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115-33-3,MFCD00022793
Catalog No.:AA008X9W

115-33-3 | oxyphenisatine di(acetate)

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5mg
95%
1 week  
$92.00   $64.00
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10mg
95%
1 week  
$111.00   $78.00
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25mg
95%
1 week  
$131.00   $92.00
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50mg
95%
1 week  
$146.00   $102.00
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100mg
95%
1 week  
$180.00   $126.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008X9W
Chemical Name:
oxyphenisatine di(acetate)
CAS Number:
115-33-3
Molecular Formula:
C24H19NO5
Molecular Weight:
401.4114
MDL Number:
MFCD00022793
SMILES:
CC(=O)Oc1ccc(cc1)C1(c2ccc(cc2)OC(=O)C)C(=O)Nc2c1cccc2
Properties
Computed Properties
 
Complexity:
625  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
3.5  

Downstream Synthesis Route

[1]Inagaki[YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1933,vol.53,p.686,696;dtsch.Ref.S.133][ChemischesZentralblatt,1933,vol.104,#II,p.2133]

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-DE447539,1927,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693]

[2]CurrentPatentAssignee:ROCHEHOLDINGAG-DE447539,1927,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693]

[3]CurrentPatentAssignee:ROCHEHOLDINGAG-DE447539,1927,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693]

[4]CurrentPatentAssignee:ROCHEHOLDINGAG-DE482435,1929,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521]CurrentPatentAssignee:ROCHEHOLDINGAG-DE406210,1924,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412]

[5]CurrentPatentAssignee:ROCHEHOLDINGAG-DE482435,1929,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521]CurrentPatentAssignee:ROCHEHOLDINGAG-DE406210,1924,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412]

[6]CurrentPatentAssignee:ROCHEHOLDINGAG-DE482435,1929,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521]CurrentPatentAssignee:ROCHEHOLDINGAG-DE406210,1924,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412]

125-13-3   
CASUnavailable 
  115-33-3 

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-DE447539,1927,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693]

[2]CurrentPatentAssignee:ROCHEHOLDINGAG-DE482435,1929,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521]CurrentPatentAssignee:ROCHEHOLDINGAG-DE406210,1924,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412]

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-DE447539,1927,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.15,p.1693]

[2]CurrentPatentAssignee:ROCHEHOLDINGAG-DE482435,1929,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.16,p.2519,2521]CurrentPatentAssignee:ROCHEHOLDINGAG-DE406210,1924,C[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.14,p.1412]

[1]CurrentPatentAssignee:Orelup-US2041856,1932,A

[2]CurrentPatentAssignee:Hoffmann-LaRoche-DE555813,1931[Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.19,p.1431][Fortschr.Teerfarbenfabr.Verw.Industriezweige,vol.19,p.1431]

[3]Nakazawa;Matsuura[YakugakuZasshi/JournalofthePharmaceuticalSocietyofJapan,1954,vol.74,p.69][Chem.Abstr.,1955,p.1631]

Literature

Title: Influence of modification in core building procedure on fracture strength and failure patterns of premolars restored with fiber post and composite core.

Journal: The journal of advanced prosthodontics 20120201

Title: A proposal of microtomography evaluation for restoration interface gaps.

Journal: Annali dell'Istituto superiore di sanita 20120101

Title: Novel small molecule drugs inhibit tumor cell metabolism and show potent anti-tumorigenic potential.

Journal: Cancer chemotherapy and pharmacology 20110701

Title: Comparing the reinforcing effects of a resin modified glassionomer cement, Flowable compomer, and Flowable composite in the restoration of calcium hydroxide-treated immature roots in vitro.

Journal: Contemporary clinical dentistry 20110101

Title: Comparative evaluation of microleakage of two self-etching dentin bonding agents on primary and permanent teeth. An in vitro study.

Journal: European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry 20100901

Title: The effect of bevacizumab on corneal neovascularization in rabbits.

Journal: Korean journal of ophthalmology : KJO 20100801

Title: Adhesion of resin core foundation composites to root canal dentin using different dentin adhesives.

Journal: American journal of dentistry 20100401

Title: Comparative evaluation of shear bond strength of two self-etching adhesives (sixth and seventh generation) on dentin of primary and permanent teeth: an in vitro study.

Journal: Journal of the Indian Society of Pedodontics and Preventive Dentistry 20090101

Title: Retention of gold alloy crowns cemented with traditional and resin cements.

Journal: The International journal of prosthodontics 20090101

Title: [Two-dimensional morphology of microleakage between dentin and adhesives].

Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20080201

Title: Syntheses and antiproliferative evaluation of oxyphenisatin derivatives.

Journal: Bioorganic & medicinal chemistry letters 20070515

Title: [Study of different adhesive systems adhesion to dentine].

Journal: Stomatologiia 20070101

Title: [Micro-tensile bond strength to sclerotic dentin in non-carious cervical lesions].

Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20060901

Title: Morphological evaluation of 2- and 1-step self-etching system interfaces with dentin.

Journal: Operative dentistry 20060101

Title: [Ultrastructural study of a self-etching adhesive to sclerotic dentin in non-carious cervical lesions].

Journal: Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20050501

Title: Efficient expression of transgenes in adult zebrafish by electroporation.

Journal: BMC biotechnology 20050101

Title: Long-lasting restorations using compatible dual-cured materials.

Journal: Dentistry today 20040201

Title: Treatment of cancer with cryochemotherapy.

Journal: British journal of cancer 20020520

Title: Drug-induced hepatitis associated with anticytoplasmic organelle autoantibodies.

Journal: Hepatology (Baltimore, Md.) 19850101

Title: Hepatic drug metabolism and adverse hepatic drug reactions.

Journal: Veterinary pathology 19750101

Title: Morrison BL, et al. Oxyphenisatin acetate (NSC 59687) triggers a cell starvation response leading to autophagy, mitochondrial dysfunction, and autocrine TNFα-mediated apoptosis. Cancer Med. 2013 Oct;2(5):687-700.

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