chemistry 20060922

Title: Tolerability, efficacy and pharmacokinetics of bicalutamide 300 mg, 450 mg or 600 mg as monotherapy for patients with locally advanced or metastatic prostate cancer, compared with castration.

Journal: BJU international 20060901

Title: Treatment of familial male-limited precocious puberty with bicalutamide and anastrozole.

Journal: The Journal of pediatrics 20060901

Title: Characteristics of bicalutamide solid dispersions and improvement of the dissolution.

Journal: Drug development and industrial pharmacy 20060901

Title: [Keyrole of endocrinology in the victory against prostate cancer].

Journal: Bulletin du cancer 20060901

Title: Pretreatment serum level of HER2/nue as a prognostic factor in metastatic prostate cancer patients about to undergo endocrine therapy.

Journal: International journal of urology : official journal of the Japanese Urological Association 20060901

Title: The hypogonadal (hpg) mouse as a model to investigate the estrogenic regulation of spermatogenesis.

Journal: Human fertility (Cambridge, England) 20060901

Title: Distinct regulation by steroids of messenger RNAs for FSHR and CYP19A1 in bovine granulosa cells.

Journal: Biology of reproduction 20060801

Title: The effect of androgen deprivation therapy on fasting serum lipid and glucose parameters.

Journal: The Journal of urology 20060801

Title: Antiandrogen treatments in locally advanced prostate cancer: are they all the same?

Journal: Journal of cancer research and clinical oncology 20060801

Title: Androgen receptor remains critical for cell-cycle progression in androgen-independent CWR22 prostate cancer cells.

Journal: The American journal of pathology 20060801

Title: Role of androgens on MCF-7 breast cancer cell growth and on the inhibitory effect of letrozole.

Journal: Cancer research 20060801

Title: What implications do the tolerability profiles of antiandrogens and other commonly used prostate cancer treatments have on patient care?

Journal: Journal of cancer research and clinical oncology 20060801

Title: The addition of bicalutamide 150 mg to radiotherapy significantly improves overall survival in men with locally advanced prostate cancer.

Journal: Journal of cancer research and clinical oncology 20060801

Title: Adjuvant bicalutamide for early prostate cancer: an update.

Journal: Nature clinical practice. Urology 20060801

Title: Hot flashes.

Journal: Clinical journal of oncology nursing 20060801

Title: Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility.

Journal: Journal of cellular biochemistry 20060701

Title: Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells.

Journal: American journal of physiology. Cell physiology 20060701

Title: Conditional expression of PTEN alters the androgen responsiveness of prostate cancer cells.

Journal: The Prostate 20060701

Title: Digitate dermatosis responding to bicalutamide therapy.

Journal: Clinical and experimental dermatology 20060701

Title: Are bone scans necessary in men with low prostate specific antigen levels following localized therapy?

Journal: The Journal of urology 20060701

Title: The bicalutamide 150 mg early prostate cancer program: findings of the North American trial at 7.7-year median followup.

Journal: The Journal of urology 20060701

Title: Prostate specific antigen expression does not necessarily correlate with prostate cancer cell growth.

Journal: The Journal of urology 20060701

Title: Pathological changes of high-grade prostatic intraepithelial neoplasia and prostate cancer after monotherapy with bicalutamide 150 mg.

Journal: BJU international 20060701

Title: Efficacy of neoadjuvant bicalutamide and dutasteride as a cytoreductive regimen before prostate brachytherapy.

Journal: Urology 20060701

Title: Preliminary results of bicalutamide monotherapy on biochemical failure of localized prostate cancer.

Journal: Journal of the National Medical Association 20060701

Title: [8-month neoadjuvant hormonal therapy before radical prostatectomy for high-risk prostate cancer].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20060701

Title: Treatment of bicalutamide-induced gynecomastia with breast-reduction surgery in prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060620

Title: Docetaxel induces apoptosis in hormone refractory prostate carcinomas during multiple treatment cycles.

Journal: British journal of cancer 20060605

Title: Functional analyses of C13orf19/P38IP in prostate cell lines.

Journal: Oncology reports 20060601

Title: Deferred combined androgen blockade therapy using bicalutamide in patients with hormone-refractory prostate cancer during androgen deprivation monotherapy.

Journal: BJU international 20060601

Title: Maximal androgen blockade for the treatment of metastatic prostate cancer--a systematic review.

Journal: Current oncology (Toronto, Ont.) 20060601

Title: DHT and testosterone, but not DHEA or E2, differentially modulate IGF-I, IGFBP-2, and IGFBP-3 in human prostatic stromal cells.

Journal: American journal of physiology. Endocrinology and metabolism 20060501

Title: Combined androgen blockade: an update.

Journal: The Urologic clinics of North America 20060501

Title: Failure of gonadotropin-releasing hormone agonists with and without sterile abscess formation at depot sites: insight into mechanisms?

Journal: Urology 20060501

Title: Differentially expressed genes in the prostate cancer cell line LNCaP after exposure to androgen and anti-androgen.

Journal: Cancer genetics and cytogenetics 20060415

Title: Spontaneous reporting of hepatotoxicity associated with antiandrogens: data from the Spanish pharmacovigilance system.

Journal: Pharmacoepidemiology and drug safety 20060401

Title: Glutamic acid 709 substitutions highlight the importance of the interaction between androgen receptor helices H3 and H12 for androgen and antiandrogen actions.

Journal: Molecular endocrinology (Baltimore, Md.) 20060401

Title: Insulin sensitivity during combined androgen blockade for prostate cancer.

Journal: The Journal of clinical endocrinology and metabolism 20060401

Title: Preclinical pharmacology of a nonsteroidal ligand for androgen receptor-mediated imaging of prostate cancer.

Journal: The Journal of pharmacology and experimental therapeutics 20060401

Title: New perspective in the management of neuroendocrine differentiation in prostate adenocarcinoma.

Journal: International journal of clinical practice 20060401

Title: Intermittent androgen deprivation therapy may prolong the duration of androgen dependence of well-differentiated prostate cancer.

Journal: Hinyokika kiyo. Acta urologica Japonica 20060401

Title: Stress kinase signaling regulates androgen receptor phosphorylation, transcription, and localization.

Journal: Molecular endocrinology (Baltimore, Md.) 20060301

Title: The androgen receptor pathway is by-passed in prostate cancer cells generated after prolonged treatment with bicalutamide.

Journal: The Prostate 20060301

Title: Apples and oranges. Re: 7.4-year update of the ongoing bicalutamide Early Prostate Cancer (EPC) trial programme.

Journal: BJU international 20060301

Title: The third analysis of the bicalutamide Early Prostate Cancer programme.

Journal: BJU international 20060301

Title: Managing locally advanced prostate cancer: a urologist's and a patient's perspective.

Journal: Anti-cancer drugs 20060301

Title: Hormonal treatment for prostate cancer in Italy. Preliminary data from a survey of the QUABIOS Group.

Journal: Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20060301

Title: [13th European Congress of Medical Oncology. Prevention of uterine cancer, adjuvant treatment of early prostate cancer and the promises of nanotechnology].

Journal: Revue medicale suisse 20060208

Title: Dihydrotestosterone decreases tumor necrosis factor-alpha and lipopolysaccharide-induced inflammatory response in human endothelial cells.

Journal: The Journal of clinical endocrinology and metabolism 20060201

Title: Bicalutamide 150 mg plus standard care vs standard care alone for early prostate cancer.

Journal: BJU international 20060201

Title: [A case of prostatic cancer discovered from lung metastatic lesions].

Journal: Hinyokika kiyo. Acta urologica Japonica 20060201

Title: (+)-(2R,5S)-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-dimethyl-N-[6-(trifluoromethyl)pyridin-3- yl]piperazine-1-carboxamide (YM580) as an orally potent and peripherally selective nonsteroidal androgen receptor antagonist.

Journal: Journal of medicinal chemistry 20060126

Title: Testosterone inhibits adipogenic differentiation in 3T3-L1 cells: nuclear translocation of androgen receptor complex with beta-catenin and T-cell factor 4 may bypass canonical Wnt signaling to down-regulate adipogenic transcription factors.

Journal: Endocrinology 20060101

Title: Side-effects of treatments for locally advanced prostate cancer.

Journal: BJU international 20060101

Title: A phase I trial of pox PSA vaccines (PROSTVAC-VF) with B7-1, ICAM-1, and LFA-3 co-stimulatory molecules (TRICOM) in patients with prostate cancer.

Journal: Journal of translational medicine 20060101

Title: Persistence of prostatic intraepithelial neoplasia after effective chemoprevention of microscopic prostate cancer with antiandrogen in a rat model.

Journal: The Journal of urology 20060101

Title: Screening for metabolically stable aryl-propionamide-derived selective androgen receptor modulators for doping control purposes.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway.

Journal: Molecular cancer 20060101

Title: [Transcriptional regulation of placental transforming growth factor-beta by calcitriol in prostate cancer cells is androgen-independent].

Journal: Molekuliarnaia biologiia 20060101

Title: Enhanced expression of heat shock protein 27 following neoadjuvant hormonal therapy is associated with poor clinical outcome in patients undergoing radical prostatectomy for prostate cancer.

Journal: Anticancer research 20060101

Title: Molecular markers and their prognostic impact in patients with advanced prostate cancer undergoing intermittent androgen suppression.

Journal: Prostate cancer and prostatic diseases 20060101

Title: Bicalutamide 150mg: a review of its use in the treatment of locally advanced prostate cancer.

Journal: Drugs 20060101

Title: Pharmacokinetics of two novel bicalutamide formulations in healthy male volunteers.

Journal: Pharmacology 20060101

Title: Influence of bicalutamide with or without tamoxifen or anastrozole on insulin-like growth factor 1 and binding proteins in prostate cancer patients.

Journal: The International journal of biological markers 20060101

Title: The limited significance of a longer duration of neoadjuvant hormonal therapy prior to radical prostatectomy for high-risk prostate cancer in Japanese men.

Journal: Urologia internationalis 20060101

Title: Failure to maintain a suppressed level of serum testosterone during long-acting depot luteinizing hormone-releasing hormone agonist therapy in patients with advanced prostate cancer.

Journal: Urologia internationalis 20060101

Title: Estrogen-receptor-alpha-positive extramammary Paget's disease treated with hormonal therapy.

Journal: Dermatology (Basel, Switzerland) 20060101

Title: Bicalutamide 150 mg in addition to standard care for patients with early non-metastatic prostate cancer: updated results from the Scandinavian Prostate Cancer Period Group-6 Study after a median follow-up period of 7.1 years.

Journal: Scandinavian journal of urology and nephrology 20060101

Title: High-performance liquid chromatographic enantioseparation of bicalutamide and its related compounds.

Journal: Journal of chromatography. A 20051209

Title: Complete androgen ablation suppresses prostate stem cell antigen (PSCA) mRNA expression in human prostate carcinoma.

Journal: The Prostate 20051201

Title: Role of androgen receptor in the progression of human prostate tumor cells to androgen independence and insensitivity.

Journal: The Prostate 20051201

Title: Secretoglobin 2A1 is under selective androgen control mediated by a peculiar binding site for Sp family transcription factors.

Journal: Molecular endocrinology (Baltimore, Md.) 20051201

Title: Risks and benefits of hormonal manipulation as monotherapy or adjuvant treatment in localised prostate cancer.

Journal: European urology 20051201

Title: Gynecomastia and breast pain induced by adjuvant therapy with bicalutamide after radical prostatectomy in patients with prostate cancer: the role of tamoxifen and radiotherapy.

Journal: The Journal of urology 20051201

Title: Co-activator and co-repressor interplay on the human androgen receptor.

Journal: Andrologia 20051201

Title: Testotoxicosis: current viewpoint.

Journal: Pediatric endocrinology reviews : PER 20051201

Title: Prostate cancer PET bioprobes: synthesis of [18F]-radiolabeled hydroxyflutamide derivatives.

Journal: Bioorganic & medicinal chemistry 20051115

Title: Structural basis for accommodation of nonsteroidal ligands in the androgen receptor.

Journal: The Journal of biological chemistry 20051111

Title: Direct agonist/antagonist functions of dehydroepiandrosterone.

Journal: Endocrinology 20051101

Title: Possible role of adaptive mutation in resistance to antiandrogen in prostate cancer cells.

Journal: The Prostate 20051101

Title: The patient's choice of androgen-deprivation therapy in locally advanced prostate cancer: bicalutamide, a gonadotrophin-releasing hormone analogue or orchidectomy.

Journal: BJU international 20051101

Title: Estrogenic induction of spermatogenesis in the hypogonadal (hpg) mouse: role of androgens.

Journal: Reproduction (Cambridge, England) 20051101

Title: Antiandrogen bicalutamide promotes tumor growth in a novel androgen-dependent prostate cancer xenograft model derived from a bicalutamide-treated patient.

Journal: Cancer research 20051101

Title: Exploratory study of drug plasma levels during bicalutamide 150 mg therapy co-administered with tamoxifen or anastrozole for prophylaxis of gynecomastia and breast pain in men with prostate cancer.

Journal: Cancer chemotherapy and pharmacology 20051001

Title: A phase II study of nilutamide in men with prostate cancer after the failure of flutamide or bicalutamide therapy.

Journal: BJU international 20051001

Title: Clinical outcome of maximum androgen blockade using flutamide as second-line hormonal therapy for hormone-refractory prostate cancer.

Journal: BJU international 20051001

Title: Prostate cancer presenting with fever and rigors.

Journal: Internal medicine journal 20051001

Title: [Usefulness and positioning of MAB therapy for prostate cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20051001

Title: Is combined androgen blockade with bicalutamide cost-effective compared with combined androgen blockade with flutamide?

Journal: Urology 20051001

Title: Insulin resistance as an adverse effect of leuprolide and bicalutamide treatment.

Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20051001

Title: Predictive factors for skeletal complications in hormone-refractory prostate cancer patients with metastatic bone disease.

Journal: British journal of cancer 20050919

Title: Antiandrogens prevent stable DNA-binding of the androgen receptor.

Journal: Journal of cell science 20050915

Title: Androgen receptor signaling and vitamin D receptor action in prostate cancer cells.

Journal: The Prostate 20050901

Title: Clinical outcome of oral uracil/tegafur (UFT) therapy for patients with hormone refractory prostate cancer.

Journal: Oncology reports 20050901

Title: Effect of androgen deprivation therapy in the thyroid function test of patients with prostate cancer.

Journal: Anti-cancer drugs 20050901

Title: Is prostate-specific antigen a valid surrogate end point for survival in hormonally treated patients with metastatic prostate cancer? Joint research of the European Organisation for Research and Treatment of Cancer, the Limburgs Universitair Centrum, and AstraZeneca Pharmaceuticals.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050901

Title: Late radiotherapy toxicity after prostate cancer treatment: influence of hormonal therapy.

Journal: Urology 20050901

Title: Radiotherapeutic prophylaxis of gynecomastia.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050820

Title: Androgen receptor regulates Cdc6 in synchronized LNCaP cells progressing from G1 to S phase.

Journal: Journal of cellular physiology 20050801

Title: Phosphorylation status of Fas-associated death domain-containing protein (FADD) is associated with prostate cancer progression.

Journal: The Journal of pathology 20050801

Title: The cost-effectiveness of combined androgen blockade with bicalutamide and luteinizing hormone releasing hormone agonist in men with metastatic prostate cancer.

Journal: The Journal of urology 20050801

Title: Additive antitumor effects of the epidermal growth factor receptor tyrosine kinase inhibitor, gefitinib (Iressa), and the nonsteroidal antiandrogen, bicalutamide (Casodex), in prostate cancer cells in vitro.

Journal: International journal of cancer 20050701

Title: Bicalutamide ('Casodex') 150 mg as adjuvant to radiotherapy in patients with localised or locally advanced prostate cancer: results from the randomised Early Prostate Cancer Programme.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050701

Title: The impact of hormone therapy on post-implant dosimetry and outcome following Iodine-125 implant monotherapy for localised prostate cancer.

Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050601

Title: An interdisciplinary approach to treating prostate cancer.

Journal: Urology 20050601

Title: Treating the biochemical recurrence of prostate cancer after definitive primary therapy.

Journal: Clinical prostate cancer 20050601

Title: Locally advanced prostate cancer treated with radiotherapy and androgen deprivation.

Journal: Nature clinical practice. Urology 20050601

Title: 5alpha-dihydrotestosterone inhibits 1alpha,25-dihydroxyvitamin D3-induced expression of CYP24 in human prostate cancer cells.

Journal: The Prostate 20050515

Title: Induction of AP-1 activity by androgen activation of the androgen receptor in LNCaP human prostate carcinoma cells.

Journal: The Prostate 20050501

Title: Biochemical recurrence after definitive prostate cancer therapy. Part II: treatment strategies for biochemical recurrence of prostate cancer.

Journal: Current opinion in urology 20050501

Title: Preventing bone loss during androgen deprivation therapy for prostate cancer: early experience with neridronate.

Journal: European urology 20050501

Title: Efficacy and tolerability of radiotherapy as treatment for bicalutamide-induced gynaecomastia and breast pain in prostate cancer.

Journal: European urology 20050501

Title: Efficacy of tamoxifen and radiotherapy for prevention and treatment of gynaecomastia and breast pain caused by bicalutamide in prostate cancer: a randomised controlled trial.

Journal: The Lancet. Oncology 20050501

Title: [Reevaluation of MAB therapy and progress of endocrine therapy].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20050501

Title: Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.

Journal: Journal of medicinal chemistry 20050421

Title: Docetaxel followed by hormone therapy in men experiencing increasing prostate-specific antigen after primary local treatments for prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050420

Title: A case of male breast cancer in association with bicalutamide-induced gynaecomastia.

Journal: Breast (Edinburgh, Scotland) 20050401

Title: N-Arylpiperazine-1-carboxamide derivatives: a novel series of orally active nonsteroidal androgen receptor antagonists.

Journal: Chemical & pharmaceutical bulletin 20050401

Title: The nongenotropic synthetic ligand 4-estren-3alpha17beta-diol is a high-affinity genotropic androgen receptor agonist.

Journal: Molecular pharmacology 20050301

Title: Reversibility of androgen deprivation therapy in patients with prostate cancer.

Journal: The Journal of urology 20050301

Title: Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells.

Journal: Cancer research 20050301

Title: Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.

Journal: Endocrine-related cancer 20050301

Title: Successful recovery from interstitial pneumonitis, induced by bicalutamide and leuprorelin acetate given as treatment for prostate cancer.

Journal: Hinyokika kiyo. Acta urologica Japonica 20050301

Title: Combined androgen blockade: the case for bicalutamide.

Journal: Clinical prostate cancer 20050301

Title: The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists.

Journal: The Journal of biological chemistry 20050225

Title: Three-dimensional structure-activity relationships of nonsteroidal ligands in complex with androgen receptor ligand-binding domain.

Journal: Journal of medicinal chemistry 20050224

Title: Phase III pilot study of dose escalation using conformal radiotherapy in prostate cancer: PSA control and side effects.

Journal: British journal of cancer 20050214

Title: Androgenic induction of growth and differentiation in the rodent uterus involves the modulation of estrogen-regulated genetic pathways.

Journal: Endocrinology 20050201

Title: Delta-4-androstene-3,17-dione binds androgen receptor, promotes myogenesis in vitro, and increases serum testosterone levels, fat-free mass, and muscle strength in hypogonadal men.

Journal: The Journal of clinical endocrinology and metabolism 20050201

Title: Evaluation of tamoxifen and anastrozole in the prevention of gynecomastia and breast pain induced by bicalutamide monotherapy of prostate cancer.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050201

Title: The role of protein kinase A pathway and cAMP responsive element-binding protein in androgen receptor-mediated transcription at the prostate-specific antigen locus.

Journal: Journal of molecular endocrinology 20050201

Title: Comparison of microvessel densities in rat prostate tissues treated with finasteride, bicalutamide and surgical castration: a preliminary study.

Journal: International journal of urology : official journal of the Japanese Urological Association 20050201

Title: Microarray analysis of bicalutamide action on telomerase activity, p53 pathway and viability of prostate carcinoma cell lines.

Journal: The Journal of pharmacy and pharmacology 20050101

Title: Stable expression of constitutively-activated STAT3 in benign prostatic epithelial cells changes their phenotype to that resembling malignant cells.

Journal: Molecular cancer 20050101

Title: Approach to management of clinically localized prostate cancer in patients with human immunodeficiency virus.

Journal: Urology 20050101

Title: [Correlation between re-biopsy one year after endocrine therapy and long-term prognosis in localized prostate cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20050101

Title: Randomized controlled trial to evaluate radiotherapy +/- endocrine therapy versus endocrine therapy alone for PSA failure after radical prostatectomy: Japan Clinical Oncology Group Study JCOG 0401.

Journal: Japanese journal of clinical oncology 20050101

Title: Prevention and management of bicalutamide-induced gynecomastia and breast pain: randomized endocrinologic and clinical studies with tamoxifen and anastrozole.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Bicalutamide vs cyproterone acetate in preventing flare with LHRH analogue therapy for prostate cancer--a pilot study.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Prolonged response to nilutamide in a patient with stage D0.5 prostate cancer who previously failed androgen deprivation therapy.

Journal: American journal of therapeutics 20050101

Title: The Estradiol-Dihydrotestosterone model of prostate cancer.

Journal: Theoretical biology & medical modelling 20050101

Title: Casodex treatment induces hypoxia-related gene expression in the LNCaP prostate cancer progression model.

Journal: BMC urology 20050101

Title: Evaluating the use of early hormonal therapy in patients with localised or locally advanced prostate cancer.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Comparative effects of bicalutamide (Casodex) versus orchidectomy on bone mineral density, bone remodelling, and bone biomechanics in healthy rats.

Journal: Urologia internationalis 20050101

Title: Bicalutamide ('Casodex') 150 mg in addition to standard care in patients with nonmetastatic prostate cancer: updated results from a randomised double-blind phase III study (median follow-up 5.1 y) in the early prostate cancer programme.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Case study: management of advanced prostate cancer with soft tissue metastases.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Case study: management of lymph node-positive disease detected at radical prostatectomy.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Impact of hormone therapy on acute radiotherapy toxicity in the treatment of prostate cancer.

Journal: Prostate cancer and prostatic diseases 20050101

Title: Behavior of free testosterone in patients with prostate cancer on androgen deprivation therapy.

Journal: The International journal of biological markers 20050101

Title: Proptosis and decreased vision secondary to prostate cancer orbital wall metastasis.

Journal: Anticancer research 20050101

Title: Diethylstilboestrol versus bicalutamide in hormone refractory prostate carcinoma: a prospective randomized trial.

Journal: Urologia internationalis 20050101

Title: 4-OH tamoxifen does not interfere with bicalutamide inhibitory effects on human prostatic cancer cells in vitro.

Journal: Anticancer research 20050101

Title: Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro.

Journal: The Journal of urology 20041201

Title: Major impact of hormonal therapy in localized prostate cancer--death can already be an exception.

Journal: The Journal of steroid biochemistry and molecular biology 20041201

Title: Coregulator recruitment and histone modifications in transcriptional regulation by the androgen receptor.

Journal: Molecular endocrinology (Baltimore, Md.) 20041101

Title: Neridronate prevents bone loss in patients receiving androgen deprivation therapy for prostate cancer.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20041101

Title: Synthesis and pharmacological evaluation of novel arylpiperazine derivatives as nonsteroidal androgen receptor antagonists.

Journal: Chemical & pharmaceutical bulletin 20041101

Title: Androgen receptor is targeted to distinct subcellular compartments in response to different therapeutic antiandrogens.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20041101

Title: Bicalutamide 150 mg in addition to standard care in patients with localized or locally advanced prostate cancer: results from the second analysis of the early prostate cancer program at median followup of 5.4 years.

Journal: The Journal of urology 20041101

Title: Bicalutamide (150 mg) versus placebo as immediate therapy alone or as adjuvant to therapy with curative intent for early nonmetastatic prostate cancer: 5.3-year median followup from the Scandinavian Prostate Cancer Group Study Number 6.

Journal: The Journal of urology 20041101

Title: Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20041001

Title: The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer.

Journal: The Journal of pathology 20041001

Title: Prophylactic breast irradiation with a single dose of electron beam radiotherapy (10 Gy) significantly reduces the incidence of bicalutamide-induced gynecomastia.

Journal: International journal of radiation oncology, biology, physics 20041001

Title: Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.

Journal: Cancer research 20041001

Title: Effects of testosterone, dihydrotestosterone, and 17beta-estradiol on human ovarian tissue survival in culture.

Journal: Fertility and sterility 20041001

Title: Bicalutamide 150 mg: practical prescribing in patients with early prostate cancer.

Journal: BJU international 20041001

Title: Unexpected response of hormone-refractory prostate cancer to treatment with an antileukemic chemotherapy regimen.

Journal: Urology 20041001

Title: Potent CYP17 inhibitors: improved syntheses, pharmacokinetics and anti-tumor activity in the LNCaP human prostate cancer model.

Journal: The Journal of steroid biochemistry and molecular biology 20041001

Title: Is there a role for chemotherapy in prostate cancer?

Journal: British journal of cancer 20040913

Title: Combination hormonal therapy: a reassessment within advanced prostate cancer.

Journal: Prostate cancer and prostatic diseases 20040901

Title: Monotherapy in advanced prostate cancer: an overview.

Journal: Experimental oncology 20040901

Title: Osteoporosis and spinal fractures in men with prostate cancer: risk factors and effects of androgen deprivation therapy.

Journal: The Journal of urology 20040801

Title: Re: The effects of combined androgen blockade on cognitive function during the first cycle of intermittent androgen suppression in patients with prostate cancer.

Journal: The Journal of urology 20040801

Title: Antiandrogens in prostate cancer endocrine therapy.

Journal: Current cancer drug targets 20040801

Title: The 3rd Conference on Asian Trends in Prostate Cancer Hormone Therapy.

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20040801

Title: Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol.

Journal: The Journal of steroid biochemistry and molecular biology 20040801

Title: A ligand-based approach to identify quantitative structure-activity relationships for the androgen receptor.

Journal: Journal of medicinal chemistry 20040715

Title: Bicalutamide monotherapy versus leuprolide monotherapy for prostate cancer: effects on bone mineral density and body composition.

Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040701

Title: Regulation of prostate-specific antigen by activin A in prostate cancer LNCaP cells.

Journal: American journal of physiology. Endocrinology and metabolism 20040601

Title: Identification and characterization of PLZF as a prostatic androgen-responsive gene.

Journal: The Prostate 20040601

Title: Bicalutamide 150 mg maintains bone mineral density during monotherapy for localized or locally advanced prostate cancer.

Journal: The Journal of urology 20040601

Title: Regulation of matrix metalloproteinase 13 expression by androgen in prostate cancer.

Journal: Oncology reports 20040601

Title: The biological basis for the use of an anti-androgen and a 5-alpha-reductase inhibitor in the treatment of recurrent prostate cancer: Case report and review.

Journal: Oncology reports 20040601

Title: Finasteride and bicalutamide as primary hormonal therapy in patients with advanced adenocarcinoma of the prostate.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20040601

Title: Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells.

Journal: Journal of molecular endocrinology 20040601

Title: Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells.

Journal: Endocrinology 20040501

Title: Re: See W, Iversen P, Wirth M, McLeod D, Garside L, Morris T. Immediate treatment with bicalutamide 150 mg as adjuvant therapy significantly reduces the risk of PSA progression in early prostatic cancer. Eur Urol 2003;44:512-8.

Journal: European urology 20040501

Title: Interlaboratory comparison of four in vitro assays for assessing androgenic and antiandrogenic activity of environmental chemicals.

Journal: Environmental health perspectives 20040501

Title: Is the efficacy of hormonal therapy affected by lymph node status? data from the bicalutamide (Casodex) Early Prostate Cancer program.

Journal: Urology 20040501

Title: The selection of hormonal therapy in prostate cancer: who, when, and for how long?

Journal: Journal of the National Comprehensive Cancer Network : JNCCN 20040501

Title: Androgen signaling is required for the vitamin D-mediated growth inhibition in human prostate cancer cells.

Journal: Oncogene 20040422

Title: Androgen receptor mediates non-genomic activation of phosphatidylinositol 3-OH kinase in androgen-sensitive epithelial cells.

Journal: The Journal of biological chemistry 20040409

Title: Dexamethasone enhances the cytotoxic effect of radioiodine therapy in prostate cancer cells expressing the sodium iodide symporter.

Journal: The Journal of clinical endocrinology and metabolism 20040301

Title: Effect of nonsteroidal antiandrogen monotherapy versus castration therapy on neuroendocrine differentiation in prostate carcinoma.

Journal: Urology 20040301

Title: An evaluation of bicalutamide in the treatment of prostate cancer.

Journal: Clinical prostate cancer 20040301

Title: p66Shc protein is upregulated by steroid hormones in hormone-sensitive cancer cells and in primary prostate carcinomas.

Journal: International journal of cancer 20040220

Title: Alternative antiandrogens to treat prostate cancer relapse after initial hormone therapy.

Journal: The Journal of urology 20040201

Title: Bicalutamide (Casodex) in the treatment of prostate cancer.

Journal: Expert review of anticancer therapy 20040201

Title: [A case of seminal vesicle cyst due to the obstruction of the ejaculatory duct: possible association with prostate cancer].

Journal: Hinyokika kiyo. Acta urologica Japonica 20040201

Title: Androgen ablation therapy for prostate carcinoma suppresses the immunoreactive telomerase subunit hTERT.

Journal: Cancer 20040115

Title: The adrenal androgen androstenediol is present in prostate cancer tissue after androgen deprivation therapy and activates mutated androgen receptor.

Journal: Cancer research 20040115

Title: Gadd45gamma is androgen-responsive and growth-inhibitory in prostate cancer cells.

Journal: Molecular and cellular endocrinology 20040115

Title: Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor.

Journal: Molecular endocrinology (Baltimore, Md.) 20040101

Title: Prognosis of stage pT0 after prolonged neoadjuvant endocrine therapy of prostate cancer: a matched-pair analysis.

Journal: European urology 20040101

Title: Estrogen and androgen receptors as comediators of breast cancer cell proliferation: providing a new therapeutic tool.

Journal: Archives of surgery (Chicago, Ill. : 1960) 20040101

Title: A new luciferase reporter gene assay for the detection of androgenic and antiandrogenic effects based on a human prostate specific antigen promoter and PC3/AR human prostate cancer cells.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040101

Title: Antiandrogen monotherapy: recommendations for the treatment of prostate cancer.

Journal: Urologia internationalis 20040101

Title: Superior anti-tumor efficacy of bicalutamide 80 mg in combination with a luteinizing hormone-releasing hormone (LHRH) agonist versus LHRH agonist monotherapy as first-line treatment for advanced prostate cancer: interim results of a randomized study in Japanese patients.

Journal: Japanese journal of clinical oncology 20040101

Title: Androgen signaling and post-transcriptional downregulation of Bcl-2 in androgen-unresponsive prostate cancer.

Journal: Prostate cancer and prostatic diseases 20040101

Title: High-dose radiotherapy plus prolonged hormone therapy in CT2-3 prostatic carcinoma: is it useful?

Journal: Tumori 20040101

Title: Cost-effectiveness analysis of bicalutamide (Casodex) for adjuvant treatment of early prostate cancer.

Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20040101

Title: [Neoadjuvant hormone therapy with casodex in a dose 150 mg prior to radical prostatectomy in patients with prostatic cancer].

Journal: Urologiia (Moscow, Russia : 1999) 20040101

Title: Bicalutamide: clinical pharmacokinetics and metabolism.

Journal: Clinical pharmacokinetics 20040101

Title: Serum C-reactive protein (CRP) levels and insulin resistance in non-obese women with polycystic ovarian syndrome, and effect of bicalutamide on hirsutism, CRP levels and insulin resistance.

Journal: Hormone research 20040101

Title: Synergic effects of the cyclin-dependent kinase (CDK) inhibitor olomoucine and androgen-antagonist bicalutamide on prostatic cancer cell lines.

Journal: Neoplasma 20040101

Title: Which patients with prostate cancer are actually candidates for hormone therapy?

Journal: International braz j urol : official journal of the Brazilian Society of Urology 20040101

Title: Pilot attempt of advanced prostate cancer treatment T3NxMx-1 by intermittent more complete androgen blockade.

Journal: International urology and nephrology 20040101

Title: Success and failure of single-modality treatment for early prostate cancer.

Journal: Reviews in urology 20040101

Title: Bicalutamide adjuvant to radical prostatectomy.

Journal: Reviews in urology 20040101

Title: Immediate Treatment with Bicalutamide, 150 mg/d, Following Radiotherapy in Localized or Locally Advanced Prostate Cancer.

Journal: Reviews in urology 20040101

Title: Hormonal therapy options for patients with a rising prostate-specific antigen level after primary treatment for prostate cancer.

Journal: Urology 20031229

Title: Nucleophilic aromatic substitution of methacrylamide anion and its application to the synthesis of the anticancer drug bicalutamide.

Journal: The Journal of organic chemistry 20031226

Title: Antiandrogenic activities of diesel exhaust particle extracts in PC3/AR human prostate carcinoma cells.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20031201

Title: Bicalutamide monotherapy for early stage prostate cancer: an update.

Journal: The Journal of urology 20031201

Title: [Progress in researches on drugs for prostate cancer].

Journal: Zhonghua nan ke xue = National journal of andrology 20031201

Title: Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway.

Journal: Endocrinology 20031101

Title: Androgen dependent regulation of bacillus Calmette-Guerin induced interleukin-6 expression in human transitional carcinoma cell lines.

Journal: The Journal of urology 20031101

Title: Intermittent maximal androgen blockade in patients with metastatic prostate cancer: an EORTC feasibility study.

Journal: European urology 20031101

Title: Immediate treatment with bicalutamide 150mg as adjuvant therapy significantly reduces the risk of PSA progression in early prostate cancer.

Journal: European urology 20031101

Title: Alpha-methylacyl-CoA racemase as an androgen-independent growth modifier in prostate cancer.

Journal: Cancer research 20031101

Title: Hormonal and morphologic evaluation of the effects of antiandrogens on the blood supply of the rat prostate.

Journal: Urology 20031101

Title: Interstitial pneumonitis induced by bicalutamide and leuprorelin acetate for prostate cancer.

Journal: International journal of urology : official journal of the Japanese Urological Association 20031101

Title: [A case report of distant lymph nodes metastases from prostate cancer imaged with 201Tl and 99mTc-MIBI].

Journal: Kaku igaku. The Japanese journal of nuclear medicine 20031101

Title: Isolation and identification of L-dopa decarboxylase as a protein that binds to and enhances transcriptional activity of the androgen receptor using the repressed transactivator yeast two-hybrid system.

Journal: The Biochemical journal 20031015

Title: Adjuvant hormone therapy after radiation or surgery for localized or locally advanced prostate cancer.

Journal: Current treatment options in oncology 20031001

Title: The role of anti-androgen monotherapy in the treatment of prostate cancer.

Journal: BJU international 20031001

Title: [Comparative study of the effect of complete prolonged neoadjuvant hormonal blockade versus standard hormonal blockade].

Journal: Actas urologicas espanolas 20031001

Title: An oncology perspective on the benefits and cost of combined androgen blockade in advanced prostate cancer.

Journal: The Canadian journal of urology 20031001

Title: Estrogen regulates cytokine production and apoptosis in PMA-differentiated, macrophage-like U937 cells.

Journal: Journal of cellular biochemistry 20030901

Title: Osteoporosis and prostate cancer.

Journal: British journal of cancer 20030901

Title: Enhanced androgen receptor signaling correlates with the androgen-refractory growth in a newly established MDA PCa 2b-hr human prostate cancer cell subline.

Journal: Cancer research 20030901

Title: Is bicalutamide equivalent to goserelin for prostate volume reduction before radiation therapy? A prospective, observational study.

Journal: Clinical oncology (Royal College of Radiologists (Great Britain)) 20030901

Title: The clinical rationale for immediate androgen deprivation without estrogen deprivation.

Journal: Clinical prostate cancer 20030901

Title: Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis.

Journal: Oncogene 20030828

Title: Retinoic acid-induced stimulation of sodium iodide symporter expression and cytotoxicity of radioiodine in prostate cancer cells.

Journal: Endocrinology 20030801

Title: A complete remission with androgen-deprivation therapy in a recurrent androgen receptor-expressing adenocarcinoma of the parotid gland.

Journal: Annals of oncology : official journal of the European Society for Medical Oncology 20030801

Title: Gene expression changes following androgen receptor elimination in LNCaP prostate cancer cells.

Journal: Molecular carcinogenesis 20030801

Title: Impact of hormone therapy when combined with external beam radiotherapy for early-stage, intermediate-, or high-risk prostate cancer.

Journal: American journal of clinical oncology 20030801

Title: Pneumonitis and non steroidal antiandrogens.

Journal: Prescrire international 20030801

Title: Androgen antagonist activity by the antioxidant moiety of vitamin E, 2,2,5,7,8-pentamethyl-6-chromanol in human prostate carcinoma cells.

Journal: Molecular cancer therapeutics 20030801

Title: UV filters with antagonistic action at androgen receptors in the MDA-kb2 cell transcriptional-activation assay.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20030701

Title: Antiandrogen-induced cell death in LNCaP human prostate cancer cells.

Journal: Cell death and differentiation 20030701

Title: Androgens stimulate hypoxia-inducible factor 1 activation via autocrine loop of tyrosine kinase receptor/phosphatidylinositol 3'-kinase/protein kinase B in prostate cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030701

Title: Plant-derived 3,3'-Diindolylmethane is a strong androgen antagonist in human prostate cancer cells.

Journal: The Journal of biological chemistry 20030606

Title: Management of treatment-related osteoporosis in men with prostate cancer.

Journal: Cancer treatment reviews 20030601

Title: Neoadjuvant doxil chemotherapy prior to androgen ablation plus radiotherapy for high-risk localized prostate cancer: feasibility and toxicity.

Journal: American journal of clinical oncology 20030601

Title: [A case of primary transitional cell carcinoma of the prostate].

Journal: Hinyokika kiyo. Acta urologica Japonica 20030601

Title: [Effect of bicalutamide 150 mg, after 3 years of median follow-up, in non-metastatic prostatic cancer].

Journal: Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20030601

Title: Nilutamide as second line hormone therapy for prostate cancer after androgen ablation fails.

Journal: The Journal of urology 20030501

Title: Androgen stimulates matrix metalloproteinase-2 expression in human prostate cancer.

Journal: Endocrinology 20030501

Title: The non-steroidal antiandrogen, bicalutamide ('Casodex'), may preserve bone mineral density as compared with castration: results of a preliminary study.

Journal: World journal of urology 20030501

Title: [A case of locally advanced prostate cancer with low serum testosterone associated with intake of an androgenic medicine].

Journal: Nihon Hinyokika Gakkai zasshi. The japanese journal of urology 20030501

Title: Inhibition of fatty acid synthase expression by 1alpha,25-dihydroxyvitamin D3 in prostate cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20030501

Title: Bioassay of steroid hormone agonist and antagonist activities of anti-androgens on mammary gland, seminal vesicles and spleen of male mice.

Journal: Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20030501

Title: Store-operated Ca2+ current in prostate cancer epithelial cells. Role of endogenous Ca2+ transporter type 1.

Journal: The Journal of biological chemistry 20030425

Title: Attenuation of Ras signaling restores androgen sensitivity to hormone-refractory C4-2 prostate cancer cells.

Journal: Cancer research 20030415

Title: Constitutive activation of the Ras/mitogen-activated protein kinase signaling pathway promotes androgen hypersensitivity in LNCaP prostate cancer cells.

Journal: Cancer research 20030415

Title: Bicalutamide as immediate therapy either alone or as adjuvant to standard care of patients with localized or locally advanced prostate cancer: first analysis of the Early Prostate Cancer Program.

Journal: BJU international 20030401

Title: Newer approaches to androgen deprivation therapy in prostate cancer.

Journal: Urology 20030401

Title: [A case of prostate cancer with cyst formation].

Journal: Hinyokika kiyo. Acta urologica Japonica 20030401

Title: Impact of a novel neoadjuvant and adjuvant hormone-deprivation approach on quality of life, voiding function, and sexual function after prostate brachytherapy.

Journal: Cancer 20030301

Title: The role of antiandrogen monotherapy in the treatment of prostate cancer.

Journal: BJU international 20030301

Title: Diagnosis and management of treatment-related osteoporosis in men with prostate carcinoma.

Journal: Cancer 20030201

Title: A longer duration of neo-adjuvant combined androgen blockade prior to radical prostatectomy may lead to lower tumour volume of localised prostate cancer.

Journal: European urology 20030201

Title: Percentage of the positive area of bone metastasis is an independent predictor of disease death in advanced prostate cancer.

Journal: British journal of cancer 20030127

Title: Health related quality of life in prostate carcinoma patients: a systematic review of randomized controlled trials.

Journal: Cancer 20030115

Title: Key structural features of nonsteroidal ligands for binding and activation of the androgen receptor.

Journal: Molecular pharmacology 20030101

Title: Tissue polypeptide-specific antigen (TPS) determinations before and during intermittent maximal androgen blockade in patients with metastatic prostatic carcinoma.

Journal: European urology 20030101

Title: The transcriptional co-activator cAMP response element-binding protein-binding protein is expressed in prostate cancer and enhances androgen- and anti-androgen-induced androgen receptor function.

Journal: The American journal of pathology 20030101

Title: Role of the promyelocytic leukemia body in the dynamic interaction between the androgen receptor and steroid receptor coactivator-1 in living cells.

Journal: Molecular endocrinology (Baltimore, Md.) 20030101

Title: Novel mutations of androgen receptor: a possible mechanism of bicalutamide withdrawal syndrome.

Journal: Cancer research 20030101

Title: [First line therapy in the treatment of metastatic prostate cancer].

Journal: Gan to kagaku ryoho. Cancer & chemotherapy 20030101

Title: Cross-sectional study of bone turnover during bicalutamide monotherapy for prostate cancer.

Journal: Urology 20030101

Title: Immediate or deferred hormonal therapy?

Journal: Scandinavian journal of urology and nephrology. Supplementum 20030101

Title: Adjuvant hormonal treatment for prostate cancer: the bicalutamide early prostate cancer program.

Journal: Oncology 20030101

Title: Biochemical recurrence of prostate cancer.

Journal: Current problems in cancer 20030101

Title: Elevated E-cadherin and alpha/beta-catenin expression after androgen deprivation therapy in prostate adenocarcinoma.

Journal: Pathology, research and practice 20030101

Title: Therapeutic androgen receptor ligands.

Journal: Nuclear receptor signaling 20030101

Title: Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex.

Journal: The Journal of biological chemistry 20021213

Title: Androgen receptors in human melanoma cell lines IIB-MEL-LES and IIB-MEL-IAN and in human melanoma metastases.

Journal: Melanoma research 20021201

Title: Luteinising hormone releasing hormone analogues in the treatment of prostate cancer.

Journal: Expert opinion on pharmacotherapy 20021201

Title: Studies with CWR22 xenografts in nude mice suggest that ZD1839 may have a role in the treatment of both androgen-dependent and androgen-independent human prostate cancer.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20021201

Title: [Antiandrogen in prostate cancer].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20021201

Title: [Total androgen blockade].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20021201

Title: Induction of invasive phenotype by Casodex in hormone-sensitive prostate cancer cells.

Journal: The Journal of steroid biochemistry and molecular biology 20021201

Title: Bicalutamide monotherapy versus flutamide plus goserelin in prostate cancer: updated results of a multicentric trial.

Journal: European urology 20021101

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20021101

Title: Unusual anti-angiogenic effect of combined hormonal blockade.

Journal: The Journal of urology 20021001

Title: Pneumonitis associated with nonsteroidal antiandrogens: presumptive evidence of a class effect.

Journal: Annals of internal medicine 20021001

Title: Identification of human male germ cell-associated kinase, a kinase transcriptionally activated by androgen in prostate cancer cells.

Journal: The Journal of biological chemistry 20020920

Title: An evaluation of bicalutamide in the treatment of prostate cancer.

Journal: Expert opinion on pharmacotherapy 20020901

Title: Emerging role of adjuvant hormonal therapy.

Journal: Urology 20020901

Title: Antiandrogen monotherapy: indications and results.

Journal: Urology 20020901

Title: Osteoporosis during androgen deprivation therapy for prostate cancer.

Journal: Urology 20020901

Title: Secondary hormonal therapies in the treatment of prostate cancer.

Journal: Urology 20020901

Title: Androgen receptor as a target in androgen-independent prostate cancer.

Journal: Urology 20020901

Title: A randomised comparison of bicalutamide ('Casodex') 150 mg versus placebo as immediate therapy either alone or as adjuvant to standard care for early non-metastatic prostate cancer. First report from the Scandinavian Prostatic Cancer Group Study No. 6.

Journal: European urology 20020901

Title: Tolerability assessment of maximal androgen blockade with 50 mg daily of bicalutamide and castration in patients with advanced prostate cancer.

Journal: Chang Gung medical journal 20020901

Title: Highlights from the 97th Annual Meeting of the American Urological Association: Orlando, Florida, May 25-30, 2002.

Journal: Clinical prostate cancer 20020901

Title: Bicalutamide as immediate therapy either alone or as adjuvant to standard care of patients with localized or locally advanced prostate cancer: first analysis of the early prostate cancer program.

Journal: The Journal of urology 20020801

Title: Regulation of FGF8 expression by the androgen receptor in human prostate cancer.

Journal: Oncogene 20020801

Title: Novel nonsteroidal ligands with high binding affinity and potent functional activity for the androgen receptor.

Journal: European journal of medicinal chemistry 20020801

Title: Bicalutamide functions as an androgen receptor antagonist by assembly of a transcriptionally inactive receptor.

Journal: The Journal of biological chemistry 20020719

Title: Pure antiandrogens disrupt the recruitment of coactivator GRIP1 to colocalize with androgen receptor in nuclei.

Journal: FEBS letters 20020717

Title: Effects of complete androgen blockade for 12 and 24 weeks on the pathological stage and resection margin status of prostate cancer.

Journal: Journal of clinical pathology 20020701

Title: Acquisition of agonistic properties of nonsteroidal antiandrogens after treatment with oncostatin M in prostate cancer cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20020701

Title: Stabilization of androgen receptor protein is induced by agonist, not by antagonists.

Journal: Biochemical and biophysical research communications 20020621

Title: Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells.

Journal: The Journal of biological chemistry 20020607

Title: A glucocorticoid-responsive mutant androgen receptor exhibits unique ligand specificity: therapeutic implications for androgen-independent prostate cancer.

Journal: Endocrinology 20020501

Title: AR possesses an intrinsic hormone-independent transcriptional activity.

Journal: Molecular endocrinology (Baltimore, Md.) 20020501

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020501

Title: A phase 3, multicenter, open label, randomized study of abarelix versus leuprolide plus daily antiandrogen in men with prostate cancer.

Journal: The Journal of urology 20020401

Title: The amino terminus of the human AR is target for corepressor action and antihormone agonism.

Journal: Molecular endocrinology (Baltimore, Md.) 20020401

Title: [The role of bicalutamide in the treatment of prostate cancer].

Journal: Harefuah 20020401

Title: The effects of natural ligands of hormone receptors and their antagonists on telomerase activity in the androgen sensitive prostatic cancer cell line LNCaP.

Journal: Biochemical pharmacology 20020315

Title: Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways.

Journal: The Journal of biological chemistry 20020301

Title: [Adjuvant treatment of prostatic carcinoma after primary therapy. The 'Early Prostate Cancer' Program].

Journal: Recenti progressi in medicina 20020301

Title: [Adjuvant hormone therapy in prostatic cancer: after treatment with curative intent. The viewpoint of the urologist].

Journal: Recenti progressi in medicina 20020301

Title: [Efficacy of bicalutamide in adjuvant treatment of prostatic carcinoma after primary therapy with curative aim. The viewpoint of the surgeon].

Journal: Recenti progressi in medicina 20020301

Title: Bone alkaline phosphatase serum level predicts the response to antiandrogen withdrawal.

Journal: European urology 20020301

Title: AIbZIP, a novel bZIP gene located on chromosome 1q21.3 that is highly expressed in prostate tumors and of which the expression is up-regulated by androgens in LNCaP human prostate cancer cells.

Journal: Cancer research 20020201

Title: Normalization of serum testosterone levels in patients treated with neoadjuvant hormonal therapy and three-dimensional conformal radiotherapy for prostate cancer.

Journal: International journal of radiation oncology, biology, physics 20020201

Title: Effect of bicalutamide therapy on prolactin response to L-dopa in metastatic prostate cancer patients.

Journal: Neuro endocrinology letters 20020201

Title: New alternative treatment in hirsutism: bicalutamide 25 mg/day.

Journal: Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20020201

Title: Low serum testosterone level predicts worse response to endocrine therapy in Japanese patients with metastatic prostate cancer.

Journal: Endocrine journal 20020201

Title: Antiandrogens in the treatment of priapism.

Journal: Urology 20020101

Title: Comparative study of pressure-flow parameters.

Journal: Neurourology and urodynamics 20020101

Title: Prostate-specific antigen dynamics predict risk of progression in advanced prostate cancer treated with bicalutamide plus castration.

Journal: Urologia internationalis 20020101

Title: Gateways to clinical trials.

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: [Monotherapy with casodex at a dose of 150 mg--a new method of hormonal treatment of disseminated prostatic cancer].

Journal: Urologiia (Moscow, Russia : 1999) 20020101

Title: Bicalutamide: in early-stage prostate cancer.

Journal: Drugs 20020101

Title: The roles of sex steroid receptor coregulators in cancer.

Journal: Molecular cancer 20020101

Title: Bicalutamide dose-dependently inhibits proliferation in human prostatic carcinoma cell lines and primary cultures.

Journal: Anticancer research 20020101

Title: Androgen deprivation in men with prostate cancer is associated with an increased rate of bone loss.

Journal: Prostate cancer and prostatic diseases 20020101

Title: Androgen receptor alterations in prostate cancer relapsed during a combined androgen blockade by orchiectomy and bicalutamide.

Journal: Laboratory investigation; a journal of technical methods and pathology 20011201

Title: Nilutamide: possible utility as a second-line hormonal agent.

Journal: Urology 20011201

Title: Human prostatic cell line PNT1A, a useful tool for studying androgen receptor transcriptional activity and its differential subnuclear localization in the presence of androgens and antiandrogens.

Journal: Molecular and cellular endocrinology 20011126

Title: Metastatic prostate cancer to the spine and a PSA of 5666: a case report.

Journal: Pain physician 20011001

Title: Effect of an EGF-R selective tyrosine kinase inhibitor and an anti-androgen on LNCaP cells: identification of divergent growth regulatory pathways.

Journal: The Prostate 20010915

Title: The antiosteoporotic efficacy of intravenous pamidronate in men with prostate carcinoma receiving combined androgen blockade: a double blind, randomized, placebo-controlled crossover study.

Journal: Cancer 20010915

Title: Androgen responsiveness of the pituitary gonadotrope cell line LbetaT2.

Journal: The Journal of endocrinology 20010901

Title: Prostate cancer in the older man.

Journal: Oncology (Williston Park, N.Y.) 20010901

Title: Bicalutamide (Casodex) 150 mg as immediate therapy in patients with localized or locally advanced prostate cancer significantly reduces the risk of disease progression.

Journal: Urology 20010801

Title: Antiandrogen monotherapy: a new form of treatment for patients with prostate cancer.

Journal: Urology 20010801

Title: Luteinizing hormone-releasing hormone antagonists in prostate cancer.

Journal: Urology 20010801

Title: [Intermittent androgen deprivation treatment of prostate cancer restarted at low level of serum prostate specific antigen: a pilot study].

Journal: Hinyokika kiyo. Acta urologica Japonica 20010801

Title: Docetaxel followed by hormone therapy after failure of definitive treatments for clinically localized/locally advanced prostate cancer: preliminary results.

Journal: Seminars in oncology 20010801

Title: Docetaxel, estramustine, and short-term androgen withdrawal for patients with biochemical failure after definitive local therapy for prostate cancer.

Journal: Seminars in oncology 20010801

Title: The subnuclear three-dimensional image analysis of androgen receptor fused to green fluorescence protein.

Journal: The Journal of biological chemistry 20010727

Title: Phase II trial of bicalutamide in patients with advanced prostate cancer in whom conventional hormonal therapy failed: a Southwest Oncology Group study (SWOG 9235).

Journal: Urology 20010701

Title: Why phase III trials of maximal androgen blockade versus castration in M1 prostate cancer rarely show statistically significant differences.

Journal: The Prostate 20010615

Title: Interleukin-6 induces androgen responsiveness in prostate cancer cells through up-regulation of androgen receptor expression.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010601

Title: New drug for prostate cancer.

Journal: European journal of cancer care 20010601

Title: Prostate-specific antigen-all that rises is not refractory.

Journal: Urology 20010501

Title: CaT1 expression correlates with tumor grade in prostate cancer.

Journal: Biochemical and biophysical research communications 20010406

Title: Androgen antagonists: Potential role in prostate cancer prevention.

Journal: Urology 20010401

Title: The effect of bicalutamide on prostate histology.

Journal: The Prostate 20010301

Title: Long-term exposure of tumor necrosis factor alpha causes hypersensitivity to androgen and anti-androgen withdrawal phenomenon in LNCaP prostate cancer cells.

Journal: The Prostate 20010301

Title: Effects of long-term treatment with the anti-androgen bicalutamide on human testis: an ultrastructural and morphometric study.

Journal: Histopathology 20010301

Title: Cross-talk between steroid-receptor-mediated and cell-membrane-receptor-mediated signalling pathways results in the in vivo modulation of c-Met and ornithine decarboxylase gene expression in mouse kidney.

Journal: The Biochemical journal 20010115

Title: Treatment of locally advanced prostate cancer--a new role for antiandrogen monotherapy?

Journal: European urology 20010101

Title: Nonsteroidal antiandrogens: a therapeutic option for patients with advanced prostate cancer who wish to retain sexual interest and function.

Journal: BJU international 20010101

Title: A reexamination of PSC 833 (Valspodar) as a cytotoxic agent and in combination with anticancer agents.

Journal: Cancer chemotherapy and pharmacology 20010101

Title: Levels of alpha 2 macroglobulin can predict bone metastases in prostate cancer.

Journal: Anticancer research 20010101

Title: Treatment of localized prostate cancer with intermittent triple androgen blockade: preliminary results in 110 consecutive patients.

Journal: The oncologist 20010101

Title: Ultrastructural and quantitative immunohistochemical changes induced by nonsteroid antiandrogens on pituitary gonadotroph population of prepubertal male rats.

Journal: Cells, tissues, organs 20010101

Title: [Bicalutamide monotherapy of patients with disseminated forms of prostatic cancer].

Journal: Urologiia (Moscow, Russia : 1999) 20010101

Title: [Changes in prostate-specific antigen in casodex (bicalutamide) monotherapy in a dose 150 mg/day given to patients with locally advanced and/or advanced prostatic cancer].

Journal: Urologiia (Moscow, Russia : 1999) 20010101

Title: Delaying/reducing the risk of clinical tumour progression after primary curative procedures.

Journal: European urology 20010101

Title: Quality of life aspects of treatment options for localized and locally advanced prostate cancer.

Journal: European urology 20010101

Title: Neither fibroblast growth factor-1 nor fibroblast growth factor-2 is an androgen receptor coactivator in androgen-resistant prostate cancer.

Journal: Molecular urology 20010101

Title: [Preliminary results of casodex use in patients with hormone-resistant cancer of the prostate].

Journal: Urologiia (Moscow, Russia : 1999) 20010101

Title: Androgen sensitivity related proteins in hormone-sensitive and hormone-insensitive prostate cancer cell lines treated by androgen antagonist bicalutamide.

Journal: Neoplasma 20010101

Title: Androgen receptor mutations in carcinoma of the prostate: significance for endocrine therapy.

Journal: American journal of pharmacogenomics : genomics-related research in drug development and clinical practice 20010101

Title: Androgen deprivation and other treatments for advanced prostate cancer.

Journal: Reviews in urology 20010101

Title: Flare Associated with LHRH-Agonist Therapy.

Journal: Reviews in urology 20010101

Title: Emerging pharmacologic therapies for prostate cancer.

Journal: Reviews in urology 20010101

Title: TACC2 is an androgen-responsive cell cycle regulator promoting androgen-mediated and castration-resistant growth of prostate cancer.

Journal: Molecular endocrinology (Baltimore, Md.)

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