Name: Name:MK-0941
Brand: AABLOCKS
SKU: AA0096JQ
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0096JQ

Chemical Name: MK-0941

CAS Number: 1137916-97-2

Molecular Formula: C22H28N4O9S2

Molecular Weight: 556.6091

MDL Number: MFCD30532700

SMILES: CS(=O)(=O)O.OC[C@@H](Oc1cc(Oc2ccc(nc2)S(=O)(=O)CC)cc(c1)C(=O)Nc1ccn(n1)C)C

Properties

Complexity: 810

Covalently-Bonded Unit Count: 2

Defined Atom Stereocenter Count: 1

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 37

Hydrogen Bond Acceptor Count: 11

Hydrogen Bond Donor Count: 3

Isotope Atom Count: 0

Rotatable Bond Count: 9

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

Literature fold

Title: Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs.

Journal: Molecular pharmacology20111201

Title: Effects of MK-0941, a novel glucokinase activator, on glycemic control in insulin-treated patients with type 2 diabetes.

Journal: Diabetes care20111201

Title: Eiki J, et al. Pharmacokinetic and pharmacodynamic properties of the glucokinase activator MK-0941 in rodent models of type 2 diabetes and healthy dogs. Mol Pharmacol. 2011 Dec;80(6):1156-65.

1137916-97-2 | MK-0941