Catalog No.:AA01EO0J

1142363-52-7 | JNJ-40346527

Name: Name:JNJ-40346527
Brand: AABLOCKS
SKU: AA01EO0J
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

Availability

Price(USD)

Quantity

1mg

97%

in stock

$29.00 $21.00

- +

5mg

97%

in stock

$74.00 $52.00

- +

Technical Information
Properties
Downstream Synthesis Route
Literature
Request for Quotation
Download SDS

Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA01EO0J

Chemical Name:

JNJ-40346527

CAS Number:

1142363-52-7

Molecular Formula:

C27H35N5O2

Molecular Weight:

461.5991

MDL Number:

MFCD30489233

SMILES:

N#Cc1cnc([nH]1)C(=O)Nc1ccc(nc1C1=CCC(CC1)(C)C)C1CC(C)(C)OC(C1)(C)C

Properties

Computed Properties

Complexity:

838

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

XLogP3:

4.3

Downstream Synthesis Route

75-75-2

1142363-52-7

4-cyano-1H-imidazole-2-carboxylicacid2-(4,4-dimethyl-cyclohex-1-enyl)-6-(2,2,6,6-tetramethyl-tetrahydro-pyran-4-yl)-pyridin-3-yl-amidemethanesulfonate

[1]Patent:US2009/105296,2009,A1.Locationinpatent:Page/Pagecolumn54

1142363-52-7

3144-16-9

4-cyano-1H-imidazole-2-carboxylicacid2-(4,4-dimethyl-cyclohex-1-enyl)-6-(2,2,6,6-tetramethyl-tetrahydro-pyran-4-yl)-pyridin-3-yl-amide(1S)-(+)-10-camphorsulfonate

[1]Patent:US2009/105296,2009,A1.Locationinpatent:Page/Pagecolumn54

1142363-52-7

4-cyano-1H-imidazole-2-carboxylicacid2-(4,4-dimethyl-cyclohex-1-enyl)-6-(2,2,6,6-tetramethyl-tetrahydro-pyran-4-yl)-pyridin-3-yl-amidehydrochloride

[1]Patent:US2009/105296,2009,A1.Locationinpatent:Page/Pagecolumn53

1142363-52-7

4-cyano-1H-imidazole-2-carboxylicacid2-(4,4-dimethyl-cyclohex-1-enyl)-6-(2,2,6,6-tetramethyl-tetrahydro-pyran-4-yl)-pyridin-3-yl-amidesulfate

[1]Patent:US2009/105296,2009,A1.Locationinpatent:Page/Pagecolumn56

1142363-66-3

1142363-52-7

[1]Patent:US2009/105296,2009,A1.Locationinpatent:Page/Pagecolumn45

Literature

Title: Results from a Phase IIA Parallel Group Study of JNJ-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-modifying Antirheumatic Drug Therapy.

Journal: The Journal of rheumatology 20151001

Quotation Request

Company Name:

Contact Person:

Email:

Quantity Required:

Country:

Additional Info:

SDS