Title: Identification of 2-oxatriazines as highly potent pan-PI3K/mTOR dual inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20110815
Title: Antitumor efficacy profile of PKI-402, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor.
Journal: Molecular cancer therapeutics 20100401
Title: Lead optimization of N-3-substituted 7-morpholinotriazolopyrimidines as dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors: discovery of PKI-402.
Journal: Journal of medicinal chemistry 20100128
Title: Mallon R et al. Antitumor efficacy profile of PKI-402, a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor. Mol Cancer Ther. 2010 Apr;9(4):976-84.
