115-69-5,MFCD00004678
Catalog No.:AA000FHV

115-69-5 | 2-Amino-2-methyl-1,3-propanediol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
95%
in stock  
$24.00   $17.00
- +
5g
98%
in stock  
$27.00   $19.00
- +
25g
98%
in stock  
$51.00   $36.00
- +
100g
>98.0%(GC)(T)
in stock  
$110.00   $77.00
- +
500g
>98.0%(GC)(T)
in stock  
$438.00   $307.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA000FHV
Chemical Name:
2-Amino-2-methyl-1,3-propanediol
CAS Number:
115-69-5
Molecular Formula:
C4H11NO2
Molecular Weight:
105.1356
MDL Number:
MFCD00004678
SMILES:
OCC(CO)(N)C
NSC Number:
6364
Properties
Properties
 
BP:
271.5±0.0 °C at 760 mmHg  
Form:
Solid  
MP:
100-110°C  
Storage:
Room Temperature;Light sensitive;Inert atmosphere;  

Computed Properties
 
Complexity:
51.7  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-1.8  

Downstream Synthesis Route

[1]CurrentPatentAssignee:COMMERCIALSOLVENTSCORPORATION-US2413153,1943,A

[2]Johnson;Degering[JournalofOrganicChemistry,1943,vol.8,p.11]

[3]Senkus[IndustrialandEngineeringChemistry,1948,vol.40,p.507]

[4]Piloty;Ruff[ChemischeBerichte,1897,vol.30,p.2058]

[5]Demjanov[ZhurnalRusskagoFiziko-KhimicheskagoObshchestva,1903,vol.35,p.25][ChemischesZentralblatt,1903,vol.74,#I,p.816]

[1]JournaloftheAmericanChemicalSociety,1945,vol.67,p.1517

[2]BulletindelaSocieteChimiquedeFrance,1967,p.3868-3872

[3]Patent:US2448890,1941,A

[1]Eknoian,MichaelW.;Webb,ThomasR.;Worley,S.Davis;Fleury,JenniferR.;Maddox,SpencerD.[ActaCrystallographica,SectionC:CrystalStructureCommunications,1998,vol.54,#10,p.1529-1532]

[2]CurrentPatentAssignee:NOVABAYPHARMACEUTICALS,INC.-WO2010/54009,2010,A1Locationinpatent:Page/Pagecolumn51-52

[3]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2015/35278,2015,A1Locationinpatent:Page/Pagecolumn56

[4]CurrentPatentAssignee:MALLINCKRODTPUBLICLIMITEDCOMPANY-US2399118,1942,A

[1]JournaloftheAmericanChemicalSociety,1944,vol.67,p.1516

[1]JournalofHeterocyclicChemistry,1976,vol.13,p.337-348

Literature

Title: Spectrophotometric calibration of pH electrodes in seawater using purified m-cresol purple.

Journal: Environmental science & technology 20120501

Title: 2-[(5-Chloro-2-oxidobenzyl-idene)aza-nium-yl]-2-methyl-propane-1,3-diol.

Journal: Acta crystallographica. Section E, Structure reports online 20120201

Title: Impact of the counterion on the solubility and physicochemical properties of salts of carboxylic acid drugs.

Journal: Drug development and industrial pharmacy 20120101

Title: Environmental factors affecting the expression of pilAB as well as the proteome and transcriptome of the grass endophyte Azoarcus sp. strain BH72.

Journal: PloS one 20120101

Title: Pi sampling: a methodical and flexible approach to initial macromolecular crystallization screening.

Journal: Acta crystallographica. Section D, Biological crystallography 20110501

Title: Prolonged survival and phenotypic correction of Akp2(-/-) hypophosphatasia mice by lentiviral gene therapy.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110101

Title: Comparative physical, mechanical and crystallographic properties of a series of gemfibrozil salts.

Journal: The Journal of pharmacy and pharmacology 20101101

Title: SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts.

Journal: BMC molecular biology 20100101

Title: Final amended report on safety assessment on aminomethyl propanol and aminomethyl propanediol.

Journal: International journal of toxicology 20090101

Title: Potential impact of stress activated retrotransposons on genome evolution in a marine diatom.

Journal: BMC genomics 20090101

Title: Mixed-valent Mn supertetrahedra and planar discs as enhanced magnetic coolers.

Journal: Journal of the American Chemical Society 20080820

Title: Influence of additives including amine and hydroxyl groups on aqueous ammonia absorbent for CO2 capture.

Journal: The journal of physical chemistry. B 20080410

Title: A new family of octanuclear Cu4Ln4 (Ln = Gd, Tb and Dy) spin clusters.

Journal: Dalton transactions (Cambridge, England : 2003) 20080107

Title: Dirhodium(II)-catalyzed C-H amination reaction of (S)-3-(tert-butyldimethylsilyloxy)-2-methylpropyl carbamate: a facile preparation of optically active monoprotected 2-amino-2-methyl-1,3-propanediol.

Journal: Chemical & pharmaceutical bulletin 20070901

Title: Mixed-valent cobalt spin clusters: a hexanuclear complex and a one-dimensional coordination polymer comprised of alternating hepta- and mononuclear fragments.

Journal: Inorganic chemistry 20061030

Title: ATR-FTIR characterization of transport properties of benzoic acid ion-pairs in silicone membranes.

Journal: International journal of pharmaceutics 20040928

Title: In vitro effect of a buffered chelating agent and neomycin or oxytetracycline on bacteria associated with diseases of fish.

Journal: Diseases of aquatic organisms 20040611

Title: Electrospray mass spectrometry studies of macromolecules containing 1,3-oxazolidine moieties.

Journal: Rapid communications in mass spectrometry : RCM 20040101

Title: Ultrathin-layer sodium dodecyl sulfate disc electrophoresis of proteins in the range from 10 to 220 kDa in homogeneous, low-concentrated polyacrylamide gels.

Journal: Electrophoresis 20030701

Title: Effect of steric hindrance on carbon dioxide absorption into new amine solutions: thermodynamic and spectroscopic verification through solubility and NMR analysis.

Journal: Environmental science & technology 20030415

Title: Function of mutant (G1144A) tissue-nonspecific ALP gene from hypophosphatasia.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021101

Title: Effect of a basic organic excipient on the dissolution of diclofenac salts.

Journal: Journal of pharmaceutical sciences 20021001

Title: Preparation and characterisation of a range of diclofenac salts.

Journal: International journal of pharmaceutics 20010911

Quotation Request
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Additional Info:
SDS
Historical Records
Tags:115-69-5 Molecular Formula|115-69-5 MDL|115-69-5 SMILES|115-69-5 2-Amino-2-methyl-1,3-propanediol
Catalog No.: AA000FHV
115-69-5,MFCD00004678
115-69-5 | 2-Amino-2-methyl-1,3-propanediol
Pack Size: 1g
Purity: 95%
in stock
$24.00 $17.00
Pack Size: 5g
Purity: 98%
in stock
$27.00 $19.00
Pack Size: 25g
Purity: 98%
in stock
$51.00 $36.00
Pack Size: 100g
Purity: >98.0%(GC)(T)
in stock
$110.00 $77.00
Pack Size: 500g
Purity: >98.0%(GC)(T)
in stock
$438.00 $307.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA000FHV
Chemical Name: 2-Amino-2-methyl-1,3-propanediol
CAS Number: 115-69-5
Molecular Formula: C4H11NO2
Molecular Weight: 105.1356
MDL Number: MFCD00004678
SMILES: OCC(CO)(N)C
NSC Number: 6364
Properties
BP: 271.5±0.0 °C at 760 mmHg  
Form: Solid  
MP: 100-110°C  
Storage: Room Temperature;Light sensitive;Inert atmosphere;  
Complexity: 51.7  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 7  
Hydrogen Bond Acceptor Count: 3  
Hydrogen Bond Donor Count: 3  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -1.8  
Downstream Synthesis Route
77-49-6    115-69-5 

[1]CurrentPatentAssignee:COMMERCIALSOLVENTSCORPORATION-US2413153,1943,A

[2]Johnson;Degering[JournalofOrganicChemistry,1943,vol.8,p.11]

[3]Senkus[IndustrialandEngineeringChemistry,1948,vol.40,p.507]

[4]Piloty;Ruff[ChemischeBerichte,1897,vol.30,p.2058]

[5]Demjanov[ZhurnalRusskagoFiziko-KhimicheskagoObshchestva,1903,vol.35,p.25][ChemischesZentralblatt,1903,vol.74,#I,p.816]

50-00-0    115-69-5    7747-34-4 

[1]JournaloftheAmericanChemicalSociety,1945,vol.67,p.1517

[2]BulletindelaSocieteChimiquedeFrance,1967,p.3868-3872

[3]Patent:US2448890,1941,A

115-69-5    105-58-8    6629-85-2 

[1]Eknoian,MichaelW.;Webb,ThomasR.;Worley,S.Davis;Fleury,JenniferR.;Maddox,SpencerD.[ActaCrystallographica,SectionC:CrystalStructureCommunications,1998,vol.54,#10,p.1529-1532]

[2]CurrentPatentAssignee:NOVABAYPHARMACEUTICALS,INC.-WO2010/54009,2010,A1Locationinpatent:Page/Pagecolumn51-52

[3]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2015/35278,2015,A1Locationinpatent:Page/Pagecolumn56

[4]CurrentPatentAssignee:MALLINCKRODTPUBLICLIMITEDCOMPANY-US2399118,1942,A

50-00-0    115-69-5    71-43-2    7747-34-4 

[1]JournaloftheAmericanChemicalSociety,1944,vol.67,p.1516

2955-65-9    115-69-5    60204-80-0 

[1]JournalofHeterocyclicChemistry,1976,vol.13,p.337-348

Literature fold

Title: Spectrophotometric calibration of pH electrodes in seawater using purified m-cresol purple.

Journal: Environmental science & technology20120501

Title: 2-[(5-Chloro-2-oxidobenzyl-idene)aza-nium-yl]-2-methyl-propane-1,3-diol.

Journal: Acta crystallographica. Section E, Structure reports online20120201

Title: Impact of the counterion on the solubility and physicochemical properties of salts of carboxylic acid drugs.

Journal: Drug development and industrial pharmacy20120101

Title: Environmental factors affecting the expression of pilAB as well as the proteome and transcriptome of the grass endophyte Azoarcus sp. strain BH72.

Journal: PloS one20120101

Title: Pi sampling: a methodical and flexible approach to initial macromolecular crystallization screening.

Journal: Acta crystallographica. Section D, Biological crystallography20110501

Title: Prolonged survival and phenotypic correction of Akp2(-/-) hypophosphatasia mice by lentiviral gene therapy.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research20110101

Title: Comparative physical, mechanical and crystallographic properties of a series of gemfibrozil salts.

Journal: The Journal of pharmacy and pharmacology20101101

Title: SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts.

Journal: BMC molecular biology20100101

Title: Final amended report on safety assessment on aminomethyl propanol and aminomethyl propanediol.

Journal: International journal of toxicology20090101

Title: Potential impact of stress activated retrotransposons on genome evolution in a marine diatom.

Journal: BMC genomics20090101

Title: Mixed-valent Mn supertetrahedra and planar discs as enhanced magnetic coolers.

Journal: Journal of the American Chemical Society20080820

Title: Influence of additives including amine and hydroxyl groups on aqueous ammonia absorbent for CO2 capture.

Journal: The journal of physical chemistry. B20080410

Title: A new family of octanuclear Cu4Ln4 (Ln = Gd, Tb and Dy) spin clusters.

Journal: Dalton transactions (Cambridge, England : 2003)20080107

Title: Dirhodium(II)-catalyzed C-H amination reaction of (S)-3-(tert-butyldimethylsilyloxy)-2-methylpropyl carbamate: a facile preparation of optically active monoprotected 2-amino-2-methyl-1,3-propanediol.

Journal: Chemical & pharmaceutical bulletin20070901

Title: Mixed-valent cobalt spin clusters: a hexanuclear complex and a one-dimensional coordination polymer comprised of alternating hepta- and mononuclear fragments.

Journal: Inorganic chemistry20061030

Title: ATR-FTIR characterization of transport properties of benzoic acid ion-pairs in silicone membranes.

Journal: International journal of pharmaceutics20040928

Title: In vitro effect of a buffered chelating agent and neomycin or oxytetracycline on bacteria associated with diseases of fish.

Journal: Diseases of aquatic organisms20040611

Title: Electrospray mass spectrometry studies of macromolecules containing 1,3-oxazolidine moieties.

Journal: Rapid communications in mass spectrometry : RCM20040101

Title: Ultrathin-layer sodium dodecyl sulfate disc electrophoresis of proteins in the range from 10 to 220 kDa in homogeneous, low-concentrated polyacrylamide gels.

Journal: Electrophoresis20030701

Title: Effect of steric hindrance on carbon dioxide absorption into new amine solutions: thermodynamic and spectroscopic verification through solubility and NMR analysis.

Journal: Environmental science & technology20030415

Title: Function of mutant (G1144A) tissue-nonspecific ALP gene from hypophosphatasia.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research20021101

Title: Effect of a basic organic excipient on the dissolution of diclofenac salts.

Journal: Journal of pharmaceutical sciences20021001

Title: Preparation and characterisation of a range of diclofenac salts.

Journal: International journal of pharmaceutics20010911

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