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115103-54-3,MFCD00865317
Catalog No.:AA000G86

115103-54-3 | Tiagabine

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Purity
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10mg
in stock  
$147.00   $103.00
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50mg
≥99%
in stock  
$627.00   $439.00
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100mg
≥99%
in stock  
$1,081.00   $757.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000G86
Chemical Name:
Tiagabine
CAS Number:
115103-54-3
Molecular Formula:
C20H25NO2S2
Molecular Weight:
375.5480
MDL Number:
MFCD00865317
SMILES:
OC(=O)[C@@H]1CCCN(C1)CCC=C(c1sccc1C)c1sccc1C
Properties
Computed Properties
 
Complexity:
474  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
2.7  

Literature

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Journal: Chemical research in toxicology 20150518

Title: Detection of 22 antiepileptic drugs by ultra-performance liquid chromatography coupled with tandem mass spectrometry applicable to routine therapeutic drug monitoring.

Journal: Biomedical chromatography : BMC 20121201

Title: Separate and combined effects of the GABA(B) agonist baclofen and Δ9-THC in humans discriminating Δ9-THC.

Journal: Drug and alcohol dependence 20121101

Title: The cost effectiveness of newer epilepsy treatments: a review of the literature on partial-onset seizures.

Journal: PharmacoEconomics 20121001

Title: Influence of sildenafil on the anticonvulsant action of selected antiepileptic drugs against pentylenetetrazole-induced clonic seizures in mice.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20120801

Title: Chronic tiagabine administration and aggressive responding in individuals with a history of substance abuse and antisocial behavior.

Journal: Journal of psychopharmacology (Oxford, England) 20120701

Title: Chemical properties of antiepileptic drugs (AEDs).

Journal: Advanced drug delivery reviews 20120701

Title: Does brain slices from pentylenetetrazole-kindled mice provide a more predictive screening model for antiepileptic drugs?

Journal: European journal of pharmacology 20120505

Title: Separate and combined effects of the GABA reuptake inhibitor tiagabine and Δ9-THC in humans discriminating Δ9-THC.

Journal: Drug and alcohol dependence 20120401

Title: Beneficial and adverse psychotropic effects of antiepileptic drugs in patients with epilepsy: a summary of prevalence, underlying mechanisms and data limitations.

Journal: CNS drugs 20120401

Title: Prevalence of treated epilepsy in Korea based on national health insurance data.

Journal: Journal of Korean medical science 20120301

Title: Identification of tiagabine degradation products using liquid chromatography with electrospray ionization multistage mass spectrometry and ultra-performance liquid chromatography/high-resolution mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20120215

Title: GABAA-positive modulator selective discriminative stimulus effects of 1,1,1-trichloroethane vapor.

Journal: Drug and alcohol dependence 20120201

Title: Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis.

Journal: Epilepsy research 20120201

Title: Neuromodulators for pain management in rheumatoid arthritis.

Journal: The Cochrane database of systematic reviews 20120118

Title: Choice of antiepileptic drugs for the elderly: possible drug interactions and adverse effects.

Journal: Expert opinion on drug metabolism & toxicology 20120101

Title: Recent developments in potential anxiolytic agents targeting GABAA/BzR complex or the translocator protein (18kDa) (TSPO).

Journal: Current topics in medicinal chemistry 20120101

Title: Two-drug antimicrobial chemotherapy: a mathematical model and experiments with Mycobacterium marinum.

Journal: PLoS pathogens 20120101

Title: GABAergic gene expression in postmortem hippocampus from alcoholics and cocaine addicts; corresponding findings in alcohol-naïve P and NP rats.

Journal: PloS one 20120101

Title: Combinational spinal GAD65 gene delivery and systemic GABA-mimetic treatment for modulation of spasticity.

Journal: PloS one 20120101

Title: Clinical utility of adjunctive retigabine in partial onset seizures in adults.

Journal: Therapeutics and clinical risk management 20120101

Title: [11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels.

Journal: PloS one 20120101

Title: Forty-year-old diabetic lady with tightness in lower limbs.

Journal: Annals of Indian Academy of Neurology 20120101

Title: Astrocytes convert network excitation to tonic inhibition of neurons.

Journal: BMC biology 20120101

Title: Perisynaptic GABA Receptors The Overzealous Protector.

Journal: Advances in pharmacological sciences 20120101

Title: Inhibitory action of antidepressants on mouse Betaine/GABA transporter (BGT1) heterologously expressed in cell cultures.

Journal: International journal of molecular sciences 20120101

Title: Tiagabine add-on for drug-resistant partial epilepsy.

Journal: The Cochrane database of systematic reviews 20120101

Title: A steered molecular dynamics study of binding and translocation processes in the GABA transporter.

Journal: PloS one 20120101

Title: Synthesis and pharmacological properties of new GABA uptake inhibitors.

Journal: Pharmacological reports : PR 20120101

Title: New developments in the treatment of partial-onset epilepsy.

Journal: Neuropsychiatric disease and treatment 20120101

Title: Tiagabine in the maintenance treatment of bipolar disorder.

Journal: The Cochrane database of systematic reviews 20111207

Title: Review of therapeutic options for adjuvant treatment of focal seizures in epilepsy: focus on lacosamide.

Journal: CNS drugs 20111205

Title: Transition to absence seizures and the role of GABA(A) receptors.

Journal: Epilepsy research 20111201

Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

Journal: PLoS computational biology 20111201

Title: Pharmacotherapy for anxiety disorders in children and adolescents.

Journal: Dialogues in clinical neuroscience 20111201

Title: Neuroimaging in anxiety disorders.

Journal: Dialogues in clinical neuroscience 20111201

Title: Experimental panic provocation in healthy man-a translational role in anti-panic drug development?

Journal: Dialogues in clinical neuroscience 20111201

Title: Nitric oxide, epileptic seizures, and action of antiepileptic drugs.

Journal: CNS & neurological disorders drug targets 20111101

Title: Blockade of GABA(B) receptors facilitates evoked neurotransmitter release at spinal dorsal horn synapse.

Journal: Neuroscience 20111013

Title: Treatment options in juvenile myoclonic epilepsy.

Journal: Current treatment options in neurology 20110801

Title: Antiepileptic drug discovery: does mechanism of action matter?

Journal: Epilepsy & behavior : E&B 20110801

Title: Gabapentin: An update of its pharmacological properties and therapeutic use in epilepsy.

Journal: Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110801

Title: Selective GABA transporter inhibitors tiagabine and EF1502 exhibit mechanistic differences in their ability to modulate the ataxia and anticonvulsant action of the extrasynaptic GABA(A) receptor agonist gaboxadol.

Journal: The Journal of pharmacology and experimental therapeutics 20110701

Title: Analyte and internal standard cross signal contributions and their impact on quantitation in LC-MS based bioanalysis.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110701

Title: Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: a systematic review and meta-analysis.

Journal: Epilepsia 20110701

Title: Deletion of the betaine-GABA transporter (BGT1; slc6a12) gene does not affect seizure thresholds of adult mice.

Journal: Epilepsy research 20110601

Title: The serotonin transporter is an exclusive client of the coat protein complex II (COPII) component SEC24C.

Journal: The Journal of biological chemistry 20110506

Title: Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats.

Journal: Psychopharmacology 20110501

Title: Non-neuronal, slow GABA signalling in the ventrobasal thalamus targets δ-subunit-containing GABA(A) receptors.

Journal: The European journal of neuroscience 20110401

Title: Strategies and practices in off-label marketing of pharmaceuticals: a retrospective analysis of whistleblower complaints.

Journal: PLoS medicine 20110401

Title: Efficacy of drug treatments for generalised anxiety disorder: systematic review and meta-analysis.

Journal: BMJ (Clinical research ed.) 20110311

Title: Risk factors for complications of drug-induced seizures.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20110301

Title: Depressogenic effects of medications: a review.

Journal: Dialogues in clinical neuroscience 20110301

Title: Analysis of electrical brain waves in neurotoxicology: γ-hydroxybutyrate.

Journal: Current neuropharmacology 20110301

Title: Pregabalin effect on steady-state pharmacokinetics of carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproate, and tiagabine.

Journal: Epilepsia 20110201

Title: An historical perspective on GABAergic drugs.

Journal: Future medicinal chemistry 20110201

Title: GABA transport inhibitors and seizure protection: the past and future.

Journal: Future medicinal chemistry 20110201

Title: Stereospecific synthesis and structure-activity relationships of unsymmetrical 4,4-diphenylbut-3-enyl derivatives of nipecotic acid as GAT-1 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20110101

Title: Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's disease.

Journal: PloS one 20110101

Title: The societal costs of insomnia.

Journal: Neuropsychiatric disease and treatment 20110101

Title: Treatment of alcohol dependence with low-dose topiramate: an open-label controlled study.

Journal: BMC psychiatry 20110101

Title: Caffeine and the anticonvulsant potency of antiepileptic drugs: experimental and clinical data.

Journal: Pharmacological reports : PR 20110101

Title: Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy.

Journal: Molecular pain 20110101

Title: Epilepsy (partial).

Journal: BMJ clinical evidence 20110101

Title: Virologic outcomes of HAART with concurrent use of cytochrome P450 enzyme-inducing antiepileptics: a retrospective case control study.

Journal: AIDS research and therapy 20110101

Title: Management of provoked seizure.

Journal: Annals of Indian Academy of Neurology 20110101

Title: Aromatase inhibitors and antiepileptic drugs: a computational systems biology analysis.

Journal: Reproductive biology and endocrinology : RB&E 20110101

Title: Suicidal behavior and antiepileptic drugs in epilepsy: analysis of the emerging evidence.

Journal: Drug, healthcare and patient safety 20110101

Title: Localization and Function of GABA Transporters GAT-1 and GAT-3 in the Basal Ganglia.

Journal: Frontiers in systems neuroscience 20110101

Title: Comparison of antinociceptive effect of the antiepileptic drug gabapentin to that of various dosage combinations of gabapentin with lamotrigine and topiramate in mice and rats.

Journal: Journal of neurosciences in rural practice 20110101

Title: Dysembryoplastic neuroepithelial tumor and probable sudden unexplained death in epilepsy: a case report.

Journal: Journal of medical case reports 20110101

Title: Identification of novel functional inhibitors of acid sphingomyelinase.

Journal: PloS one 20110101

Title: Augmentation of Tonic GABA(A) Inhibition in Absence Epilepsy: Therapeutic Value of Inverse Agonists at Extrasynaptic GABA(A) Receptors.

Journal: Advances in pharmacological sciences 20110101

Title: Treatment options for refractory and difficult to treat seizures: focus on vigabatrin.

Journal: Therapeutics and clinical risk management 20110101

Title: Treatment of generalized anxiety disorder: a comprehensive review of the literature for psychopharmacologic alternatives to newer antidepressants and benzodiazepines.

Journal: The primary care companion for CNS disorders 20110101

Title: A comprehensive review of the literature on epilepsy in selected countries in emerging markets.

Journal: Neuropsychiatric disease and treatment 20110101

Title: Novel pharmacotherapeutic treatments for cocaine addiction.

Journal: BMC medicine 20110101

Title: Effect of Gentiana olivieri on experimental epilepsy models.

Journal: Pharmacognosy magazine 20110101

Title: Design of a controlled release liquid formulation of lamotrigine.

Journal: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101

Title: GABA(A) positive modulator and NMDA antagonist-like discriminative stimulus effects of isoflurane vapor in mice.

Journal: Psychopharmacology 20101201

Title: Comparative anticonvulsant efficacy in the corneal kindled mouse model of partial epilepsy: Correlation with other seizure and epilepsy models.

Journal: Epilepsy research 20101201

Title: Use of antiepileptic drugs for hyperkinetic movement disorders.

Journal: Current neuropharmacology 20101201

Title: Is reduced ornithine-δ-aminotransferase activity the cause of vigabatrin-associated visual field defects?

Journal: Epilepsy research 20101101

Title: New users of the anticonvulsants gabapentin, lamotrigine, oxcarbazepine or tiagabine are at increased risk of suicidal acts compared with new users of topiramate.

Journal: Evidence-based mental health 20101101

Title: Effects of antiepileptic drugs on associative LTP-like plasticity in human motor cortex.

Journal: The European journal of neuroscience 20101001

Title: Rescuing the Corticostriatal Synaptic Disconnection in the R6/2 Mouse Model of Huntington's Disease: Exercise, Adenosine Receptors and Ampakines.

Journal: PLoS currents 20100920

Title: An open pilot study of tiagabine in alcohol dependence: tolerability and clinical effects.

Journal: Journal of psychopharmacology (Oxford, England) 20100901

Title: A possible role of the non-GAT1 GABA transporters in transfer of GABA from GABAergic to glutamatergic neurons in mouse cerebellar neuronal cultures.

Journal: Neurochemical research 20100901

Title: Do antiepileptic drugs increase the risk of suicidality in adult patients with epilepsy?: a critically appraised topic.

Journal: The neurologist 20100901

Title: Antiepileptic drug interactions - principles and clinical implications.

Journal: Current neuropharmacology 20100901

Title: A convergent approach to (R)-Tiagabine by a regio- and stereocontrolled hydroiodination of alkynes.

Journal: Organic & biomolecular chemistry 20100807

Title: Intrinsic activation of GABA(A) receptors suppresses epileptiform activity in the cerebral cortex of immature mice.

Journal: Epilepsia 20100801

Title: Use of antiepileptic drugs in epilepsy and the risk of self-harm or suicidal behavior.

Journal: Neurology 20100727

Title: Homology modelling of the GABA transporter and analysis of tiagabine binding.

Journal: ChemMedChem 20100705

Title: Epilepsy (partial).

Journal: BMJ clinical evidence 20100628

Title: Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship.

Journal: European journal of medicinal chemistry 20100601

Title: Predictors of suicidal ideation in people with epilepsy living in Korea.

Journal: Journal of clinical neurology (Seoul, Korea) 20100601

Title: Placebo effects in neurological diseases.

Journal: Journal of medicine and life 20100515

Title: Diverse antiepileptic drugs increase the ratio of background synaptic inhibition to excitation and decrease neuronal excitability in neurones of the rat entorhinal cortex in vitro.

Journal: Neuroscience 20100505

Title: Long-term anxiolytic and antidepressant-like behavioural effects of tiagabine, a selective GABA transporter-1 (GAT-1) inhibitor, coincide with a decrease in HPA system activity in C57BL/6 mice.

Journal: Journal of psychopharmacology (Oxford, England) 20100501

Title: [Antiepileptic drugs in North America].

Journal: Brain and nerve = Shinkei kenkyu no shinpo 20100501

Title: Anticonvulsant medications and the risk of suicide, attempted suicide, or violent death.

Journal: JAMA 20100414

Title: Loss of GABAergic interneurons in laminae I-III of the spinal cord dorsal horn contributes to reduced GABAergic tone and neuropathic pain after spinal cord injury.

Journal: Journal of neurotrauma 20100401

Title: Dose-related levetiracetam-induced reticulated drug eruption.

Journal: Journal of drugs in dermatology : JDD 20100401

Title: Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs.

Journal: Pharmacology & therapeutics 20100301

Title: Emergent complications of the newer anticonvulsants.

Journal: The Journal of emergency medicine 20100201

Title: Behavioral and cognitive effects of anti-epileptic drugs.

Journal: Discovery medicine 20100201

Title: Modulatory effects of neuropsychopharmaca on intracellular pH of hippocampal neurones in vitro.

Journal: British journal of pharmacology 20100101

Title: Drug interactions involving the new second- and third-generation antiepileptic drugs.

Journal: Expert review of neurotherapeutics 20100101

Title: Effects of Pharmacological Block of GABA(A) Receptors on Pallidal Neurons in Normal and Parkinsonian State.

Journal: Frontiers in cellular neuroscience 20100101

Title: [Therapeutic drug monitoring of tiagabine].

Journal: Therapie 20100101

Title: Assessing structure, function and druggability of major inhibitory neurotransmitter gamma-aminobutyrate symporter subtypes.

Journal: Current medicinal chemistry 20100101

Title: Review of topiramate for the treatment of epilepsy in elderly patients.

Journal: Clinical interventions in aging 20100101

Title: Medications acting on the GABA system in the treatment of alcoholic patients.

Journal: Current pharmaceutical design 20100101

Title: Efficacy, safety, and potential of extended-release lamotrigine in the treatment of epileptic patients.

Journal: Neuropsychiatric disease and treatment 20100101

Title: Management of refractory complex partial seizures: current state of the art.

Journal: Neuropsychiatric disease and treatment 20100101

Title: GABAB receptors in addiction and its treatment.

Journal: Advances in pharmacology (San Diego, Calif.) 20100101

Title: Selected Gamma Aminobutyric Acid (GABA) Esters may Provide Analgesia for Some Central Pain Conditions.

Journal: Perspectives in medicinal chemistry 20100101

Title: Assessing suicidal risk with antiepileptic drugs.

Journal: Neuropsychiatric disease and treatment 20100101

Title: GATMD: γ-aminobutyric acid transporter mutagenesis database.

Journal: Database : the journal of biological databases and curation 20100101

Title: Advances in epilepsy: new perspectives on new-onset epilepsy, comorbidities, and pharmacotherapy.

Journal: F1000 medicine reports 20100101

Title: Selected pharmacokinetic issues of the use of antiepileptic drugs and parenteral nutrition in critically ill patients.

Journal: Nutrition journal 20100101

Title: Antiepileptic drugs and suicidality.

Journal: Drug, healthcare and patient safety 20100101

Title: Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine.

Journal: Clinical pharmacology : advances and applications 20100101

Title: Changes in CCK-4 induced panic after treatment with the GABA-reuptake inhibitor tiagabine are associated with an increase in 3alpha,5alpha-tetrahydrodeoxycorticosterone concentrations.

Journal: Psychoneuroendocrinology 20091101

Title: Effects of the GABA-reuptake inhibitor tiagabine on panic and anxiety in patients with panic disorder.

Journal: Pharmacopsychiatry 20091101

Title: Synthesis and biological evaluation of 4-fluoroproline and 4-fluoropyrrolidine-2-acetic acid derivatives as new GABA uptake inhibitors.

Journal: Bioorganic & medicinal chemistry 20090915

Title: Pharmacologic treatment of impulsive aggression with antiepileptic drugs.

Journal: Current treatment options in neurology 20090901

Title: Basal ganglia neuroprotection with anticonvulsants after energy stress: a comparative study.

Journal: Metabolic brain disease 20090901

Title: Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice.

Journal: Methods and findings in experimental and clinical pharmacology 20090901

Title: Economic Evaluation of Add-on Levetiracetam for the Treatment of Refractory Partial Epilepsy in Korea.

Journal: Psychiatry investigation 20090901

Title: Synergistic interaction of gabapentin with tiagabine in the formalin test in mice: an isobolographic analysis.

Journal: European journal of pain (London, England) 20090801

Title: The GABA transporter 1 (SLC6A1): a novel candidate gene for anxiety disorders.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20090601

Title: Questionable tolerability of tiagabine in generalized anxiety disorder.

Journal: Journal of clinical psychopharmacology 20090601

Title: [Pharmacotherapy of substance dependence and withdrawal syndromes].

Journal: Therapeutische Umschau. Revue therapeutique 20090601

Title: Antiepileptic drug monotherapy: the initial approach in epilepsy management.

Journal: Current neuropharmacology 20090601

Title: Transitional polytherapy: tricks of the trade for monotherapy to monotherapy AED conversions.

Journal: Current neuropharmacology 20090601

Title: Truly 'rational' polytherapy: maximizing efficacy and minimizing drug interactions, drug load, and adverse effects.

Journal: Current neuropharmacology 20090601

Title: Minimizing AED adverse effects: improving quality of life in the interictal state in epilepsy care.

Journal: Current neuropharmacology 20090601

Title: Synaptic and extrasynaptic GABA transporters as targets for anti-epileptic drugs.

Journal: Journal of neurochemistry 20090501

Title: Pharmacodynamic and pharmacokinetic interaction profiles of levetiracetam in combination with gabapentin, tiagabine and vigabatrin in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis.

Journal: European journal of pharmacology 20090301

Title: [Empirical evidence for the use of anticonvulsants in personality disorders].

Journal: Fortschritte der Neurologie-Psychiatrie 20090301

Title: Tiagabine increases [11C]flumazenil binding in cortical brain regions in healthy control subjects.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090201

Title: For publication: Tiagabine in the discontinuation of long-term benzodiazepine use.

Journal: Psychiatry and clinical neurosciences 20090201

Title: Increase in tiagabine serum concentration with coadministration of gemfibrozil.

Journal: The Annals of pharmacotherapy 20090201

Title: Pharmacodynamic interactions between antiepileptic drugs: preclinical data based on isobolography.

Journal: Expert opinion on drug metabolism & toxicology 20090201

Title: Epilepsy.

Journal: BMJ clinical evidence 20090128

Title: A PET study of tiagabine treatment implicates ventral medial prefrontal cortex in generalized social anxiety disorder.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090101

Title: Retention rates of new antiepileptic drugs in localization-related epilepsy: a single-center study.

Journal: Acta neurologica Scandinavica 20090101

Title: Tiagabine augmentation to fluvoxamine-risperidone combination in the treatment of obsessive-compulsive disorder.

Journal: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101

Title: Stiff person syndrome.

Journal: Frontiers of neurology and neuroscience 20090101

Title: Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves.

Journal: Advances in medical sciences 20090101

Title: Managing epilepsy in women of childbearing age.

Journal: Drug safety 20090101

Title: Influence of agmatine on the protective action of numerous antiepileptic drugs against pentetrazole-induced seizures in mice.

Journal: Pharmacological reports : PR 20090101

Title: Synergistic interaction of gabapentin with tiagabine in the hot-plate test in mice: an isobolographic analysis.

Journal: Pharmacological reports : PR 20090101

Title: Gabapentin and tiagabine for social anxiety: a randomized, double-blind, crossover study of 8 adults.

Journal: Primary care companion to the Journal of clinical psychiatry 20090101

Title: Anticonvulsants in the treatment of major depressive disorder: an overview.

Journal: Harvard review of psychiatry 20090101

Title: Glutamate uptake triggers transporter-mediated GABA release from astrocytes.

Journal: PloS one 20090101

Title: Drugs associated with more suicidal ideations are also associated with more suicide attempts.

Journal: PloS one 20090101

Title: Treatment of refractory complex partial seizures: role of vigabatrin.

Journal: Neuropsychiatric disease and treatment 20090101

Title: Migraine: an overview.

Journal: The open neurology journal 20090101

Title: Effect of caffeine on the anticonvulsant effects of oxcarbazepine, lamotrigine and tiagabine in a mouse model of generalized tonic-clonic seizures.

Journal: Pharmacological reports : PR 20090101

Title: Neuroimaging in psychiatry: from bench to bedside.

Journal: Frontiers in human neuroscience 20090101

Title: Role of multidrug transporters in neurotherapeutics.

Journal: Annals of Indian Academy of Neurology 20090101

Title: ATP signalling in epilepsy.

Journal: Purinergic signalling 20081201

Title: Pregabalin for the management of partial epilepsy.

Journal: Neuropsychiatric disease and treatment 20081201

Title: Cross-sensitivity of skin rashes with antiepileptic drug use.

Journal: Neurology 20081104

Title: Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1-mGAT4.

Journal: European journal of medicinal chemistry 20081101

Title: Interactions of tiagabine with ethosuximide in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20081101

Title: Tiagabine for essential tremor: an open-label trial.

Journal: Movement disorders : official journal of the Movement Disorder Society 20081015

Title: On the presence of 3H-GABA uptake mechanism in bovine spermatozoa.

Journal: Animal reproduction science 20081001

Title: Optimizing prophylactic treatment of migraine: Subtypes and patient matching.

Journal: Therapeutics and clinical risk management 20081001

Title: [Seizure exacerbation caused by antiepileptic drugs].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080925

Title: Cognitive effects of antiepileptic drugs.

Journal: Journal of clinical neurology (Seoul, Korea) 20080901

Title: Metabolism of [1,6-(13)C]glucose and [U-(13)C]glutamine and depolarization induced GABA release in superfused mouse cerebral cortical mini-slices.

Journal: Neurochemical research 20080801

Title: Approaches to treatment of type 2 diabetes.

Journal: Diabetes care 20080801

Title: Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy.

Journal: PLoS medicine 20080801

Title: Tiagabine: let seizing dogs lie?

Journal: Emergency medicine Australasia : EMA 20080801

Title: Drug interactions between chemotherapeutic regimens and antiepileptics.

Journal: Clinical therapeutics 20080801

Title: Tiagabine: efficacy and safety in partial seizures - current status.

Journal: Neuropsychiatric disease and treatment 20080801

Title: Central nervous system adverse effects of new antiepileptic drugs. A meta-analysis of placebo-controlled studies.

Journal: Seizure 20080701

Title: Preoperative fMRI predicts memory decline following anterior temporal lobe resection.

Journal: Journal of neurology, neurosurgery, and psychiatry 20080601

Title: Short-term variations in response distribution to cortical stimulation.

Journal: Brain : a journal of neurology 20080601

Title: Tiagabine is neuroprotective in the N171-82Q and R6/2 mouse models of Huntington's disease.

Journal: Neurobiology of disease 20080601

Title: Tiagabine in adult patients with generalized anxiety disorder: results from 3 randomized, double-blind, placebo-controlled, parallel-group studies.

Journal: Journal of clinical psychopharmacology 20080601

Title: The search for medications to treat stimulant dependence.

Journal: Addiction science & clinical practice 20080601

Title: Acute and long-term treatment of mania.

Journal: Dialogues in clinical neuroscience 20080601

Title: Promising avenues of therapeutics for bipolar illness.

Journal: Dialogues in clinical neuroscience 20080601

Title: New treatments for cocaine dependence: a focused review.

Journal: The international journal of neuropsychopharmacology 20080501

Title: Interactions between tiagabine and conventional antiepileptic drugs in the rat model of complex partial seizures.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20080501

Title: Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats.

Journal: Psychopharmacology 20080501

Title: Induction of nuclear receptors and drug resistance in the brain microvascular endothelial cells treated with antiepileptic drugs.

Journal: Current neurovascular research 20080501

Title: Anticonvulsants for cocaine dependence.

Journal: The Cochrane database of systematic reviews 20080416

Title: Seizure-freedom with combination therapy in localization-related epilepsy.

Journal: Seizure 20080401

Title: Tiagabine, a GABA uptake inhibitor, attenuates 3-nitropropionic acid-induced alterations in various behavioral and biochemical parameters in rats.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20080401

Title: Clinical picture of EPM1-Unverricht-Lundborg disease.

Journal: Epilepsia 20080401

Title: Effects of acute tiagabine administration on aggressive responses of adult male parolees.

Journal: Journal of psychopharmacology (Oxford, England) 20080301

Title: Inhibition of the betaine-GABA transporter (mGAT2/BGT-1) modulates spontaneous electrographic bursting in the medial entorhinal cortex (mEC).

Journal: Epilepsy research 20080301

Title: Tiagabine treatment is associated with neurochemical, immune and behavioural alterations in the olfactory bulbectomized rat model of depression.

Journal: Pharmacopsychiatry 20080301

Title: Pregnancy, epilepsy, and anticonvulsants.

Journal: Dialogues in clinical neuroscience 20080301

Title: The effectiveness of anticonvulsants in psychiatric disorders.

Journal: Dialogues in clinical neuroscience 20080301

Title: Hypoalgesia in mice lacking GABA transporter subtype 1.

Journal: Journal of neuroscience research 20080201

Title: Inhibition of human aromatase complex (CYP19) by antiepileptic drugs.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20080201

Title: A review of ramelteon in the treatment of sleep disorders.

Journal: Neuropsychiatric disease and treatment 20080201

Title: Monotherapy for partial epilepsy: focus on levetiracetam.

Journal: Neuropsychiatric disease and treatment 20080201

Title: Antiepileptic drugs in non-epilepsy disorders: relations between mechanisms of action and clinical efficacy.

Journal: CNS drugs 20080101

Title: Reversal of GABA-mediated inhibition of the electrically and potassium chloride evoked [3H]-GABA release from rat substantia nigra slices by DL-3-hydroxy-3-phenyl pentanamide.

Journal: Arzneimittel-Forschung 20080101

Title: Status epilepticus due to tiagabine ingestion.

Journal: American journal of therapeutics 20080101

Title: Use of second-generation antiepileptic drugs in the pediatric population.

Journal: Paediatric drugs 20080101

Title: Depressive symptoms in epilepsy: prevalence, impact, aetiology, biological correlates and effect of treatment with antiepileptic drugs.

Journal: Drugs 20080101

Title: Fast homeostatic plasticity of inhibition via activity-dependent vesicular filling.

Journal: PloS one 20080101

Title: Pilot study of lorazepam and tiagabine effects on sleep, motor learning, and impulsivity in cocaine abstinence.

Journal: The American journal of drug and alcohol abuse 20080101

Title: GABI-balance--a non-interventional observational study on the effectiveness of tiagabine in add-on therapy in partial epilepsy.

Journal: Neurologia i neurochirurgia polska 20080101

Title: Seizure control in patients with epilepsy: the physician vs. medication factors.

Journal: BMC health services research 20080101

Title: [Endocrine effects of antiepileptic drugs].

Journal: Przeglad lekarski 20080101

Title: [Effects of antiepileptic drugs on immune system].

Journal: Przeglad lekarski 20080101

Title: Effects of new antiepileptic drugs and progabide on the mitogen-induced proliferative activity of mouse splenocytes.

Journal: Pharmacological reports : PR 20080101

Title: Effect of cocaine on responsiveness of alpha(1)-adrenergic receptors in rat cerebral cortex: modulation by GABA-mimetic drugs.

Journal: Pharmacological reports : PR 20080101

Title: Ocular adverse effects of Topiramate: Two case reports.

Journal: Indian journal of pharmacology 20080101

Title: [Treatment of epilepsy with third-line antiepileptic drugs: felbamate, tiagabine, and sulthiame].

Journal: Der Nervenarzt 20071201

Title: A double-blind, placebo-controlled trial of tiagabine for the treatment of cocaine dependence.

Journal: Drug and alcohol dependence 20071201

Title: Deliberate self-poisoning with tiagabine: an unusual toxidrome.

Journal: Emergency medicine Australasia : EMA 20071201

Title: Therapeutic options and challenges for substances of abuse.

Journal: Dialogues in clinical neuroscience 20071201

Title: Management of epilepsy in the elderly.

Journal: Neuropsychiatric disease and treatment 20071201

Title: Treatment of drop attacks in Coffin-Lowry syndrome with the use of sodium oxybate.

Journal: Pediatric neurology 20071101

Title: Tiagabine and exacerbation of essential tremor.

Journal: Movement disorders : official journal of the Movement Disorder Society 20071031

Title: Neurochemical regulation of sleep.

Journal: Journal of psychiatric research 20071001

Title: Timed pentylenetetrazol infusion test: a comparative analysis with s.c.PTZ and MES models of anticonvulsant screening in mice.

Journal: Seizure 20071001

Title: Homeostatic plasticity of GABAergic synaptic transmission in mice lacking GAT1.

Journal: Biochemical and biophysical research communications 20070921

Title: [Rational combination therapy in epilepsy. II. Clinical and pharmacological aspects].

Journal: Revista de neurologia 20070801

Title: Antiepileptic drugs for the treatment of post-traumatic stress disorder.

Journal: Current psychiatry reports 20070801

Title: Attenuation of cocaine-seeking by GABA B receptor agonists baclofen and CGP44532 but not the GABA reuptake inhibitor tiagabine in baboons.

Journal: Drug and alcohol dependence 20070710

Title: Reduced anxiety and depression-like behaviors in mice lacking GABA transporter subtype 1.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070701

Title: Synthesis and biological evaluation of (R)-N-(diarylmethylthio/sulfinyl)ethyl/propyl-piperidine-3-carboxylic acid hydrochlorides as novel GABA uptake inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20070701

Title: Seizure-free outcome in randomized add-on trials of the new antiepileptic drugs.

Journal: Epilepsia 20070701

Title: Tiagabine for social anxiety disorder.

Journal: Human psychopharmacology 20070601

Title: The role of anticonvulsant drugs in anxiety disorders: a critical review of the evidence.

Journal: Journal of clinical psychopharmacology 20070601

Title: New developments in the pharmacotherapy of cocaine abuse.

Journal: Addiction biology 20070601

Title: Status gelasticus associated with levetiracetam as add-on treatment.

Journal: Epileptic disorders : international epilepsy journal with videotape 20070601

Title: Antiepileptic drugs and visual function.

Journal: Pediatric neurology 20070601

Title: Comparison and predictors of rash associated with 15 antiepileptic drugs.

Journal: Neurology 20070515

Title: Diverse effects of GABA-mimetic drugs on cocaine-evoked self-administration and discriminative stimulus effects in rats.

Journal: Psychopharmacology 20070501

Title: Tiagabine does not attenuate alcohol-induced activation of the human reward system.

Journal: Psychopharmacology 20070501

Title: A new look at the second-generation antiepileptic drugs: a decade of experience.

Journal: The neurologist 20070501

Title: Synaptic activation of GABA(B) receptors regulates neuronal network activity and entrainment.

Journal: The European journal of neuroscience 20070501

Title: Absence seizures are reduced by the enhancement of GABA-ergic inhibition in the hippocampus in WAG/Rij rats.

Journal: Neuroscience letters 20070406

Title: New therapies for ataxia-telangiectasia.

Journal: Archives of neurology 20070401

Title: Tiagabine-induced non-convulsive status epilepticus in a patient without history of epilepsy.

Journal: Neurosciences (Riyadh, Saudi Arabia) 20070401

Title: Isobolographic characterization of interactions between vigabatrin and tiagabine in two experimental models of epilepsy.

Journal: Progress in neuro-psychopharmacology & biological psychiatry 20070330

Title: Topiramate reduces ethanol consumption by C57BL/6 mice.

Journal: Synapse (New York, N.Y.) 20070301

Title: Gaboxadol, a selective extrasynaptic GABA(A) agonist, does not generalise to other sleep-enhancing drugs: a rat drug discrimination study.

Journal: Neuropharmacology 20070301

Title: Anticonvulsants in sports: ethical considerations.

Journal: Epilepsy & behavior : E&B 20070301

Title: Long-term retention rates of new antiepileptic drugs in adults with chronic epilepsy and learning disability.

Journal: Epilepsy & behavior : E&B 20070301

Title: Depression in epilepsy: phenomenology, diagnosis and management.

Journal: Epileptic disorders : international epilepsy journal with videotape 20070301

Title: Clinical efficacy of gabapentin versus tiagabine for reducing cocaine use among cocaine dependent methadone-treated patients.

Journal: Drug and alcohol dependence 20070223

Title: Reduced aggression in mice lacking GABA transporter subtype 1.

Journal: Journal of neuroscience research 20070215

Title: Psychiatric and behavioral side effects of the newer antiepileptic drugs in adults with epilepsy.

Journal: Epilepsy & behavior : E&B 20070201

Title: Effects of antiepileptic drugs on learning as assessed by a repeated acquisition of response sequences task in rats.

Journal: Epilepsy & behavior : E&B 20070201

Title: The efficacy and tolerability of tiagabine in adult patients with post-traumatic stress disorder.

Journal: Journal of clinical psychopharmacology 20070201

Title: Tiagabine-induced myoclonic status epilepticus in a nonepileptic patient.

Journal: Neurology 20070123

Title: Novel anticonvulsant drugs.

Journal: Pharmacology & therapeutics 20070101

Title: High-affinity GABA uptake and GABA-metabolizing enzymes in pig forebrain white matter: a quantitative study.

Journal: Neurochemistry international 20070101

Title: Progress report on new antiepileptic drugs: a summary of the Eigth Eilat Conference (EILAT VIII).

Journal: Epilepsy research 20070101

Title: Targets for antiepileptic drugs in the synapse.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20070101

Title: Discovery of antiepileptic drugs.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101

Title: Use of antiepileptic drugs for nonepileptic conditions: psychiatric disorders and chronic pain.

Journal: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101

Title: Suicidality and antiepileptic drugs: is there a link?

Journal: Drug safety 20070101

Title: Current approaches to the pharmacologic treatment of anxiety disorders.

Journal: Psychopharmacology bulletin 20070101

Title: Second-generation antiepileptic drugs' impact on balance: a meta-analysis.

Journal: Mayo Clinic proceedings 20070101

Title: Pharmacokinetics and therapeutic drug monitoring of newer antiepileptic drugs during pregnancy and the puerperium.

Journal: Clinical pharmacokinetics 20070101

Title: Pharmacotherapy of dual substance abuse and dependence.

Journal: CNS drugs 20070101

Title: An open-label study to evaluate switching from an SSRI or SNRI to tiagabine to alleviate antidepressant-induced sexual dysfunction in generalized anxiety disorder.

Journal: Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20070101

Title: Neurobiology of memory and anxiety: from genes to behavior.

Journal: Neural plasticity 20070101

Title: Negative effects of antiepileptic drugs on mood in patients with epilepsy.

Journal: Drug safety 20070101

Title: Modulatory effects of nitric oxide-active drugs on the anticonvulsant activity of lamotrigine in an experimental model of partial complex epilepsy in the rat.

Journal: BMC neuroscience 20070101

Title: Influence of tiagabine on the antinociceptive action of morphine, metamizole and indomethacin in mice.

Journal: Acta poloniae pharmaceutica 20070101

Title: [Tiagabine overdose--report of two cases].

Journal: Przeglad lekarski 20070101

Title: Is tiagabine helpful in generalized anxiety disorder?

Journal: Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20070101

Title: Effect of NG-nitro-L-arginine on the anticonvulsant action of four second-generation antiepileptic drugs in pentetrazole-induced clonic seizures in mice.

Journal: Pharmacological reports : PR 20070101

Title: Sequence variation and linkage disequilibrium in the GABA transporter-1 gene (SLC6A1) in five populations: implications for pharmacogenetic research.

Journal: BMC genetics 20070101

Title: An open-label study of tiagabine in panic disorder.

Journal: Psychopharmacology bulletin 20070101

Title: Effects of some new antiepileptic drugs and progabide on glucocorticoid receptor-mediated gene transcription in LMCAT cells.

Journal: Pharmacological reports : PR 20070101

Title: [New hypnotics: perspectives from sleep physiology].

Journal: Vertex (Buenos Aires, Argentina) 20070101

Title: [Caffeine and antiepileptic drugs: experimental and clinical data].

Journal: Przeglad lekarski 20070101

Title: Optimizing therapy of seizures in women who use oral contraceptives.

Journal: Neurology 20061226

Title: The ethics of excluding women who become pregnant while participating in clinical trials of anti-epileptic medications.

Journal: Seizure 20061201

Title: Rofecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor potentiates the anticonvulsant activity of tiagabine against pentylenetetrazol-induced convulsions in mice.

Journal: Inflammopharmacology 20061201

Title: Seizures in a pediatric patient with a tiagabine overdose.

Journal: Journal of medical toxicology : official journal of the American College of Medical Toxicology 20061201

Title: Psychopharmacology of topiramate: from epilepsy to bipolar disorder.

Journal: Neuropsychiatric disease and treatment 20061201

Title: Tiagabine-induced nonconvulsive status epilepticus in an adolescent without epilepsy.

Journal: Neurology 20061024

Title: [Adult-onset ataxia-telangiectasia. A clinical and therapeutic observation].

Journal: Neurologia (Barcelona, Spain) 20061001

Title: Tiagabine in anxiety disorders.

Journal: Expert opinion on pharmacotherapy 20061001

Title: Effect of the administration of tiagabine and gabapentin on rabbit electroencephalogram activity.

Journal: The Journal of pharmacy and pharmacology 20061001

Title: Altered cortico-striatal synaptic plasticity and related behavioural impairments in reeler mice.

Journal: The European journal of neuroscience 20061001

Title: Comparison of the efficacy and tolerability of new antiepileptic drugs: what can we learn from long-term studies?

Journal: Acta neurologica Scandinavica 20060901

Title: Tiagabine withdrawal-emergent mania.

Journal: The Australian and New Zealand journal of psychiatry 20060801

Title: Tiagabine in the treatment of acute affective episodes in bipolar disorder: efficacy and acceptability.

Journal: The Cochrane database of systematic reviews 20060719

Title: Tiagabine in the maintenance treatment of bipolar disorders.

Journal: The Cochrane database of systematic reviews 20060719

Title: Enhancement of brain kynurenic acid production by anticonvulsants--novel mechanism of antiepileptic activity?

Journal: European journal of pharmacology 20060717

Title: Various GABA-mimetic drugs differently affect cocaine-evoked hyperlocomotion and sensitization.

Journal: European journal of pharmacology 20060717

Title: Comparison of the cognitive effects of tiagabine and carbamazepine as monotherapy in newly diagnosed adult patients with partial epilepsy: pooled analysis of two long-term, randomized, follow-up studies.

Journal: Epilepsia 20060701

Title: Tiagabine and vigabatrin reduce the severity of NMDA-induced excitotoxicity in chick retina.

Journal: Experimental brain research 20060601

Title: Long-term effects of tiagabine monotherapy on cognition and mood in adult patients with chronic partial epilepsy.

Journal: Epilepsy & behavior : E&B 20060601

Title: The use of tiagabine in pediatric spasticity management.

Journal: Developmental medicine and child neurology 20060601

Title: Age-correlated decline in [3H]tiagabine binding to GAT-1 in human frontal cortex.

Journal: Aging clinical and experimental research 20060601

Title: Cognitive Effects of Low-dose Topiramate Compared with Oxcarbazepine in Epilepsy Patients.

Journal: Journal of clinical neurology (Seoul, Korea) 20060601

Title: Pregabalin exerts oppositional effects on different inhibitory circuits in human motor cortex: a double-blind, placebo-controlled transcranial magnetic stimulation study.

Journal: Epilepsia 20060501

Title: Transient athetosis induced by tiagabine.

Journal: Epilepsia 20060401

Title: Tiagabine is associated with sustained attention during sleep restriction: evidence for the value of slow-wave sleep enhancement?

Journal: Sleep 20060401

Title: Tiagabine enhances slow wave sleep and sleep maintenance in primary insomnia.

Journal: Sleep medicine 20060301

Title: Clinically relevant drug interactions with antiepileptic drugs.

Journal: British journal of clinical pharmacology 20060301

Title: Anticonvulsants in the treatment of bipolar mania.

Journal: Expert opinion on pharmacotherapy 20060301

Title: Emerging pharmacological strategies in the fight against cocaine addiction.

Journal: Expert opinion on emerging drugs 20060301

Title: The clinical effectiveness and cost-effectiveness of newer drugs for children with epilepsy. A systematic review.

Journal: Health technology assessment (Winchester, England) 20060301

Title: Effect of tiagabine on sleep in elderly subjects with primary insomnia: a randomized, double-blind, placebo-controlled study.

Journal: Sleep 20060301

Title: Seizure activity and off-label use of tiagabine.

Journal: The New England journal of medicine 20060216

Title: Tiagabine increases slow-wave sleep in a dose-dependent fashion without affecting traditional efficacy measures in adults with primary insomnia.

Journal: Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20060115

Title: Design, synthesis, and biological evaluation of the N-diarylalkenyl-piperidinecarboxylic acid derivatives as GABA uptake inhibitors (I).

Journal: Bioorganic & medicinal chemistry letters 20060101

Title: Tiagabine for posttraumatic stress disorder: effects of open-label and double-blind discontinuation treatment.

Journal: Psychopharmacology 20060101

Title: Neurotransmitter transporters and their impact on the development of psychopharmacology.

Journal: British journal of pharmacology 20060101

Title: Open-label tiagabine monotherapy for major depressive disorder with anxiety.

Journal: The Journal of clinical psychiatry 20060101

Title: Interactions between antiepileptic and antipsychotic drugs.

Journal: Drug safety 20060101

Title: Clinical pharmacokinetics of new-generation antiepileptic drugs at the extremes of age.

Journal: Clinical pharmacokinetics 20060101

Title: Glial modulation of GABAergic and glutamat ergic neurotransmission.

Journal: Current topics in medicinal chemistry 20060101

Title: Intrahemispheric dysfunction in primary motor cortex without corpus callosum: a transcranial magnetic stimulation study.

Journal: BMC neurology 20060101

Title: Structure-activity relationships of selective GABA uptake inhibitors.

Journal: Current topics in medicinal chemistry 20060101

Title: Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?

Journal: Clinical pharmacokinetics 20060101

Title: Structure-activity relationship and pharmacology of gamma-aminobutyric acid (GABA) transport inhibitors.

Journal: Advances in pharmacology (San Diego, Calif.) 20060101

Title: A comparative study on the cost of new antibiotics and drugs of other therapeutic categories.

Journal: PloS one 20060101

Title: Effect of combined administration of ethanol and tiagabine on rabbit EEG.

Journal: Pharmacological reports : PR 20060101

Title: Effects of GABAergic modulators on food and cocaine self-administration in baboons.

Journal: Drug and alcohol dependence 20051212

Title: Effects of antiepileptic drugs on attention as assessed by a five-choice serial reaction time task in rats.

Journal: Epilepsy & behavior : E&B 20051201

Title: Color vision and contrast sensitivity in epilepsy patients treated with initial tiagabine monotherapy.

Journal: Epilepsy research 20051201

Title: Alteration of thyroid hormone homeostasis by antiepileptic drugs in humans: involvement of glucuronosyltransferase induction.

Journal: European journal of clinical pharmacology 20051201

Title: Pharmacokinetic variability of new antiepileptic drugs at different ages.

Journal: Therapeutic drug monitoring 20051201

Title: The pharmacokinetics and interactions of new antiepileptic drugs: an overview.

Journal: Therapeutic drug monitoring 20051201

Title: Sleep and psychiatry.

Journal: Dialogues in clinical neuroscience 20051201

Title: Sleep disturbances, psychiatric disorders, and psychotropic drugs.

Journal: Dialogues in clinical neuroscience 20051201

Title: A retrospective chart review comparing tiagabine and benzodiazepines for the treatment of alcohol withdrawal.

Journal: Journal of psychoactive drugs 20051201

Title: New medications for the treatment of cocaine dependence.

Journal: Psychiatry (Edgmont (Pa. : Township)) 20051201

Title: Tiagabine affects the subjective responses to cocaine in humans.

Journal: Pharmacology, biochemistry, and behavior 20051101

Title: The selective GABA reuptake inhibitor tiagabine for the treatment of generalized anxiety disorder: results of a placebo-controlled study.

Journal: The Journal of clinical psychiatry 20051101

Title: Antidystonic efficacy of gamma-aminobutyric acid uptake inhibitors in the dtsz mutant.

Journal: European journal of pharmacology 20051003

Title: Medications development: successes and challenges.

Journal: Pharmacology & therapeutics 20051001

Title: Status epilepticus and tiagabine therapy revisited.

Journal: Epilepsia 20051001

Title: Recent pharmacologic updates.

Journal: Journal of child and adolescent psychopharmacology 20051001

Title: Effects of tiagabine in combination with intravenous nicotine in overnight abstinent smokers.

Journal: Psychopharmacology 20050901

Title: Control of refractory status epilepticus precipitated by anticonvulsant withdrawal using left vagal nerve stimulation: a case report.

Journal: Surgical neurology 20050801

Title: Isobolographic characterisation of interactions among selected newer antiepileptic drugs in the mouse pentylenetetrazole-induced seizure model.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20050701

Title: Tiagabine reduces ethanol reward in C57BL/6 mice under acute and chronic administration regimens.

Journal: Synapse (New York, N.Y.) 20050601

Title: Pharmacological and histological characterisation of nicotine-kindled seizures in mice.

Journal: Neuropharmacology 20050601

Title: Comparison of the effects of anticonvulsant drugs with diverse mechanisms of action in the formalin test in rats.

Journal: Neuropharmacology 20050601

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Dose-response effects of tiagabine on the sleep of older adults.

Journal: Sleep 20050601

Title: Efficacy and cognitive side effects of tiagabine and topiramate in patients with epilepsy.

Journal: Epilepsy & behavior : E&B 20050501

Title: Selective GABAergic treatment for panic? Investigations in experimental panic induction and panic disorder.

Journal: Journal of psychiatry & neuroscience : JPN 20050501

Title: Pharmacotherapy and other treatments for cocaine abuse and dependence.

Journal: Current opinion in psychiatry 20050501

Title: Tiagabine for treatment of bipolar disorder with severe anxiety.

Journal: Psychiatry (Edgmont (Pa. : Township)) 20050501

Title: Clinical effectiveness, tolerability and cost-effectiveness of newer drugs for epilepsy in adults: a systematic review and economic evaluation.

Journal: Health technology assessment (Winchester, England) 20050401

Title: GABA transporter deficiency causes tremor, ataxia, nervousness, and increased GABA-induced tonic conductance in cerebellum.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050323

Title: Tiagabine as add-on therapy may be more effective with valproic acid--open label, multicentre study of patients with focal epilepsy.

Journal: European journal of neurology 20050301

Title: A randomised open-label study of tiagabine given two or three times daily in refractory epilepsy.

Journal: Seizure 20050301

Title: A placebo-controlled screening trial of tiagabine, sertraline and donepezil as cocaine dependence treatments.

Journal: Addiction (Abingdon, England) 20050301

Title: Cocaine Rapid Efficacy Screening Trials (CREST): lessons learned.

Journal: Addiction (Abingdon, England) 20050301

Title: Cocaine Rapid Efficacy Screening Trial (CREST): a paradigm for the controlled evaluation of candidate medications for cocaine dependence.

Journal: Addiction (Abingdon, England) 20050301

Title: First demonstration of a functional role for central nervous system betaine/{gamma}-aminobutyric acid transporter (mGAT2) based on synergistic anticonvulsant action among inhibitors of mGAT1 and mGAT2.

Journal: The Journal of pharmacology and experimental therapeutics 20050201

Title: Tiagabine-induced generalised non convulsive status epilepticus in patients with lesional focal epilepsy.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20050201

Title: Trauma, resilience and saliostasis: effects of treatment in post-traumatic stress disorder.

Journal: International clinical psychopharmacology 20050101

Title: Preliminary study on the efficacy and tolerability of newer anticonvulsants in a population of epileptic patients.

Journal: Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101

Title: Mechanisms of action of antiepileptic drugs.

Journal: Current topics in medicinal chemistry 20050101

Title: Novel approaches to the treatment of cocaine addiction.

Journal: CNS drugs 20050101

Title: Meta-analysis and indirect comparisons of levetiracetam with other second-generation antiepileptic drugs in partial epilepsy.

Journal: Clinical neuropharmacology 20050101

Title: Antiepileptic action induced by a combination of vigabatrin and tiagabine.

Journal: Neuroscience 20050101

Title: Bipolar mixed states and their treatment.

Journal: Expert review of neurotherapeutics 20050101

Title: Bupropion-induced convulsions: preclinical evaluation of antiepileptic drugs.

Journal: Epilepsy research 20050101

Title: Tiagabine for rage, aggression, and anxiety.

Journal: The Journal of neuropsychiatry and clinical neurosciences 20050101

Title: Tiagabine and gabapentin for the management of chronic pain.

Journal: The Clinical journal of pain 20050101

Title: Antiepileptic drugs in mood-disordered patients.

Journal: Epilepsia 20050101

Title: Ion channels and epilepsy.

Journal: Current pharmaceutical design 20050101

Title: New antiepileptic drugs--an overview.

Journal: Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101

Title: Saccadic eye velocity after selective GABAergic treatment with tiagabine in healthy volunteers.

Journal: Neuropsychobiology 20050101

Title: Functional GABA uptake at inhibitory synapses in CA1 of chronically epileptic rats.

Journal: Epilepsy research 20050101

Title: Tiagabine may reduce bruxism and associated temporomandibular joint pain.

Journal: Anesthesia progress 20050101

Title: Practical management issues for idiopathic generalized epilepsies.

Journal: Epilepsia 20050101

Title: Depression of extra-cellular GABA and increase of NMDA-induced nitric oxide following acute intra-nuclear administration of alcohol in the cerebellar nuclei of the rat.

Journal: Cerebellum (London, England) 20050101

Title: [GEOS (Gabitril Epilepsy Observational Study) -- Polish results of the international study of tiagabine in partial epilepsy].

Journal: Neurologia i neurochirurgia polska 20050101

Title: Role of opioidergic mechanisms and GABA uptake inhibition in the heroin-induced discriminative stimulus effects in rats.

Journal: Pharmacological reports : PR 20050101

Title: An open-label study of tiagabine as augmentation therapy for anxiety.

Journal: Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20050101

Title: Retrospective evaluation of tiagabine overdose.

Journal: Clinical toxicology (Philadelphia, Pa.) 20050101

Title: Tiagabine overdose: a case of status epilepticus in a non-epileptic patient.

Journal: Clinical toxicology (Philadelphia, Pa.) 20050101

Title: [Current pharmacotherapy of epilepsy in adults].

Journal: Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg 20050101

Title: The pharmacokinetic inter-relationship of tiagabine in blood, cerebrospinal fluid and brain extracellular fluid (frontal cortex and hippocampus).

Journal: Seizure 20041201

Title: Effects of antiepileptic drugs on working memory as assessed by spatial alternation performance in rats.

Journal: Epilepsy & behavior : E&B 20041201

Title: Novel secoergoline derivatives inhibit both GABA and glutamate uptake in rat brain homogenates: synthesis, in vitro pharmacology, and modeling.

Journal: Journal of medicinal chemistry 20041104

Title: Fracture risk associated with use of antiepileptic drugs.

Journal: Epilepsia 20041101

Title: GABA transporters as drug targets for modulation of GABAergic activity.

Journal: Biochemical pharmacology 20041015

Title: Acute administration of the GABA reuptake inhibitor tiagabine does not alter the effects of oral cocaine in humans.

Journal: Drug and alcohol dependence 20041005

Title: Treating refractory epilepsy with tiagabine: clinical experience.

Journal: Seizure 20041001

Title: Efficacy and tolerability of the new antiepileptic drugs: comparison of two recent guidelines.

Journal: The Lancet. Neurology 20041001

Title: Intentional overdose with tiagabine: an unusual clinical presentation.

Journal: The Journal of emergency medicine 20041001

Title: Behavioural correlates of an altered balance between synaptic and extrasynaptic GABAAergic inhibition in a mouse model.

Journal: The European journal of neuroscience 20041001

Title: [Progressive encephalomyelitis with rigidity responsive to gabapentin: a pharmacological update].

Journal: Neurologia (Barcelona, Spain) 20041001

Title: Alpha 5 subunit-containing GABAA receptors affect the dynamic range of mouse hippocampal kainate-induced gamma frequency oscillations in vitro.

Journal: The Journal of physiology 20040915

Title: Acute vigabatrin retinotoxicity in albino rats depends on light but not GABA.

Journal: Epilepsia 20040901

Title: Vigabatrin and tiagabine might have antipanic properties.

Journal: Journal of psychopharmacology (Oxford, England) 20040901

Title: Drug selection for the newly diagnosed patient: when is a new generation antiepileptic drug indicated?

Journal: Journal of neurology 20040901

Title: Side effects of antiepileptics--a review.

Journal: Pain practice : the official journal of World Institute of Pain 20040901

Title: GABAergic neurotransmission in globus pallidus and its involvement in neurologic disorders.

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20040825

Title: Pharmacodynamic interaction studies with topiramate in the pentylenetetrazol and maximal electroshock seizure models.

Journal: Seizure 20040701

Title: [Anticonvulsant hypersensitivity syndrome with severe repercussions in the skin and kidneys due to carbamazepine].

Journal: Revista de neurologia 20040601

Title: [Treatment protocol for long-term anti-epilepsy drugs in adults with refractory partial epilepsy].

Journal: Revue neurologique 20040601

Title: New pharmacotherapies for pediatric seizures.

Journal: Pediatric annals 20040601

Title: Efficacy and tolerability of the new antiepileptic drugs, I: Treatment of new-onset epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.

Journal: Epilepsia 20040501

Title: Efficacy and tolerability of the new antiepileptic drugs, II: Treatment of refractory epilepsy: report of the TTA and QSS Subcommittees of the American Academy of Neurology and the American Epilepsy Society.

Journal: Epilepsia 20040501

Title: Pharmacodynamic analysis of the anticonvulsant effects of tiagabine and lamotrigine in combination in the rat.

Journal: Epilepsia 20040501

Title: Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

Journal: Neurology 20040427

Title: Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

Journal: Neurology 20040427

Title: Isobolographic profile of interactions between tiagabine and gabapentin: a preclinical study.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20040401

Title: Understanding co-morbidities affecting children with epilepsy.

Journal: Neurology 20040309

Title: Interaction between anticonvulsants and human placental carnitine transporter.

Journal: Epilepsia 20040301

Title: Anticonvulsants as anxiolytics, part 1: tiagabine and other anticonvulsants with actions on GABA.

Journal: The Journal of clinical psychiatry 20040301

Title: The effect of antiepileptic drugs on visual performance.

Journal: Seizure 20040301

Title: The new antiepileptic drugs: scientific review.

Journal: JAMA 20040204

Title: Mood effects of antiepileptic drugs.

Journal: Epilepsy & behavior : E&B 20040201

Title: Coactivation of GABA(A) and GABA(B) receptor results in neuroprotection during in vitro ischemia.

Journal: Stroke 20040201

Title: Tiagabine for treating painful tonic spasms in multiple sclerosis: a pilot study.

Journal: Journal of neurology, neurosurgery, and psychiatry 20040201

Title: Behavioural effects of the newer antiepileptic drugs: an update.

Journal: Expert opinion on drug safety 20040101

Title: Treatment of partial seizures in childhood : an overview.

Journal: CNS drugs 20040101

Title: Electrophysiology and immunohistochemistry in the hippocampal ca1 and the dentate gyrus of rats chronically exposed to 1-bromopropane, a substitute for specific chlorofluorocarbons.

Journal: Neuroscience 20040101

Title: New antiepileptic agents.

Journal: Pediatric dentistry 20040101

Title: GABA-B receptor activation in the rat globus pallidus potently suppresses pentylenetetrazol-induced tonic seizures.

Journal: Journal of biomedical science 20040101

Title: Effect of topiramate on mechanical allodynia in neuropathic pain model in rats.

Journal: Polish journal of pharmacology 20040101

Title: Agents in development for the management of cocaine abuse.

Journal: Drugs 20040101

Title: Newer anticonvulsants in the treatment of bipolar disorder.

Journal: The Journal of clinical psychiatry 20040101

Title: Antiepileptic drugs in migraine prophylaxis: state of the art.

Journal: La Clinica terapeutica 20040101

Title: Role of the GABA transporter in epilepsy.

Journal: Advances in experimental medicine and biology 20040101

Title: Prospective open-label study of add-on and monotherapy topiramate in civilians with chronic nonhallucinatory posttraumatic stress disorder.

Journal: BMC psychiatry 20040101

Title: [New molecular targets in pharmacological treatment of anxiety disorders].

Journal: Vertex (Buenos Aires, Argentina) 20040101

Title: Low-dose tiagabine effectiveness in anxiety disorders.

Journal: MedGenMed : Medscape general medicine 20040101

Title: Therapeutic drug monitoring of old and newer anti-epileptic drugs.

Journal: Clinical chemistry and laboratory medicine 20040101

Title: [Neuroprotective activity of antiepileptic drugs].

Journal: Przeglad lekarski 20040101

Title: Non-convulsive status epilepticus associated with tiagabine therapy in children.

Journal: Seizure 20031201

Title: Tiagabine for posttraumatic stress disorder: a case series of 7 women.

Journal: The Journal of clinical psychiatry 20031201

Title: Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia.

Journal: British journal of cancer 20031117

Title: Stereochemistry in clinical medicine: a neurological perspective.

Journal: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20031101

Title: Tiagabine increases cocaine-free urines in cocaine-dependent methadone-treated patients: results of a randomized pilot study.

Journal: Addiction (Abingdon, England) 20031101

Title: Effects of antiepileptic drugs on refractory seizures in the intact immature corticohippocampal formation in vitro.

Journal: Epilepsia 20031101

Title: Tiagabine synergistically interacts with gabapentin in the electroconvulsive threshold test in mice.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031001

Title: Non-convulsive status epilepticus associated with tiagabine in a pediatric patient.

Journal: Brain & development 20031001

Title: Anticonvulsant drugs differentially suppress individual ictal signs: a pharmacokinetic/pharmacodynamic analysis in the cortical stimulation model in the rat.

Journal: Behavioral neuroscience 20031001

Title: [Clinical and neurochemical aspects of diaphragmatic myoclonus].

Journal: Neurologia (Barcelona, Spain) 20031001

Title: Tiagabine for the treatment of generalized anxiety disorder: a randomized, open-label, clinical trial with paroxetine as a positive control.

Journal: The Journal of clinical psychiatry 20031001

Title: Effects of the GABA-uptake inhibitor tiagabine in rat globus pallidus.

Journal: Experimental brain research 20030901

Title: Nonconvulsive status epilepticus due to a de novo contralateral focus during tiagabine adjunctive therapy.

Journal: Seizure 20030701

Title: [Significance of GABAA receptors for the pathophysiology and therapy of panic disorders].

Journal: Der Nervenarzt 20030701

Title: Therapeutic drug monitoring of the newer antiepileptic drugs.

Journal: Therapeutic drug monitoring 20030601

Title: Clinical and EEG findings in six patients with altered mental status receiving tiagabine therapy.

Journal: Epilepsy & behavior : E&B 20030601

Title: Clinically important drug interactions in epilepsy: general features and interactions between antiepileptic drugs.

Journal: The Lancet. Neurology 20030601

Title: GABA-ergic drugs: exit stage left, enter stage right.

Journal: Journal of psychopharmacology (Oxford, England) 20030601

Title: Interactions of tiagabine with some antiepileptics in the maximal electroshock in mice.

Journal: Pharmacology, biochemistry, and behavior 20030501

Title: The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?

Journal: Epileptic disorders : international epilepsy journal with videotape 20030501

Title: Altered gene expression in frontal cortex and midbrain of 3,4-methylenedioxymethamphetamine (MDMA) treated mice: differential regulation of GABA transporter subtypes.

Journal: Journal of neuroscience research 20030415

Title: [New epileptic treatments. Current modalities and their utilization].

Journal: Presse medicale (Paris, France : 1983) 20030308

Title: Vigabatrin, tiagabine, and visual fields.

Journal: Journal of neurology, neurosurgery, and psychiatry 20030301

Title: A controlled study comparing visual function in patients treated with vigabatrin and tiagabine.

Journal: Journal of neurology, neurosurgery, and psychiatry 20030301

Title: Pharmacodynamic analysis of the interaction between tiagabine and midazolam with an allosteric model that incorporates signal transduction.

Journal: Epilepsia 20030301

Title: Therapeutics in pediatric epilepsy, Part 1: The new antiepileptic drugs and the ketogenic diet.

Journal: Mayo Clinic proceedings 20030301

Title: Review of the newer antiepileptic drugs.

Journal: The American journal of managed care 20030301

Title: Treating bipolar depression.

Journal: The Journal of family practice 20030301

Title: Pre-clinical studies with the GABAergic compounds vigabatrin and tiagabine.

Journal: Epileptic disorders : international epilepsy journal with videotape 20030301

Title: Glutamate modulation of GABA transport in retinal horizontal cells of the skate.

Journal: The Journal of physiology 20030201

Title: Novel mechanisms of action of three antiepileptic drugs, vigabatrin, tiagabine, and topiramate.

Journal: Neurochemical research 20030201

Title: Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.

Journal: Neuroscience letters 20030102

Title: Stability of tiagabine in two oral liquid vehicles.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030101

Title: Unaltered control of extracellular GABA-concentration through GAT-1 in the hippocampus of rats after pilocarpine-induced status epilepticus.

Journal: Epilepsy research 20030101

Title: Interlaboratory variability in the quantification of new generation antiepileptic drugs based on external quality assessment data.

Journal: Epilepsia 20030101

Title: The role of GABA in anxiety disorders.

Journal: The Journal of clinical psychiatry 20030101

Title: GABA systems, benzodiazepines, and substance dependence.

Journal: The Journal of clinical psychiatry 20030101

Title: Selection criteria for the clinical use of the newer antiepileptic drugs.

Journal: CNS drugs 20030101

Title: Concurrent use of antiretrovirals and anticonvulsants in human immunodeficiency virus (HIV) seropositive patients.

Journal: Current pharmaceutical design 20030101

Title: Clinical care of pregnant women with epilepsy: neural tube defects and folic acid supplementation.

Journal: Epilepsia 20030101

Title: Newer antiepileptic drugs and cognitive issues.

Journal: Epilepsia 20030101

Title: Do antiepileptic drugs play a role in sudden unexpected death in epilepsy?

Journal: Drug safety 20030101

Title: Efficacy of newer anticonvulsant medications in bipolar spectrum mood disorders.

Journal: The Journal of clinical psychiatry 20030101

Title: Tiagabine for the treatment of anxiety.

Journal: Depression and anxiety 20030101

Title: An in vitro study of new antiepileptic drugs and astrocytes.

Journal: Epilepsia 20030101

Title: [Determinants of tiagabine (TGB) efficacy and safety. A Polish multicenter study of 1307 patients with focal epilepsy].

Journal: Neurologia i neurochirurgia polska 20030101

Title: Effects of tiagabine on cholecystokinin-tetrapeptide (CCK-4)-induced anxiety in healthy volunteers.

Journal: Depression and anxiety 20030101

Title: The role of GABA in the pathophysiology and treatment of anxiety disorders.

Journal: Psychopharmacology bulletin 20030101

Title: The evolution of antiepileptic drugs for mood stabilization and their main mechanisms of action.

Journal: Expert review of neurotherapeutics 20030101

Title: Pre- rather than co-application of vigabatrin increases the efficacy of tiagabine in hippocampal slices.

Journal: Epilepsia 20021201

Title: Antiepileptic drug therapy for adults: when to initiate and how to choose.

Journal: Mayo Clinic proceedings 20021201

Title: Relevance of new and newly rediscovered anticonvulsants for atypical forms of bipolar disorder.

Journal: Journal of affective disorders 20021201

Title: Tolerability of tiagabine: a prospective open-label study.

Journal: Epileptic disorders : international epilepsy journal with videotape 20021201

Title: New anticonvulsants: a review of applications for the management of substance abuse disorders.

Journal: Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20021201

Title: New antiepileptic drug therapies.

Journal: Neurologic clinics 20021101

Title: Treatment of posttraumatic stress disorder with tiagabine.

Journal: Canadian journal of psychiatry. Revue canadienne de psychiatrie 20021001

Title: Tiagabine in treatment refractory bipolar disorder: a clinical case series.

Journal: Bipolar disorders 20021001

Title: Antiepileptic drug use during the first 12 months of vagus nerve stimulation therapy: a registry study.

Journal: Neurology 20020924

Title: Use of anticonvulsants for treatment of neuropathic pain.

Journal: Neurology 20020910

Title: New antiepileptic drugs in childhood.

Journal: Panminerva medica 20020901

Title: [(3)H]Tiagabine binding to GABA transporter-1 (GAT-1) in suicidal depression.

Journal: Journal of affective disorders 20020901

Title: An open case series on the utility of tiagabine as an augmentation in refractory bipolar outpatients.

Journal: Journal of affective disorders 20020901

Title: Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception.

Journal: The Journal of pharmacology and experimental therapeutics 20020901

Title: Heterotopic neurons with altered inhibitory synaptic function in an animal model of malformation-associated epilepsy.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901

Title: Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI).

Journal: Epilepsy research 20020901

Title: [Characteristics and indications of tiagabine].

Journal: Revista de neurologia 20020901

Title: [Monitoring serum levels of new antiepileptics].

Journal: Revista de neurologia 20020901

Title: Selective suppression of hippocampal region hyperexcitability related to seizure susceptibility in epileptic El mice by the GABA-transporter inhibitor tiagabine.

Journal: Brain research 20020830

Title: Neuroprotective effect of tiagabine in transient forebrain global ischemia: an in vivo microdialysis, behavioral, and histological study.

Journal: Brain research 20020816

Title: Correlation between anticonvulsant activity and inhibitory action on glial gamma-aminobutyric acid uptake of the highly selective mouse gamma-aminobutyric acid transporter 1 inhibitor 3-hydroxy-4-amino-4,5,6,7-tetrahydro-1,2-benzisoxazole and its N-alkylated analogs.

Journal: The Journal of pharmacology and experimental therapeutics 20020801

Title: [Antiepileptics].

Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20020801

Title: Tiagabine, a gamma-amino-butyric acid transporter inhibitor impairs spatial learning of rats in the Morris water-maze.

Journal: Behavioural brain research 20020718

Title: Aggravation of partial seizures by antiepileptic drugs: is there evidence from clinical trials?

Journal: Neurology 20020709

Title: Tiagabine overdose can induce convulsive status epilepticus.

Journal: Epilepsia 20020701

Title: Tiagabine-related non-convulsive status epilepticus in partial epilepsy: three case reports and a review of the literature.

Journal: Seizure 20020601

Title: Effects of antiepileptic drugs on visual function, with special reference to Vigabatrin.

Journal: Acta ophthalmologica Scandinavica 20020601

Title: Effects of tiagabine, a gamma-aminobutyric acid re-uptake inhibitor, on normal rat bladder function.

Journal: The Journal of urology 20020501

Title: Contribution of GABAergic cortical circuitry in shaping somatosensory evoked scalp responses: specific changes after single-dose administration of tiagabine.

Journal: Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20020501

Title: [New antiepileptic drugs: new therapeutic options].

Journal: Revue neurologique 20020501

Title: Anxiolytic-like effects of acute and chronic GABA transporter inhibition in rats.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20020501

Title: The importance of drug interactions in epilepsy therapy.

Journal: Epilepsia 20020401

Title: Occurrence of psychosis in patients with epilepsy randomized to tiagabine or placebo treatment.

Journal: Epilepsia 20020401

Title: Free-choice ethanol consumption under the influence of GABAergic drugs in rats.

Journal: Alcoholism, clinical and experimental research 20020401

Title: Third generation anticonvulsants in bipolar disorder: a review of efficacy and summary of clinical recommendations.

Journal: The Journal of clinical psychiatry 20020401

Title: The 'number needed to treat' with levetiracetam (LEV): comparison with the other new antiepileptic drugs (AEDs).

Journal: Seizure 20020401

Title: [Adult GM2 gangliosidosis: improvement of ataxia with GABAergic drugs].

Journal: Neurologia (Barcelona, Spain) 20020301

Title: Visual field defects.

Journal: Seizure 20020301

Title: Tiagabine in glial tumors.

Journal: Epilepsy research 20020301

Title: Recurrent complex partial status epilepticus associated with tiagabine rechallenge.

Journal: Acta neurologica Belgica 20020301

Title: Some common issues in the use of antiepileptic drugs.

Journal: Seminars in neurology 20020301

Title: New antiepileptic drugs.

Journal: The neurologist 20020301

Title: Marketed new antiepileptic drugs: are they better than old-generation agents?

Journal: Therapeutic drug monitoring 20020201

Title: New antiepileptic drugs: review on drug interactions.

Journal: Therapeutic drug monitoring 20020201

Title: Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1.

Journal: British journal of pharmacology 20020101

Title: Increased [(3)H]tiagabine binding to GAT-1 in the cingulate cortex in schizophrenia.

Journal: Neuropsychobiology 20020101

Title: Appropriate use of medications for seizures. Guiding principles on the path of efficacy.

Journal: Postgraduate medicine 20020101

Title: The use of tiagabine in affective disorders.

Journal: Pharmacopsychiatry 20020101

Title: Seizures in HIV-seropositive individuals: epidemiology and treatment.

Journal: CNS drugs 20020101

Title: Anticonvulsants: aspects of their mechanisms of action.

Journal: European journal of pain (London, England) 20020101

Title: Non-convulsive status epilepticus induced by tiagabine in a patient with pseudoseizure.

Journal: Seizure 20020101

Title: Effect of antiepileptic drugs on cognitive function in individuals with epilepsy: a comparative review of newer versus older agents.

Journal: Drugs 20020101

Title: Effects of tiagabine and diazepam on operant ethanol self-administration in the rat.

Journal: Journal of studies on alcohol 20020101

Title: Interactions between antiepileptic drugs and hormonal contraception.

Journal: CNS drugs 20020101

Title: Cellular mechanisms of pharmacoresistance in slices from epilepsy surgery.

Journal: Novartis Foundation symposium 20020101

Title: Mood disorders in patients with epilepsy: epidemiology and management.

Journal: CNS drugs 20020101

Title: Treatment of epilepsy in women of reproductive age: pharmacokinetic considerations.

Journal: Clinical pharmacokinetics 20020101

Title: Tiagabine add-on for drug-resistant partial epilepsy.

Journal: The Cochrane database of systematic reviews 20020101

Title: New and emerging prophylactic agents for migraine.

Journal: CNS drugs 20020101

Title: The use of tiagabine augmentation for treatment-resistant anxiety disorders: a case series.

Journal: Psychopharmacology bulletin 20020101

Title: Pharmacokinetics of mood stabilizers and new anticonvulsants.

Journal: Psychopharmacology bulletin 20020101

Title: Rat models of genetic absence epilepsy: what do EEG spike-wave discharges tell us about drug effects?

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: New migraine preventive options: an update with pathophysiological considerations.

Journal: Revista do Hospital das Clinicas 20020101

Title: Action of 4-amino-2-fluorobutanoic acid and other structural analogues on gamma-aminobutyric acid transport by channel catfish brain.

Journal: Journal of basic and clinical physiology and pharmacology 20020101

Title: Neuroprotective effects of antiepileptic drugs.

Journal: Polish journal of pharmacology 20020101

Title: Effectiveness of adjunctive therapy with tiagabine in mentally disabled patients with epilepsy.

Journal: Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101

Title: Newer anticonvulsant drugs in neuropathic pain and bipolar disorder.

Journal: Journal of pain & palliative care pharmacotherapy 20020101

Title: Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy.

Journal: Epilepsy research 20011201

Title: Treatment of painful sensory neuropathy with tiagabine: a pilot study.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20011201

Title: Clinical pharmacology and therapeutic use of the new antiepileptic drugs.

Journal: Fundamental & clinical pharmacology 20011201

Title: [Monitoring of renal function in epileptic children and teenagers treated with valproic acid or carbamazepine in concomitant therapy with tiagabine].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20011201

Title: Review of treatment options for refractory epilepsy: new medications and vagal nerve stimulation.

Journal: Epilepsy research 20011101

Title: [Experience with tiagabine in the clinical practice; new insights as to the efficacy and safety profile].

Journal: Der Nervenarzt 20011001

Title: Visual fields and tiagabine: a quandary.

Journal: Seizure 20011001

Title: Drug-induced nonconvulsive status epilepticus with low dose of tiagabine.

Journal: Epileptic disorders : international epilepsy journal with videotape 20010901

Title: Newer antiepileptic drugs: advantages and disadvantages.

Journal: Brain & development 20010801

Title: Tiagabine improves panic and agoraphobia in panic disorder patients.

Journal: The Journal of clinical psychiatry 20010801

Title: Visual field constriction: accumulation of vigabatrin but not tiagabine in the retina.

Journal: Neurology 20010724

Title: Improvement of stiff-person syndrome with tiagabine.

Journal: Neurology 20010724

Title: Anti-ischemic and cognition-enhancing properties of NNC-711, a gamma-aminobutyric acid reuptake inhibitor.

Journal: European journal of pharmacology 20010713

Title: Advances in the treatment of epilepsy.

Journal: American family physician 20010701

Title: Effect of tiagabine and topiramate on porphyrin metabolism in an in vivo model of porphyria.

Journal: Pharmacology & toxicology 20010701

Title: Transient dystonias in three patients treated with tiagabine.

Journal: Epilepsia 20010701

Title: Tiagabine treatment and DNA damage in rat astrocytes: an in vitro study by comet assay.

Journal: Neuroscience letters 20010622

Title: Synthesis of novel gamma-aminobutyric acid (GABA) uptake inhibitors. 5.(1) Preparation and structure-activity studies of tricyclic analogues of known GABA uptake inhibitors.

Journal: Journal of medicinal chemistry 20010621

Title: Efficacy of background GABA uptake in rat hippocampal slices.

Journal: Neuroreport 20010613

Title: Tiagabine, a specific gamma-aminobutyric acid transporter-1 inhibitor, in the treatment of psychosis.

Journal: Journal of clinical psychopharmacology 20010601

Title: Comparison of twice- and three times daily tiagabine for the adjunctive treatment of partial seizures in refractory patients with epilepsy: an open label, randomised, parallel-group study.

Journal: Epileptic disorders : international epilepsy journal with videotape 20010601

Title: [An open study of tiagabine in partial epilepsy].

Journal: Revista de neurologia 20010601

Title: Tiagabine: efficacy and safety in adjunctive treatment of partial seizures.

Journal: Epilepsia 20010401

Title: Second generation anticonvulsant medications: their use in children.

Journal: The Journal of school nursing : the official publication of the National Association of School Nurses 20010401

Title: Status epilepticus and tiagabine therapy: review of safety data and epidemiologic comparisons.

Journal: Epilepsia 20010301

Title: Assessing tinnitus and prospective tinnitus therapeutics using a psychophysical animal model.

Journal: Journal of the Association for Research in Otolaryngology : JARO 20010301

Title: Metabolic distinction between vesicular and cytosolic GABA in cultured GABAergic neurons using 13C magnetic resonance spectroscopy.

Journal: Journal of neuroscience research 20010215

Title: Localization and pharmacological characterization of voltage dependent calcium channels in cultured neocortical neurons.

Journal: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20010201

Title: Non-convulsive status epilepticus in two patients receiving tiagabine add-on treatment.

Journal: Journal of neurology 20010201

Title: [Antiepileptic drugs and neuropathic pain].

Journal: Revista de neurologia 20010201

Title: Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V).

Journal: Epilepsy research 20010101

Title: The GABA uptake inhibitor tiagabine promotes slow wave sleep in normal elderly subjects.

Journal: Neurobiology of aging 20010101

Title: [Controversies about the new anti-epileptic drugs].

Journal: Revista de neurologia 20010101

Title: Pharmacology and clinical experience with tiagabine.

Journal: Expert opinion on pharmacotherapy 20010101

Title: Pharmacologic management of epilepsy in the elderly.

Journal: Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 20010101

Title: Effects of antiepileptic drugs on cognition.

Journal: Epilepsia 20010101

Title: Behavioural effects of the new anticonvulsants.

Journal: Drug safety 20010101

Title: Antiepileptogenic agents: how close are we?

Journal: Drugs 20010101

Title: The new generation of GABA enhancers. Potential in the treatment of epilepsy.

Journal: CNS drugs 20010101

Title: GABAergic mechanisms in epilepsy.

Journal: Epilepsia 20010101

Title: Epileptic encephalopathy.

Journal: Epilepsia 20010101

Title: Management strategies for refractory localization-related seizures.

Journal: Epilepsia 20010101

Title: The management of refractory idiopathic epilepsies.

Journal: Epilepsia 20010101

Title: Tiagabine in clinical practice.

Journal: Epilepsia 20010101

Title: Long-term safety of tiagabine.

Journal: Epilepsia 20010101

Title: Tiagabine (gabitril) experience in children.

Journal: Epilepsia 20010101

Title: Epilepsy in the elderly: the use of tiagabine.

Journal: Epilepsia 20010101

Title: The short-term impact of adjunctive tiagabine on health-related quality of life.

Journal: Epilepsia 20010101

Title: Antiepileptic drugs for the acute and maintenance treatment of bipolar disorder.

Journal: Harvard review of psychiatry 20010101

Title: Concerns with antiepileptic drug initiation: safety, tolerability, and efficacy.

Journal: Epilepsia 20010101

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Journal: Neurologia i neurochirurgia polska 20010101

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Journal: Medicine and law 20010101

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Journal: Akusherstvo i ginekologiia 20010101

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Title: Preclinical evaluation of newly approved and potential antiepileptic drugs against cocaine-induced seizures.

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Title: Effects of new anticonvulsant medications on porphyrin synthesis in cultured liver cells: potential implications for patients with acute porphyria.

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Title: 1-(3-(9H-carbazol-9-yl)-1-propyl)-4-(2-methoxyphenyl)-4-piperidinol, a novel subtype selective inhibitor of the mouse type II GABA-transporter.

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Title: Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1.

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