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115-96-8,MFCD00000967
Catalog No.:AA000FIP

115-96-8 | Ethanol, 2-chloro-, 1,1',1''-phosphate

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1g
95%(GC)
in stock  
$24.00   $17.00
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25g
>93.0%(GC)
in stock  
$29.00   $20.00
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100g
>93.0%(GC)
in stock  
$90.00   $63.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000FIP
Chemical Name:
Ethanol, 2-chloro-, 1,1',1''-phosphate
CAS Number:
115-96-8
Molecular Formula:
C6H12Cl3O4P
Molecular Weight:
285.4898
MDL Number:
MFCD00000967
SMILES:
ClCCOP(=O)(OCCCl)OCCCl
NSC Number:
3213
Properties
Properties
 
BP:
330.0°C  
Form:
Liquid  
MP:
-51 °C  
Refractive Index:
n20/D 1.472(lit.)  
Solubility:
H2O: soluble7.82g/L  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
152  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
9  
XLogP3:
1.3  

Literature

Title: The combination of in silico and in vivo approaches for the investigation of disrupting effects of tris (2-chloroethyl) phosphate (TCEP) toward core receptors of zebrafish.

Journal: Chemosphere 20170201

Title: Investigation of the early-response genes in chemical-induced renal carcinogenicity for the prediction of chemical carcinogenicity in rats.

Journal: The Journal of toxicological sciences 20170101

Title: Developmental neurotoxicity of organophosphate flame retardants in early life stages of Japanese medaka (Oryzias latipes).

Journal: Environmental toxicology and chemistry 20161201

Title: Tris(2-chloroethyl)phosphate-induced cell growth arrest via attenuation of SIRT1-independent PI3K/Akt/mTOR pathway.

Journal: Journal of applied toxicology : JAT 20160701

Title: Differential modulation of neuro- and interrenal steroidogenesis of juvenile salmon by the organophosphates - tris(2-butoxyethyl)- and tris(2-cloroethyl) phosphate.

Journal: Environmental research 20160701

Title: Developmental exposure of zebrafish larvae to organophosphate flame retardants causes neurotoxicity.

Journal: Neurotoxicology and teratology 20160101

Title: Lipid peroxidation and oxidative stress responses in juvenile salmon exposed to waterborne levels of the organophosphate compounds tris(2-butoxyethyl)- and tris(2-chloroethyl) phosphates.

Journal: Journal of toxicology and environmental health. Part A 20160101

Title: TPP and TCEP induce oxidative stress and alter steroidogenesis in TM3 Leydig cells.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20151101

Title: Exposure of male mice to two kinds of organophosphate flame retardants (OPFRs) induced oxidative stress and endocrine disruption.

Journal: Environmental toxicology and pharmacology 20150701

Title: Affinities of organophosphate flame retardants to tumor suppressor gene p53: an integrated in vitro and in silico study.

Journal: Toxicology letters 20150122

Title: Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) and tris(2-chloro-2-ethyl)phosphate (TCEP).

Journal: Neurotoxicology and teratology 20150101

Title: Determination and prediction of the binding interaction between organophosphate flame retardants and p53.

Journal: Chemical research in toxicology 20141117

Title: The interaction between organic phosphate ester and p53: an integrated experimental and in silico approach.

Journal: Marine pollution bulletin 20140830

Title: Potential estrogenic effects of phosphorus-containing flame retardants.

Journal: Environmental science & technology 20140617

Title: Toxicity of TDCPP and TCEP on PC12 cell: changes in CAMKII, GAP43, tubulin and NF-H gene and protein levels.

Journal: Toxicology letters 20140616

Title: Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays.

Journal: Environmental science & technology 20130319

Title: Development of surrogate correlation models to predict trace organic contaminant oxidation and microbial inactivation during ozonation.

Journal: Water research 20121201

Title: Early zebrafish embryogenesis is susceptible to developmental TDCPP exposure.

Journal: Environmental health perspectives 20121101

Title: Cellular distribution of cell cycle-related molecules in the renal tubules of rats treated with renal carcinogens for 28 days: relationship between cell cycle aberration and carcinogenesis.

Journal: Archives of toxicology 20120901

Title: Occurrence of alternative flame retardants in indoor dust from New Zealand: indoor sources and human exposure assessment.

Journal: Chemosphere 20120901

Title: Complete detoxification of tris(2-chloroethyl) phosphate by two bacterial strains: Sphingobium sp. strain TCM1 and Xanthobacter autotrophicus strain GJ10.

Journal: Journal of bioscience and bioengineering 20120901

Title: Phosphorus flame retardants: properties, production, environmental occurrence, toxicity and analysis.

Journal: Chemosphere 20120801

Title: Occurrence and behavior of emerging contaminants in surface water and a restored wetland.

Journal: Chemosphere 20120801

Title: Levels and distributions of organophosphate flame retardants and plasticizers in sediment from Taihu Lake, China.

Journal: Environmental toxicology and chemistry 20120701

Title: Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish.

Journal: Aquatic toxicology (Amsterdam, Netherlands) 20120615

Title: Organophosphorus flame retardants and plasticizers in airborne particles over the Northern Pacific and Indian Ocean toward the Polar Regions: evidence for global occurrence.

Journal: Environmental science & technology 20120320

Title: Emerging pollutants in sewage, surface and drinking water in Galicia (NW Spain).

Journal: Chemosphere 20120301

Title: Determination of non-halogenated, chlorinated and brominated organophosphate flame retardants in herring gull eggs based on liquid chromatography-tandem quadrupole mass spectrometry.

Journal: Journal of chromatography. A 20120113

Title: Organophosphate and phthalate esters in standard reference material 2585 organic contaminants in house dust.

Journal: Analytical and bioanalytical chemistry 20120101

Title: Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells.

Journal: Toxicology and applied pharmacology 20111101

Title: [Simultaneous determination of six organophosphorous flame retardants in textiles by gas chromatography-tandem mass spectrometry combined with microwave assisted extraction].

Journal: Se pu = Chinese journal of chromatography 20110801

Title: Identification of flame retardants in polyurethane foam collected from baby products.

Journal: Environmental science & technology 20110615

Title: Reaction of tris(2-chloroethyl)phosphate with reduced sulfur species.

Journal: Chemosphere 20110501

Title: Attenuation of contaminants of emerging concern during surface-spreading aquifer recharge.

Journal: The Science of the total environment 20110215

Title: Occurrence and distribution of organophosphorus flame retardants and plasticizers in anthropogenically affected groundwater.

Journal: Journal of environmental monitoring : JEM 20110201

Title: Organophosphate ester flame retardant-induced acute intoxications in dogs.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20101201

Title: Intra- and interspecific nuclear ribosomal gene variation in the two Japanese Eothenomys species, E. andersoni and E. smithii.

Journal: Zoological science 20101201

Title: Human health risk assessment of pharmaceuticals in water: issues and challenges ahead.

Journal: International journal of environmental research and public health 20101101

Title: Occurrence and fate of organophosphorus flame retardants and plasticizers in urban and remote surface waters in Germany.

Journal: Water research 20100701

Title: Seasonal fluctuations of organophosphate concentrations in precipitation and storm water runoff.

Journal: Chemosphere 20100201

Title: Cellular effect evaluation of micropollutants using transporter functions of renal proximal tubule cells.

Journal: Chemosphere 20091101

Title: Pressurized liquid extraction of organophosphate triesters from sediment samples using aqueous solutions.

Journal: Journal of chromatography. A 20091016

Title: Waste-indicator and pharmaceutical compounds in landfill-leachate-affected ground water near Elkhart, Indiana, 2000-2002.

Journal: Bulletin of environmental contamination and toxicology 20090601

Title: Advanced oxidation kinetics of aqueous trialkyl phosphate flame retardants and plasticizers.

Journal: Environmental science & technology 20090415

Title: Indirect potable reuse: a sustainable water supply alternative.

Journal: International journal of environmental research and public health 20090301

Title: Respiratory and dermal exposure to organophosphorus flame retardants and tetrabromobisphenol A at five work environments.

Journal: Environmental science & technology 20090201

Title: Effect of tris-(2-chloroethyl)-phosphate (TCEP) at environmental concentration on the levels of cell cycle regulatory protein expression in primary cultured rabbit renal proximal tubule cells.

Journal: Chemosphere 20081201

Title: Photooxidation and subsequent biodegradability of recalcitrant tri-alkyl phosphates TCEP and TBP in water.

Journal: Water research 20081201

Title: Sources of endocrine-disrupting chemicals in urban wastewater, Oakland, CA.

Journal: The Science of the total environment 20081101

Title: A national reconnaissance for pharmaceuticals and other organic wastewater contaminants in the United States--II) untreated drinking water sources.

Journal: The Science of the total environment 20080901

Title: A national reconnaissance of pharmaceuticals and other organic wastewater contaminants in the United States--I) groundwater.

Journal: The Science of the total environment 20080901

Title: Enrichment and characterization of chlorinated organophosphate ester-degrading mixed bacterial cultures.

Journal: Journal of bioscience and bioengineering 20080701

Title: Differential response of Mono Mac 6, BEAS-2B, and Jurkat cells to indoor dust.

Journal: Environmental health perspectives 20070901

Title: [Evaluation of indoor air contaminants by means of reference and guideline values].

Journal: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 20070701

Title: [Determination of three organophosphorous flame retardants in textiles by gas chromatography].

Journal: Se pu = Chinese journal of chromatography 20070501

Title: Occurrence and removal of pharmaceuticals and endocrine disruptors in South Korean surface, drinking, and waste waters.

Journal: Water research 20070301

Title: Indoor organophosphate and polybrominated flame retardants in Tokyo.

Journal: Indoor air 20070201

Title: Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast.

Journal: Molecular systems biology 20070101

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Investigation of cytotoxic, genotoxic, mutagenic, and estrogenic effects of the flame retardants tris-(2-chloroethyl)-phosphate (TCEP) and tris-(2-chloropropyl)-phosphate (TCPP) in vitro.

Journal: Toxicology letters 20060220

Title: Elimination of organophosphate ester flame retardants and plasticizers in drinking water purification.

Journal: Water research 20060201

Title: Determination of phosphoric acid triesters in human plasma using solid-phase microextraction and gas chromatography coupled to inductively coupled plasma mass spectrometry.

Journal: Journal of chromatography. A 20060127

Title: Organophosphate triesters in indoor environments.

Journal: Journal of environmental monitoring : JEM 20050901

Title: Organophosphorus flame retardants and plasticizers in air from various indoor environments.

Journal: Journal of environmental monitoring : JEM 20050801

Title: Exposure to phthalate esters from indoor environment.

Journal: Journal of exposure analysis and environmental epidemiology 20041101

Title: Organophosphorus flame retardants and plasticisers in surface waters.

Journal: The Science of the total environment 20041001

Title: Organophosphate flame retardants and plasticisers in wastewater treatment plants.

Journal: Journal of environmental monitoring : JEM 20040701

Title: Screening of organophosphorus compounds and their distribution in various indoor environments.

Journal: Chemosphere 20031201

Title: Estimation of organophosphoric acid triesters in soft polyurethane foam using a concentrated sulfuric acid dissolution technique and gas chromatography with flame photometric detection.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20031201

Title: Monitoring of the three organophosphate esters TBP, TCEP and TBEP in river water and ground water (Oder, Germany).

Journal: Journal of environmental monitoring : JEM 20030401

Title: Degradation of organophosphoric esters in leachate from a sea-based solid waste disposal site.

Journal: Chemosphere 20020701

Title: Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999-2000: a national reconnaissance.

Journal: Environmental science & technology 20020315

Title: Chlorinated ethyl and isopropyl phosphoric acid triesters in the indoor environment--an inter-laboratory exposure study.

Journal: Indoor air 20010901

Title: NTP Toxicology and Carcinogenesis Studies of Tris(2-chloroethyl) Phosphate (CAS No. 115-96-8) in F344/N Rats and B6C3F1 Mice (Gavage Studies).

Journal: National Toxicology Program technical report series 19910501

Title: Metabolism of tris(2-chloroethyl) phosphate in rats and mice.

Journal: Drug metabolism and disposition: the biological fate of chemicals 19910101

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Tags:115-96-8 Molecular Formula|115-96-8 MDL|115-96-8 SMILES|115-96-8 Ethanol, 2-chloro-, 1,1',1''-phosphate