Title: Modulation of Cytotoxicity by Transcription-Coupled Nucleotide Excision Repair Is Independent of the Requirement for Bioactivation of Acylfulvene.
Journal: Chemical research in toxicology 20170320
Title: Sulfotransferase-independent genotoxicity of illudin S and its acylfulvene derivatives in bacterial and mammalian cells.
Journal: Archives of toxicology 20140101
Title: Draft genome of Omphalotus olearius provides a predictive framework for sesquiterpenoid natural product biosynthesis in Basidiomycota.
Journal: Chemistry & biology 20120622
Title: Chemical and enzymatic reductive activation of acylfulvene to isomeric cytotoxic reactive intermediates.
Journal: Chemical research in toxicology 20111121
Title: Susceptibility of the antioxidant selenoenyzmes thioredoxin reductase and glutathione peroxidase to alkylation-mediated inhibition by anticancer acylfulvenes.
Journal: Chemical research in toxicology 20110516
Title: Profiling patterns of glutathione reductase inhibition by the natural product illudin S and its acylfulvene analogues.
Journal: Molecular bioSystems 20090901
Title: NADPH alkenal/one oxidoreductase activity determines sensitivity of cancer cells to the chemotherapeutic alkylating agent irofulven.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040215
Title: Marked activity of irofulven toward human carcinoma cells: comparison with cisplatin and ecteinascidin.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20030701
Title: Reaction of irofulven with zinc and acid.
Journal: Journal of natural products 20030201
Title: Anti-tumour compounds illudin S and Irofulven induce DNA lesions ignored by global repair and exclusively processed by transcription- and replication-coupled repair pathways.
Journal: DNA repair 20021205